Why Stephen Meyer Thinks DNA Points to a Mind — Transcript
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- 0:00Now maybe the most exciting of all the
- 0:01discovery stories for for Cambridge is
- 0:03the dis is the Watson and Crick story
- 0:05and the whole story of what's called the
- 0:07molecular biological revolution. And
- 0:09this is the third big discovery that I
- 0:11talk about that's not compatible with
- 0:13the scientific materialism of Richard
- 0:15Dawkins. The fine-tuning isn't by the
- 0:17way as well. It's not a property you
- 0:18would expect if you were trying to
- 0:20explain the universe by reference to
- 0:22blind pitiles indifference. Um the the
- 0:26go-to atheistic explanation now is that
- 0:28there's a gabillion other universes out
- 0:30there and we just happen to be in the
- 0:31lucky one where all the fine-tuning
- 0:33parameters got just right. Um we can
- 0:35talk about that in the Q&A if you like.
- 0:38In any case, the big discovery that
- 0:40perhaps the most famous of all the
- 0:41discoveries with god-friendly
- 0:42implications was the the discovery of
- 0:45DNA and not just this the structure of
- 0:48DNA which was first discovered here in
- 0:491953 but also the discovery that DNA
- 0:52contains digital information in uh an
- 0:57alphabetic or digital form. The
- 0:59discovery was first made by Watson and
- 1:01Crick. The elucidation of the of the DNA
- 1:05structure was first made by Watson and
- 1:06Crick in 1953. And their famous model
- 1:10involved uh what was called a sugar
- 1:12phosphate backbone and then what were
- 1:16called bases that were carrying
- 1:18information along the inside of the of
- 1:19of the molecule. In in on February 28th,
- 1:241953,
- 1:26they walked into a pub, the Eagle Pub.
- 1:28Some of us have been talking about ma of
- 1:31going there and having a pint to
- 1:33celebrate. It's pretty it's this was
- 1:35also the watering hole of William
- 1:36William Wilburforce by the way. Um and
- 1:39it's just it's just steps away from that
- 1:41Caendish door which I think is is lovely
- 1:44because inside the Caendish laboratory
- 1:46you can look in the window where Watson
- 1:48and Crick were doing their modeling. And
- 1:51so if you find the door, look in the
- 1:52window to the right and you'll see where
- 1:54they were working out the structure of
- 1:56the DNA molecule. The day they they they
- 1:59figured it out and it clic all the
- 2:00pieces clicked into place, Crick stood
- 2:03back and said, "It's so beautiful. It's
- 2:06got to be right." And so they walked
- 2:09down the street just a few hundred steps
- 2:10to the Eagle Pub and announced to the
- 2:13people there drinking that they had
- 2:16discovered the secret of life. I don't
- 2:18know if it was drinks on the house or
- 2:20not, but it was a, you know, quite quite
- 2:22an atmosphere. And today you'll right
- 2:24outside the pub you'll see a plaque uh
- 2:27and you can see that if you go on the
- 2:30well this this this these pictures are
- 2:31in your self-guided walking tour. Now I
- 2:35think an even more significant discovery
- 2:37was made by by Francis Crick 5 years
- 2:41later in in 1958. He formulated
- 2:44something called the sequence
- 2:46hypothesis.
- 2:47And what he realized was that along the
- 2:51interior of that twisting double helix
- 2:54were chemical subunits of the molecule
- 2:58that were functioning like alphabetic
- 3:01characters in a written language or
- 3:03digital characters, zeros and ones in a
- 3:05section of m machine code. You may know
- 3:07that Bill Gates has said the DNA is like
- 3:09a software program but much more complex
- 3:11than any we've ever written. It's pretty
- 3:14suggestive remark. We'll come back to
- 3:15that. And Crick uh was the first to
- 3:18realize that DNA is containing
- 3:21information in a digital form. And what
- 3:23he thought the information was doing was
- 3:25providing instructions for building the
- 3:28big protein molecules that are crucial
- 3:31to keeping living cells alive. You may
- 3:34have seen some of my my uh visual aids
- 3:37on this, but proteins are made of
- 3:38smaller subunits called amino acids. And
- 3:41if they're arranged just right, then the
- 3:44forces between them will c cause these
- 3:46long chain-like molecules to fold into
- 3:48very specific shapes. And then those
- 3:51shapes will perform uh if the if the
- 3:54shapes are right, then they have a hand
- 3:55and gloves fit with other molecules in
- 3:58the cell. And uh and then they'll do a
- 4:01job and they do lots of jobs. They do
- 4:03all the important jobs. You can think of
- 4:04proteins as like the toolbox of the
- 4:06cell. just as in the toolbox we have a
- 4:08hammer and a and a and a and and a
- 4:10wrench and a saw and they do jobs in
- 4:12virtue of their their their
- 4:14three-dimensional shape and structure.
- 4:16Well, the same thing is true in the
- 4:17proteins. Some of them catalyze
- 4:19reactions. Some of them um express the
- 4:22information on DNA. Others of them form
- 4:24the parts of miniature machines that
- 4:26cells need to stay alive. So there's all
- 4:28this intricate machinery in cells and
- 4:30it's all made from and and and the
- 4:33machines are made of the proteins and
- 4:35the proteins are constructed as a result
- 4:37of the information on the DNA molecule.
- 4:41So good analogy would be um something
- 4:44like are people familiar with digital
- 4:46printers? Do you are you familiar with
- 4:48those the way now we can yeah we can use
- 4:50digital code and the printers will print
- 4:52they don't print out paper they print
- 4:53out you know pieces of garage doors or
- 4:56or you physical objects that do things
- 5:00or engineers here will be familiar with
- 5:02the CAD CAM technology computer assisted
- 5:04design and engineering in Seattle we
- 5:06have Boeing and at Boeing the the uh the
- 5:09the engineers will write code the code
- 5:11will go down a wire it will be converted
- 5:13into another machine language that can
- 5:15be read at a manufacturing apparatus And
- 5:17then the manufacturing apparatus will
- 5:20put the the for example the rivets on
- 5:22the airplane wing in just the right
- 5:24place in accord with the specifications
- 5:26of the code written by the engineer. So
- 5:29we use we do this all the time now. We
- 5:30have digital information directing the
- 5:33construction of mechanical parts and
- 5:34systems. That's what's going on inside
- 5:37cells. And that's what Crick first
- 5:41realized and it was later confirmed by a
- 5:43whole series of really fascinating exper
- 5:44experiments. Now, one of the other
- 5:46scientists who was here at Cambridge was
- 5:48the guy who figured out what the
- 5:50proteins were doing. And so, you have
- 5:52the DNA guys and the protein guys right
- 5:54here at the same time figuring it all
- 5:56out. And now there's a a laboratory that
- 5:59and the guy, one of the key guys here
- 6:01was named Max Perutes. He got the Nobel
- 6:03Prize in 1962 for his work on protein
- 6:06structure. Watson Crick got their Nobel
- 6:08Prize about the same time. and they now
- 6:10this this period of immense scientific
- 6:13creativity which was almost all
- 6:15happening here although Rockefeller
- 6:17Institute got into it some people in
- 6:19France as well but it was it's an
- 6:20amazing story how they how they
- 6:22uncracked this what's really fun is that
- 6:25Francis Crick was a codereaker in World
- 6:28War II and he ended up breaking the
- 6:30ultimate code the irony is that Crick
- 6:33and Watson were also strict scientific
- 6:36materialists they were atheists and they
- 6:38were looking for the material basis is
- 6:40for life. And they thought they found it
- 6:43in 1953
- 6:45until Crick realized it's not just a
- 6:47molecule.
- 6:49It's a molecule that contains code.
- 6:52And that discovery ends up being
- 6:55foundational. It provides evidence of
- 6:57what we're going to call intelligent
- 6:59design. And it it's it has created a
- 7:01complete impass in evolutionary theory.
- 7:03people cannot account for the origin of
- 7:05the information needed to build the
- 7:07first life or subsequent forms of life.
- 7:09I don't know if if Doug is here in the
- 7:11room. Uh we'll hear a little bit later
- 7:13in the week from Doug. He's another
- 7:16great Cambridge scientist and I don't
- 7:18say that just because he's my friend. He
- 7:21did an amazing bit of work here for 14
- 7:23years and he interacted with Max
- 7:25Perutes. He was in the laboratory that
- 7:26Watson Crick and Perutes and others
- 7:28founded called the LL uh uh the
- 7:31laboratory for molecular biology. right
- 7:33here. And so we'll hear a bit more of
- 7:34Doug's story later in the week. But in
- 7:37any case, even though Watson and Crick
- 7:39were looking for the material foundation
- 7:41for life, what they actually found was
- 7:43something more like software. And and
- 7:46Bill Gates has said the DNA is like a
- 7:48computer program, but far more advanced
- 7:50than ever any we've ever created. And
- 7:52this is where
- 7:55sort of this part of the story
- 7:57intersects with my story. I was I
- 8:00attended this conference that I
- 8:01mentioned in Dallas in 1985. I heard the
- 8:03cosmologists talking about the evidence
- 8:05for a creation event. But I also heard
- 8:08scientists talking about the question of
- 8:09the origin of life and how the new
- 8:11discoveries in molecular biology about
- 8:13the informationbearing properties of DNA
- 8:17had completely changed the terms of
- 8:19debate.
- 8:20Turns out by the mid80s no one could
- 8:23understand where this information had
- 8:24come from. That was the thing they
- 8:27couldn't explain. If you want to explain
- 8:28the origin of the first life from
- 8:29simpler non-living chemicals, well,
- 8:32that's all great. You can imagine the
- 8:33chemicals knocking into each other, but
- 8:35how are chemical undirected chemical
- 8:37reactions going to get you code? That
- 8:40didn't seem very plausible. And one of
- 8:43the scientists at this conference had
- 8:45just written a book called The Mystery
- 8:46of Life's Origin. And in the epilogue to
- 8:48that book, he suggested that the
- 8:51information that was proving so
- 8:53perplexing to everyone trying to explain
- 8:55the origin of life was not evidence of
- 8:58an undirected chemical process, but
- 9:01rather
- 9:03possibly the product of what he called
- 9:05an intelligent cause. And this was Dr.
- 9:08Charles Thaxton who is in in Dallas. And
- 9:11his his reasoning was very
- 9:13straightforward. He said in our
- 9:14experience information is a mind
- 9:17product. Software comes from programmers
- 9:20after all. So maybe you we've been
- 9:23working for two decades trying to
- 9:24explain the origin of the information in
- 9:26DNA as a result of chemical reactions.
- 9:28And the chemistry doesn't want to do
- 9:29that. The chemistry is Jim Tour you may
- 9:32have seen him online says chemistry
- 9:34doesn't care about life. It doesn't want
- 9:35to move in a life- friendly direction.
- 9:38And so Thaxton suggested, well, maybe
- 9:40what we're seeing is evidence of an
- 9:42intelligent cause. Well, I attended the
- 9:44conference, friends introduced me
- 9:46afterwards, and I started going to his
- 9:48office late at night. And over the
- 9:50ensuing year, I received some very, very
- 9:54uh consequential mentoring. And by the
- 9:58time I got to applying for a Rotary
- 10:02scholarship to come to Cambridge, I
- 10:03already knew what I wanted to work on. I
- 10:05wanted to work on this origin of life
- 10:07question specifically with the with
- 10:09wondering whether there might be
- 10:11evidence of actual intelligent design.
- 10:14Was it possible I was wondering that you
- 10:16could formulate a scientific theory or
- 10:19scientific argument for intelligent
- 10:21design? Now arguably the person that
- 10:23helped me think this through most was
- 10:26another Cambridge person again Charles
- 10:28Darwin. And even though I disagreed with
- 10:31his his theory about the origin of the
- 10:34origin of new forms of life is he had
- 10:36developed a method of reasoning that
- 10:39directly applied to this origin
- 10:41question. It was a method of historical
- 10:43scientific reasoning rather than sitting
- 10:45at the at at the laboratory bench and
- 10:48trying to get some process to uh occur
- 10:51under controlled laboratory conditions.
- 10:53What historical scientists tried to do
- 10:54is look at clues and reason back to what
- 10:57might have caused those clues to emerge.
- 11:00My PhD thesis ended up being called of
- 11:02clues and causes. And so how do you get
- 11:05from the clues back to the causes? And
- 11:07Darwin said, "Well, there's a way. What
- 11:09you want to do is you want to infer the
- 11:13best explanation. We don't get to see
- 11:15what happened, but we know something
- 11:17about cause and effect. And so we can
- 11:18figure out what is the most likely cause
- 11:21of a given effect that we're looking at
- 11:22in the in the present if we know how
- 11:25cause and effect works. And while I was
- 11:27working at that uh there at that there
- 11:30was a young professor from the United
- 11:31States who came to do a a job talk here
- 11:34to candidate for a position in my
- 11:36department the department of philosophy
- 11:37of science here at Cambridge. He ended
- 11:39up getting the job and he left behind a
- 11:41manuscript for me called inference to
- 11:43the best explanation
- 11:45and he later came and actually rose to
- 11:47the to become the the head of the
- 11:49department and um what Lip Peter Lipton
- 11:53was his name and what he highlighted was
- 11:54a question philosophers were asking.
- 11:56Yes, we see the scientists are doing
- 11:58this inferring to the best explanation
- 12:00method.
- 12:02But what makes him an explanation best
- 12:05and as I got deeper into his work and
- 12:07some of the work of the 19th century uh
- 12:10philosophers and scientists I found a
- 12:13consensus was actually already present
- 12:15that the best explanation is the one
- 12:17that posits a cause which is known to
- 12:20produce the effect in question. I found
- 12:22this in the work of H William Hule for
- 12:25whom we're naming our center and also in
- 12:27the work of Charles Lyel a famous
- 12:29geologist whose work Darwin read on the
- 12:32beagle and when I saw the title page of
- 12:37of Lyel's book a light went on for me.
- 12:39Here's here's a long Victorian title. It
- 12:42says the principles of geology being an
- 12:44attempt to explain the former changes of
- 12:46the earth's surface by reference to
- 12:48causes now in operation.
- 12:51I got to causes now and oh we explain
- 12:54what's what we see today by reference to
- 12:56causes that we know produce that thing
- 12:57causes we see at work today so I asked
- 12:59myself a question what is the cause now
- 13:02in operation that produces digital code
- 13:06and I realized there was only one was a
- 13:08mind it was an intelligence whenever we
- 13:10see information especially if it's an
- 13:13alphabetic or digital form whether it's
- 13:16in a hieroglyphic inscription like the
- 13:18Rosetta Stone at the British Museum or a
- 13:21newspaper headline or a section of
- 13:23software code or information embedded in
- 13:25a radio signal.
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