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What is ventricle fibrillation (Vfib)? | Circulatory System and Disease | NCLEX-RN | Khan Academy — Transcript

by khanacademymedicine · 1,333 words · 185 segments · language en · Watch on YouTube

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  1. 0:01- [Voiceover] Let's talk about ventricular fibrillation,
  2. 0:03also known as V-fib.
  3. 0:06This is an abnormal, deadly heart rhythm,
  4. 0:09where the ventricles, which I'm outlining right here,
  5. 0:12these lower chambers of the heart,
  6. 0:13the ventricles lose the ability to contract
  7. 0:16and circulate blood to the rest of the body,
  8. 0:20and that's why V-fib is so deadly.
  9. 0:23So, over here we have a heart diagram,
  10. 0:25looking at the inside of the heart,
  11. 0:26just like we did on the left,
  12. 0:28but this diagram on the right highlights
  13. 0:30some of the important structures
  14. 0:32in the electrical conduction system.
  15. 0:35And I've taken out the big vessels,
  16. 0:37so that way you can get a better view
  17. 0:38of the inside of the heart.
  18. 0:40So, in a normal heart, the electrical conduction
  19. 0:42starts at the sinoatrial node, also known as the SA node.
  20. 0:48So, sinoatrial, SA node.
  21. 0:53The signal travels from the SA node
  22. 0:55down to another structured called
  23. 0:58the atrioventricular or AV node.
  24. 1:03So, that stands for atrioventricular or AV node.
  25. 1:11From the AV node, the signal goes down to the ventricles
  26. 1:15and signals to the ventricles
  27. 1:16and makes the ventricular cells and the walls contract.
  28. 1:21When these walls contract, that's when blood
  29. 1:22is pushed out to the rest of the body.
  30. 1:25Now in V-fib, the signal in the ventricles
  31. 1:27is no longer coordinated.
  32. 1:29This might be because you have some sort of
  33. 1:32severe oxygen deprivation or because you have
  34. 1:35some sort of abnormality in conduction,
  35. 1:37but for whatever reason,
  36. 1:38you lose coordinated signaling in the ventricles.
  37. 1:41Instead, you have this rapid, random, and chaotic signaling.
  38. 1:46This chaotic signaling leads to
  39. 1:48the ventricular walls spasming,
  40. 1:52and when the ventricular walls spasm,
  41. 1:54blood can't be circulated through the body.
  42. 1:57It just stays here in the heart.
  43. 1:59If you're not circulating blood to the rest of the body,
  44. 2:01you're depriving all of the other organs of oxygen.
  45. 2:05Another way to think about this is,
  46. 2:07think about if you were squeezing a tube of toothpaste.
  47. 2:11So, here you have a hand squeezing a tube of toothpaste,
  48. 2:14and you can imagine that if you squeeze
  49. 2:17with all your fingers at the same time,
  50. 2:20you're going to get the most toothpaste out.
  51. 2:24So, if you coordinate all your fingers
  52. 2:26to squeeze at the same time,
  53. 2:27you're going to squeeze out the most toothpaste,
  54. 2:29as opposed to if you squeezed your pinky
  55. 2:32and then your index finger and then your thumb,
  56. 2:35you're not going to squeeze out a bunch of toothpaste.
  57. 2:37This is the same idea as ventricular fibrillation.
  58. 2:39You lose this coordinated contraction
  59. 2:41and this coordinated squeeze
  60. 2:42to distribute blood to the rest of the body,
  61. 2:44and instead you have random firing of muscle cells,
  62. 2:46leading to this spasm,
  63. 2:48and you're not going to push out a lot of toothpaste
  64. 2:51or blood to the rest of the body.
  65. 2:53If V-fib isn't reversed immediately through electric shock,
  66. 2:56you're going to have permanent brain damage and death,
  67. 3:02because the brain and the body
  68. 3:03aren't getting enough oxygen.
  69. 3:05A person whose heart is in V-fib
  70. 3:08is not going to be conscious,
  71. 3:09since they have no blood circulating,
  72. 3:12and you won't be able to feel a pulse.
  73. 3:14Pulses are made by forward movement
  74. 3:17of blood to the vessels, so if you have no
  75. 3:19forward movement of blood to the vessels,
  76. 3:20you're not going to have a pulse.
  77. 3:22Sometimes, right before someone collapses
  78. 3:24from ventricular fibrillation,
  79. 3:25they might complain of signs or symptoms of a heart attack,
  80. 3:29like chest pain or numbness or tingling in their left arm,
  81. 3:33and that's because the heart is getting deprived of oxygen.
  82. 3:37Since the heart's not circulating blood
  83. 3:39to the rest of the body,
  84. 3:40it can't circulate blood to the heart itself,
  85. 3:43and since skin isn't getting oxygenated blood,
  86. 3:45you might see the skin turn pale or even a blue color.
  87. 3:51This is also known as cyanosis.
  88. 3:53That's the blue-color skin when you're not
  89. 3:55circulating oxygen through the body.
  90. 3:58An EKG in someone in V-fib looks like this.
  91. 4:01You're going to see course squiggly lines.
  92. 4:04This is because you lose this smooth signaling
  93. 4:07from the SA node to the AV node to the ventricles.
  94. 4:10Instead, in the ventricles you have this
  95. 4:12chaotic, erratic signaling,
  96. 4:14which looks like course squiggly lines on EKG.
  97. 4:17The ventricles are just spasming.
  98. 4:21Now, what are the big risk factors of V-fib?
  99. 4:24Well, I like to separate
  100. 4:25the major risk factors into two categories.
  101. 4:27The first one being anything that causes
  102. 4:30general irritability to the ventricular cells.
  103. 4:33Now, an irritable ventricular cell means
  104. 4:35that it's likely to just over-fire or fire abnormally.
  105. 4:42The other risk factors for V-fib is
  106. 4:44anything that causes scar tissue formation.
  107. 4:49Now, let's go back to the irritable ventricular cells.
  108. 4:51What would cause ventricular cells to be irritated?
  109. 4:54Well, the most classic example is coronary artery disease.
  110. 4:59Coronary arteries are the blood vessels
  111. 5:01that supply the heart with oxygenated blood,
  112. 5:04and over time these blood vessels can get clogged,
  113. 5:07and this might be because of years of smoking
  114. 5:09or bad diet, but over time these vessels get clogged.
  115. 5:14When the coronary arteries are clogged,
  116. 5:16you've got less blood flow to the ventricular cells.
  117. 5:19These cells get less oxygen than they're used to having,
  118. 5:22so they become irritated,
  119. 5:24and they're more likely to over-fire or fire abnormally.
  120. 5:28Also, certain electrolyte abnormalities,
  121. 5:31like high potassium or low calcium or low magnesium
  122. 5:36might cause ventricular cells to become irritable.
  123. 5:39And why is that?
  124. 5:41Well, electrolytes play an important role
  125. 5:43of normal electric conduction in the heart.
  126. 5:45And you can imagine if the electrolytes
  127. 5:47don't have the right levels,
  128. 5:49this could disrupt normal electric conduction
  129. 5:51through the heart.
  130. 5:53Okay, and now for scar tissue.
  131. 5:55So, we said scar tissue can also set up the heart
  132. 5:58for ventricular fibrillation.
  133. 5:59So, what might cause scar tissue?
  134. 6:01Well, the most classic example is a heart attack.
  135. 6:06Like we said, we have coronary arteries
  136. 6:08that supply the heart with oxygenated blood.
  137. 6:12When you have a heart attack,
  138. 6:14there is a coronary artery that gets clogged, totally,
  139. 6:18so no blood is getting to this part of the heart.
  140. 6:22So, whereas in coronary artery disease
  141. 6:25you had less blood flow,
  142. 6:27in heart attack you have no blood flow
  143. 6:30to this part of the heart, and this tissue ends up dying,
  144. 6:35and it's replaced by protein, kind of like a scab,
  145. 6:39and it creates this scar tissue.
  146. 6:41Now, scar tissue doesn't function like regular heart tissue.
  147. 6:45It's not going to conduct signal
  148. 6:48like regular heart tissue would.
  149. 6:49Instead, it sets up for abnormal firing
  150. 6:52or abnormal circuits in the heart.
  151. 6:55And this disruption in electrical conduction
  152. 6:57can set up the heart for ventricular fibrillation.
  153. 7:00Other things that can lead to scar tissue formation
  154. 7:03is a cardiomyopathy.
  155. 7:07So, cardiomyopathy just means disease of heart tissue,
  156. 7:10in which the heart tissue doesn't function as well.
  157. 7:14So, it loses function.
  158. 7:17It doesn't lose all function,
  159. 7:19but it doesn't function as well as a normal heart would.
  160. 7:22Cardiomyopathies have a lot of causes.
  161. 7:24So, infection can be a cause.
  162. 7:26So, there are some viruses that affect the heart
  163. 7:29and make the heart tissue actually decrease function.
  164. 7:33There are certain genetic disorders
  165. 7:36that can cause a cardiomyopathy,
  166. 7:40and these disorders will actually change the structure
  167. 7:43of the tissue of the heart, making them lose function,
  168. 7:47and also years of coronary artery disease,
  169. 7:49which I'm going to write as CAD,
  170. 7:52so, years of coronary artery disease,
  171. 7:54where the heart is constantly getting less oxygen
  172. 7:57than it optimally wants over years.
  173. 7:59Eventually, that heart tissue is going to lose function.
  174. 8:03Again, all of these things from the cardiomyopathies
  175. 8:05predispose the heart to have scar formation,
  176. 8:08and scar disrupts normal electrical conduction
  177. 8:12and can set the heart up for V-fib.
  178. 8:14And one final thing that might cause ventricular fibrillation
  179. 8:17that's not as common is electrocution.
  180. 8:22In electrocution, you have some sort of
  181. 8:24outside source of electricity entering the body.
  182. 8:27So, where the heart would have a normal
  183. 8:28electrical conduction system,
  184. 8:30electrocution is going to disrupt this normal signaling,
  185. 8:37and that can lead to ventricular fibrillation.

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