What is ventricle fibrillation (Vfib)? | Circulatory System and Disease | NCLEX-RN | Khan Academy — Transcript
Full transcript
- 0:01- [Voiceover] Let's talk about ventricular fibrillation,
- 0:03also known as V-fib.
- 0:06This is an abnormal, deadly heart rhythm,
- 0:09where the ventricles, which I'm outlining right here,
- 0:12these lower chambers of the heart,
- 0:13the ventricles lose the ability to contract
- 0:16and circulate blood to the rest of the body,
- 0:20and that's why V-fib is so deadly.
- 0:23So, over here we have a heart diagram,
- 0:25looking at the inside of the heart,
- 0:26just like we did on the left,
- 0:28but this diagram on the right highlights
- 0:30some of the important structures
- 0:32in the electrical conduction system.
- 0:35And I've taken out the big vessels,
- 0:37so that way you can get a better view
- 0:38of the inside of the heart.
- 0:40So, in a normal heart, the electrical conduction
- 0:42starts at the sinoatrial node, also known as the SA node.
- 0:48So, sinoatrial, SA node.
- 0:53The signal travels from the SA node
- 0:55down to another structured called
- 0:58the atrioventricular or AV node.
- 1:03So, that stands for atrioventricular or AV node.
- 1:11From the AV node, the signal goes down to the ventricles
- 1:15and signals to the ventricles
- 1:16and makes the ventricular cells and the walls contract.
- 1:21When these walls contract, that's when blood
- 1:22is pushed out to the rest of the body.
- 1:25Now in V-fib, the signal in the ventricles
- 1:27is no longer coordinated.
- 1:29This might be because you have some sort of
- 1:32severe oxygen deprivation or because you have
- 1:35some sort of abnormality in conduction,
- 1:37but for whatever reason,
- 1:38you lose coordinated signaling in the ventricles.
- 1:41Instead, you have this rapid, random, and chaotic signaling.
- 1:46This chaotic signaling leads to
- 1:48the ventricular walls spasming,
- 1:52and when the ventricular walls spasm,
- 1:54blood can't be circulated through the body.
- 1:57It just stays here in the heart.
- 1:59If you're not circulating blood to the rest of the body,
- 2:01you're depriving all of the other organs of oxygen.
- 2:05Another way to think about this is,
- 2:07think about if you were squeezing a tube of toothpaste.
- 2:11So, here you have a hand squeezing a tube of toothpaste,
- 2:14and you can imagine that if you squeeze
- 2:17with all your fingers at the same time,
- 2:20you're going to get the most toothpaste out.
- 2:24So, if you coordinate all your fingers
- 2:26to squeeze at the same time,
- 2:27you're going to squeeze out the most toothpaste,
- 2:29as opposed to if you squeezed your pinky
- 2:32and then your index finger and then your thumb,
- 2:35you're not going to squeeze out a bunch of toothpaste.
- 2:37This is the same idea as ventricular fibrillation.
- 2:39You lose this coordinated contraction
- 2:41and this coordinated squeeze
- 2:42to distribute blood to the rest of the body,
- 2:44and instead you have random firing of muscle cells,
- 2:46leading to this spasm,
- 2:48and you're not going to push out a lot of toothpaste
- 2:51or blood to the rest of the body.
- 2:53If V-fib isn't reversed immediately through electric shock,
- 2:56you're going to have permanent brain damage and death,
- 3:02because the brain and the body
- 3:03aren't getting enough oxygen.
- 3:05A person whose heart is in V-fib
- 3:08is not going to be conscious,
- 3:09since they have no blood circulating,
- 3:12and you won't be able to feel a pulse.
- 3:14Pulses are made by forward movement
- 3:17of blood to the vessels, so if you have no
- 3:19forward movement of blood to the vessels,
- 3:20you're not going to have a pulse.
- 3:22Sometimes, right before someone collapses
- 3:24from ventricular fibrillation,
- 3:25they might complain of signs or symptoms of a heart attack,
- 3:29like chest pain or numbness or tingling in their left arm,
- 3:33and that's because the heart is getting deprived of oxygen.
- 3:37Since the heart's not circulating blood
- 3:39to the rest of the body,
- 3:40it can't circulate blood to the heart itself,
- 3:43and since skin isn't getting oxygenated blood,
- 3:45you might see the skin turn pale or even a blue color.
- 3:51This is also known as cyanosis.
- 3:53That's the blue-color skin when you're not
- 3:55circulating oxygen through the body.
- 3:58An EKG in someone in V-fib looks like this.
- 4:01You're going to see course squiggly lines.
- 4:04This is because you lose this smooth signaling
- 4:07from the SA node to the AV node to the ventricles.
- 4:10Instead, in the ventricles you have this
- 4:12chaotic, erratic signaling,
- 4:14which looks like course squiggly lines on EKG.
- 4:17The ventricles are just spasming.
- 4:21Now, what are the big risk factors of V-fib?
- 4:24Well, I like to separate
- 4:25the major risk factors into two categories.
- 4:27The first one being anything that causes
- 4:30general irritability to the ventricular cells.
- 4:33Now, an irritable ventricular cell means
- 4:35that it's likely to just over-fire or fire abnormally.
- 4:42The other risk factors for V-fib is
- 4:44anything that causes scar tissue formation.
- 4:49Now, let's go back to the irritable ventricular cells.
- 4:51What would cause ventricular cells to be irritated?
- 4:54Well, the most classic example is coronary artery disease.
- 4:59Coronary arteries are the blood vessels
- 5:01that supply the heart with oxygenated blood,
- 5:04and over time these blood vessels can get clogged,
- 5:07and this might be because of years of smoking
- 5:09or bad diet, but over time these vessels get clogged.
- 5:14When the coronary arteries are clogged,
- 5:16you've got less blood flow to the ventricular cells.
- 5:19These cells get less oxygen than they're used to having,
- 5:22so they become irritated,
- 5:24and they're more likely to over-fire or fire abnormally.
- 5:28Also, certain electrolyte abnormalities,
- 5:31like high potassium or low calcium or low magnesium
- 5:36might cause ventricular cells to become irritable.
- 5:39And why is that?
- 5:41Well, electrolytes play an important role
- 5:43of normal electric conduction in the heart.
- 5:45And you can imagine if the electrolytes
- 5:47don't have the right levels,
- 5:49this could disrupt normal electric conduction
- 5:51through the heart.
- 5:53Okay, and now for scar tissue.
- 5:55So, we said scar tissue can also set up the heart
- 5:58for ventricular fibrillation.
- 5:59So, what might cause scar tissue?
- 6:01Well, the most classic example is a heart attack.
- 6:06Like we said, we have coronary arteries
- 6:08that supply the heart with oxygenated blood.
- 6:12When you have a heart attack,
- 6:14there is a coronary artery that gets clogged, totally,
- 6:18so no blood is getting to this part of the heart.
- 6:22So, whereas in coronary artery disease
- 6:25you had less blood flow,
- 6:27in heart attack you have no blood flow
- 6:30to this part of the heart, and this tissue ends up dying,
- 6:35and it's replaced by protein, kind of like a scab,
- 6:39and it creates this scar tissue.
- 6:41Now, scar tissue doesn't function like regular heart tissue.
- 6:45It's not going to conduct signal
- 6:48like regular heart tissue would.
- 6:49Instead, it sets up for abnormal firing
- 6:52or abnormal circuits in the heart.
- 6:55And this disruption in electrical conduction
- 6:57can set up the heart for ventricular fibrillation.
- 7:00Other things that can lead to scar tissue formation
- 7:03is a cardiomyopathy.
- 7:07So, cardiomyopathy just means disease of heart tissue,
- 7:10in which the heart tissue doesn't function as well.
- 7:14So, it loses function.
- 7:17It doesn't lose all function,
- 7:19but it doesn't function as well as a normal heart would.
- 7:22Cardiomyopathies have a lot of causes.
- 7:24So, infection can be a cause.
- 7:26So, there are some viruses that affect the heart
- 7:29and make the heart tissue actually decrease function.
- 7:33There are certain genetic disorders
- 7:36that can cause a cardiomyopathy,
- 7:40and these disorders will actually change the structure
- 7:43of the tissue of the heart, making them lose function,
- 7:47and also years of coronary artery disease,
- 7:49which I'm going to write as CAD,
- 7:52so, years of coronary artery disease,
- 7:54where the heart is constantly getting less oxygen
- 7:57than it optimally wants over years.
- 7:59Eventually, that heart tissue is going to lose function.
- 8:03Again, all of these things from the cardiomyopathies
- 8:05predispose the heart to have scar formation,
- 8:08and scar disrupts normal electrical conduction
- 8:12and can set the heart up for V-fib.
- 8:14And one final thing that might cause ventricular fibrillation
- 8:17that's not as common is electrocution.
- 8:22In electrocution, you have some sort of
- 8:24outside source of electricity entering the body.
- 8:27So, where the heart would have a normal
- 8:28electrical conduction system,
- 8:30electrocution is going to disrupt this normal signaling,
- 8:37and that can lead to ventricular fibrillation.
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