TRT VS Enclomiphene. It’s NOT even close! — Transcript
Full transcript
- 0:00If you're looking to raise your
- 0:00testosterone in 2026, TRT is no longer
- 0:03the only option. The closest thing we
- 0:06ever had to rival TRT was incl. And I've
- 0:08had thousands of men ask me if it's
- 0:10actually the smarter move. After all,
- 0:12it's a pill. It's way [music] more
- 0:13convenient, but it doesn't shut your
- 0:15natural production down either. Maybe it
- 0:17keeps your fertility fully impacted. So,
- 0:19it has to be better than TRT, right? As
- 0:21someone who's been on testosterone for
- 0:22the last 10 years and helping thousands
- 0:25of clients optimize their hormones, I
- 0:27can tell you [music] this debate isn't
- 0:28nearly as close as it looks. So, in this
- 0:30video, I'm going to break down exactly
- 0:32what a chopen is, how it's actually used
- 0:34in the real world protocols, and how it
- 0:36truly stacks up against the king of the
- 0:38hill, testosterone. Now, before we dive
- 0:40in, everything on this channel is for
- 0:41education entertainment purposes only.
- 0:43I'm not a medical doctor, so if you're
- 0:45going to start any of these treatments,
- 0:46do it under medical supervision, a
- 0:48licensed medical professional. Now we
- 0:50got that out of the way, let's dive in.
- 0:52To know exactly how inclinine helps
- 0:54increase your testosterone, you must
- 0:55understand how your body produces
- 0:57testosterone naturally in the first
- 0:58place. Because your testicles, I know,
- 1:00are actually the last stop in this whole
- 1:02chain of command. And that chain
- 1:04actually starts all the way up in your
- 1:05brain at the HPT axis, the hypothalamus.
- 1:09This is sitting all the way up top right
- 1:10here. It's constantly monitoring your
- 1:12hormone levels like a thermostat. When
- 1:14it senses your testosterone and estrogen
- 1:16are running low, it releases G&RH. G&R
- 1:19is a signal which goes straight to your
- 1:21pituitary gland. Your pituitary gets
- 1:23that signal and responds by releasing
- 1:25two hormones. You probably ever gotten
- 1:27blood work done over. LH, FSH, ever hear
- 1:29of it? LH travels down your testes and
- 1:32tells your latic cells to produce
- 1:33testosterone. FSH works alongside
- 1:36testosterone inside the testicles to
- 1:38keep the sperm production going and
- 1:40going. So the real chain looks just like
- 1:42this. Your brain senses low hormones.
- 1:45Your hypothalamus fires the G&R. Boom.
- 1:47pituitary fires, LH, FSH, boom, boom.
- 1:50Your testes now respond to them by
- 1:53producing testosterone and maintaining
- 1:55the sperm production. The whole system
- 1:56runs on this whole feedback loop. And
- 1:58the second your brain sees enough
- 2:00testosterone, estrogen circulating,
- 2:02pumps the brakes. It's the same logic as
- 2:04a thermostat shutting off when the heat
- 2:06in the room hits the right temperature.
- 2:08This feedback loop is exactly why TRT
- 2:10and Clomophane create two completely
- 2:12different outcomes in your body. Even
- 2:14though both of them raise your
- 2:15testosterone on paper, one of them works
- 2:17with the natural feedback, the natural
- 2:19loop, and the other one turns it off
- 2:21completely. The first one basically
- 2:23works with your body's natural feedback
- 2:25loop, which is inclenine
- 2:30citrate. Now, you probably know it by
- 2:32its brand name everyone here is Clomid.
- 2:34Now, Clomid was synthesized all the way
- 2:36back in 1956,
- 2:38555, somewhere around there. Wasn't even
- 2:40made for men. It was developed as a
- 2:42fertility drug for women. So I always
- 2:43hear like I'm putting on a women's drug.
- 2:45No, the FDA approved this in 1967 to
- 2:48help induce ovulation. To this day,
- 2:50that's still the only thing Clomid was
- 2:52actually FDA approved for. Clomid is
- 2:54actually a mix of two different
- 2:55isomeirs. Uh zucophene, which is the
- 2:57estrogenic half, and the other half is
- 3:00called uh inclin. Yeah, inclinestrogen
- 3:04half-life or a half of the drug. It's
- 3:05the one blocking those receptors and
- 3:08driving the LH and FSH to increase.
- 3:10Eventually, a company isolated pure
- 3:13enlomophene on its own and they tried to
- 3:15bring it to the market under the name
- 3:16Androxil. The trials look good on paper.
- 3:19It raised testosterone. It kept LHFSH in
- 3:22check, sperm production in check. But in
- 3:242015, the FDA, they rejected it because
- 3:27nobody could prove that raising the
- 3:29number actually made guys feel better.
- 3:30Now, inclane has never been approved as
- 3:32its own isolated drug. So, how is a drug
- 3:35that actually failed suddenly
- 3:37everywhere? [music]
- 3:38Two words, supply economics. When Clomid
- 3:41ran into supply shortages, prescribers
- 3:43pivoted right away and started
- 3:45compounding pure enclomophene
- 3:46immediately. And that's when the tele
- 3:48health companies noticed that
- 3:49enlomophene isn't a controlled
- 3:50substance. Testosterone [music] is,
- 3:52which means a tellahalth company can
- 3:54mail to a man in all 50 states almost
- 3:57none of the friction that comes with
- 3:59prescribing TRT. So, of course, it
- 4:01exploded. Not because it's the better
- 4:03tool for the [music] job, it's the
- 4:05easier one to prescribe. So, how does a
- 4:07clophen actually raise your tea levels?
- 4:08It goes straight to the top of the
- 4:10chain. Hypothalammus and pituitary.
- 4:12Remember that thermostat we talked about
- 4:13earlier with the that one constantly
- 4:16scanning your bloodstream
- 4:18for estrogen? So, it knows whether or
- 4:19not to keep producing or pump the
- 4:21brakes. And cholophene goes in and
- 4:23blocks the estrogen receptors sitting
- 4:25[music] at the thermostat. So, even
- 4:26though your estrogen is still
- 4:28circulating completely normal in your
- 4:29body, your brain can no longer see it.
- 4:32Now, as far as your hypothalamus goes,
- 4:34the room just went ice cold. Uh-oh. You
- 4:36know what that means, right? And a cold
- 4:38room means one thing. Turn up the heat,
- 4:40baby. So your hypothalammus panics a
- 4:42little bit and fires off more G and
- 4:44Rhoop,
- 4:46a lot more than normally would. And more
- 4:48G&RH means your pituitary responds by
- 4:51pumping out more LH and FSH. LH tells
- 4:54your latic cells to produce more
- 4:55testosterone. The FSH is going to keep
- 4:57your sperm production going all night
- 4:59long and the entire system is going to
- 5:01speed up now. So your body is still
- 5:03doing all the work and codophene is just
- 5:06convincing your brain that [music] it
- 5:08needs to work more and harder. That's
- 5:10exactly why guys chasing fertility or
- 5:13guys who aren't ready to use like TRT
- 5:14fully commit to that lifelong therapy,
- 5:16you know, they get pulled like a magnet
- 5:18towards this option. So if you're
- 5:19looking to test in Clomophane, this is
- 5:22the protocol I would definitely suggest
- 5:23that works for a lot of my clients. You
- 5:25want to start at 25 milligrams two to
- 5:28three times a week. [music] I mean
- 5:29that's great. Then you're going to
- 5:31assess your results after 45 to 60 days.
- 5:34On paper, this sounds like the smarter
- 5:35move. You start to raise your
- 5:37testosterone without shutting it down
- 5:38and that system that's actually
- 5:40controlling it and working it. But if
- 5:42reviving your engine harder was the
- 5:44superior right move, why does all the
- 5:47other side of this debate [music] exist
- 5:49at all? Then that's where testosterone
- 5:50comes in and it plays a completely
- 5:53different game. TRT is not going to ask
- 5:55for permission at all. It skips the
- 5:57entire chain that we just talked about
- 5:59and goes directly to the [music] end of
- 6:01the road, the finish line, whatever you
- 6:03want to call it. Extra testosterone
- 6:04injected straight into your bloodstream.
- 6:06It's there immediately at whatever level
- 6:08your protocol is dosed for or based on.
- 6:10Remember that thermostat before the
- 6:12enclomophane tricked into thinking that
- 6:14the room was actually cold? TRT does the
- 6:16exact opposite. Your brain sees
- 6:19testosterone flooding in to your
- 6:20bloodstream. As far as concerned, the
- 6:22room is [music] plenty warm. There's no
- 6:24reason to ask for more now. So, your
- 6:26hypothalammus stops firing G&RH. Your
- 6:28pituitary stops firing LH and FSH. And
- 6:31your testes get the signal to power
- 6:33down. Turn [music] right off, boys.
- 6:35Because the body doesn't waste energy on
- 6:36manufacturing something that's already
- 6:38getting [music] handed. This is why TRT
- 6:40by itself will shrink your testes and
- 6:42tank your natural sperm production over
- 6:44time, not immediately at all. Takes a
- 6:47long time to do that, if it ever
- 6:48happens, because your body has been told
- 6:50to clock [music] out and someone else is
- 6:52taking over. baby. And this the exact
- 6:54fork in the road that separates these
- 6:56two compounds. And once you understand
- 6:57that distinction, the entire which one
- 7:00is better, this whole debate stops. It
- 7:02stops being about which one actually
- 7:04raises your testosterone number because
- 7:05they both do that. What matters is which
- 7:08one actually delivers the final result
- 7:09that you want for performance. Is it
- 7:12body composition? Well, and how do you
- 7:14feel about taking testosterone? So,
- 7:15here's the problem that we have in
- 7:16chopene. Because here's what I've seen
- 7:18over the last 10 years on testosterone
- 7:20and helping thousands of clients with
- 7:23theirs. Remember, I was using
- 7:24testosterone all throughout my
- 7:25bodybuilding career since I was 15 16
- 7:28years old. And Clomophane moves your
- 7:30testosterone number on your labs on that
- 7:32piece of paper. But raising a number on
- 7:33a piece of paper, it's not the same. And
- 7:35actually feeling like a different man on
- 7:37those numbers is completely [music]
- 7:39different. The symptoms data on the
- 7:40enclophine is so weak. Clients report
- 7:43that they're told this climbs into an
- 7:44amazing range. Then they tell me that
- 7:46they [music] feel nothing or at best a
- 7:49little bit better, but they really don't
- 7:50know. The reason is that your body still
- 7:52relies on your own natural production to
- 7:54work with that number and carry that
- 7:56number. Which means every single
- 7:57variable that was tank your testosterone
- 8:00in the first place is still fully there.
- 8:02The stress, the no sleep, the diet, the
- 8:04training, none of that gets fixed just
- 8:06because you tricked your brain into
- 8:07producing more. [music] TRT doesn't have
- 8:10that problem. It bypasses all that and
- 8:12your dose isn't at the mercy of how well
- 8:15you slept last night or how well you ate
- 8:17yesterday. The second problem is the
- 8:19results from Mclomophene are not
- 8:21consistent from one guy to another. Two
- 8:23guys can walk into that room right now,
- 8:26get prescribed, have two identical labs,
- 8:29run the same exact dose of enlomophene,
- 8:31and one of them is going to feel
- 8:33incredible while the other one feels
- 8:35absolutely nothing. Now, some of that
- 8:37comes down to how your liver actually
- 8:38metabolizes it, which means you can't
- 8:40generally predict how your body is going
- 8:42to actually respond to you already spent
- 8:44months on this medication. TRT doesn't
- 8:47gamble like that with you. You dial in
- 8:48your dose and the results are reliable
- 8:5010 out of 10 times. The third problem is
- 8:53this one barely ever gets talked about
- 8:54and Clomophane has been shown to drop
- 8:57your IGF-1 levels in a very meaningful
- 8:59way. If your entire reason for chasing
- 9:01more testosterone is to build muscle and
- 9:03recover faster, tanking the hormone,
- 9:05well the downstream of this hormone of
- 9:07growth hormone, not a very smart move.
- 9:09And on top of that, and was never built
- 9:11or designed for the guy who was chasing
- 9:13performance. It was designed to protect
- 9:15fertility and make your labs look
- 9:17incredible. It is not going to help you
- 9:19build more muscle. It is not going to
- 9:20help you drop more body fat. It is not
- 9:22going to make you feel like the
- 9:23anti-aging effects are happening like
- 9:26you do on synthetic testosterone. So
- 9:28when you line up all these things, the
- 9:29inconsistent results, the weak symptom
- 9:31improvement, the no performance upside,
- 9:33possible IGF-1 getting hit, and zero
- 9:35long-term safety data against TRT, which
- 9:38bypasses every one of those variables
- 9:40and delivers an actual predictable,
- 9:42reliable result every single time, there
- 9:45is no version of this where include.
- 9:49TRT is still and will be the king of the
- 9:54hill. So now you know why there is no
- 9:56discussion about whether or not TRT is a
- 9:58better option. Let's talk about how you
- 10:00actually start. Because two objections
- 10:02always come up before a guy even starts
- 10:04TRT. The first one is always about
- 10:06fertility. If you start TRT and do
- 10:09nothing else, yes, [music] your natural
- 10:11production will shut down. Eventually,
- 10:13your sperm count will eventually drop
- 10:15with it. But that's not the full story
- 10:18though, because that's not how you
- 10:19properly run TRT and how the protocol
- 10:22should look like. If fertility matters
- 10:23to you, you pair TRT, your testosterone,
- 10:27with HCG because hGG mimics LH, which
- 10:31means it keeps knocking on your testes
- 10:33to [music] keep them turned on and keep
- 10:35your brain on to communicating with
- 10:37them. So, it keeps the signal on. Your
- 10:39testes have to stay active. So, the size
- 10:41needs to stay intact and your fertility
- 10:43is going to stay protected the entire
- 10:45time you're on testosterone. Any doctor
- 10:47that actually knows what he's doing in
- 10:49this space does [music] this for their
- 10:50patients day one. Now there are other
- 10:52options like HMG, FSH, Kiss Peptin,
- 10:55Gonarellin. Now there's also a lot of
- 10:57other lifestyle factors that determine
- 10:59how much of your fertility is going to
- 11:00take a hit. The guys who lose their
- 11:02fertility on TRT are the guys just
- 11:04[music] running it blindfolded. They're
- 11:06not running it with hCG. They're running
- 11:08it with no hg, [music] no blood work,
- 11:10and no one's there to help them. And
- 11:12even then, it takes a long time for you
- 11:14to run testosterone to completely shut
- 11:17down your fertility. I'm going to say it
- 11:18again. It takes a long time, if ever.
- 11:21But I've had hundreds, probably
- 11:23thousands at this point, clients
- 11:25restored their fertility and be able to
- 11:26conceive children. Even when it was
- 11:28zero, for months, I got them to be able
- 11:30to have kids. Even after full-blown
- 11:32steroid cycles or even on steroid
- 11:34cycles, you guys have no idea. It's
- 11:36going to be fine if you do this the
- 11:37right way. If you want the full protocol
- 11:39that I use to restore fertility, watch
- 11:41this video right here. It's absolutely
- 11:42amazing. You're going to learn so much
- 11:44about it. So, fertility isn't a reason
- 11:46to avoid TRT. Let's talk about the
- 11:48reason to make sure you're working with
- 11:49someone who actually knows what they're
- 11:51doing. Now, let's talk about the second
- 11:53objection, the stigma. Now, somewhere
- 11:55along the way, our society decided that
- 11:57a man optimized testosterone is the
- 11:59wrong move. You're the bad guy. But a
- 12:01guy walking around exhausted with man
- 12:03[music] boobs with no libido and
- 12:05drinking alcohol every weekend. Oh, that
- 12:07guy's just getting older. [music] And
- 12:08it's totally normal for our society
- 12:11here. Meanwhile, you've got A-list
- 12:13celebrities who are completely open
- 12:14about being on TRT. [music] They're all
- 12:16showing up jacked and leaner in their
- 12:1850s and no one cares. But the second the
- 12:20average guy says he's not on it, TRT.
- 12:22[music]
- 12:23Suddenly he's cheating. Cheating at
- 12:25what? What is he cheating at exactly?
- 12:27Because life is not a drug tested sport.
- 12:29There is no judge handing out medals for
- 12:32guys staying [music] natural. Nobody's
- 12:34checking your labs where they decide
- 12:36whether or not you get the promotion or
- 12:37if they want to be your friend. How
- 12:39about if you want to queue up your wife?
- 12:40How many of you actually want to be
- 12:41present [music] to be around your family
- 12:42and your kids? You're not competing
- 12:45against a field of guys who actually all
- 12:47agreed to play by the same rules. You're
- 12:49competing against guys in their 30s and
- 12:51up pretty optimized. They're already
- 12:53dialed in. They're already using every
- 12:55legal or illegal tool to available to
- 12:58them to actually operate at that level.
- 13:00So, if you're sitting on the sidelines
- 13:01refusing to use TRT [music]
- 13:03because you're worried about the society
- 13:05is going to judge you or they're going
- 13:07to have a stigma attached to you, you're
- 13:09just choosing to compete with one
- 13:11[music] hand tied behind your back
- 13:12against men who are not tying theirs.
- 13:15So, being natural is not a badge of
- 13:17honor for people, but they convinced you
- 13:19it was. It's just a version of you
- 13:21that's leaving [music] performance on
- 13:22the table for absolutely no reason. So,
- 13:25there you have it. complete breakdown on
- 13:27enlomophene [music]
- 13:28testosterone and why TRT is always going
- 13:31to be the superior option. If you're in
- 13:32your 30s, your 40s or 50s or older and
- 13:35you want to optimize your testosterone
- 13:36and completely transform your body
- 13:38working with someone who's done this
- 13:39with thousands of clients, click the
- 13:41first link in description to schedule a
- 13:43call. It's the first one. Do not miss
- 13:44it. If you got value from this video,
- 13:47make sure you subscribe, drop a comment.
- 13:49Thanks for watching. As always, [music]
- 13:50I'll see you on the next
About this transcript
This page contains the full transcript of TRT VS Enclomiphene. It’s NOT even close! by Nicholas Trigili | Human Performance Specialist, generated from the public captions YouTube serves with the video. The transcript has 2,759 words across 417 segments, with the original timestamps preserved so you can click any line to jump to that moment in the embedded player.
What you can do with it
Use the transcript to take notes, quote the speaker, build a study guide, generate a summary with ChatGPT or Claude via the YouTube Summary tool, or export it as a timed subtitle file with YouTube to SRT. You can also re-open it in the transcriber to translate the transcript into 100+ languages.
Free YouTube transcript tool
YouTube2Text is a free YouTube transcript generator — no signup, no daily limit. Paste any YouTube link and get the full transcript instantly, with timestamps, click-to-jump, translation to 100+ languages, AI prompts for ChatGPT, Claude, and Gemini, and exports to TXT, SRT, VTT, or Markdown.