THIS Is #1 FASTEST Way To BURN Fat Around Your Organs — Transcript
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- 0:00Dr. Rhonda Patrick, I am fascinated by
- 0:03so many of the things that you talked
- 0:04about and they're front of mind for me
- 0:05at the moment because I'm a 33-year-old
- 0:07man and I know from doing this podcast
- 0:10and looking at graphs like this one
- 0:12which we'll talk about today, which I
- 0:13don't think most people have ever seen
- 0:14in their lives, that this is the age
- 0:17where
- 0:19things might start changing direction
- 0:21from here on over the next decade and
- 0:23there's things I can do to set myself up
- 0:25now if I listen to your advice for the
- 0:28remaining decades of my life to be
- 0:29remarkably different. I'm playing with
- 0:31this in my hands at the moment. It's for
- 0:33anyone that can't see it, you should
- 0:34probably look at the screen right now.
- 0:35It's a yellow blob of squigy
- 0:41slightly disgusting
- 0:43material. What is this?
- 0:45And why does this matter?
- 0:47>> So this represents visceral fat.
- 0:51It's something that most people
- 0:54haven't heard of. Many people have heard
- 0:56of fat, they know fat is bad, but they
- 0:58don't realize there are different kinds
- 0:59of fat.
- 1:00>> Mhm.
- 1:00>> There [clears throat] is visceral fat
- 1:02and this is the kind of fat that you
- 1:04can't really pinch. Adipose tissue kind
- 1:06of fat, right? I mean, if you opened up
- 1:09your body, you could pinch it because
- 1:10it's deep, deep within your body. It's
- 1:13often referred to as belly fat.
- 1:15>> Mhm.
- 1:16>> And it's it's surrounding your organs
- 1:18like your liver, your kidney, you know,
- 1:20your intestines.
- 1:22This is a very deep belly fat. And it's
- 1:25very different from subcutaneous fat.
- 1:27You can actually be
- 1:29lean but have a high amount of visceral
- 1:32fat. We call these metabolically
- 1:33unhealthy people. So visceral fat, you
- 1:37mentioned you're 33,
- 1:39the average 33-year-old male has how
- 1:41much visceral fat?
- 1:43>> According to the data, it says roughly
- 1:451.2 lb at the age of 30 and then for a
- 1:48woman, 0.5 lb of visceral fat at the age
- 1:51of 30. At 40, it's 1.7 lb for a man and
- 1:560.7 lb for a woman at 50, 2.2 lbs for a
- 1:58man, 1 lb for a woman, and at 60, 2.7
- 2:02lbs of visceral fat, and 1.54 lbs for a
- 2:07woman, which is the highest risk for
- 2:09metabolic syndromes at that age. But, I
- 2:11mean, all of them are pretty scary.
- 2:12>> It is. And as you notice, the trend is
- 2:14as you get older, you have a higher risk
- 2:16of having more of it.
- 2:1870% of women over the age of 50 have a
- 2:20high amount of visceral fat. 50% of men
- 2:22over the age of 50 have a high amount of
- 2:24visceral fat.
- 2:25This visceral fat, for one, it's going
- 2:27to double your risk of early mortality.
- 2:30Full stop. That's That's, you know, it's
- 2:32it's going to double your risk.
- 2:33>> Double your risk.
- 2:34>> Double. Double. Visceral fat is, as I
- 2:37mentioned, different from the other kind
- 2:39of fat, the subcutaneous kind of fat,
- 2:41the adipose tissue kind of fat,
- 2:43in several ways. One is that it is
- 2:47metabolically active.
- 2:49It is secreting inflammatory cytokines.
- 2:52These are,
- 2:53you know, molecules that are signaling
- 2:56to the immune system, but they're also
- 2:57involved with damaging our cells. And
- 3:01for this reason, people with a high
- 3:03amount of visceral fat are 44% more
- 3:05likely to get metastatic cancer. That's
- 3:08cancer that's going to metastasize. Very
- 3:11dangerous types of cancer. They're also
- 3:13more likely, you mentioned metabolic
- 3:14syndrome. This is a big big thing with
- 3:16visceral fat.
- 3:18This type of fat is constantly
- 3:22breaking down triglycerides into free
- 3:24fatty acids. It's constantly doing it.
- 3:27>> What's triglycerides?
- 3:28>> Triglycerides are how your body is able
- 3:31to store fatty acids and fat and use
- 3:35them for later, you know, energy, right?
- 3:37So, they're constantly breaking them
- 3:39down and using them. They're using these
- 3:40these fatty acids. But, typically what
- 3:42happens in your body
- 3:44when you eat a meal,
- 3:46you have your glucose levels go up,
- 3:48right? Your blood sugar elevates, your
- 3:49glucose levels go up, and that signals
- 3:51to the pancreas in your body to make
- 3:53insulin. Insulin is this hormone that
- 3:56plays a role in many things. One of it
- 3:57is to tell different parts of the body
- 3:59to take glucose glucose up, like your
- 4:01liver, your muscle, your adipose tissue.
- 4:03Well, the problem is is this visceral
- 4:05fat is constantly making those free
- 4:07fatty acids, and so those fatty acids it
- 4:10doesn't it doesn't respond this this we
- 4:13call it it's not really an organ, but
- 4:15this type of fat doesn't respond to
- 4:17insulin. So, whereas the subcutaneous
- 4:19fat will stop
- 4:21breaking down fat and using fat as
- 4:22energy. It says, "Okay, look, I have
- 4:24energy here. I got to do something with
- 4:26this energy. Let me let me store it for
- 4:28later use, right?"
- 4:30Well, that that doesn't happen with
- 4:31visceral fat. What happens is it just
- 4:33keeps going, keeps going, keeps going.
- 4:35What happens is when your visceral fat
- 4:38is metabolically active like that, it is
- 4:40basically making it where insulin can't
- 4:43work its job. And so, what happens is
- 4:47that glucose can't go into your liver.
- 4:50It stays in your blood system.
- 4:51>> And you really want it to be stored in
- 4:52your liver, right?
- 4:53>> You want it to be stored in your liver
- 4:54as glycogen to be used as energy when
- 4:56you're fasting or when you're, you know,
- 4:58physically active or when I whenever you
- 4:59need it, right? Also in your muscle,
- 5:01same thing, stored as glycogen or stored
- 5:03in your adipose tissue. Um and so and so
- 5:06none of that happens because insulin
- 5:08it's not able to to basically act on
- 5:11your your your organs. It there's no
- 5:13signal. So, no nobody's getting the
- 5:15phone call, "Hey, time to take the
- 5:16glucose up." It's not happening, right?
- 5:18So, the glucose sits around. So, what
- 5:20happens is your body freaks out because
- 5:22it's not good to have glucose sitting
- 5:24around in your bloodstream for a while.
- 5:26It causes a lot of damage, right?
- 5:27>> Mhm.
- 5:28>> And [clears throat] so, what happens is
- 5:28your body makes even more insulin to try
- 5:31to overcompensate. Your body goes, "Oh,
- 5:33maybe that wasn't enough insulin
- 5:35because, you know, the glucose isn't
- 5:36coming in to the organs like the liver
- 5:38like it's supposed to. So, let me put
- 5:40some more out."
- 5:41>> And for anyone that doesn't know,
- 5:42insulin is kind of like the taxi driver
- 5:44that goes and picks up the glucose and
- 5:45takes it home.
- 5:46>> Right, exactly. It's taking it home.
- 5:48It's taking it back to the liver. And
- 5:49so, what happens when you make more
- 5:51insulin, you're overcompensating in such
- 5:53a way that now glucose really does get
- 5:56taken up into these other organs like
- 5:58the liver.
- 5:59And it so much so that it causes your
- 6:03blood glucose levels to go down and and
- 6:05you're crashing. And all of a sudden,
- 6:07this is responsible for that
- 6:09you know, people that eat a meal and
- 6:11they're kind of insulin resistant, they
- 6:13eat a meal and then all of a sudden
- 6:15they're crashing an hour later. We're
- 6:16like, why am I why do I have no energy?
- 6:19Why am I hungry? Right? Because when
- 6:21you're after you crash, your your blood
- 6:23glucose levels go down. That's what I
- 6:24mean by crashing. Um really far far
- 6:27down, not not normal levels, but like
- 6:29below that. And so, then your body
- 6:31should tries to overcompensate by going,
- 6:33"Oh, I'm hungry. I need to eat." And so,
- 6:35you start to have these cravings for
- 6:36like energy dense foods. And that's part
- 6:39of this cycle of the beginnings of
- 6:41insulin resistance. And so, what I'm
- 6:43talking about here with visceral fat, it
- 6:45causes insulin resistance. And that's
- 6:47essentially the take home here. By by
- 6:49its constantly metabolizing fatty acids,
- 6:52it's it's stopping that taxi car from
- 6:54going and getting the glucose. It's It's
- 6:56not happening. It's not responding.
- 6:58You're not picking up the driver, right?
- 7:00And so, you become insulin resistant.
- 7:02And that has a lot of problems. One,
- 7:04it's going to affect your immediate
- 7:06energy levels. It's going to affect the
- 7:07way you're feeling. And two, it's going
- 7:10to make you more likely to become type 2
- 7:13diabetic. Cuz eventually, your body will
- 7:16won't be able to produce enough insulin
- 7:18to bring the glucose in. And so, then
- 7:19you become type 2 diabetic. So, that is
- 7:22a big consequence of having this
- 7:24visceral fat in addition to those
- 7:26inflammatory molecules that are being
- 7:28generated from this fat. It's just so
- 7:30metabolically active. And that
- 7:32inflammation that you're generating not
- 7:34only does things like raise your cancer
- 7:35risk by 44%, it also makes you tired. It
- 7:40gives you
- 7:41brain fog, lethargy. When your immune
- 7:44system is being activated by this
- 7:45inflammation,
- 7:47you're taking energy away from your
- 7:48brain. It It's a lot of energy to
- 7:51activate your immune system. And so
- 7:53Yeah, so that energy is now going to the
- 7:55wrong place. It's not going to your
- 7:57brain.
- 7:57>> So you can feel You won't feel
- 7:58cognitively as sharp and
- 8:00>> Absolutely [clears throat] won't. Just
- 8:01think about when you're when you're when
- 8:02you have an infection. Your immune
- 8:04system is very active. You're fighting
- 8:05off a pathogen, right?
- 8:07Do you feel like you're tired or do you
- 8:08feel like you're cognity cognitively at
- 8:11your
- 8:11>> Oh, yeah. I'm like I'm I'm out of out of
- 8:13action for several days usually.
- 8:14>> Right. You're tired and your brain isn't
- 8:16working. And part of that reason is
- 8:17because your activation of your immune
- 8:19system is sucking energy away from your
- 8:21brain. And the other reason is because
- 8:23the inflammation being generated gets
- 8:25into the brain and disrupts
- 8:27neurotransmitters and things like that.
- 8:28So you're It's like a double whammy.
- 8:30You're not Your your brain isn't working
- 8:32working properly. And so there's a lot
- 8:33of people walking around constantly
- 8:36feeling tired, feeling lethargic,
- 8:38feeling brain fog. And they might have a
- 8:40high amount of visceral fat and not even
- 8:42know it. So typically
- 8:45>> Looking at the data, I mean most people
- 8:46have too much visceral fat.
- 8:48>> Most people do have too much visceral
- 8:49fat. And typically a really high amount
- 8:52is
- 8:53I would say a proxy for it would be
- 8:55measuring your waist circumference. So
- 8:57like if women have a waist circumference
- 8:59of 35 in
- 9:00or greater, that is a sign of too much
- 9:02visceral fat. If men have a waist
- 9:05circumference of 40 in or more, that is
- 9:07a sign of too much visceral fat. Ideally
- 9:09you would go and get what's called a
- 9:10DEXA scan. Now this is not something
- 9:12that's routinely done and it doesn't
- 9:14necessarily have to be done unless
- 9:16you're that person that really likes to
- 9:17go the extra mile and directly measure
- 9:19things. That [clears throat] would be
- 9:20another way to do it. You really want to
- 9:22have below 300, you know, grams of
- 9:24visceral fat. Ideally closer to zero the
- 9:26better.
- 9:27>> Me and my friend went and got a DEXA
- 9:28scan done. And the remarkable thing is I
- 9:32weigh a lot more than him and I'm much
- 9:33bigger than him. He's skinny.
- 9:36But after the DEXA scan, they said that
- 9:38he had too much visceral fat.
- 9:40Which I thought this I thought you must
- 9:41be like big or a beast to have visceral
- 9:43fat, but he's a skinny guy, and the DEXA
- 9:46scan said too much visceral fat.
- 9:48>> Yes, that's the thing. You know, I was
- 9:50involved in clinical research for many
- 9:52years when I was doing my postgraduate
- 9:53training, and we were looking at
- 9:56populations of people that were
- 9:57metabolically unhealthy, maybe
- 9:59overweight, obese in some cases, and you
- 10:02would have someone come in that they
- 10:04looked skinny. They looked like they
- 10:06were metabolically healthy because they
- 10:07weren't overweight, and yet
- 10:10all of their biomarker data was showing
- 10:11the opposite. Like you they looked on
- 10:13paper, if you would have shown me their
- 10:15metabolic data, I would go, "Oh, this is
- 10:16an overweight obese person." So, these
- 10:18are these are lean but metabolically
- 10:20unhealthy people, and a large percentage
- 10:21of that has to do with an increase in
- 10:23visceral fat. You won't even necessarily
- 10:25know that you're getting higher amounts
- 10:27of visceral fat. It's not necessarily
- 10:29going to be reflected on the scale. You
- 10:31know, you mentioned maybe a pound, maybe
- 10:32a little bit more. That's like daily
- 10:34fluctuation in some cases, right? Like I
- 10:36mean, I don't know about you, but like I
- 10:38I can fluctuate a pound from day to day,
- 10:40for sure. If you're talking about 500 g
- 10:43or less, that's not going to be, you
- 10:44know, reflected on the scale, either.
- 10:46You might be going, "Well, what
- 10:48why visceral fat? What's causing
- 10:50visceral fat?" You know, I mentioned
- 10:51age, that's a big one. Hormones is a big
- 10:54one. Women are very susceptible as they
- 10:56go through perimenopause and menopause
- 10:58because estrogen actually tells helps
- 11:01tell the body how to store energy, and
- 11:04it tells it to store energy in fat in
- 11:07adipose tissue, not viscerally. So, when
- 11:09your estrogen starts to go down during
- 11:11perimenopause and then menopause,
- 11:14women really start to gain a lot of this
- 11:16this belly fat. They gain a lot of the
- 11:17visceral fat. Testosterone also, it
- 11:20doesn't tell the body how to store the
- 11:22fat so much, it helps you burn visceral
- 11:24fat. So, men are a little bit more
- 11:26protected when they're younger, as well,
- 11:28but as they age, of course, testosterone
- 11:30goes down, as well, and that affects the
- 11:31visceral fat. But mostly, it's our diet
- 11:34and our lifestyle that's really
- 11:35affecting visceral fat. It's kind of
- 11:38mind-blowing how quickly you can gain
- 11:40visceral fat. Like
- 11:42there was sleep is a big one. When
- 11:44you're When you miss sleep, that is
- 11:46something that can really you can start
- 11:48to store You can start to gain visceral
- 11:50fat very quickly. Um there was a study
- 11:52in healthy young men. These men were
- 11:55sleep restricted. Typically, when sleep
- 11:57restriction studies are done, you're
- 11:58you're looking at 4 hours of sleep per
- 12:00night. So, pretty severe. Not out of the
- 12:03ordinary. I did many of those college,
- 12:05graduate school, deadlines. Definitely
- 12:07as a new parent. I mean, it's
- 12:08unfortunately drags on for months. So,
- 12:11these men were only sleeping 4 hours a
- 12:12night for 2 weeks. Okay, these were
- 12:15healthy young men, college-age students.
- 12:16Okay, young.
- 12:18They gained 11% visceral fat after that
- 12:212 weeks, but not a pound on the scale.
- 12:23But they had 11% higher visceral fat
- 12:26after just
- 12:28you know, 2 weeks of not getting enough
- 12:29sleep.
- 12:30>> And they weighed the same.
- 12:31>> Pretty much.
- 12:32>> it was the composition of their body
- 12:34that's shifting.
- 12:34>> Yes. Also, the visceral fat, like like I
- 12:37said, you're not gaining pounds and
- 12:38pounds and pounds of it necessarily. You
- 12:40know, you're you're gaining grams and
- 12:42grams, but like it's happening. And And
- 12:44any amount that you're starting to gain
- 12:46is unhealthy, right? It's going to start
- 12:48causing insulin resistance. It's going
- 12:49to start, you know, causing fatty liver.
- 12:51That's another thing it does it cuz it's
- 12:52around the liver. It basically the liver
- 12:54doesn't know what to do with all the
- 12:55fat, so it starts to make and store it
- 12:57around the fat. And so, you start to get
- 12:59this nonalcoholic fatty liver, which is
- 13:00happening now in like young people.
- 13:03So, sleep is one. Another major, major,
- 13:05I would say, lever for gaining visceral
- 13:07fat is your diet.
- 13:09Quality and quantity.
- 13:11So, if you start to be in a caloric
- 13:14excess constantly, you can start to gain
- 13:17visceral fat. And that's also been shown
- 13:18in studies. So, there was a recent study
- 13:21that again was in healthy young men
- 13:23given about 1,200 extra calories a day.
- 13:26And it was mostly from ultra-processed
- 13:29foods, right? I mean, they're 1,200
- 13:31calories, so like
- 13:32Big Mac and a Coke. Big Mac and fries,
- 13:35whatever, you know. So, you're you're
- 13:36talking about almost like an extra meal
- 13:38a day.
- 13:39And from processed foods,
- 13:41ultra-processed foods, for 5 days, they
- 13:44were given, you know, this extra caloric
- 13:46intake. After that 5 days,
- 13:48they started to gain visceral fat, they
- 13:50started to have signs of fatty liver
- 13:52after 5 days, and their brains became
- 13:54insulin-resistant. And this is
- 13:56important. Yes, you
- 13:58>> So, how many calories were they having
- 14:00in excess?
- 14:01>> 1,200 to 1,500.
- 14:02>> In excess?
- 14:03>> More than what they were usually going
- 14:06to eat, yes.
- 14:07>> Okay.
- 14:07>> Yes. So, you know, it's a lot of people
- 14:10are eating caloric excess, you know,
- 14:14daily. They're not They're not
- 14:16exercising, and there's no energy
- 14:17expenditure, and they're eating more.
- 14:19And so, they're in in, you know, 1,200.
- 14:22Now, this is the extreme end, right?
- 14:24I'm giving you the extreme end cuz
- 14:25that's what they do usually in in
- 14:26studies like this because they want to
- 14:27get a significant result. But after 5
- 14:30days, they they were gaining a visceral
- 14:33fat, their brains became
- 14:34insulin-resistant. So, insulin is also
- 14:36very important for the brain. The brain
- 14:38is telling the body how to store the fat
- 14:40and how to store energy.
- 14:42And when the And when insulin's not able
- 14:43to to get into the brain and have its
- 14:45action, then you start to not have the
- 14:48brain tell the body how to store this
- 14:50energy, and it ends up storing it
- 14:51viscerally. It's like this default.
- 14:54>> Do you know, putting those two things
- 14:54together, the thing I've noticed that
- 14:56impacts my performance the most as it
- 14:58relates to articulation, cognitive
- 15:00performance, my ability to think, is
- 15:02those two things coming together. You
- 15:04talked about sleep and diet. It's when I
- 15:06have I eat late.
- 15:09>> Mhm.
- 15:09>> Close It's when I eat close to sleep. If
- 15:12I do that a couple of nights in a row,
- 15:14I feel like my brain no longer works.
- 15:16>> Yes, yeah. You know, obviously, we all
- 15:18have to like live our lives, and there's
- 15:19social things, and it's fun to go out
- 15:21and have a dinner with your friends or
- 15:22an event, right? But,
- 15:25it's not a good idea to eat a meal,
- 15:28a big meal, three at three hours before
- 15:32fewer than three hours before bed. So,
- 15:33you want to stop eating three hours
- 15:34before bed. And three is really the
- 15:36magic number in multiple studies because
- 15:39when you eat a meal, it is activating
- 15:42your sympathetic nervous system,
- 15:44right? That's the fight or flight
- 15:46response.
- 15:48That's not what you want active when
- 15:49you're about to go to bed. When
- 15:51activating the sympathetic nervous
- 15:52system right before you're going to bed,
- 15:53let's say you eat a meal within an hour
- 15:56of bedtime,
- 15:57you're digesting all that. It's your
- 15:58sympathetic nervous system's active. And
- 16:00even if you're sleeping,
- 16:02it's [snorts] not good sleep. It's
- 16:04fragmented sleep. And so, it's disrupted
- 16:07sleep because you you need to be in that
- 16:09parasympathetic
- 16:11part of, you know, the nervous system,
- 16:13that dominance needs to be
- 16:14parasympathetic, which is the res- rest,
- 16:17restore. It's called rest and digest.
- 16:20But, I don't like digest because
- 16:21actually digesting is what activates the
- 16:23sympathetic nervous system. So, it's
- 16:24like the recovery, right?
- 16:26>> So, should I stay up then for three
- 16:27hours? If I If I eat at midnight,
- 16:30should I stay up till 3:00 a.m.?
- 16:32>> No. No, you should just go to bed, but
- 16:34don't do it on a daily basis, right? I
- 16:36mean, the the key is the habit, you
- 16:39know, the habit. And so,
- 16:40if you need to eat something before bed,
- 16:42you should do something that's light,
- 16:44maybe a protein shake with some almond
- 16:46milk, you know, something that's not
- 16:48super heavy.
- 16:49>> I've heard you talk about fiber.
- 16:51>> Resistant starch does it interestingly
- 16:54seem to help improve sleep. And so, you
- 16:57know, maybe some rice or a potato, a
- 16:59little bit of rice or a potato.
- 17:01>> or something.
- 17:01>> [laughter]
- 17:02>> Maybe not a fried potato.
- 17:04Baked baked potato and then cool it cuz
- 17:06then it's resistant starch, right? Cuz
- 17:07then it's good for your your gut
- 17:09microbiome.
- 17:10>> Why?
- 17:11>> It changes the composition of the fiber.
- 17:14>> Mhm.
- 17:14>> And [clears throat] and you can cook it,
- 17:16let it cool, and then heat it again if
- 17:18you like to eat it heated as long as it
- 17:19went through a cooling part. Well, and
- 17:21then you can eat it. But, that's
- 17:22resistant starch. Resistant starch is
- 17:24also in green bananas. Very beneficial
- 17:26for the gut and also for interestingly
- 17:29for improving sleep. So, things that are
- 17:31really moving the needle to to make you
- 17:34gain visceral fat or being basically
- 17:36being in a caloric excess, especially
- 17:38from refined high-fat, high-sugar foods.
- 17:41And then not getting enough sleep move
- 17:44the needle. Chronic stress is an
- 17:46amplifier of it. So, if you're
- 17:48constantly having cortisol, that's kind
- 17:51of stopping the body from storing energy
- 17:53right the right way and it's going
- 17:54viscerally as well. I would say that
- 17:56amplifies, especially if it's like in
- 17:58the context of being in a caloric excess
- 18:00and not exercising. Alcohol is another
- 18:03one. If you drink If you're excessively
- 18:04consuming alcohol, you're going to store
- 18:07a lot of the energy that you're also
- 18:08consuming is going to be stored
- 18:09viscerally. I mean, you've seen the beer
- 18:10belly, right? I mean, that's like a
- 18:11thing. It's visceral fat. It's It's not
- 18:14beer. It's visceral fat. So, alcohol is
- 18:17another one.
- 18:18In terms of losing visceral fat, I mean,
- 18:20the good news is is that you can lose it
- 18:23quite easily and quite rapidly.
- 18:25>> I was going to say parents have a hard
- 18:26time because you're [clears throat]
- 18:27naming those things about like sleep and
- 18:30stress. And And I was thinking, gosh,
- 18:32parents have like a have it coming from
- 18:33them from all sides.
- 18:35>> They do. Um the But, see, this is where
- 18:37the good news comes in because, you
- 18:39know, part of the reason why sleep is
- 18:42causing you to gain more visceral sleep
- 18:44loss is causing you to gain visceral fat
- 18:47is because it's causing your body to
- 18:48become insulin resistant. It's like this
- 18:50vicious cycle. Visceral fat causes
- 18:52insulin resistance. Insulin resistance
- 18:55causes more visceral fat.
- 18:56>> If you love the Diary of a CEO brand and
- 18:58you watch this channel, please do me a
- 18:59huge favor. Become part of the 15% of
- 19:03the viewers on this channel that have
- 19:04hit the subscribe button. It helps us
- 19:06tremendously, and the bigger the channel
- 19:07gets, the bigger the guests.
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