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The World’s No.1 Sleep Expert: The 6 Sleep Hacks You NEED! Matthew Walker — Transcript

by The Diary Of A CEO · 22,116 words · 3,515 segments · language en · Watch on YouTube

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  1. 0:00When you're struggling with sleep in the
  2. 0:01middle of the night, and you're wide
  3. 0:02awake in the last hour before bed, try
  4. 0:05this experiment.
  5. 0:08I'm I'm sold.
  6. 0:10Matthew Walker.
  7. 0:11Neuroscientist and best-selling author.
  8. 0:13And one of the world's leading
  9. 0:14researchers in sleep science. It's going
  10. 0:17to blow your mind.
  11. 0:18There's a global sleep loss epidemic
  12. 0:20shaped by this thing called the modern
  13. 0:22world. What society wants is that you're
  14. 0:24either producing or you're consuming. In
  15. 0:26fact, the CEO of Netflix is stating was
  16. 0:30that we ought to commit war against
  17. 0:31sleep. We have this mentality in
  18. 0:34business. Less sleep equals more
  19. 0:36productivity. That is just not true.
  20. 0:38Insufficient sleep costs most nations
  21. 0:41about $411 billion.
  22. 0:44Jeez.
  23. 0:45Your rates of obesity, cardiovascular
  24. 0:47disease, mental health conditions, all
  25. 0:49of these things escalate. If that wasn't
  26. 0:51bad enough,
  27. 0:51Oh my god.
  28. 0:52if you're not getting sufficient sleep,
  29. 0:54then 60% of all of the weight that you
  30. 0:58lose will come from lean muscle mass and
  31. 1:01not fat.
  32. 1:03Not the muscle. How would you redesign
  33. 1:05society to help us to sleep better?
  34. 1:07So, first I would
  35. 1:10Feels like caffeine is a miracle drug
  36. 1:12with no apparent cost. Was I wrong or
  37. 1:14was I right?
  38. 1:16Wrong. Caffeine will hurt your sleep in
  39. 1:18three ways most people are not aware of.
  40. 1:21So, if you have a cup of coffee at
  41. 1:23midday, what happens is that
  42. 1:28Before we get into this episode, just
  43. 1:29wanted to say thank you first and
  44. 1:31foremost for being part of this
  45. 1:32community. Um the team here at The Diary
  46. 1:34of a CEO is now almost 30 people, and
  47. 1:36that's literally because you watch and
  48. 1:38you subscribe and you um leave comments
  49. 1:40and you like the videos that that this
  50. 1:42show's been able to grow. And it's the
  51. 1:44greatest honor of my life to sit here
  52. 1:45with these incredible people and just
  53. 1:47selfishly ask them questions that I'm
  54. 1:49pondering over or worrying about in my
  55. 1:50life. But this is just the beginning for
  56. 1:52The Diary of a CEO. We've got big big
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  69. 2:15Means the world.
  70. 2:17Let's get on with it.
  71. 2:25Matt,
  72. 2:26I have spent the longest time trying to
  73. 2:29sit down with you on this podcast. So,
  74. 2:31I'm very very happy to spend some time
  75. 2:33with you today.
  76. 2:35And that is because your your work is
  77. 2:37now world-renowned um and it's very very
  78. 2:40important work.
  79. 2:41But,
  80. 2:43as is the case with a few of the recent
  81. 2:44episodes in this podcast, I wanted to
  82. 2:46start by asking you,
  83. 2:48in your view,
  84. 2:50what is it you do and why is it so
  85. 2:52important in your mind that you do it?
  86. 2:56Well, firstly, thank you so much for
  87. 2:58having me here and having this
  88. 3:00conversation. It's an incredible
  89. 3:02privilege to sit with you.
  90. 3:04Um
  91. 3:05why do I do what I do and why do I think
  92. 3:08it's important?
  93. 3:09Um
  94. 3:10sleep, I would argue, is the single most
  95. 3:14effective thing that you can do to reset
  96. 3:16your brain and body health.
  97. 3:19And I don't say that flippantly. It's
  98. 3:20not as though I'm dismissing exercise or
  99. 3:23diet. Those two things are absolutely
  100. 3:25critical.
  101. 3:27But, if I were to take you, the
  102. 3:28individual, and deprive you of exercise
  103. 3:31for a day, deprive you of food for a
  104. 3:34day, deprive you of water for a day, or
  105. 3:36deprive you of sleep for a day, 24
  106. 3:39hours, and I were to map your brain and
  107. 3:42body impairments, it's not even a
  108. 3:44competition.
  109. 3:45That one night of lost sleep relative to
  110. 3:47those other things, it dwarfs The only
  111. 3:50thing I lose out against is oxygen. If I
  112. 3:53deprive you oxygen, you're going to pop
  113. 3:55out
  114. 3:56of existence a little bit quicker than
  115. 3:57you will with a lack of sleep. So,
  116. 4:00sleep to me, I think, is the elixir of
  117. 4:04life. It is your life support system.
  118. 4:07And as best we can tell, I would argue
  119. 4:09it's Mother Nature's best effort yet at
  120. 4:12immortality.
  121. 4:14And so in that regard, that's why I when
  122. 4:16I look across all of the studies and all
  123. 4:18of the data, it's so compelling to me.
  124. 4:21And part of the reason I think it's I've
  125. 4:24desperately tried and I haven't done a
  126. 4:26good job, but I've tried to offer some
  127. 4:29public mission of reuniting humanity
  128. 4:31with the sleep that it's so bereft of is
  129. 4:34because it does appear that there is a
  130. 4:36global sleep loss epidemic. If you look
  131. 4:38at the numbers, people are struggling so
  132. 4:41desperately with their sleep. So we have
  133. 4:44all of this knowledge, this incredible
  134. 4:45knowledge of sleep and how important it
  135. 4:47is.
  136. 4:48And it's a perfect storm colliding with
  137. 4:50this great sleep depression in modern
  138. 4:53society. And for that reason, I just
  139. 4:56felt as though what can I do to try to
  140. 4:58help, offer this voice and this science.
  141. 5:02And I am but a scientist and I stand on
  142. 5:05the shoulders of all of my colleagues
  143. 5:07and all of these giants in the field.
  144. 5:08I'm just a researcher, so that's a
  145. 5:10little bit about I guess who I am, but
  146. 5:13more about why I do it and why I think
  147. 5:15it's important.
  148. 5:16If I were to try and define your sort of
  149. 5:18And this I hate doing this because it
  150. 5:19requires the application of some kind of
  151. 5:21narrow label. If I was to try and define
  152. 5:23what your title is in your own words,
  153. 5:26what would that be?
  154. 5:27So I'm just a professor of neuroscience,
  155. 5:30of brain science at the University of
  156. 5:31California, Berkeley.
  157. 5:33Um I am I am not a medical doctor, just
  158. 5:36FYI for all of the things that we will
  159. 5:38talk about in this conversation. Uh so
  160. 5:40I'm just a PhD.
  161. 5:42Just a PhD.
  162. 5:43Yeah.
  163. 5:44You know, that's um
  164. 5:45incredibly humble of you, but but I
  165. 5:47would assert that you're without a
  166. 5:49shadow of a doubt the leading
  167. 5:52author, scientist, commentator, voice as
  168. 5:57it relates to the topic of sleep.
  169. 5:59And my my my question from that is,
  170. 6:02where did that begin? Like, where did
  171. 6:04that start in your life, in the journey
  172. 6:06of your life? When did sleep become the
  173. 6:09thing?
  174. 6:11It occurred to me or happened to me, I
  175. 6:14should say, when I was doing my PhD. I
  176. 6:16was studying people with dementia and we
  177. 6:19were trying to understand what type of
  178. 6:22different dementia that they had very
  179. 6:24early on in the course of the disease.
  180. 6:27And we were looking at patterns of brain
  181. 6:29wave activity. So, I was placing
  182. 6:30electrodes all over the head and I was
  183. 6:32measuring them and I was trying to
  184. 6:34differentially diagnose them very early
  185. 6:36on and I was getting no good data
  186. 6:39whatsoever. I was miserable. Nothing was
  187. 6:41was landing.
  188. 6:43And one day I went home uh at the
  189. 6:45weekend and sort of with all of my
  190. 6:47printed journals and I go to the my
  191. 6:49doctor's residence and have this sort of
  192. 6:51eggloo of journals around me that I
  193. 6:53would sit and read at the weekend. Um,
  194. 6:56and I was which probably tells you
  195. 6:57everything about my social life at the
  196. 6:59weekend if that's what I was doing, but
  197. 7:01um so I was reading these journals and
  198. 7:04it occurred to me that some of these
  199. 7:05dementias were eating away at the sleep
  200. 7:07centers in the brain and others would
  201. 7:09leave them untouched. And at that moment
  202. 7:12I realized I'm measuring my patients at
  203. 7:14the wrong time. I'm measuring them when
  204. 7:16they're awake. Should be measuring them
  205. 7:19when they're asleep.
  206. 7:20Started doing that, got amazing results.
  207. 7:23And at that point I wanted to ask the
  208. 7:25question, well, I wonder if the sleep
  209. 7:28problems are not simply a symptom of the
  210. 7:31dementia.
  211. 7:32I wonder if it's a potential cause of
  212. 7:35the dementia.
  213. 7:37And at that point I started to think,
  214. 7:38well, so then what is this thing called
  215. 7:40sleep?
  216. 7:42And what I learned is that some of the
  217. 7:45greatest minds in the past 100 years had
  218. 7:48tried to answer a very simple question.
  219. 7:51Why do we sleep?
  220. 7:53And you know, 30 years ago in fact, the
  221. 7:56crass answer was that we sleep to cure
  222. 7:59sleepiness.
  223. 8:02Which tells you nothing about you know,
  224. 8:03it's like saying, I eat to cure hunger.
  225. 8:05Well, no, you that's not the right
  226. 8:08answer.
  227. 8:09Now, 30 years later, we've had to upend
  228. 8:12the question and we now have to ask, is
  229. 8:15there any physiological system in your
  230. 8:17body? Is there any operation of your
  231. 8:19mind that isn't wonderfully enhanced
  232. 8:22when you get sleep or demonstrably
  233. 8:24impaired when you don't get enough?
  234. 8:26And the answer seems to be to be no
  235. 8:28there. So, my journey into the science
  236. 8:32of sleep really was an accident. But at
  237. 8:34that moment in time when I started
  238. 8:36reading about sleep, I utterly fell in
  239. 8:39love with the topic.
  240. 8:41And it is a love affair that has lasted
  241. 8:43me over 20 years.
  242. 8:46I think it is the most beguiling topic
  243. 8:48in all of science. I'm biased of course.
  244. 8:52Um and I will never study anything
  245. 8:54different. I know that now. I'll study
  246. 8:56it to the end of my career and until the
  247. 8:58end of my life.
  248. 9:00Wow.
  249. 9:01I've never heard anybody say to me on
  250. 9:03this podcast that they would study
  251. 9:05the same topic for the rest of their
  252. 9:07life.
  253. 9:08And you're a young man. That's a you've
  254. 9:09got a long way to go.
  255. 9:10Actually, the amount you've been
  256. 9:11sleeping
  257. 9:12It's very kind of you to say. I I wish
  258. 9:14I'm I'm moving into the foothills of
  259. 9:16middle age rapidly, but
  260. 9:18no, I
  261. 9:20I'm so fortunate in what I do
  262. 9:22to have found it or for it to have found
  263. 9:25me. You know, if I won all of the money
  264. 9:27in the world tomorrow,
  265. 9:30I would genuinely genuinely not do
  266. 9:33anything different. Um,
  267. 9:36I am so fortunate Well, I probably start
  268. 9:39trying to fly like business class or
  269. 9:41first class. That would be nice. But
  270. 9:42other than that, um, I would do nothing
  271. 9:44different. And I
  272. 9:46I'm very mindful of that because that
  273. 9:48sounds very privileged. And I know a lot
  274. 9:50of people
  275. 9:53endure what they do for a living rather
  276. 9:56than enjoy what they do for a living.
  277. 9:59And I know how lucky I am. So, I don't
  278. 10:02mean to be dismissive of of people in
  279. 10:04that God, I just know how much I love
  280. 10:06what I do.
  281. 10:07You you asked a question now which is,
  282. 10:08um, you you you posed a question which
  283. 10:11many people have tried to answer. You
  284. 10:12gave the the answer from 30 years ago
  285. 10:14about, you know, why do we sleep? Um,
  286. 10:17and it dawned on me as you said that
  287. 10:20that I've never asked myself that
  288. 10:21question.
  289. 10:22I've never even pondered the thought of
  290. 10:24why I sleep. I mean, I know what happens
  291. 10:26when I sleep. But do I know why my body
  292. 10:29can't just find another way? Why can't
  293. 10:31my body stay awake for the 24 hours? I
  294. 10:33know some animals, they sleep half their
  295. 10:34brain and then the other half kind of
  296. 10:36has a nap and whatever. Why why why do
  297. 10:39we sleep?
  298. 10:40It it's a puzzling question because when
  299. 10:42you think about it from an evolutionary
  300. 10:44perspective, it makes no sense
  301. 10:47whatsoever.
  302. 10:48Sleep is utterly
  303. 10:51idiotic because when you're sleeping,
  304. 10:54firstly, you're not finding a mate,
  305. 10:56you're not reproducing, you're not
  306. 10:58foraging for food, you're not caring for
  307. 11:01your young. And worst of all, you're
  308. 11:03vulnerable to predation.
  309. 11:06Now, on any one of those grounds, but
  310. 11:08especially all of them as a collective,
  311. 11:10sleep should have been strongly selected
  312. 11:12against during the course of evolution.
  313. 11:16But from best we can tell, sleep evolved
  314. 11:19with life itself on this planet.
  315. 11:22And it has fought its way through
  316. 11:24heroically every step along the
  317. 11:27evolutionary path.
  318. 11:29And what that has told us is that sleep
  319. 11:31must be essential at the most basic of
  320. 11:34biological levels.
  321. 11:36And now we understand that Mother Nature
  322. 11:39didn't make a spectacular blunder with
  323. 11:41this thing called sleep. Sleep, for
  324. 11:43example, will restock the weaponry in
  325. 11:46your immune arsenal.
  326. 11:48And it will make you a more
  327. 11:50immune-sensitive individual. So, you're
  328. 11:52more immune-robust
  329. 11:54when you wake up.
  330. 11:55We also know that it regulates your
  331. 11:57blood sugar levels. It controls your
  332. 12:00appetite hormones. It also regulates
  333. 12:02your sex hormones, testosterone,
  334. 12:04estrogen.
  335. 12:06Um sleep upstairs within the brain will
  336. 12:08fixate memories and help you learn and
  337. 12:11remember. Sleep will de-escalate
  338. 12:13anxiety. It will reduce your emotional
  339. 12:16difficulties and traumas. Sleep will
  340. 12:19actually cleanse away the Alzheimer's
  341. 12:22toxic proteins that build up in the
  342. 12:24brain. You know, the list is endless.
  343. 12:26These are all of the reasons that we
  344. 12:29need to sleep.
  345. 12:31But why can't I just do what those
  346. 12:34animals do where they half of their
  347. 12:35brain falls asleep and the half of the
  348. 12:37brain stays awake? Is that at all linked
  349. 12:39to the fact that we we live in tribes?
  350. 12:40So, we are essentially, although we're,
  351. 12:43you know, there might be 10 people in
  352. 12:44the tribe, we're
  353. 12:46all 10% of the tribe. So, we can rest at
  354. 12:48different times and kind of cover each
  355. 12:49other's backs or
  356. 12:51Gosh, yeah. So, actually, there are two
  357. 12:53nested
  358. 12:55very insightful questions there. The
  359. 12:57first is this notion of what you're
  360. 12:59describing with just what we call
  361. 13:00unihemispheric
  362. 13:02sleep, which is just a fancy way of
  363. 13:04saying you can sleep with one half of
  364. 13:06your brain and the other half is wide
  365. 13:07awake. Now, there are only a few species
  366. 13:10that can do this. Um for example,
  367. 13:12aquatic mammals, dolphins are great
  368. 13:15example. We can place actually
  369. 13:17electrodes on their heads and you can
  370. 13:20see that one half of their brain will be
  371. 13:22fast asleep. It will be in deep, deep
  372. 13:25non-REM sleep. The other half of the
  373. 13:27brain will be frenetic, wide awake.
  374. 13:30And in part for them, the reason is
  375. 13:33because they need to maintain aquatic
  376. 13:35mobility. You know, they need to keep
  377. 13:37surfacing for air, otherwise, you know,
  378. 13:39that's not going to be a good outcome.
  379. 13:41We also know that
  380. 13:43uh
  381. 13:44birds or even many avian species will
  382. 13:46have unihemispheric sleep. And you can
  383. 13:50actually see this. There's some great
  384. 13:51YouTube videos online where they will
  385. 13:53film one half of the sort of the side of
  386. 13:56the the bird's face and the eye is
  387. 13:59closed. And what it means is that the
  388. 14:01other half of the brain, cuz the brain
  389. 14:03is actually the left half controls the
  390. 14:05right side, the right side controls the
  391. 14:06left side. So, that left side is now
  392. 14:09fast asleep, which is the right eye
  393. 14:10closed. And then you kind of pan around,
  394. 14:13and all of a sudden, the other eye is
  395. 14:15wide awake, and it's clearly looking
  396. 14:17about. Now, this is obviously not for
  397. 14:19aquatic surfacing to gain air. This is
  398. 14:21for a different reason. What happens is
  399. 14:23that in a flock, a bunch of birds will
  400. 14:27all land on a branch.
  401. 14:29Now, all of the folks in the middle,
  402. 14:32they get to sleep with both halves of
  403. 14:33their brain. They can sleep with both
  404. 14:35halves or just one half.
  405. 14:37All of the folks in the middle, they get
  406. 14:38to sleep with both halves. The
  407. 14:40unfortunate girl or guy who sort of
  408. 14:43lands at the end, the far end,
  409. 14:46they will actually sleep with one half
  410. 14:48of their brain. So, one half of the
  411. 14:50flock, the entire flock, has one eye,
  412. 14:53180° of sort of half panoramic view
  413. 14:58uh out. The other bird on the other end
  414. 15:00will have the other half of the brain
  415. 15:02asleep with the other eye awake, giving
  416. 15:05the other 180° view of protection uh
  417. 15:09vision. And therefore, the entire tribe
  418. 15:12has a 360°
  419. 15:15assessment. Now, you would think, in
  420. 15:17fairness, that once those guys or girls
  421. 15:20at the end have done their duty, they
  422. 15:22get to move into the middle and they get
  423. 15:24to sleep with both halves. No, that's
  424. 15:26not what happens. What they will do
  425. 15:28after a while is that they will stand
  426. 15:29up, they will turn around 180 degrees,
  427. 15:33sit back down, and switch the other
  428. 15:35sides of the brain.
  429. 15:37Wow.
  430. 15:37So,
  431. 15:38to to just be clear, the complexity
  432. 15:42of wiring and architecture that has to
  433. 15:45happen for one half of the brain to be
  434. 15:48deep in sleep and the other half to be
  435. 15:50wide awake is astronomically hard. I
  436. 15:53mean, it's incredibly difficult to
  437. 15:55create that wiring.
  438. 15:56What that tells me is that if sleep was
  439. 15:59dispensable, if it was negotiable,
  440. 16:03then Mother Nature would have just found
  441. 16:04a different way for us to get all of
  442. 16:06these brain and body benefits and not
  443. 16:08gone to all of the evolutionary trouble
  444. 16:11of figuring out this fancy wiring for
  445. 16:13half-brain sleep. In other words, you
  446. 16:16just can't get away from sleep. You have
  447. 16:18to sleep. But, your second question, I
  448. 16:21think, is is even more fascinating,
  449. 16:23which is as as a tribe, because we are a
  450. 16:26tribe species.
  451. 16:29Now, there is something else that we
  452. 16:30call your chronotype.
  453. 16:32Are you a morning type, evening type, or
  454. 16:34somewhere in between?
  455. 16:37And by the way, you don't get to decide.
  456. 16:39It's not your choice. You know, this
  457. 16:41notion of these go-getter type A's who
  458. 16:44say everyone has to be awake at 5:00 in
  459. 16:46the morning, you know, you
  460. 16:48go to the gym, you blast out a workout
  461. 16:50for an hour, and you're at the desk by
  462. 16:526:00 a.m.
  463. 16:54Um
  464. 16:55you have no choice. If you're an evening
  465. 16:57type, you're an evening type. It's
  466. 16:58hard-coded. We know that right now
  467. 17:00there's at least 22 different genes that
  468. 17:02dictate what you are, morning type,
  469. 17:04evening type, or somewhere in between.
  470. 17:06It's about a third-third split across
  471. 17:08the population.
  472. 17:09Why is it a split? Why are we nicely
  473. 17:12spread out across our chronotypes? For
  474. 17:15exactly the reason you described.
  475. 17:17Because when we're in a tribe, if we all
  476. 17:19sleep at the same time, we're all
  477. 17:21vulnerable for 8 hours.
  478. 17:24But if you were to insert some genetic
  479. 17:26variability into when people have a
  480. 17:28desire to sleep, you've got the morning
  481. 17:31types who maybe go to bed at 9:00 p.m.
  482. 17:34and are waking up, let's say, at 5:00
  483. 17:36a.m. And then you've got all of the
  484. 17:38extreme evening types who are going to
  485. 17:40bed at 2:00 a.m.
  486. 17:42and waking up at maybe 11:00 or midday.
  487. 17:45So that way, the everyone gets their 8
  488. 17:48hours of sleep, but the entire tribe,
  489. 17:51the nucleus of this group of Homo
  490. 17:53sapiens themselves, is only vulnerable
  491. 17:57for maybe just 2 or 3 hours. So it's a
  492. 17:59clever solution that Mother Nature has
  493. 18:02come up with to say, "Everyone gets
  494. 18:04their 8 hours, but as a species, you're
  495. 18:07only going to be vulnerable for 2 to 3
  496. 18:09hours max when everyone at least as a
  497. 18:11collective is sleeping."
  498. 18:13Absolute genius.
  499. 18:14I used to think it was a load of
  500. 18:15nonsense, this this chronotype thing. Um
  501. 18:17it was actually on this podcast where I
  502. 18:19learned about its existence, and then I
  503. 18:20went on YouTube to learn more, and your
  504. 18:22video came up of you explaining it.
  505. 18:24Because I thought I always pondered why
  506. 18:26my partner
  507. 18:28goes to bed super early,
  508. 18:29wakes up super early. I go to bed late,
  509. 18:32wake up late.
  510. 18:34Um
  511. 18:35I'm going to ask you this question
  512. 18:36actually cuz it cuz I've I've wondered
  513. 18:37this. In that situation where I'm
  514. 18:39sleeping in bed with a partner that has
  515. 18:40a different chronotype,
  516. 18:41Yeah.
  517. 18:43it can have an impact on my sleep,
  518. 18:45right? Because of the way that the our
  519. 18:47sleep cycles work, and the REM sleep,
  520. 18:48and the stage one, deep sleep, etc.,
  521. 18:49etc. If she's woken up when I'm pulling
  522. 18:52into REM sleep, I if she's woken up at
  523. 18:545:00 a.m., but at 5:00 a.m. because I've
  524. 18:56gone to bed late, my REM sleep has just
  525. 18:58begun.
  526. 18:59That has quite a significant impact on
  527. 19:01me, right?
  528. 19:02If she is waking you up,
  529. 19:04Yeah, if she's wake if she wakes me up,
  530. 19:05then it's non-trivial. And likewise, if
  531. 19:08you're waking her up as you're getting
  532. 19:10into bed on the front end of sleep.
  533. 19:13So, it's very difficult one of the
  534. 19:15things that couples will cite if they
  535. 19:18break up. Firstly, is
  536. 19:20usually about a third of them will cite
  537. 19:22sleep difficulties or sleep issues as a
  538. 19:25as a cause of the the breakup or at
  539. 19:28least as a contributing factor to that
  540. 19:30breakup.
  541. 19:311/3?
  542. 19:31Yeah.
  543. 19:32Jeez.
  544. 19:32That it's one of at least one of the
  545. 19:34factors.
  546. 19:35When you go with then in and when you
  547. 19:37double click to say, "Okay, then what is
  548. 19:39it about this sleep kind of tension
  549. 19:42between the two of you?"
  550. 19:44One of those things is a mismatch in
  551. 19:46chronotype.
  552. 19:48And you can see this when, you know,
  553. 19:50people I think this, you know, on dating
  554. 19:52profiles now someone was telling me
  555. 19:53people will even say like, "I'm a
  556. 19:55morning type or I'm an evening type." As
  557. 19:57if you're stating up front this is part
  558. 19:59of my identity and just FYI be
  559. 20:01forewarned because maybe it's been an
  560. 20:03issue for them in the past.
  561. 20:05This is why I often speak about
  562. 20:09the notion of what's called a sleep
  563. 20:11divorce to prevent a real one.
  564. 20:14Now, it's not for everyone. Um a sleep
  565. 20:17divorce is where you sleep in separate
  566. 20:19locations.
  567. 20:20And when we've surveyed people um both
  568. 20:23uh you in the from the sleep council in
  569. 20:25the United Kingdom and also in the
  570. 20:27National Sleep Foundation here in
  571. 20:28America,
  572. 20:30the data is about the same. One in four
  573. 20:32people will say that they sleep in
  574. 20:34different locations with their partner.
  575. 20:37So,
  576. 20:38almost a quarter of
  577. 20:40people in relationships will sleep in
  578. 20:42different locations. We think it's
  579. 20:44potentially an underestimate because if
  580. 20:46you survey people anonymously,
  581. 20:49then a third of them will report waking
  582. 20:52up at least in a different location the
  583. 20:55next morning.
  584. 20:57And part of the reason that it's a taboo
  585. 21:00is because people think, "Well, if I'm
  586. 21:02if we're not sleeping together, then
  587. 21:04we're not sleeping together." The exact
  588. 21:07opposite is true that when a couple is
  589. 21:09sleeping well,
  590. 21:11we know that the sex hormones are
  591. 21:13improved, testosterone men, estrogen, um
  592. 21:16and uh
  593. 21:18uh luteinizing hormone in women. We also
  594. 21:20know that your
  595. 21:22um desire to be intimate with your
  596. 21:25partner is increased. Uh what we found
  597. 21:27is that for an hour of extra sleep, if a
  598. 21:30woman gets an hour of extra sleep, her
  599. 21:33libido desire to be intimate with her
  600. 21:35partner increases by 14%.
  601. 21:38Now, to give you some context, the FDA
  602. 21:41drugs for improving or increasing libido
  603. 21:44in women, drugs such as Vyleesi here,
  604. 21:47clinical drugs, they will increase it by
  605. 21:49about 24% and that's a pharmacological
  606. 21:52agent. But here, just the added
  607. 21:54non-pharmacological benefit of 1 hour of
  608. 21:57extra sleep will get you more than 50%
  609. 21:59of the way there.
  610. 22:01So, I want to just remove that notion of
  611. 22:04the stigma
  612. 22:05of that if you're not sleeping together,
  613. 22:08you're not sleeping It's usually quite
  614. 22:10quite the opposite.
  615. 22:12Um I would say that
  616. 22:15part of the the challenge, though, is
  617. 22:19that
  618. 22:21if we look at all objective measures, if
  619. 22:23I measure your sleep and the sleep of
  620. 22:26your wife,
  621. 22:27if when you're sleeping separately
  622. 22:29versus when you're sleeping together,
  623. 22:31it's very likely that objectively you
  624. 22:33will both be sleeping worse when you're
  625. 22:35sleeping together. That's what the
  626. 22:36science tells us. However, what's
  627. 22:39interesting is that when you survey
  628. 22:41people and say, "How satisfied are you
  629. 22:44with your sleep?" which is a subjective
  630. 22:46measure, people will say, "I'm actually
  631. 22:49more satisfied with my sleep when I'm
  632. 22:50with my partner than when I'm sleeping
  633. 22:54alone." So, there's a mismatch here.
  634. 22:56Objectively, your sleep is better, but
  635. 22:58subjectively, you still prefer that. And
  636. 23:01of course, it's natural. you know, we
  637. 23:03there is safety, there's security in
  638. 23:05co-sleeping, there is this
  639. 23:08sort of connection that we get.
  640. 23:11You You can approach it if you want.
  641. 23:13Just be honest with yourself.
  642. 23:15And be honest with your partner.
  643. 23:18And you can start by saying, "Look, this
  644. 23:20isn't forever.
  645. 23:22I just want to say let's do an
  646. 23:24experiment for a week, 10 days. Let's
  647. 23:27Let's just try it and see how it goes.
  648. 23:30It doesn't need to be permanent."
  649. 23:31Because what you actually miss
  650. 23:34are the bookends of sleep.
  651. 23:36For the most part, the two of you are
  652. 23:38not conscious for most of the experience
  653. 23:40of sleeping together.
  654. 23:42It's really getting into bed and sort of
  655. 23:43having a kiss or a cuddle or and sort of
  656. 23:46waking up together in the morning and
  657. 23:47sort of
  658. 23:48Now, obviously, when you're a mismatched
  659. 23:50chronotype, that's also can be a
  660. 23:51challenge, too. So, you can still have a
  661. 23:54sleep divorce, but you can set up a a
  662. 23:57system where you will go in, you'll say
  663. 23:59your good nights, and you'll kind of get
  664. 24:01into bed, have a kiss and cuddle, and
  665. 24:02then you retreat to a separate location.
  666. 24:05And you can repeat that same process. Um
  667. 24:07so,
  668. 24:09I I don't want to sort of
  669. 24:11belabor the point of a of a sleep
  670. 24:13divorce, but um people can certainly
  671. 24:15explore There is something called a
  672. 24:17halfway house, which is called the
  673. 24:19Scandinavian method, which sounds far
  674. 24:21more salacious than it actually is. It's
  675. 24:24simply that you buy two beds, and you
  676. 24:26put them side by side in the same room,
  677. 24:29and therefore, the amount of disruption,
  678. 24:31physical um disruption that happens by
  679. 24:34way of sheets and movement, is
  680. 24:36decreased.
  681. 24:37But that doesn't solve it all. Sometimes
  682. 24:39there is snoring, uh sometimes there is
  683. 24:41sleep talking. Those things are not
  684. 24:43obviated by the Scandinavian method.
  685. 24:46When you think about where society is, I
  686. 24:48was I was I was going to ask you, you
  687. 24:49know, you said you wanted to to do the
  688. 24:51work you're doing now for the rest of
  689. 24:52your life.
  690. 24:53Um so, do you think the work you're
  691. 24:54doing now is going to become
  692. 24:56increasingly more important and
  693. 24:58relevant.
  694. 25:00I mean, is the problem going to get
  695. 25:01worse?
  696. 25:02Mhm.
  697. 25:02Or is it going to become less
  698. 25:04significant and less relevant? Based on
  699. 25:06the trajectory of societies, do you see
  700. 25:08it?
  701. 25:10You know, I'm
  702. 25:12mixed. I think when I wrote the book, I
  703. 25:14started writing uh
  704. 25:17the a book that was called Why We Sleep
  705. 25:19back in probably about 2014 or 15, and
  706. 25:22at that point sleep was the neglected
  707. 25:24stepsister in the health conversation of
  708. 25:27that day. You know, we were speaking a
  709. 25:29lot about diet and exercise, which was
  710. 25:30wonderful, but there was no voice of
  711. 25:33sleep.
  712. 25:35And I was so sad about that because I
  713. 25:36could see so much disease and suffering
  714. 25:38that was coming so clearly by way of a
  715. 25:41lack of sleep, but it wasn't there on
  716. 25:45the public buffet menu for consumption
  717. 25:48of knowledge.
  718. 25:49And so, that was part of the motivation
  719. 25:52for trying to write the book. So, I
  720. 25:55would say now,
  721. 25:56and this is not because of me or the
  722. 25:58book or anything like that, but is is
  723. 26:00sleep more of a conversation in this day
  724. 26:03and age than it was six or seven years
  725. 26:06ago. I think I would say yes, there is a
  726. 26:09greater awareness of of sleep.
  727. 26:12Um
  728. 26:14but
  729. 26:16with that awareness,
  730. 26:19I want I think one can still question
  731. 26:22the pragmatics, meaning
  732. 26:24just because we're talking about it more
  733. 26:26does not mean that people are still
  734. 26:29failing to either get the sleep that
  735. 26:32they need or that they are unable to get
  736. 26:36the sleep that they need. And those two
  737. 26:37things are different. One is that you
  738. 26:39are healthy and you can generate the
  739. 26:41sleep that you need, but you don't give
  740. 26:42yourself the opportunity, time, or life,
  741. 26:44I should say sometimes, cuz it's
  742. 26:46sometimes not your choice. Life does not
  743. 26:48give you the chance to get sleep. And if
  744. 26:49only you had the chance, you could
  745. 26:51sleep. That's one version. The second
  746. 26:53version is, "No, I'm giving myself the
  747. 26:55right opportunity to sleep, but because
  748. 26:58I'm anxious or because of other issues,
  749. 27:01I am not able to generate sleep. I
  750. 27:02suffer from insomnia and sleep
  751. 27:04problems."
  752. 27:05So, those two things I don't see having
  753. 27:09changed since
  754. 27:12you know, I think this public movement,
  755. 27:14this increasing movement of sleep
  756. 27:16conversation came on the table. So, in
  757. 27:18that regard, I'm more pessimistic than I
  758. 27:21am optimistic. And I think it will only
  759. 27:24get worse. If you look at rates of
  760. 27:26insomnia, for example, they're only
  761. 27:28increasing. They're only escalating.
  762. 27:30Rates of anxiety disorders, the very
  763. 27:32same thing. And those two things are
  764. 27:34intimately intertwined.
  765. 27:37So, I think
  766. 27:39I wish I my mission was extinguished
  767. 27:42within the next couple of years, because
  768. 27:44society started sleeping wonderfully
  769. 27:46well. I don't think that's going to be
  770. 27:48the case. So, I think I've got my work
  771. 27:50cut out for me
  772. 27:51um to try and help people with better
  773. 27:53sleep. Um
  774. 27:55Is it So, it's getting We're getting
  775. 27:57worse at sleeping?
  776. 27:59I think
  777. 28:00modernity is making it
  778. 28:04so much more difficult for us to sleep.
  779. 28:06Modernity? What's that?
  780. 28:08I think it when you think about
  781. 28:11you know, we often think about sleep as
  782. 28:12a biological process, and it very much
  783. 28:14is.
  784. 28:15And but
  785. 28:17also, it's so environmental as well as
  786. 28:21biological, meaning
  787. 28:24when you were to say, you know, "How did
  788. 28:26you sleep last night?" Think about all
  789. 28:28of the external factors that changed it.
  790. 28:31Well, I had to be up at this time. I had
  791. 28:33to catch a flight this time. My partner
  792. 28:35went to bed at this time, and she woke
  793. 28:37up at this time. There was this noise
  794. 28:39that sort of happened. I'm now sleeping
  795. 28:41in a hotel room." You know, there are
  796. 28:43countless externalities.
  797. 28:45And those externalities are shaped by
  798. 28:48this thing called the modern world. And
  799. 28:50in the modern world, if I could really
  800. 28:52be cynical, and I'm not someone, I'm
  801. 28:54very optimistic and I'm very
  802. 28:56non-cynical, but you could argue from a
  803. 28:58capitalistic standpoint that society
  804. 29:01does not want you sleeping.
  805. 29:03Because what society wants from a
  806. 29:05capitalistic point of view is that
  807. 29:07you're either producing
  808. 29:09or you're consuming.
  809. 29:10And when you're sleeping, you're neither
  810. 29:12producing and you're neither consuming.
  811. 29:15And so,
  812. 29:17there are lots of ways that I think
  813. 29:19society and the modern world has
  814. 29:22conspired,
  815. 29:23willfully or not, conspiratorially or
  816. 29:27not, to
  817. 29:31decrease and try to diminish sleep. In
  818. 29:33fact, I think the CEO of Netflix several
  819. 29:37years ago, and I'm sure that YouTube
  820. 29:39comments will correct me if I'm wrong
  821. 29:40here, but I believe his very statement
  822. 29:42was that we are
  823. 29:44we are deciding to commit war against
  824. 29:47sleep.
  825. 29:48That was their goal.
  826. 29:50And it just stunned me that, you know,
  827. 29:53that we're going to go to war with
  828. 29:55sleep. We're going to remove you from
  829. 29:57your sleep. So, there are lots of ways
  830. 29:59in in which I think society does not
  831. 30:01help us. Light is another good example.
  832. 30:04We are a dark-deprived society in this
  833. 30:06modern era because we're exposed to
  834. 30:08light. We are not giving ourselves the
  835. 30:11right temperature cues. You know, we go
  836. 30:13into an office where it's you know, 20°
  837. 30:17or 70° C, whatever it is, stock-stable.
  838. 30:20Then we come home and we regulate our
  839. 30:22temperature at home to be the same
  840. 30:24thing.
  841. 30:25We take on board probably too much
  842. 30:27caffeine in this day and age, although I
  843. 30:29am actually an advocate of drinking
  844. 30:31coffee and I can explain why, too.
  845. 30:34But anxiety, as I said, is a huge issue.
  846. 30:38All of these things are preventing and
  847. 30:41classic roadblocks to sleep.
  848. 30:45How many of us are getting the sort of
  849. 30:47recommended daily allowance of sleep as
  850. 30:50a percentage, do you know?
  851. 30:51It seems to be about
  852. 30:541/3 of
  853. 30:56most modern civilizations
  854. 30:59are failing to get the recommended 7 to
  855. 31:019 hours of sleep a night.
  856. 31:031/3 so roughly 30 35% 33% roughly.
  857. 31:07Yeah.
  858. 31:08And does that have geographic variants?
  859. 31:10I in some countries it's worse and some
  860. 31:12countries it's better. I'm thinking
  861. 31:13about the UK versus the US or you know,
  862. 31:15Japan or whatever.
  863. 31:16Yeah, it is. And in fact, you let me
  864. 31:19give numbers to the three countries that
  865. 31:21you described. Here in the United
  866. 31:24States, the average amount of sleep that
  867. 31:27people are getting is 6 hours and 29
  868. 31:32minutes. In the UK, it's not much
  869. 31:33better, 6 hours and 49 minutes. Japan
  870. 31:37was the worst, 6 hours and 22 minutes.
  871. 31:41Now, to be clear,
  872. 31:44that's the average.
  873. 31:46What that means is that there is still a
  874. 31:48large proportion of that bell-shaped
  875. 31:50distribution
  876. 31:52of people getting even less than that
  877. 31:55amount.
  878. 31:57Now, there are some countries that you
  879. 31:59look at that are actually sleeping much
  880. 32:02better than that. I think let me
  881. 32:05Mexico for example is is doing very
  882. 32:09well. If you look at Mexico City,
  883. 32:10people are actually sleeping not too far
  884. 32:13off from 8 hours. So, there is
  885. 32:15variability and we can try to understand
  886. 32:17why, which by the way just brings me
  887. 32:20back while I think about it to your
  888. 32:21comment of will my work be done not from
  889. 32:24the because I'm a scientist and I do I
  890. 32:26have a run a big sleep center at UC
  891. 32:28Berkeley, but the work I do as a
  892. 32:31hopefully a public advocate for sleep
  893. 32:33why I don't think it's going to change
  894. 32:35um,
  895. 32:36soon
  896. 32:37is because
  897. 32:38governments aren't really doing much
  898. 32:41about it and I've tried as best I can
  899. 32:43and if there is any government out there
  900. 32:45that listens to this that wants to work
  901. 32:46with me, I'd be delighted.
  902. 32:49I don't remember and maybe you can, but
  903. 32:52any major first world nation government
  904. 32:55that has had a public health campaign
  905. 32:57regarding sleep.
  906. 32:59And it stuns me because those same
  907. 33:02governments have had public health
  908. 33:04campaigns regarding, you know, eating,
  909. 33:07regarding smoking, regarding drunk
  910. 33:09driving, regarding risky behaviors, safe
  911. 33:12sex,
  912. 33:13loneliness,
  913. 33:14loneliness, mental health,
  914. 33:17suicide.
  915. 33:19Where is sleep in that equation?
  916. 33:23And it's such a fundamental ingredient.
  917. 33:26And in fact, almost all of those things
  918. 33:28that I've just described
  919. 33:30have an intimate relationship
  920. 33:33with sleep. I mean, suicide especially.
  921. 33:35We were starting to do a lot of work
  922. 33:37with this, although it's been hard to
  923. 33:38get funding. But what we found is that
  924. 33:41insufficient sleep is a precursor to
  925. 33:44suicide. That sleep disruption seems to
  926. 33:47predict both suicide ideation, in other
  927. 33:50words, suicidal thinking, suicide
  928. 33:53planning, and tragically, suicide
  929. 33:56completion as well.
  930. 33:58So, if we were to try to have
  931. 33:59governments create a public health
  932. 34:01campaign to pull this Archimedes lever
  933. 34:05on better sleep, there are so many other
  934. 34:07health benefits. You know, sleep is the
  935. 34:10tide that rises all the other health
  936. 34:12boats. It's almost like a
  937. 34:15it's like a mixing deck in a studio. You
  938. 34:17know, in those sound studios where
  939. 34:18you've seen it. And then there's that
  940. 34:19one button all the way to the end, the
  941. 34:21white button, sort of that when you move
  942. 34:23it up, sort of all of the other dials,
  943. 34:25the sort of the red, yellow, orange,
  944. 34:27green dials, they all move up at the
  945. 34:29same time as well. There's this like
  946. 34:30sort of one messed like one ring to rule
  947. 34:33them all. Sleep is that
  948. 34:35Archimedes lever. So, if governments
  949. 34:37could only execute on that, the health
  950. 34:40benefits would be manifold in terms of
  951. 34:43their consequences.
  952. 34:44It begs the question, you know, if I
  953. 34:46were to make you today
  954. 34:48president, prime minister, whatever, of
  955. 34:50the world,
  956. 34:51and you had to do, you know, just a few
  957. 34:53things to really fix the
  958. 34:57lack of sleep epidemic, there you go,
  959. 35:00diagnosed it. Um what would those things
  960. 35:02be if you were in charge? How would you
  961. 35:04redesign society to help us to sleep
  962. 35:06better?
  963. 35:09Gosh, it's such a good question and I've
  964. 35:11thought a lot about this
  965. 35:13it almost in reverse, which is to say
  966. 35:16why is it that we are struggling to get
  967. 35:19sleep? And there is no single answer.
  968. 35:21There are so many different reasons, and
  969. 35:23that's why it's actually a very
  970. 35:25challenging problem to solve.
  971. 35:28I would go through a descending level of
  972. 35:30steps. So, first I would start at the
  973. 35:32government level, and we would get those
  974. 35:34public health campaigns in order.
  975. 35:37Um next, I would go to the professional
  976. 35:40level, because there we have this
  977. 35:42mentality in business that, you know,
  978. 35:45sleep is for the soft among us, that
  979. 35:50less sleep equals more productivity.
  980. 35:54And that is just not true, and I can
  981. 35:56provide you with all of the evidence.
  982. 35:58So, we need to get rid of this sort of
  983. 36:00sleep machismo attitude in the
  984. 36:02workplace, where we wear wear our badge
  985. 36:04of honor of sleep deprivation on our
  986. 36:06arms. We need to get companies to
  987. 36:08actually start embracing sleep. And I
  988. 36:10can guarantee you, and I can give you
  989. 36:12all of the evidence as to why, if as a
  990. 36:15company, as a CEO, if you start
  991. 36:18prioritizing the sleep of your
  992. 36:20employees, you will be far better off as
  993. 36:23a company. You will be more
  994. 36:25product-based, and you will be more
  995. 36:27profitable and revenue generating.
  996. 36:30Sleep is the very best form of
  997. 36:32physiologically injected venture capital
  998. 36:34that you could ever wish for. And in
  999. 36:36fact, the RAND Corporation, which is an
  1000. 36:38independent survey corporation, what
  1001. 36:40they found is that at a national level,
  1002. 36:43insufficient sleep costs most nations
  1003. 36:46about 2% of their GDP.
  1004. 36:49So, here in America, that number was
  1005. 36:50$411 billion
  1006. 36:53of lost profit caused by insufficient
  1007. 36:55sleep. In the United Kingdom, it was
  1008. 36:57over $50 billion.
  1009. 36:58In Japan, it was over $120 billion.
  1010. 37:01If I could solve the sleep loss crisis
  1011. 37:03in the workplace, I could perhaps double
  1012. 37:06the health care benefit for many of
  1013. 37:07those countries, or I could halve the
  1014. 37:09out the education deficit in those
  1015. 37:11countries. So, the next level I would
  1016. 37:13target is
  1017. 37:14at business. Then next step down would
  1018. 37:16be medicine.
  1019. 37:18Medicine is a classic demonstration
  1020. 37:20here. We have junior doctors, or here in
  1021. 37:22America, they have doctor residency
  1022. 37:25programs, where people are working 20-30
  1023. 37:28hour shifts.
  1024. 37:30And so, already doctors are inculcated
  1025. 37:33into the mindset of the uselessness
  1026. 37:36of of sufficient sleep.
  1027. 37:39Across numerous countries, and I think
  1028. 37:41it was maybe over eight different
  1029. 37:43countries, we looked at the medical
  1030. 37:45curriculum.
  1031. 37:46And we asked, "How many hours of
  1032. 37:47education do doctors get about sleep?"
  1033. 37:51And what's strange is that, you know,
  1034. 37:52often doctors will you go in and you'll
  1035. 37:53have an appointment, they'll say, "Okay,
  1036. 37:54you know, how you eating?" And you know,
  1037. 37:56what's going on with the bathroom? How's
  1038. 37:58the toilet? Um and then, you know, how
  1039. 38:00are you sleeping?" As if sleep is one of
  1040. 38:02these universal health barometers. But
  1041. 38:04what we found is that most doctors will
  1042. 38:06only be given about an hour to an hour
  1043. 38:09and a half of sleep education during
  1044. 38:11their entire medical school education.
  1045. 38:15Which
  1046. 38:16blows my mind because it is 1/3 of their
  1047. 38:19patients' lives, but they're only given
  1048. 38:23about 90 minutes of education. So, no
  1049. 38:25wonder your doctors aren't treating your
  1050. 38:28sleep problems, thinking about your
  1051. 38:29sleep problems, understanding your sleep
  1052. 38:31It's not their fault. And plus, they're
  1053. 38:33sleep deprived anyway when they're being
  1054. 38:35trained.
  1055. 38:36Ironically, by the way,
  1056. 38:39doctors, junior doctors who've worked a
  1057. 38:4130-hour shift, when they finish that
  1058. 38:4430-hour shift and get back in their car,
  1059. 38:46they are 168%
  1060. 38:48more likely to get into a car accident
  1061. 38:51because of their lack of sleep and end
  1062. 38:53back up in the emergency room from where
  1063. 38:55they were just working, but now as a
  1064. 38:57patient. I mean,
  1065. 38:59this the paradox,
  1066. 39:01the irony just stuns me. So, I next
  1067. 39:03moved down to the level of medicine.
  1068. 39:05Then, I would go to education
  1069. 39:08because we don't get taught about sleep
  1070. 39:10in schools. Now, I never got one of
  1071. 39:13those special classes. You know, I got
  1072. 39:15sort of, you know, sexual education
  1073. 39:17classes, classes about drugs. No one
  1074. 39:20came in and told me about the benefits
  1075. 39:22of sleep. Why aren't we doing that? Then
  1076. 39:25next, I would move down into the family
  1077. 39:28because there is prejudice in families
  1078. 39:30with sleep. It's this notion of
  1079. 39:33parents of teenagers. And these
  1080. 39:36teenagers, by the way, it's not their
  1081. 39:38fault. They have a shift in their
  1082. 39:40chronotype, in their circadian rhythm,
  1083. 39:42that when they go through puberty, when
  1084. 39:44they're going through adolescence, they
  1085. 39:46get fast-forwarded in time. So, when
  1086. 39:48they were 8 or 9 years old, they would
  1087. 39:50be going to bed, you know, sort of early
  1088. 39:53in the evening, but now as teenagers,
  1089. 39:55they seem to be stubborn and they're
  1090. 39:57staying awake, staying awake until
  1091. 40:00midnight, 1:00 a.m., and they won't get
  1092. 40:03into bed. It is not their fault because
  1093. 40:06they have a biologically wired shift in
  1094. 40:10the tendency of when they want to wake
  1095. 40:12up and when they want to sleep. Why am I
  1096. 40:14bringing this up about this sort of
  1097. 40:16mismanagement in the home because
  1098. 40:18parents weekends they'll go into the
  1099. 40:21room of the teenagers they'll, you know,
  1100. 40:22pull open the the curtains they will
  1101. 40:24pull the covers off and they say you're
  1102. 40:26wasting the day.
  1103. 40:28You know, and firstly what they're doing
  1104. 40:30is probably trying to sleep off a debt
  1105. 40:33that we've lumbered them with during the
  1106. 40:35week because of this incessant model of
  1107. 40:37early school start times which I'll I'll
  1108. 40:39come back to.
  1109. 40:41But within the home if you ask parents
  1110. 40:44of teenagers what percent of parents
  1111. 40:47think that their teenagers are getting
  1112. 40:49sufficient sleep and about 70% of them
  1113. 40:51will say yes, my teenager is getting
  1114. 40:53sufficient sleep. When you look at the
  1115. 40:55data only about 15% of teenagers are
  1116. 40:58actually getting the sleep that they
  1117. 40:59need. So what happens is a parent-child
  1118. 41:03transmission of sleep neglect.
  1119. 41:05They're saying you're lazy, you're
  1120. 41:06slothful. So then what happens? Well, in
  1121. 41:1015-20 years time now that teenager has
  1122. 41:14got a teenage child, what do they do?
  1123. 41:17They go back in the room, they rip the
  1124. 41:19curtains open and they say you're
  1125. 41:19wasting the day because that's what they
  1126. 41:21were told. So we need to break that down
  1127. 41:24too and then finally we need to come to
  1128. 41:26the individual and we need to solve the
  1129. 41:28individuals sleep problem. So it's a
  1130. 41:30very long answer and I'm desperately
  1131. 41:32sorry to a very big question as to what
  1132. 41:34I would do if I was off for a day but I
  1133. 41:36hope that gives you some
  1134. 41:39sense of of the depth that I think we
  1135. 41:42need to go to. I've tried to think about
  1136. 41:43the question a lot. It's not
  1137. 41:45particularly well executed. I don't
  1138. 41:46think I was very eloquent there but I
  1139. 41:48hope that gives a sense.
  1140. 41:49It sounded perfectly eloquent to me. It
  1141. 41:51sounded like a manifesto so
  1142. 41:53um hopefully if there are people
  1143. 41:54listening from governments which I'm
  1144. 41:55sure there are cuz, you know,
  1145. 41:57I hear about that sometimes which is
  1146. 41:58quite bizarre but um I
  1147. 42:00I'm sure they'll be getting in touch
  1148. 42:01with you very quickly. Going back to the
  1149. 42:03top of that that stack on the company
  1150. 42:06level. So as a CEO or a CFO or an
  1151. 42:08employer whatever, um there are some
  1152. 42:11companies that are incentivizing their
  1153. 42:13team members to sleep, right? Is there
  1154. 42:14any data showing the efficacy of that?
  1155. 42:17There is data that we have, and it's
  1156. 42:21bidirectional, both the efficacy of when
  1157. 42:24you
  1158. 42:25increase sleep, and also the detriment
  1159. 42:28when you don't allow sleep. So, a great
  1160. 42:31example was, um,
  1161. 42:33NASA back in the 1980s,
  1162. 42:38they were looking at using naps in the
  1163. 42:42astronaut program, because when you're
  1164. 42:45up and you're orbiting Earth, you will
  1165. 42:47actually be cycling Earth, you know,
  1166. 42:50really quite quickly, and you will get
  1167. 42:52to see, depending on the orbit, maybe
  1168. 42:55somewhere between 10 to 15 sunrises
  1169. 42:58every 24 hours, which sounds, I mean,
  1170. 43:01amazing and remarkable, but trust me, in
  1171. 43:03terms of your sleep, it is very
  1172. 43:06dislocating.
  1173. 43:08So, they were looking at how to use naps
  1174. 43:11strategically to improve performance,
  1175. 43:13because the weakest link on any space
  1176. 43:16mission, and we've done some work with
  1177. 43:17NASA, um,
  1178. 43:19is the human being themselves. And they
  1179. 43:22can cause catastrophic failure. Now, if
  1180. 43:24you make an error at work, and you're
  1181. 43:26here terrestrially on the ground, you
  1182. 43:28know, it's probably non-trivial.
  1183. 43:30You make an error when you're up in
  1184. 43:32space,
  1185. 43:33it can be a big deal. So, they were
  1186. 43:35looking at that. And what they found was
  1187. 43:37that these naps, anywhere between 20
  1188. 43:40minutes to an hour, could increase
  1189. 43:44productivity
  1190. 43:45on these different tasks by about 34%
  1191. 43:48and increase general alertness by over
  1192. 43:5050%, and in fact, the data was so
  1193. 43:53powerful that it ended up being
  1194. 43:55transmitted to all of the terrestrial
  1195. 43:57workers on the ground that NASA would
  1196. 43:59start to It was what was called NASA
  1197. 44:01naps. It was a NASA nap culture. Now,
  1198. 44:04NASA isn't desperately compassionate by
  1199. 44:07any means. It's a great organization.
  1200. 44:09But they, just like companies like
  1201. 44:11Google or Facebook, they understand the
  1202. 44:14pounds and pennies sense, you know, the
  1203. 44:17dollars and the cents
  1204. 44:18version of productivity.
  1205. 44:20So anything that returns productivity,
  1206. 44:23they will invest in. And some of those
  1207. 44:24companies, you know, I um
  1208. 44:26I did some work at Google during a
  1209. 44:29sabbatical. And there on their campus,
  1210. 44:31they will have these nap pods and they
  1211. 44:33will have these what are called shh
  1212. 44:35rooms where you can go and you can take
  1213. 44:38a nap.
  1214. 44:39So think about 20 years ago, you would
  1215. 44:42never imagine a company paying you to
  1216. 44:46sleep on the job. If you were caught
  1217. 44:47sleeping on the job, you'd probably be
  1218. 44:49fired. Now companies are incentivizing
  1219. 44:51it. Not because they are thinking
  1220. 44:54compassionately or empathetically about
  1221. 44:56the health or the wellness of their
  1222. 44:58individuals. It is because they
  1223. 44:59understand that it transacts marked
  1224. 45:01productivity. So NASA was a good
  1225. 45:03example. When you give sleep, you get
  1226. 45:05something back. But I can go back to the
  1227. 45:07reverse of that.
  1228. 45:09Why we think that a lack of sleep does
  1229. 45:12not equal more productivity is for at
  1230. 45:14least five reasons. First, when you
  1231. 45:16survey, and we've we can do these
  1232. 45:18studies in the in the laboratory, too.
  1233. 45:20When you undersleep employees, they will
  1234. 45:23choose less challenging problems. So if
  1235. 45:26you give them an array of work problems,
  1236. 45:28they will just simply, you know, check
  1237. 45:30email, they'll listen to phone messages.
  1238. 45:32They don't dig into deep project work.
  1239. 45:34Second, of the problems that they do
  1240. 45:37take on in their work, they will produce
  1241. 45:40fewer creative solutions.
  1242. 45:42And after all, creativity and ingenuity
  1243. 45:45are supposed to be the two engines that
  1244. 45:47drive businesses forward in terms of
  1245. 45:50their productivity and their revenue.
  1246. 45:53The third that interesting finding that
  1247. 45:55we've discovered is that when underslept
  1248. 45:57employees start working in teams,
  1249. 46:00they will slack off. They won't do their
  1250. 46:03work. They will let other people do
  1251. 46:04their work. It's what we call social
  1252. 46:06loafing. So, they ride the coattails of
  1253. 46:08other people's hard work, which won't
  1254. 46:11breed a good atmosphere in your company.
  1255. 46:13You know, trust me.
  1256. 46:15The fourth thing that we found is that
  1257. 46:17underslept employees are more deviant.
  1258. 46:20That they're more likely to fudge data
  1259. 46:22in spreadsheets. They're more likely to
  1260. 46:24falsely claim uh money for reimbursement
  1261. 46:27that was inappropriate.
  1262. 46:30The final thing is that a lack of sleep
  1263. 46:31will go all the way to the top of the
  1264. 46:33business chain. What we found is that
  1265. 46:36the more or less sleep that a business
  1266. 46:38leader has had from one night to the
  1267. 46:40next to the next, the more or less
  1268. 46:43charismatic that employees will rate
  1269. 46:46that business leader from one day to the
  1270. 46:49next to the next, even though the
  1271. 46:51employees themselves, they know nothing
  1272. 46:54about the sleep that that CEO has been
  1273. 46:56getting. It's evidential in how
  1274. 46:59charismatic that CEO is.
  1275. 47:02So, you can add all of these things up
  1276. 47:04and no wonder you
  1277. 47:07if you don't snooze, you lose in the
  1278. 47:09case of business in that regard. That's
  1279. 47:11why I can produce, I think, a
  1280. 47:13non-trivial case for business. By the
  1281. 47:15way, the other aspect that is hugely
  1282. 47:18costly to businesses and when I go and
  1283. 47:20speak to businesses about why they
  1284. 47:22should value sleep,
  1285. 47:25if you offer it on the grounds of again
  1286. 47:27sort of compassion or mental health,
  1287. 47:31they probably don't want to listen. When
  1288. 47:32you convert it into the cost to the
  1289. 47:33company and how much it's fleecing them
  1290. 47:36in terms of their prof- profits, then
  1291. 47:38they start to pay attention.
  1292. 47:40Underslept employees will
  1293. 47:43take on average about 11 more days
  1294. 47:47uh sick days throughout the year
  1295. 47:49relative to well-slept individuals. So,
  1296. 47:51you're essentially just paying people
  1297. 47:53additionally for 11 days of work that
  1298. 47:55they will never give you when you are
  1299. 47:57under sleeping them. Secondly, the
  1300. 47:59utilization of health care resources
  1301. 48:02increases by about 80%.
  1302. 48:05So, the cost to either you, the company
  1303. 48:07here in the US where your company is
  1304. 48:09paying for your health care, or the cost
  1305. 48:11to the government, for example, in the
  1306. 48:12United Kingdom is astronomical.
  1307. 48:16And also then the co- what we call
  1308. 48:19comorbid diseases, your rates of
  1309. 48:21obesity, diabetes, cardiovascular
  1310. 48:24disease, mental health conditions, all
  1311. 48:26of these things escalate as under slept
  1312. 48:29employees continue to get even more
  1313. 48:31under slept.
  1314. 48:33So, there is no strong case that I've
  1315. 48:36seen
  1316. 48:38that leads me to think
  1317. 48:40businesses should foster the mentality
  1318. 48:43of insufficient sleep. Quite the
  1319. 48:45opposite. So, that's hopefully an answer
  1320. 48:47to a question. We can look at it
  1321. 48:48bi-directionally. When we give sleep
  1322. 48:49back, do you get productivity? Yes. When
  1323. 48:51you take sleep away, the things implode
  1324. 48:53rapidly? Yes. And is it costly to your
  1325. 48:56company? Very much so.
  1326. 48:58On that point of naps, and you know,
  1327. 49:00Google sleep pods, naps, and things like
  1328. 49:02that. There was a point in my life where
  1329. 49:04I because I learned about REM sleep and
  1330. 49:07the importance of REM sleep and deep
  1331. 49:08sleep, and that happens a little bit
  1332. 49:10further on into my, you know, the
  1333. 49:1290-minute Look at me trying to tell a
  1334. 49:14sleep expert about this.
  1335. 49:15No, I love it.
  1336. 49:16But do you see what I mean? Like, this
  1337. 49:17is my very This is my monkey brain. So,
  1338. 49:19I didn't understand the subject matter
  1339. 49:21very well. I still really don't, to be
  1340. 49:22honest, but in the first It takes me a
  1341. 49:25significant amount of time to get to
  1342. 49:27deep sleep into REM sleep.
  1343. 49:29How long on average would would you say
  1344. 49:30it takes for it for some, you know,
  1345. 49:32Yeah, so you will probably go into light
  1346. 49:35sleep in the first 10 to 15 minutes.
  1347. 49:36Then you'll go down into deep sleep.
  1348. 49:38You'll stay there for about 30, 40
  1349. 49:41minutes. Then you'll start to rise back
  1350. 49:43up and you'll pop up and you'll have a
  1351. 49:44short REM sleep period. And then you
  1352. 49:47complete the non-REM to REM cycle after
  1353. 49:50about 90 minutes, and back down you go
  1354. 49:52again, down into non-REM, and up into
  1355. 49:55REM. So, on average for human beings,
  1356. 49:57it's 90 minutes.
  1357. 49:58So, I therefore assumed that napping
  1358. 50:01really does nothing, because I thought,
  1359. 50:03well, it takes me so long to get to REM
  1360. 50:04sleep and to deep sleep that there's If
  1361. 50:07I've got 15 minutes, 20 minutes to to
  1362. 50:09nap, it's just a waste of time.
  1363. 50:11Right.
  1364. 50:12Was I wrong, or was I right?
  1365. 50:14You were
  1366. 50:16understandably wrong.
  1367. 50:18Okay, good.
  1368. 50:20I'm happy because I I've always rejected
  1369. 50:22naps because I thought they didn't
  1370. 50:23matter, because it takes me so long to
  1371. 50:25get to a restorative state anyway, so.
  1372. 50:27So, we've done lots of different studies
  1373. 50:29with naps, we and other colleagues, too.
  1374. 50:32And what we found is that naps can
  1375. 50:34transact some fantastic benefits. They
  1376. 50:36can improve cardiovascular health, lower
  1377. 50:38blood pressure.
  1378. 50:40They can improve your learning and
  1379. 50:42memory abilities.
  1380. 50:44They can reset the emotional
  1381. 50:48north of your magnetic compass in a good
  1382. 50:50way, where you can de-escalate negative
  1383. 50:53emotions and increase positive emotions.
  1384. 50:56Um so,
  1385. 50:57naps certainly are a good thing, but
  1386. 51:00with a big caveat that I'll come back
  1387. 51:02to.
  1388. 51:03Um yes, you're right in the sense that
  1389. 51:06to get a full cycle of sleep and to get
  1390. 51:09into REM sleep, you would probably have
  1391. 51:11to make that nap about 90 minutes. And
  1392. 51:14in fact, a lot of the studies that we
  1393. 51:16do, we will use a 90-minute nap duration
  1394. 51:19of time so that the brain can cycle
  1395. 51:22through all of those different stages of
  1396. 51:24sleep.
  1397. 51:25But you don't need to, nor would I
  1398. 51:26suggest that you do.
  1399. 51:29What we found is that different stages
  1400. 51:30of sleep perform different functions for
  1401. 51:33the brain at different times of night.
  1402. 51:36There are actually four separate stages,
  1403. 51:38stages one through four, increasing in
  1404. 51:40their depth of sleep. So, stages three
  1405. 51:42and four are those really deep stages of
  1406. 51:45non-REM sleep. Stages one and two,
  1407. 51:46that's the lighter form of non-REM.
  1408. 51:49And then you have rapid eye movement
  1409. 51:50sleep, or what we think of as dream
  1410. 51:51sleep.
  1411. 51:52And people will sometimes say to me,
  1412. 51:54"How do I get more REM sleep? Or how do
  1413. 51:56I get more deep sleep?" And my response
  1414. 51:59to them is, "Why do you want to get more
  1415. 52:01REM sleep?" And their answer is, "Well,
  1416. 52:02isn't that the good stuff?"
  1417. 52:05And it turns out that there is no good
  1418. 52:07stuff. It's all good stuff. You know,
  1419. 52:09maybe with the exception of that light
  1420. 52:12stage one non-REM sleep, that's shallow
  1421. 52:14sleep and we typically don't like to see
  1422. 52:16too much of that. But stage two non-REM
  1423. 52:18sleep, three and four, they all have
  1424. 52:20their different functions that we've
  1425. 52:22discovered. And REM sleep has its
  1426. 52:23functions.
  1427. 52:25So, you need all of them. You can't
  1428. 52:26short short shortchange any of them. But
  1429. 52:29for a nap,
  1430. 52:31what we found is that you can get
  1431. 52:33nice benefits for things like your
  1432. 52:35learning and your memory, and it can
  1433. 52:37even reduce some level of anxiety
  1434. 52:40up to about 20 minutes. You can In fact,
  1435. 52:43you can nap, I think the study one of
  1436. 52:45the studies, they brought a nap down to
  1437. 52:47about 9 minutes in duration, and there
  1438. 52:49were still some basic improvements for
  1439. 52:52your sort of general level of alertness
  1440. 52:54and reaction time. For example, if
  1441. 52:55you're an athlete, that's that's
  1442. 52:57non-trivial.
  1443. 52:58So, um
  1444. 53:00so, the reason I would say
  1445. 53:03be careful with naps is for two main
  1446. 53:07um sort of suggestions. The first is,
  1447. 53:09try not to nap for about longer than 20
  1448. 53:11minutes, because once you go past 20
  1449. 53:13minutes, you really start to go down
  1450. 53:15into those deeper stages of non-REM
  1451. 53:17sleep. And if you wake up after about 45
  1452. 53:20minutes or 60 minutes,
  1453. 53:23it's not a problem. I'm not suggesting
  1454. 53:24that you shouldn't or you couldn't. I'm
  1455. 53:27just saying be aware, because when you
  1456. 53:28come out of that deep sleep and you wake
  1457. 53:30up from that deep sleep, normally that's
  1458. 53:32not how you wake up. You will usually
  1459. 53:34wake up out of lighter stages of sleep
  1460. 53:37or out of REM sleep. It's rare that we
  1461. 53:39wake up out of deep sleep. But if you
  1462. 53:40nap and you snap for about 40 minutes,
  1463. 53:43you'll probably go down into deep sleep.
  1464. 53:46And at that point, what if you wake up
  1465. 53:48and your alarm goes off,
  1466. 53:49then you're going to feel almost
  1467. 53:51miserable and worse than you did before
  1468. 53:53the nap, because you have what's called
  1469. 53:55sleep inertia, which is essentially a
  1470. 53:58sleep hangover,
  1471. 53:59where the brain is still sort of pulled
  1472. 54:02back into that deep sleep state, and it
  1473. 54:05can take you almost an hour before you
  1474. 54:07feel like you're back up to operating
  1475. 54:09temperature and you're up to motorway
  1476. 54:10speed.
  1477. 54:12So, I would say keep it 20 minutes, and
  1478. 54:14you don't suffer too much of that
  1479. 54:15inertia. You still get some nice
  1480. 54:18benefits.
  1481. 54:19Also, don't nap too late in the
  1482. 54:21afternoon.
  1483. 54:22Also, the final part is if you are
  1484. 54:25struggling with sleep at night, if
  1485. 54:27you're someone who has insomnia or sleep
  1486. 54:29difficulties, do not nap during the day.
  1487. 54:33It's the worst thing that you can be
  1488. 54:34doing.
  1489. 54:35Because
  1490. 54:36when we're awake during the day, we
  1491. 54:38build up a sleepiness chemical in our
  1492. 54:40brain. It's called adenosine.
  1493. 54:43And the longer that we're awake, the
  1494. 54:44more adenosine that builds up, the more
  1495. 54:46adenosine that builds up, the sleepier
  1496. 54:48and sleepier that we feel.
  1497. 54:51And when we sleep, the brain gets the
  1498. 54:52chance to clear away all of that
  1499. 54:55adenosine, all of that sleepiness.
  1500. 54:57And somewhere between 7 to 9 hours after
  1501. 54:59sleeping a full night, the brain has
  1502. 55:02evacuated all of that sleepiness
  1503. 55:05chemical, all of that adenosine, so that
  1504. 55:07then we should wake up and we should
  1505. 55:09feel refreshed and restored and not
  1506. 55:12needing caffeine to to function.
  1507. 55:15Why is that relevant to naps? Well, it's
  1508. 55:17relevant to naps because when you take a
  1509. 55:19nap, you're essentially it's like a
  1510. 55:21pressure valve on a cooker. Pshh, you're
  1511. 55:24just releasing some of that healthy
  1512. 55:26sleepiness that you've been building up.
  1513. 55:28And therefore, if you are struggling
  1514. 55:29with sleep at night, and then you nap
  1515. 55:31during the day, it's terrible because
  1516. 55:34you're taking away all of that healthy
  1517. 55:36good weight of sleepiness that we've
  1518. 55:39been trying to build up on your
  1519. 55:40shoulders to give you the best chance of
  1520. 55:43a good night of sleep.
  1521. 55:45That's why I would say if you are
  1522. 55:47suffering from insomnia, don't nap
  1523. 55:48during the day. Also, even if you are if
  1524. 55:51you don't struggle with sleep at night,
  1525. 55:53try not to nap after about 3:00 p.m. in
  1526. 55:56the afternoon or 2:00 p.m.
  1527. 55:58Napping late in the afternoon or in the
  1528. 56:00early evening, it's a little bit like
  1529. 56:02snacking before your main meal. It just
  1530. 56:05takes the appetite off your sleep
  1531. 56:07hunger. So, try not to do that. But,
  1532. 56:09naps, for the most part, if you don't
  1533. 56:11struggle with sleep, they are wonderful
  1534. 56:13things. Just keep in mind the 20-minute
  1535. 56:15sort of idea.
  1536. 56:16You mentioned caffeine there. A topic
  1537. 56:18I've mulled over
  1538. 56:20over and over again on this
  1539. 56:21show.
  1540. 56:22Um because as I've said to uh maybe
  1541. 56:24three or four of my guests now,
  1542. 56:27it feels like caffeine is a miracle drug
  1543. 56:30that comes with no apparent cost. But,
  1544. 56:32when I think about things like anxiety
  1545. 56:34and I don't know, shallow sleep states.
  1546. 56:36I've always pondered that maybe caffeine
  1547. 56:38is playing a role in that. You said you
  1548. 56:40you're you're pro-caffeine. You're a
  1549. 56:41caffeine drinker yourself.
  1550. 56:43So, I am not a caffeine drinker myself,
  1551. 56:45but I am pro-coffee.
  1552. 56:48Oh, okay.
  1553. 56:48And I'm I'll tell you why I'm very
  1554. 56:51thoughtful about my wording between
  1555. 56:53caffeine and coffee there. And to your
  1556. 56:56point, it's a it's another astute one,
  1557. 56:58which is
  1558. 57:00it would you know, is it a miracle drug
  1559. 57:02with no cost?
  1560. 57:05In biology and medicine, there is almost
  1561. 57:08no free lunch.
  1562. 57:11Um and
  1563. 57:14that is true when it comes to caffeine
  1564. 57:16and sleep. So,
  1565. 57:18perhaps I'll give the skinny on caffeine
  1566. 57:21and how it impacts your sleep, but then
  1567. 57:23circle back around to what seems an
  1568. 57:25oxymoronic statement for me, which is
  1569. 57:27why I'm still pro-coffee.
  1570. 57:30Um caffeine will hurt your sleep in
  1571. 57:33probably at least
  1572. 57:35three ways, some of which you most
  1573. 57:38people are not aware of.
  1574. 57:39The first issue is the duration of its
  1575. 57:42action.
  1576. 57:43So, caffeine has what we call a
  1577. 57:45half-life of about 5 to 6 hours. In
  1578. 57:48other words, after about 5 to 6 hours,
  1579. 57:51half of that caffeine is still in your
  1580. 57:53system.
  1581. 57:54What that means is that caffeine has a
  1582. 57:55quarter-life
  1583. 57:57of somewhere between 10 to 12 hours.
  1584. 58:00So, if you have a cup of coffee at noon,
  1585. 58:02at midday,
  1586. 58:04a quarter of that caffeine is still in
  1587. 58:06your brain at midnight.
  1588. 58:08So, having a cup of coffee at noon, and
  1589. 58:11it's
  1590. 58:12hyperbole in truth, probably or it's a
  1591. 58:14little bit hyperbolic, but it's almost
  1592. 58:16the equivalent of
  1593. 58:18a coffee at noon is the equivalent of,
  1594. 58:19you know, tucking yourself into bed and
  1595. 58:21just before you turn the lights out, you
  1596. 58:23swig a quarter of a cup of coffee and
  1597. 58:25you hope for a good night's of sleep,
  1598. 58:27and it's probably not going to happen.
  1599. 58:29So, that's the first thing to keep in
  1600. 58:30mind is the
  1601. 58:31timing of of caffeine.
  1602. 58:34The second is that caffeine is a
  1603. 58:36stimulant. Now, everyone knows this.
  1604. 58:38Everyone knows that caffeine can make
  1605. 58:40you more alert and more awake. By the
  1606. 58:42way, how does it do that? Um, it comes
  1607. 58:44back to adenosine, which is the chemical
  1608. 58:46that we spoke about, the sleepiness
  1609. 58:48chemical.
  1610. 58:49It's no coincidence that those two
  1611. 58:50things sound the same at the end of the
  1612. 58:52name, caffeine and adenosine.
  1613. 58:55Caffeine will actually race into your
  1614. 58:57brain and it will latch onto the
  1615. 58:59adenosine receptors, the welcome sites
  1616. 59:02in your brain. And it has very sharp
  1617. 59:04elbows and it will force away the
  1618. 59:06adenosine from those receptors and it
  1619. 59:09will hijack those receptors.
  1620. 59:11Now, at this point you may be thinking,
  1621. 59:12well, hang on a second. If it's latching
  1622. 59:14onto those sleepiness chemical
  1623. 59:16receptors, shouldn't caffeine make you
  1624. 59:19more sleepy? And the answer is no,
  1625. 59:21because what it does is it just latches
  1626. 59:23onto the receptor and it inactivates it,
  1627. 59:26essentially. So, it masks the receptor.
  1628. 59:30What caffeine does then is race into
  1629. 59:33your brain. You've got all of this
  1630. 59:35sleepiness at 9:00 p.m. or 10:00 p.m.
  1631. 59:37You have an espresso cuz you're trying
  1632. 59:39to power through and finish the report
  1633. 59:41or, you know, the presentation for your
  1634. 59:43sort of your pitch for your deck for
  1635. 59:45your startup company.
  1636. 59:47And that caffeine races in, it latches
  1637. 59:49onto the adenosine receptors,
  1638. 59:52and blocks the signal of adenosine. So,
  1639. 59:55now your brain was thinking, "I'm
  1640. 59:56starting to get tired. It's 10:00 p.m."
  1641. 59:59But now, all of a sudden that signal is
  1642. 1:00:01blocked.
  1643. 1:00:02And it caffeine is like hitting the mute
  1644. 1:00:05button on your television remote
  1645. 1:00:07controller. It just muts the signal of
  1646. 1:00:09sleepiness. So, now you think, "Well,
  1647. 1:00:10now I don't feel sleepy anymore." And
  1648. 1:00:13here's the danger
  1649. 1:00:14that even though well, when the caffeine
  1650. 1:00:16is in your system and it's latched onto
  1651. 1:00:18the receptors, that adenosine is still
  1652. 1:00:20there. It's not going away. In fact, if
  1653. 1:00:23anything, during the course of the
  1654. 1:00:25caffeine in your system, it continues to
  1655. 1:00:27build and build.
  1656. 1:00:29And now, when the caffeine finally gets
  1657. 1:00:30metabolized and excreted out of your
  1658. 1:00:32system, not only do you go back to the
  1659. 1:00:35sleepiness that you had many hours
  1660. 1:00:37before, it's that plus all of the
  1661. 1:00:40adenosine sleepiness that's been
  1662. 1:00:41building up during that time in between.
  1663. 1:00:44So, you get hit with this huge tsunami
  1664. 1:00:46wave of sleepiness, and that's what we
  1665. 1:00:48call the caffeine crash.
  1666. 1:00:51So, the one of the issues So, that's
  1667. 1:00:54sort of caffeine in terms of how it
  1668. 1:00:55works and its timing. Another issue is
  1669. 1:00:57that it creates anxiety, just as you
  1670. 1:01:00said.
  1671. 1:01:01And anxiety is probably one of the
  1672. 1:01:03greatest enemies of sleep. It's one of
  1673. 1:01:05the principal reasons that underlies
  1674. 1:01:07insomnia is a physiological state of
  1675. 1:01:09anxiety, that your fight or flight
  1676. 1:01:11branch of the nervous system is
  1677. 1:01:12ratcheted up. That's what caffeine will
  1678. 1:01:15do. It needs to do the opposite for you
  1679. 1:01:17to fall asleep. That's why you can have
  1680. 1:01:19what we call the tired but wired
  1681. 1:01:20phenomenon, where you say, I'm so
  1682. 1:01:22desperately tired. I am so tired,
  1683. 1:01:25but I'm just so wired that I can't fall
  1684. 1:01:27asleep. It's because your nervous system
  1685. 1:01:29is too amped up. Caffeine will trigger
  1686. 1:01:32that amping up.
  1687. 1:01:33Then at that point, if you're struggling
  1688. 1:01:35to fall asleep because you've got too
  1689. 1:01:36much caffeine on board, it is what we
  1690. 1:01:38call anxiogenic. So now you start to
  1691. 1:01:41worry.
  1692. 1:01:42And the last thing you need to do when
  1693. 1:01:45your head hits the pillow for good sleep
  1694. 1:01:47is worry. Because when you start to
  1695. 1:01:48worry, you start to ruminate. And when
  1696. 1:01:51you ruminate, you catastrophize.
  1697. 1:01:54And when you catastrophize, you're dead
  1698. 1:01:56in the water for the next 2 hours when
  1699. 1:01:58it comes to sleep. Because we have this
  1700. 1:02:00sense that, you know, things at night,
  1701. 1:02:03in the darkness of night,
  1702. 1:02:06are so much bigger than they are in the
  1703. 1:02:08brightness of day.
  1704. 1:02:10And we start worrying, you know, in this
  1705. 1:02:12modern era, we're constantly on
  1706. 1:02:14reception.
  1707. 1:02:15And very rarely do we do reflection.
  1708. 1:02:18Unfortunately, the only time we we
  1709. 1:02:20typically do reflection is when we turn
  1710. 1:02:22off the light and our head hits the
  1711. 1:02:23pillow. And that is the last time you
  1712. 1:02:26want to be doing reflection. So that's
  1713. 1:02:28the the second problem with caffeine.
  1714. 1:02:29It's anxiogenic, and it only makes you,
  1715. 1:02:32sort of, almost like the Woody Allen
  1716. 1:02:33neurotic of the sleep world.
  1717. 1:02:35The final part of caffeine is that it's
  1718. 1:02:38very good at blocking your deep sleep.
  1719. 1:02:41So we've done a number of these studies
  1720. 1:02:42where we'll give people a standard dose
  1721. 1:02:44of caffeine, let's say, 150 mg to 200
  1722. 1:02:47mg, which is probably, you know, a cup
  1723. 1:02:49and a half of good strong coffee.
  1724. 1:02:52And then we put you to bed and we look
  1725. 1:02:53at the amount of deep sleep. And it will
  1726. 1:02:55strip away your deep sleep by about
  1727. 1:02:58somewhere between 15 to 30%.
  1728. 1:03:01Now, to put that in context, to drop
  1729. 1:03:04your deep sleep by 30%, I'd probably
  1730. 1:03:06have to age you by about 40 years, 4 0.
  1731. 1:03:10Or you could do it every night with an
  1732. 1:03:12espresso with with dinner. And that's
  1733. 1:03:14one of the problems. People will say to
  1734. 1:03:16me, "Look, I'm one of those people who I
  1735. 1:03:18can have two espressos with dinner and I
  1736. 1:03:21fall asleep fine and I stay asleep. So,
  1737. 1:03:23no harm, no foul." Well, not necessarily
  1738. 1:03:26because even if you fall asleep and you
  1739. 1:03:28stay asleep, you're not aware of the
  1740. 1:03:30lack of the deep sleep that you're not
  1741. 1:03:32getting because of the caffeine. And so,
  1742. 1:03:34now you wake up the next day and you
  1743. 1:03:36think, "Well,
  1744. 1:03:37I don't remember having a hard time
  1745. 1:03:38falling asleep. I don't remember waking
  1746. 1:03:40up, but now I'm reaching for two or
  1747. 1:03:42three cups of coffee the next morning
  1748. 1:03:44rather than my standard one cup of
  1749. 1:03:45coffee because I don't feel refreshed
  1750. 1:03:47and restored by my sleep because I was
  1751. 1:03:49lacking the amount of deep sleep."
  1752. 1:03:51And deep sleep, what does that rob us
  1753. 1:03:52of? The lack of deep sleep?
  1754. 1:03:54So, lack of deep sleep deep sleep is
  1755. 1:03:56critical for regulating your
  1756. 1:03:57cardiovascular system. It's the time
  1757. 1:03:59when we do replenish the immune system.
  1758. 1:04:02It also regulates your metabolic system,
  1759. 1:04:04so it controls the hormones such as
  1760. 1:04:07insulin that will regulate your blood
  1761. 1:04:09sugar and you will become blood sugar
  1762. 1:04:10dysregulated without sufficient deep
  1763. 1:04:12sleep. Upstairs in the brain, deep sleep
  1764. 1:04:15will um strengthen and consolidate and
  1765. 1:04:17secure new memories into your brain.
  1766. 1:04:20They will prevent those memories from
  1767. 1:04:21being forgotten. Deep sleep is also the
  1768. 1:04:24time when we cleanse the brain of
  1769. 1:04:25metabolic toxins, particularly the
  1770. 1:04:27toxins that are related to Alzheimer's
  1771. 1:04:29disease. So, getting a lack of deep
  1772. 1:04:31sleep is, I would say, a non-trivial
  1773. 1:04:33thing um
  1774. 1:04:35in that regard.
  1775. 1:04:37But,
  1776. 1:04:38I don't want to be also puritanical here
  1777. 1:04:42and this is where I'm going to change my
  1778. 1:04:44title tune.
  1779. 1:04:46I am not here to tell anyone how to live
  1780. 1:04:49their life. I have no right to tell
  1781. 1:04:51anyone how to live their life. I'm just
  1782. 1:04:53a scientist.
  1783. 1:04:55All I want to try and do is gift you the
  1784. 1:04:57science and the knowledge of sleep so
  1785. 1:04:59that you can make an informed choice.
  1786. 1:05:02And after all, and the same is true for
  1787. 1:05:04alcohol too and sleep, you know, life is
  1788. 1:05:07to be lived to a certain degree.
  1789. 1:05:10You know, no one wants to be the
  1790. 1:05:11healthiest guy in the graveyard.
  1791. 1:05:13I don't want to be that way, too. I want
  1792. 1:05:15to live life just with moderation. The
  1793. 1:05:19reason I don't drink
  1794. 1:05:21uh caffeine is not because
  1795. 1:05:24uh I'm so puritanical I want to be the
  1796. 1:05:26poster child of good sleep. I love the
  1797. 1:05:28smell of freshly ground coffee in the
  1798. 1:05:30morning. It's a great ritual. It's just
  1799. 1:05:32that I've read my genetics and I am one
  1800. 1:05:35of the slow caffeine metabolizers. So,
  1801. 1:05:37you can do these genetic kits online and
  1802. 1:05:40they will tell you are you a slow
  1803. 1:05:42metabolizer or a fast metabolizer. So,
  1804. 1:05:44that's the variability. That's why some
  1805. 1:05:46people say, "Look, I'm pretty immune to
  1806. 1:05:48caffeine." And others will say, "No, I'm
  1807. 1:05:49not." Um why do I now favor coffee? I
  1808. 1:05:54was actually quite
  1809. 1:05:56anti-caffeine
  1810. 1:05:58and coffee when I first came out with
  1811. 1:05:59the book, just looking at the studies.
  1812. 1:06:01But now the data is immensely
  1813. 1:06:03compelling. The health benefits
  1814. 1:06:06associated with coffee are undeniable.
  1815. 1:06:09Study after study after study. And we
  1816. 1:06:11can put them all together in this big
  1817. 1:06:13what we call a meta-analysis study. And
  1818. 1:06:15it is so strikingly clear that coffee,
  1819. 1:06:17drinking coffee, is a good thing for you
  1820. 1:06:20from a health perspective.
  1821. 1:06:24Two things to say about that. The first
  1822. 1:06:27is that it's got nothing to do with the
  1823. 1:06:30caffeine.
  1824. 1:06:31And a lot of people have sort of rightly
  1825. 1:06:33challenged me to say, "Look, you say how
  1826. 1:06:36problematic sleep can be when you're
  1827. 1:06:38drinking too much caffeine.
  1828. 1:06:40But yet coffee is associated with many
  1829. 1:06:43of the same health benefits that sleep
  1830. 1:06:45is associated with. But coffee is
  1831. 1:06:48supposed to hurt your sleep. How do you
  1832. 1:06:50reconcile those two, Matt Walker?"
  1833. 1:06:53And the answer is very simple.
  1834. 1:06:56Antioxidants.
  1835. 1:06:58Because it turns out that the coffee
  1836. 1:06:59bean contains a whopping dose of
  1837. 1:07:03antioxidants.
  1838. 1:07:04Things such as
  1839. 1:07:06it's what's other things such as
  1840. 1:07:07cafestol, but it's got a bunch of
  1841. 1:07:10incredible antioxidants. Probably the
  1842. 1:07:12most powerful of them in terms of the
  1843. 1:07:14coffee bean is something called
  1844. 1:07:16chlorogenic acid. Now, don't worry, it's
  1845. 1:07:18not chlorine, it's not chloride, it's
  1846. 1:07:20not bleach. Chlorogenic acid is very
  1847. 1:07:23different.
  1848. 1:07:24And what's happened in the modern world
  1849. 1:07:27is that we
  1850. 1:07:28on we have and struggle with our diet so
  1851. 1:07:32much because we don't eat enough whole
  1852. 1:07:34foods, etc. So, what's happened is that
  1853. 1:07:39the coffee bean has been now asked to
  1854. 1:07:42carry the Herculean weight of all of our
  1855. 1:07:45antioxidant needs on its shoulders.
  1856. 1:07:49And where most people get the majority
  1857. 1:07:51of their antioxidants
  1858. 1:07:53is by way of drinking coffee. That's why
  1859. 1:07:56coffee is associated with so many health
  1860. 1:07:58benefits, and it's not the caffeine.
  1861. 1:08:00Case in point, if you look at the
  1862. 1:08:02studies with decaffeinated coffee, you
  1863. 1:08:04get very similar health benefits.
  1864. 1:08:07Again, it's not the caffeine, it's the
  1865. 1:08:09coffee itself. So,
  1866. 1:08:11the bottom line here is
  1867. 1:08:13drink coffee, but I would say the dose
  1868. 1:08:16and the timing make the poison. So, try
  1869. 1:08:20to limit yourself to about two cups of
  1870. 1:08:23coffee, three cups of coffee maximum,
  1871. 1:08:25because if you look at the health
  1872. 1:08:26benefits, by the way,
  1873. 1:08:27it's a dose it's not a dose response
  1874. 1:08:29where it's linear where the more and
  1875. 1:08:31more coffee you drink, the more and more
  1876. 1:08:32healthy you become. It peaks at about
  1877. 1:08:35two to three, and then actually starts
  1878. 1:08:36to go down in the opposite direction for
  1879. 1:08:39lots of reasons that we can speak about.
  1880. 1:08:40So,
  1881. 1:08:41dose and the timing make the poison when
  1882. 1:08:43it comes to coffee.
  1883. 1:08:44So, you drink decaf?
  1884. 1:08:45So, I do drink decaf. So, I will drink
  1885. 1:08:48coffee just because I love the smell,
  1886. 1:08:49and I do enjoy the taste of it, but I
  1887. 1:08:52drink uh decaffeinated coffee.
  1888. 1:08:54I would love to drink uh caffeinated
  1889. 1:08:57coffee too, cuz I
  1890. 1:08:59you know, I I'm sure
  1891. 1:09:01it would be interesting cuz I work out
  1892. 1:09:02day and I work out every morning and so
  1893. 1:09:04many of the health coaches that I speak
  1894. 1:09:06with and health professionals say, "You
  1895. 1:09:09know, you should definitely get a shot
  1896. 1:09:10of caffeine and it boosts your workout."
  1897. 1:09:12And actually the data on that is pretty
  1898. 1:09:14clear, too, that
  1899. 1:09:15your lifting, for example, in the gym
  1900. 1:09:17and your metabolic activity is stronger
  1901. 1:09:19when you've had pre-caffeine doses.
  1902. 1:09:22But it's also stronger when you sleep.
  1903. 1:09:24But exactly, and that's the problem. So,
  1904. 1:09:27uh and sleep is
  1905. 1:09:28I would argue much more beneficial to
  1906. 1:09:32health and if you're trying to work out
  1907. 1:09:34or you're trying to uh be an athlete or
  1908. 1:09:36perform,
  1909. 1:09:37sleep will trump caffeine five ways till
  1910. 1:09:40Tuesday. I mean, sleep is probably the
  1911. 1:09:43very best legal performance-enhancing
  1912. 1:09:46drug that we know of that not enough
  1913. 1:09:48athletes are abusing.
  1914. 1:09:51As you might know, this show is now
  1915. 1:09:52sponsored by Airbnb. I can't count how
  1916. 1:09:54many times Airbnbs have saved me when
  1917. 1:09:56I'm traveling around the world, whether
  1918. 1:09:57it's, you know, recently when I went to
  1919. 1:09:59the jungle in Bali or whether it's when
  1920. 1:10:00I'm staying here in the UK or going to
  1921. 1:10:02business in America. But I can also
  1922. 1:10:03think of so many times where I've stayed
  1923. 1:10:05in a host's place on Airbnb and I've
  1924. 1:10:07been sat there wondering, "Could my
  1925. 1:10:09place be an Airbnb as well?" And if it
  1926. 1:10:12could be, how much could I earn? It
  1927. 1:10:14turns out you could be sitting on an
  1928. 1:10:17Airbnb goldmine without even knowing
  1929. 1:10:19about it. Maybe you have a a spare room
  1930. 1:10:21in your house that friends stay from
  1931. 1:10:23time to time. You could Airbnb that
  1932. 1:10:25space and make a significant amount of
  1933. 1:10:27money instead of letting it stay empty.
  1934. 1:10:29That in-law, that guest house, that
  1935. 1:10:31annex where your parents sometimes stay,
  1936. 1:10:33you could Airbnb that and make some
  1937. 1:10:35extra income for yourself. Whether you
  1938. 1:10:37could just use some extra money to cover
  1939. 1:10:39some bills or for something a little bit
  1940. 1:10:41more fun, your home might be worth a
  1941. 1:10:44little bit more than you think. And you
  1942. 1:10:46can find out the answer to that question
  1943. 1:10:47by going to airbnb.co.uk/host.
  1944. 1:10:51One of the other sort of ongoing
  1945. 1:10:52stereotypes that I've always wondered if
  1946. 1:10:53it was wrong or right or whatever, now I
  1947. 1:10:55get to a chance to ask you is about this
  1948. 1:10:57culture of sleep medication. So I've got
  1949. 1:11:00some friends who who might have I don't
  1950. 1:11:03know prescribed sleep medication but
  1951. 1:11:04I've got a lot of friends also that use
  1952. 1:11:07what they call sort of natural they
  1953. 1:11:08always use the word natural natural
  1954. 1:11:10something so it's like natural sleep
  1955. 1:11:13tablets.
  1956. 1:11:14What's your perspective on this culture
  1957. 1:11:15of us
  1958. 1:11:17humans taking sleep tablets to get them
  1959. 1:11:20to feel sleepy and go off to sleep at
  1960. 1:11:21night?
  1961. 1:11:22Usually when people ask me that question
  1962. 1:11:24personally I the first thing I ask them
  1963. 1:11:26is why is it that you think you're not
  1964. 1:11:28able to sleep?
  1965. 1:11:30And try to reverse engineer the question
  1966. 1:11:32from there before we even start thinking
  1967. 1:11:34about sticking band-aids on wounds I
  1968. 1:11:37firstly want to ask what's causing the
  1969. 1:11:39infection because we can keep bandaging
  1970. 1:11:42it for all we like but if it keeps
  1971. 1:11:45festering it's probably not going to go
  1972. 1:11:47away anytime soon.
  1973. 1:11:48Is it a problem to keep bandaging it?
  1974. 1:11:50It is a problem. Right now we don't
  1975. 1:11:53typically advocate sleeping pills as the
  1976. 1:11:55first line defense agent against or for
  1977. 1:11:58insomnia as a treatment. In fact in 2016
  1978. 1:12:02the American and again this is me simply
  1979. 1:12:04describing the science. This is me being
  1980. 1:12:07descriptive of the science not
  1981. 1:12:09prescriptive in in terms of medicine cuz
  1982. 1:12:12I'm not a medical doctor.
  1983. 1:12:14Um
  1984. 1:12:15but in 2016 the American College of
  1985. 1:12:18Physicians they had a expert panel who
  1986. 1:12:21surveyed all of the literature on
  1987. 1:12:22classic sleeping pills and what they
  1988. 1:12:25suggested was that sleeping pills must
  1989. 1:12:27no longer be the first line treatment
  1990. 1:12:30for insomnia it has to be cognitive
  1991. 1:12:33behavioral therapy for insomnia or what
  1992. 1:12:34we call CBT-I which is a psychological
  1993. 1:12:37intervention that we can speak about.
  1994. 1:12:39But their recommendation was that they
  1995. 1:12:40found
  1996. 1:12:42I think their wording was um small and
  1997. 1:12:45of questionable clinical importance in
  1998. 1:12:48terms of the benefits of sleeping pills.
  1999. 1:12:50Now
  2000. 1:12:51there is a time and a place
  2001. 1:12:53for in clinical medicine for sleeping
  2002. 1:12:55pills, but usually as an adjunct in
  2003. 1:12:58combination with cognitive behavioral
  2004. 1:13:00therapy.
  2005. 1:13:01They are not advocated for long-term
  2006. 1:13:04use, but so they usually advocated for
  2007. 1:13:06short-term use, weeks.
  2008. 1:13:08Most people have been on them for months
  2009. 1:13:10if not years, these classic sleeping
  2010. 1:13:12pills, and that's a problem
  2011. 1:13:14because those sleeping pills are in a
  2012. 1:13:16class of drugs that we call the sedative
  2013. 1:13:18hypnotics.
  2014. 1:13:20And sedation is not sleep.
  2015. 1:13:23For sub- subset of some people, there
  2016. 1:13:25are some of these {quote} {unquote}
  2017. 1:13:28sleep supplements that may benefit, but
  2018. 1:13:31overall, the studies are very clear.
  2019. 1:13:34None of them are efficacious.
  2020. 1:13:37And when you think about it, it makes
  2021. 1:13:39sense.
  2022. 1:13:40You know, if there was some cheap sleep
  2023. 1:13:42supplement that you could buy on Amazon
  2024. 1:13:44that was the Shangri-La of good sleep,
  2025. 1:13:47that was this miracle sleep drug,
  2026. 1:13:50don't you think that a pharmaceutical
  2027. 1:13:52company would have patented it 20 years
  2028. 1:13:53ago and be making billions of dollars
  2029. 1:13:55from it? You know, that alone tells you
  2030. 1:13:57all that you need to know about, you
  2031. 1:13:59know, these natural sleep supplements.
  2032. 1:14:02Cognitive behavioral therapy for
  2033. 1:14:03insomnia though
  2034. 1:14:04Yeah.
  2035. 1:14:05seems to be the kind of the front line
  2036. 1:14:06of
  2037. 1:14:07prescribed defense against a lack of
  2038. 1:14:09sleep insomnia conditions. What exactly
  2039. 1:14:12is that therapy aiming to do? What like
  2040. 1:14:15what does it do for for somebody?
  2041. 1:14:17Great question. So, in some ways, the
  2042. 1:14:20the title um tries to suggest what it
  2043. 1:14:23what it does, but not particularly well,
  2044. 1:14:24perhaps. So, it focuses on cognitive
  2045. 1:14:28aspects, and it focuses on behavioral
  2046. 1:14:30aspects.
  2047. 1:14:31So, for the cognitive aspects, when we
  2048. 1:14:34do cognitive behavioral therapy working
  2049. 1:14:36with the patient, we'll try to focus on
  2050. 1:14:38thoughts and beliefs and ideas around
  2051. 1:14:41sleep. Do they have anxiety around the
  2052. 1:14:43bedroom? Most of them do.
  2053. 1:14:45I can't sleep.
  2054. 1:14:46Because I can't sleep. So, every time I
  2055. 1:14:48walk into the bedroom, my bed is the
  2056. 1:14:50enemy. And I look at the bedroom and I
  2057. 1:14:52look at the bed, and I just know that
  2058. 1:14:54that means I'm going to have a bad night
  2059. 1:14:56of sleep. So, what's happened is that at
  2060. 1:14:59that point, your sleep controls you.
  2061. 1:15:03And you've lost all confidence in your
  2062. 1:15:05ability to sleep. And we need to course
  2063. 1:15:08correct that. So, one of the things we
  2064. 1:15:09do in cognitive behavioral therapy is
  2065. 1:15:11that we lower that anxiety. And we say,
  2066. 1:15:13"Look, everyone has a bad night of
  2067. 1:15:15sleep, even a bad couple of nights of
  2068. 1:15:17sleep. In fact, I will tell you, I don't
  2069. 1:15:20sleep perfectly well all the time, too.
  2070. 1:15:21I've had at least two very severe bouts
  2071. 1:15:23of insomnia in my life.
  2072. 1:15:26We all have a bad night of sleep. It
  2073. 1:15:28doesn't mean that tomorrow you're going
  2074. 1:15:30to wake up with depression or
  2075. 1:15:32Alzheimer's disease. Don't worry, you're
  2076. 1:15:34not going to get cancer, you know,
  2077. 1:15:36tomorrow, just because you've had a bad
  2078. 1:15:37night of sleep. So, we start to change
  2079. 1:15:39people's misbeliefs about sleep. And we
  2080. 1:15:42try to get them back from being
  2081. 1:15:44catastrophic about this idea of my not
  2082. 1:15:46sleeping.
  2083. 1:15:48So, we That's the cognitive aspect. We
  2084. 1:15:50start to lower their anxiety around the
  2085. 1:15:52bed and and the bedroom. We start to try
  2086. 1:15:55to build confidence back. We start to
  2087. 1:15:57reduce their expectations about, you
  2088. 1:16:00know, what is reasonable sleep? Well,
  2089. 1:16:02right now you're getting 4 or 5 hours of
  2090. 1:16:04sleep, and we can do better. But, don't
  2091. 1:16:07start thinking that you need to get 8
  2092. 1:16:09hours of sleep straight out the box.
  2093. 1:16:11Let's just manage it.
  2094. 1:16:12That's just because it's going to stress
  2095. 1:16:13you out, right?
  2096. 1:16:14It's only going to make my sleep worse.
  2097. 1:16:15Right. Okay.
  2098. 1:16:16You know, when you're struggling with
  2099. 1:16:17sleep in the middle of the night and
  2100. 1:16:18you're wide awake,
  2101. 1:16:20you're laying in bed and you're
  2102. 1:16:20thinking, "Oh my god, I've got 5 hours
  2103. 1:16:22left before I've got to go to work."
  2104. 1:16:23It's terri- It's the last, you know,
  2105. 1:16:25it's a little bit like trying to
  2106. 1:16:26remember someone's name. The harder you
  2107. 1:16:28try, the further you push it away.
  2108. 1:16:31So, would you say in that What What do I
  2109. 1:16:32do in that situation? You It's 2:00 a.m.
  2110. 1:16:34in the morning, you've got to be up at
  2111. 1:16:357:00, there's a flight you're getting
  2112. 1:16:37on, say, whatever.
  2113. 1:16:38Yeah.
  2114. 1:16:38What should one do? Cuz
  2115. 1:16:40from what I was reading in chapter 14, I
  2116. 1:16:42was I was hearing that maybe I should
  2117. 1:16:44get out of bed.
  2118. 1:16:45Or not just sit there and ruminate.
  2119. 1:16:48You know, into the early hours of the
  2120. 1:16:49morning. Or do I stay in bed and do
  2121. 1:16:51something?
  2122. 1:16:52What does one do?
  2123. 1:16:54The prototypical recommendation is that
  2124. 1:16:57after about 30 minutes of time awake,
  2125. 1:16:59you should get out of your bed and you
  2126. 1:17:01should just go to a different room and
  2127. 1:17:02do something like, you know, read a book
  2128. 1:17:05or listen to a podcast. Don't eat cuz it
  2129. 1:17:07then trains your brain to wake up to do
  2130. 1:17:10that. Don't start working or getting in
  2131. 1:17:12front of a computer screen, you know. I
  2132. 1:17:14said listen to a podcast, sure, you
  2133. 1:17:16know, just make sure your phone's in you
  2134. 1:17:18know, you don't start scrolling anymore
  2135. 1:17:19than that. But you can do relaxing
  2136. 1:17:21things, stretch, meditate.
  2137. 1:17:24The reason is because if you start to
  2138. 1:17:26spend a lot of time awake in your bed,
  2139. 1:17:28your brain is an incredibly associative
  2140. 1:17:30device. And very quickly, it will start
  2141. 1:17:32to learn that this thing called your bed
  2142. 1:17:34is this place where I'm always awake.
  2143. 1:17:37And therefore, you start to learn
  2144. 1:17:39through this
  2145. 1:17:40repeated loop of behavior that I'm
  2146. 1:17:43always going to be wide awake in bed.
  2147. 1:17:44And we need to break that association,
  2148. 1:17:46and that's why we say get out of bed
  2149. 1:17:48after about 30 minutes, cuz you're just
  2150. 1:17:49training your brain to think that this
  2151. 1:17:51thing called my bed is the place where
  2152. 1:17:53I'm never asleep. And we want to break
  2153. 1:17:55that.
  2154. 1:17:56And only return to bed when you're
  2155. 1:17:58sleepy, and there's no time limit for
  2156. 1:17:59that. And that way, gradually, it's much
  2157. 1:18:02better because you will relearn the
  2158. 1:18:03association that your bed, just as when
  2159. 1:18:05you were young, was guaranteed that your
  2160. 1:18:07bed is this place where you will always
  2161. 1:18:09be asleep.
  2162. 1:18:10The problem with that is many people
  2163. 1:18:12don't want, you know, it's the middle of
  2164. 1:18:13the night, it's dark, it's cold. I I'm
  2165. 1:18:16not I'm just not going to get out of
  2166. 1:18:17bed. So, what's your other what what
  2167. 1:18:20else have you got in your toolbox, Matt?
  2168. 1:18:23Um
  2169. 1:18:23at that point, I would say, "Okay,
  2170. 1:18:25that's reasonable."
  2171. 1:18:27The first thing I would suggest is
  2172. 1:18:28meditation.
  2173. 1:18:29You know, I am a hard-nosed scientist,
  2174. 1:18:31and when I was researching that the
  2175. 1:18:34book,
  2176. 1:18:35I was, you know, I just thought this
  2177. 1:18:37sounds all a bit woo-woo and you know, I
  2178. 1:18:39I live and work in Berkeley, California,
  2179. 1:18:42which is kind of, you know, the free
  2180. 1:18:44speech, you know, flower power movement,
  2181. 1:18:46San Francisco, flowers in your hair
  2182. 1:18:47business. I just thought this is all a
  2183. 1:18:49bit, you know,
  2184. 1:18:51holding hands and singing Kumbaya. This
  2185. 1:18:53is This is not for me, this this
  2186. 1:18:55meditation stuff. I couldn't get away
  2187. 1:18:57from the strength of the data. It was
  2188. 1:18:59immensely powerful regarding sleep and
  2189. 1:19:01its benefits on insomnia and sleep. So,
  2190. 1:19:04I started meditating and now I meditate
  2191. 1:19:09for 10 minutes before bed every single
  2192. 1:19:11night and I've been doing that for about
  2193. 1:19:134 years. So, I would say if even if it's
  2194. 1:19:16in the middle of the night and if I wake
  2195. 1:19:17up in the middle of the night, I'll
  2196. 1:19:18start try to walk myself through a
  2197. 1:19:20meditation.
  2198. 1:19:21Um
  2199. 1:19:22You You referenced there
  2200. 1:19:24listening to podcasts, etc., etc. You
  2201. 1:19:26know, doing something else to stimulate
  2202. 1:19:27the brain. I when I go to bed, I have to
  2203. 1:19:30have something playing. I say have to. I
  2204. 1:19:31shouldn't be that definitive. I like to
  2205. 1:19:34have something playing, some kind of
  2206. 1:19:36sound or noise, whatever. And much to my
  2207. 1:19:39partner's dismay,
  2208. 1:19:41my
  2209. 1:19:42content of preference is
  2210. 1:19:45serial killer
  2211. 1:19:48podcasts or documentaries or just like
  2212. 1:19:50something which is really going to grab
  2213. 1:19:52hold of my brain and focus me. So,
  2214. 1:19:55something like It has to be really
  2215. 1:19:57interesting to me for me to be able to
  2216. 1:19:58focus on it. My partner is the opposite
  2217. 1:20:00again. She likes um
  2218. 1:20:03silence.
  2219. 1:20:04Why do I listen to serial killers?
  2220. 1:20:08It's different for different people's
  2221. 1:20:09constitutions, you know, and
  2222. 1:20:11psychologies.
  2223. 1:20:13Uh and you know, I can pathologize you
  2224. 1:20:15all you like if if you would wish me to,
  2225. 1:20:17but I would say it
  2226. 1:20:19what's fundamentally going on here with
  2227. 1:20:21meditation and I'll come back to an
  2228. 1:20:23alternative, too, but the reason why
  2229. 1:20:26some meditation apps as well have now
  2230. 1:20:28started to do what's called sleep
  2231. 1:20:30stories, which in some ways is what
  2232. 1:20:32you're doing a version of with your
  2233. 1:20:34podcast,
  2234. 1:20:36is hark back to when we were kids. You
  2235. 1:20:38know,
  2236. 1:20:40for many parents, they would just read a
  2237. 1:20:41book to the kid. You know, the
  2238. 1:20:43children's books, good night books.
  2239. 1:20:45Because you would read the child to
  2240. 1:20:47sleep.
  2241. 1:20:48And for some reason,
  2242. 1:20:51we as we developed into adults, we
  2243. 1:20:53thought, well, we no longer benefit from
  2244. 1:20:56having a story read to us to help us
  2245. 1:20:57sleep.
  2246. 1:20:58No, it's not true. We
  2247. 1:21:00we benefit hugely. In fact, the the
  2248. 1:21:02meditation company Calm, you know, was
  2249. 1:21:05saved by the introduction of sleep
  2250. 1:21:08stories into their app. They were doing
  2251. 1:21:09pretty well as a meditation app, but
  2252. 1:21:11then they started to do sleep stories
  2253. 1:21:13and it became a unicorn company um in
  2254. 1:21:16terms of its valuation. It broke a
  2255. 1:21:18billion dollars.
  2256. 1:21:20And it was on the
  2257. 1:21:21the back of sleep stories.
  2258. 1:21:23And what they realized is that people
  2259. 1:21:25were self-medicating their insomnia by
  2260. 1:21:27way of meditation.
  2261. 1:21:29So, they latched onto that and then they
  2262. 1:21:31found that these stories, sleep stories,
  2263. 1:21:33were great. And you've got now wonderful
  2264. 1:21:35people, people who you've interviewed on
  2265. 1:21:36the show. So, what you're doing and what
  2266. 1:21:39those sleep stories are doing and what
  2267. 1:21:41meditation is doing, it's all the same
  2268. 1:21:43thing,
  2269. 1:21:44which is that it is taking your mind off
  2270. 1:21:47itself.
  2271. 1:21:49Because when you are struggling to sleep
  2272. 1:21:51or you've woken up in the middle of the
  2273. 1:21:53night,
  2274. 1:21:54what you don't want to be doing is
  2275. 1:21:56focusing on either what you
  2276. 1:21:59what you What did I do today? What did I
  2277. 1:22:02not do today? What did I do poorly? Oh
  2278. 1:22:04my goodness, what have I still got to do
  2279. 1:22:05tomorrow? And at that point, things are
  2280. 1:22:08just a disaster. You're wide awake.
  2281. 1:22:12What all of the things that we've just
  2282. 1:22:14discussed do is they take your mind off
  2283. 1:22:17itself.
  2284. 1:22:18And at that point, then you start to
  2285. 1:22:21allow sleep to come back naturally.
  2286. 1:22:24That's why one of the other suggestions
  2287. 1:22:26is take yourself for a mental walk.
  2288. 1:22:28So, don't count sheep, by the way, that
  2289. 1:22:30doesn't work. A colleague of mine at UC
  2290. 1:22:32Berkeley did the study. Actually, takes
  2291. 1:22:34you longer to fall asleep if you're
  2292. 1:22:35counting uh sheep. What she found that
  2293. 1:22:38the Dr. Allison Harvey was that if you
  2294. 1:22:40just close your eyes and you think about
  2295. 1:22:42a walk that you take frequently, let's
  2296. 1:22:44say it's a walk with the dog,
  2297. 1:22:46and you think about it in high-fidelity
  2298. 1:22:48detail. So, I close my eyes, I go out
  2299. 1:22:51the door, take a left down the steps,
  2300. 1:22:53then I'm going to go up the street, I
  2301. 1:22:54take the first left past that pine tree.
  2302. 1:22:57That's the level of detail. If you just
  2303. 1:22:59walk yourself on that mental walk, sure
  2304. 1:23:01enough, people fall asleep in about 50%
  2305. 1:23:04less time, half the time it takes.
  2306. 1:23:06This is the thing with sleep stories and
  2307. 1:23:07also my serial killer documentaries or
  2308. 1:23:10serial killer podcasts that I listen to.
  2309. 1:23:12Detail.
  2310. 1:23:13Exactly.
  2311. 1:23:14You get even I've listened to
  2312. 1:23:16Calm's sleep stories before, and the
  2313. 1:23:19attention to detail in the sort of
  2314. 1:23:21descriptive nature of what they're
  2315. 1:23:22saying is so apparent. They'll say
  2316. 1:23:24things like,
  2317. 1:23:25"The cold, wet window sill saw the
  2318. 1:23:28raindrops like
  2319. 1:23:30um tapping against it one by one by one
  2320. 1:23:34by one." And that sounds very similar to
  2321. 1:23:36my serial killer documentaries when I
  2322. 1:23:37hear about the serial killer coming in
  2323. 1:23:38through the window.
  2324. 1:23:39Yeah. Yeah. Yeah.
  2325. 1:23:40At night time. Um
  2326. 1:23:42and I wondered why the descriptive
  2327. 1:23:44nature of it, the detail matters for
  2328. 1:23:46dozing us off.
  2329. 1:23:47And because it prevent I mean, you've
  2330. 1:23:49got limited bandwidth in terms of
  2331. 1:23:50cognitive capacity.
  2332. 1:23:51Right.
  2333. 1:23:52And if you're consumed and you saturate
  2334. 1:23:54your bandwidth with that level of
  2335. 1:23:56detail, it's very hard for any of these
  2336. 1:23:58other things called our worries and our
  2337. 1:24:00anxieties to start entering into our
  2338. 1:24:03mind. The other thing I would note, by
  2339. 1:24:04the way, though, is
  2340. 1:24:06if you are if none of these things are
  2341. 1:24:08working for you, if the fictional notion
  2342. 1:24:11of serial killing is not working for
  2343. 1:24:13you, if meditation is not working for
  2344. 1:24:15you, if going on a mental walk is not
  2345. 1:24:18working for you,
  2346. 1:24:20this is the final suggestion I have. If
  2347. 1:24:21you're lying there awake, firstly, by
  2348. 1:24:24the way, if you're struggling with
  2349. 1:24:25sleep, remove all clock faces from your
  2350. 1:24:27bedroom. It's one of the best pieces of
  2351. 1:24:29advice I can give you.
  2352. 1:24:30Knowing what time of night it is is no
  2353. 1:24:33favor.
  2354. 1:24:34So, knowing now that it's 3:23 a.m. in
  2355. 1:24:38the morning and I'm still struggling to
  2356. 1:24:40fall asleep, and then I look back at the
  2357. 1:24:41clock and it's now 4:03 a.m. and I've
  2358. 1:24:44still been awake, and now it's 4:27 and
  2359. 1:24:47I've got to wake up at 6:30 a.m. Knowing
  2360. 1:24:50that
  2361. 1:24:51has no utility for you. Remove all clock
  2362. 1:24:55faces from your bedroom. It is a gift.
  2363. 1:24:58But, coming back to the final
  2364. 1:25:00suggestion, if you don't want to get out
  2365. 1:25:02of bed, if you don't want to listen to a
  2366. 1:25:03podcast,
  2367. 1:25:05the final thing I would say is just
  2368. 1:25:07accept and say, "Look, it's okay.
  2369. 1:25:09Tonight is not my night. It is not the
  2370. 1:25:12worst thing in the world. And instead of
  2371. 1:25:15trying to sleep, all I'm going to do
  2372. 1:25:17here is lie in bed,
  2373. 1:25:19and I'm just going to rest."
  2374. 1:25:22Because wouldn't it be lovely if someone
  2375. 1:25:24came to you in the middle of your work
  2376. 1:25:25day,
  2377. 1:25:26you're just stressed and someone said,
  2378. 1:25:28"By the way, just come into this room.
  2379. 1:25:30There's a There's a bed here. Just lie
  2380. 1:25:32down and just rest for an hour."
  2381. 1:25:35Wouldn't it be lovely? Just have a good
  2382. 1:25:36old rest for an an hour. Just rest
  2383. 1:25:39there.
  2384. 1:25:41And I would say that if you can't sleep,
  2385. 1:25:43just lie in bed, stop worrying about
  2386. 1:25:45sleep and not being able to get it, stop
  2387. 1:25:47worrying about the next day, just lie in
  2388. 1:25:49there and enjoy a nice good old rest.
  2389. 1:25:54And by the way, usually what happens is
  2390. 1:25:56that after you start thinking, "Okay,
  2391. 1:25:58I'm going to rest," the next thing you
  2392. 1:25:59remember is the alarm clock going off at
  2393. 1:26:016:30 because finally you stopped trying
  2394. 1:26:04and sleep happened. So, yeah.
  2395. 1:26:05Of course. You know, prolonged one of
  2396. 1:26:08the things I've also I wonder if this is
  2397. 1:26:09a if I'm wrong about this is I sometimes
  2398. 1:26:13thought that, you know, I could go
  2399. 1:26:14Monday to Friday and kind of sacrifice
  2400. 1:26:16my sleep. This was specifically when I
  2401. 1:26:18was really in the height of like running
  2402. 1:26:19big businesses, etc.
  2403. 1:26:21Um and then on the weekend I'll just
  2404. 1:26:22make up for it.
  2405. 1:26:24So I thought, you know, I could go
  2406. 1:26:25Monday to Friday, I'll sleep maybe
  2407. 1:26:26sometimes 2 hours a night, 3 hours a
  2408. 1:26:28night, whatever. Then Saturday, you
  2409. 1:26:29know, I'll just do a, you know, 11-hour
  2410. 1:26:32sleeping and I'll just make up for it.
  2411. 1:26:33Yeah.
  2412. 1:26:36Is that a good strategy?
  2413. 1:26:39The delightful laughter at the end of
  2414. 1:26:41your sentence that uh
  2415. 1:26:43I think probably tells you the answer
  2416. 1:26:44that you know. Um
  2417. 1:26:46unfortunately, sleep doesn't work like
  2418. 1:26:49that. It would be nice if it did. Sleep
  2419. 1:26:51is not like the bank. In other words,
  2420. 1:26:53you can't accumulate a debt
  2421. 1:26:56as you were doing during the week and
  2422. 1:26:57then hope to try and pay it off
  2423. 1:27:00at the weekend.
  2424. 1:27:01Um
  2425. 1:27:02So for example, let me take an extreme
  2426. 1:27:04version of that experiment. Let me take
  2427. 1:27:06you tonight. I'm going to deprive you of
  2428. 1:27:08sleep for an entire night for, let's
  2429. 1:27:10say, 8 hours of sleep. And then tomorrow
  2430. 1:27:12night I'm going to give you all of the
  2431. 1:27:14recovery sleep that you want, as much as
  2432. 1:27:16you wish for. And then the next night
  2433. 1:27:18you can have all of the recovery sleep
  2434. 1:27:21that you want. And even on the third
  2435. 1:27:22night,
  2436. 1:27:23will you sleep longer that first
  2437. 1:27:26recovery night after a night of no
  2438. 1:27:28sleep? Absolutely, you will sleep
  2439. 1:27:30longer.
  2440. 1:27:32But across those three or four recovery
  2441. 1:27:33nights of sleep, will you get back all
  2442. 1:27:36of the sleep that you lost? Not even
  2443. 1:27:37close. You'll maybe only sleep back
  2444. 1:27:39about four, four and a half of the 8
  2445. 1:27:42hours that you lost. In other words, by
  2446. 1:27:45that stage, you are four or three and a
  2447. 1:27:47half hours in overdraft on your sleep
  2448. 1:27:51bank account. You went into debt and you
  2449. 1:27:53only paid about 50% of it back. So
  2450. 1:27:56what's happening with you during the
  2451. 1:27:58week is that you're accumulating this
  2452. 1:28:00debt,
  2453. 1:28:01you know, of maybe 10 hours. You're
  2454. 1:28:03short-changing, you're only sleeping
  2455. 1:28:04like 6 hours a night for the five nights
  2456. 1:28:07during the week. And then you binge on
  2457. 1:28:09sleep and you try to maybe sleep 10
  2458. 1:28:11hours or 11 hours, that's only two or
  2459. 1:28:14three extra hours. So, sum total that's
  2460. 1:28:17only four to six, you know, hours of
  2461. 1:28:21made-up sleep
  2462. 1:28:23relative to the 10 hours of debt. So,
  2463. 1:28:25what happens is that that next week, you
  2464. 1:28:27now carry forward four hours of your
  2465. 1:28:30debt.
  2466. 1:28:31And then next weekend, you try to sleep
  2467. 1:28:34it back, but you're still four hours
  2468. 1:28:35lost. So, now you've got eight hours of
  2469. 1:28:37net debt. In other words, what it
  2470. 1:28:39develops is into a compounding interest
  2471. 1:28:41on a loan. It just starts to escalate
  2472. 1:28:43ballistically across weeks, across
  2473. 1:28:45years, and across the lifespan.
  2474. 1:28:47And then what happens in terms of
  2475. 1:28:50health outcomes? So, say that I did that
  2476. 1:28:52for a couple of years. Say that I
  2477. 1:28:53sustained that pattern of, you know,
  2478. 1:28:55depriving myself of sleep throughout the
  2479. 1:28:56week, maybe catch up on Saturday,
  2480. 1:28:58Yeah.
  2481. 1:28:58depriving myself again the next week,
  2482. 1:29:00catch up on Sunday, deprive myself the
  2483. 1:29:02next week, and I did that pattern for
  2484. 1:29:04multiple years. What would What would be
  2485. 1:29:06the health implications?
  2486. 1:29:08So, you can describe them short, mid,
  2487. 1:29:12and long-term.
  2488. 1:29:14The first thing I would say though is
  2489. 1:29:15that the elastic band of sleep
  2490. 1:29:16deprivation will stretch only so far
  2491. 1:29:18before it snaps.
  2492. 1:29:20The short-term,
  2493. 1:29:22you know, probably the most immediate
  2494. 1:29:23short-term consequence is that you are
  2495. 1:29:26popped out in a driving-related
  2496. 1:29:28accident, drowsy-related accident.
  2497. 1:29:32Because drowsy-related accidents are
  2498. 1:29:34non-trivial. They make up a large
  2499. 1:29:37proportion of accidents on our streets
  2500. 1:29:40in terms of human error-full driving.
  2501. 1:29:42When you say popped out
  2502. 1:29:44out of the gene pool.
  2503. 1:29:46Okay. So, what happens is that when you
  2504. 1:29:48are under-slept, you're at the wheel and
  2505. 1:29:50you start to have what we call
  2506. 1:29:51microsleeps,
  2507. 1:29:53where your eyelid will partially close.
  2508. 1:29:55Now, you are not aware of it. You have
  2509. 1:29:57no awareness of it whatsoever. And in
  2510. 1:29:59fact, parts of your brain seem as though
  2511. 1:30:01they're almost falling asleep. Like
  2512. 1:30:03you're having this microsleep, and it
  2513. 1:30:04lasts for about a second or two seconds.
  2514. 1:30:07Now, if you're on the motorway and
  2515. 1:30:08you're traveling at 70 mph
  2516. 1:30:10and you have a 2-second microsleep,
  2517. 1:30:13that's enough time for you to drift from
  2518. 1:30:15one lane into the next. If you're just
  2519. 1:30:17in a two on a two-lane, you know, sort
  2520. 1:30:20of
  2521. 1:30:21backstreet
  2522. 1:30:22where there's oncoming traffic in the
  2523. 1:30:24other direction
  2524. 1:30:25and you're traveling at 40 mph and you
  2525. 1:30:27drift halfway into that lane,
  2526. 1:30:30that's oncoming traffic. So,
  2527. 1:30:32in other words, if you have a microsleep
  2528. 1:30:34at 60 or 70 mph, at that point there's a
  2529. 1:30:382-ton missile traveling at 60 mph and no
  2530. 1:30:41one's in control.
  2531. 1:30:42And that may be the last microsleep that
  2532. 1:30:44you ever have in your life.
  2533. 1:30:46Obviously, all the other things you've
  2534. 1:30:48mentioned would be implications, things
  2535. 1:30:49like performance drop, and sort of
  2536. 1:30:51memory, relationships, libido would all
  2537. 1:30:54drop off. So, I wouldn't be having as
  2538. 1:30:55much sex, I wouldn't you wouldn't have
  2539. 1:30:56all those things. Then mid-term.
  2540. 1:30:58So, mid-term, then you're going to
  2541. 1:30:59escalate those things into more disease
  2542. 1:31:01state. So, for example, if I were to
  2543. 1:31:03take an individual and people have done
  2544. 1:31:05these studies, not not we, but um where
  2545. 1:31:07you limit them to let's say 4 or 5 hours
  2546. 1:31:09of sleep for 1 week,
  2547. 1:31:11your levels of blood sugar are disrupted
  2548. 1:31:14so significantly that your doctor at the
  2549. 1:31:17end of that 1 week would classify you as
  2550. 1:31:19being pre-diabetic.
  2551. 1:31:21So, that's you could almost argue that
  2552. 1:31:23short-term, not mid-term.
  2553. 1:31:25Mhm. Yeah.
  2554. 1:31:25Um you know, one if you're a male and I
  2555. 1:31:29limit you to 4 or 5 hours of sleep, a
  2556. 1:31:31healthy young male,
  2557. 1:31:33um for 1 week, I will drop your levels
  2558. 1:31:36of testosterone to that of someone who
  2559. 1:31:38is 10 years older than you. So, I can
  2560. 1:31:40age you by a decade just by short
  2561. 1:31:43sleeping you for 1 week. We see
  2562. 1:31:46equivalent impairments in female
  2563. 1:31:47reproductive health in estrogen,
  2564. 1:31:49luteinizing hormone, and
  2565. 1:31:50follicle-stimulating hormone.
  2566. 1:31:52Um so, it's both men and women.
  2567. 1:31:55Your blood pressure will start to creep
  2568. 1:31:57up, your systolic blood pressure in
  2569. 1:31:59particular will creep up. Your heart
  2570. 1:32:01rate in terms of its um contraction
  2571. 1:32:03rate. In other words, your the the speed
  2572. 1:32:05of your heart starts to increase.
  2573. 1:32:07The progression into obesity, diabetes,
  2574. 1:32:10cardiovascular disease, mental health
  2575. 1:32:13issues, anxiety, depression,
  2576. 1:32:15suicidality,
  2577. 1:32:17all of these things, immune compromise,
  2578. 1:32:19infection.
  2579. 1:32:21All of those things can be termed, you
  2580. 1:32:23know, will be mid-term. Now, all of
  2581. 1:32:25those things have a longer-term tail to
  2582. 1:32:27them, which is this thing called
  2583. 1:32:29premature mortality. So, using that
  2584. 1:32:31sweet spot of 7 to 9 hours of sleep, you
  2585. 1:32:34can argue that there's a simple truth on
  2586. 1:32:36the basis of the data. The shorter your
  2587. 1:32:38sleep, the shorter your life. That short
  2588. 1:32:40sleep will predict or cause mortality.
  2589. 1:32:43Is that supported by the by data?
  2590. 1:32:44That's supported by data, yeah. Now,
  2591. 1:32:46there's an interesting change there,
  2592. 1:32:48which is once you get past about 9 or 10
  2593. 1:32:50hours, your mortality risk doesn't just
  2594. 1:32:52keep going down and down. It will hook
  2595. 1:32:54back up again, as if almost too much
  2596. 1:32:57sleep is a bad thing, and we can explain
  2597. 1:32:59why that is the case as well, and why
  2598. 1:33:01it's probably not quite as simple as
  2599. 1:33:03that. But, the final long-term
  2600. 1:33:05consequence that I would say is
  2601. 1:33:07Alzheimer's disease. You know, the two
  2602. 1:33:09most feared diseases in developed
  2603. 1:33:10nations are cancer and Alzheimer's
  2604. 1:33:12disease. Both of them have links to
  2605. 1:33:14insufficient sleep, many of them causal.
  2606. 1:33:17And this relationship between sleep and
  2607. 1:33:19Alzheimer's disease, this is where we
  2608. 1:33:20actually do, I'd probably say almost 50%
  2609. 1:33:23of the work that I do at my sleep center
  2610. 1:33:24is focused on sleep and Alzheimer's
  2611. 1:33:26disease.
  2612. 1:33:27And there, the data is stunning, I would
  2613. 1:33:29say.
  2614. 1:33:30At this stage, insufficient sleep seems
  2615. 1:33:32to be one of the more or one of the most
  2616. 1:33:37significant lifestyle factors that can
  2617. 1:33:40develop or dictate the development of
  2618. 1:33:43Alzheimer's disease later in life. Now,
  2619. 1:33:45that's a lifestyle factor. There are
  2620. 1:33:47other genetic factors, but certainly we
  2621. 1:33:49now know that it's not just that
  2622. 1:33:51insufficient sleep
  2623. 1:33:53predicts a greater amount of Alzheimer's
  2624. 1:33:57pathology in your brain. So, for
  2625. 1:33:58example, people who on average are
  2626. 1:34:00sleeping 6 hours or less have a far
  2627. 1:34:02higher magnitude of amyloid of beta
  2628. 1:34:06amyloid, which is the sticky toxic
  2629. 1:34:07protein related to Alzheimer's disease,
  2630. 1:34:09and another protein called tau protein.
  2631. 1:34:11These are the two protein culprits of
  2632. 1:34:13Alzheimer's. Both of those are escalate
  2633. 1:34:17the less and less sleep that you have.
  2634. 1:34:18Now, that's just associational. We also
  2635. 1:34:20know, by the way, that two sleep
  2636. 1:34:21disorders, insomnia and sleep apnea,
  2637. 1:34:23heavy snoring, both of those are
  2638. 1:34:25associated with a marked increased risk
  2639. 1:34:28of your Alzheimer's disease of
  2640. 1:34:30Alzheimer's disease later in life.
  2641. 1:34:32That's simply associational. That
  2642. 1:34:33doesn't prove causality, but we now have
  2643. 1:34:36the causal evidence both in animal
  2644. 1:34:38models and in human models. If I deprive
  2645. 1:34:41a human being of sleep for single night,
  2646. 1:34:43or I even just deprive you of deep sleep
  2647. 1:34:46for a single night, the next day we can
  2648. 1:34:48see an immediate increase in these
  2649. 1:34:50Alzheimer's disease-related proteins
  2650. 1:34:52circulating in your bloodstream,
  2651. 1:34:54circulating in what we call a
  2652. 1:34:56cerebrospinal fluid that bathes the
  2653. 1:34:58brain, and using special brain scans, we
  2654. 1:35:00can even measure it within the brain
  2655. 1:35:02itself.
  2656. 1:35:04So, these are causal manipulations. It's
  2657. 1:35:06not associational. I manipulate this
  2658. 1:35:08thing called sleep, and the consequence
  2659. 1:35:10is that I manipulate your Alzheimer's
  2660. 1:35:12disease proteins.
  2661. 1:35:14That's correlation going to causation.
  2662. 1:35:16Then the question is, well, mechanism.
  2663. 1:35:20What is it about sleep when you get it
  2664. 1:35:22that is de-escalating Alzheimer's
  2665. 1:35:24disease risk?
  2666. 1:35:25In other words, when you don't get it,
  2667. 1:35:28what why would it increase your
  2668. 1:35:29Alzheimer's risk? And this is a stunning
  2669. 1:35:31discovery made by a scientist called
  2670. 1:35:33Maiken Nedergaard at the University of
  2671. 1:35:35Rochester here in America.
  2672. 1:35:37And she found three things. First,
  2673. 1:35:39studying mice and rats, she found that
  2674. 1:35:42the brain has a cleansing system. Now,
  2675. 1:35:45we didn't used to think that your brain
  2676. 1:35:47had a cleansing system. Your body had
  2677. 1:35:49one, and everyone knows what it's
  2678. 1:35:51called. It's called the lymphatic
  2679. 1:35:53system.
  2680. 1:35:54Um we didn't think the brain had one,
  2681. 1:35:56but she discovered that the brain has
  2682. 1:35:57one. It's called the glymphatic system,
  2683. 1:36:00named after these glial cells that make
  2684. 1:36:02it up.
  2685. 1:36:03The second thing that she discovered is
  2686. 1:36:04that that cleansing system within the
  2687. 1:36:07brain is not always switched on in high
  2688. 1:36:10flow volume across the 24-hour period.
  2689. 1:36:13It was expressly during sleep and
  2690. 1:36:15particularly during deep non-REM sleep
  2691. 1:36:18when that sort of sewage system was put
  2692. 1:36:21into overdrive and washed away all of
  2693. 1:36:24this detritus that built up during the
  2694. 1:36:26day.
  2695. 1:36:27And the final thing that she discovered,
  2696. 1:36:30and this is why it's related to
  2697. 1:36:31Alzheimer's disease, is that two of the
  2698. 1:36:33metabolic byproducts that build up
  2699. 1:36:35during the day in our brain
  2700. 1:36:37are beta amyloid and tau protein,
  2701. 1:36:40the two bad actors in Alzheimer's
  2702. 1:36:43disease.
  2703. 1:36:44So, in other words, what she discovered
  2704. 1:36:45is a system of, you know, good night
  2705. 1:36:47sleep clean. That sleep is a power
  2706. 1:36:50cleanse for the brain.
  2707. 1:36:52And if you're not getting your sleep
  2708. 1:36:53every night, you know, it doesn't mean
  2709. 1:36:55that you're going to get Alzheimer's
  2710. 1:36:57disease next week. It doesn't mean that
  2711. 1:36:58you're going to get Alzheimer's disease,
  2712. 1:36:59you know, in a year's time.
  2713. 1:37:01But night after night, once again, it's
  2714. 1:37:04like compounding interest on a loan.
  2715. 1:37:06And that's why we now believe through
  2716. 1:37:08this causal mechanism that insufficient
  2717. 1:37:10sleep is a risk factor for Alzheimer's
  2718. 1:37:12disease.
  2719. 1:37:13Lots of people will say to me, "Look,
  2720. 1:37:15there are these individuals in society
  2721. 1:37:17who claim that they, you know, didn't
  2722. 1:37:21very much sleep, who didn't sleep a
  2723. 1:37:22lot." You know, Margaret Thatcher is
  2724. 1:37:24often quoted me uh quoted to me about
  2725. 1:37:26that. You know, um
  2726. 1:37:29uh Ronald Reagan was apparently another
  2727. 1:37:31short sleeper.
  2728. 1:37:33I don't think it's coincidental that
  2729. 1:37:35both Thatcher and Reagan went on to die
  2730. 1:37:39of the unfortunate disease of
  2731. 1:37:42Alzheimer's.
  2732. 1:37:45I'm I'm sold.
  2733. 1:37:47Sleep is important, I get it.
  2734. 1:37:49I'm sold.
  2735. 1:37:51How do I
  2736. 1:37:53My question is, what are the things that
  2737. 1:37:56in the modern society are standing in
  2738. 1:37:58the way of sleep? We've touched on some
  2739. 1:38:00of them loosely, but some of the like
  2740. 1:38:01big obvious things, the things that you
  2741. 1:38:03would suggest doing, very actionable
  2742. 1:38:05things we could do straight away to
  2743. 1:38:07improve our chances of having that
  2744. 1:38:09healthy
  2745. 1:38:11deep sleep that we need to be optimal in
  2746. 1:38:14every regard of our health and
  2747. 1:38:15performance.
  2748. 1:38:16There's probably, I think, five standard
  2749. 1:38:19tips, what we call sort of sleep
  2750. 1:38:21hygiene, that you can do. And then I'll
  2751. 1:38:22come on to maybe just some
  2752. 1:38:23unconventional tips that we've sort of
  2753. 1:38:26touched on. And we've spoken about many
  2754. 1:38:28of these. The first thing I would
  2755. 1:38:29recommend people to do, and this is why
  2756. 1:38:31when some people say, "How What about
  2757. 1:38:33this new sleep supplement?" Or, you
  2758. 1:38:35know, it's it's 40 quid for this bottle
  2759. 1:38:37of these sleep
  2760. 1:38:38new sleep natural medications, so I'm
  2761. 1:38:40going to give it a try. I would say, try
  2762. 1:38:42these tried-and-true things first before
  2763. 1:38:45you spend your money on supplements. The
  2764. 1:38:47first thing is regularity.
  2765. 1:38:49Go to bed at the same time and wake up
  2766. 1:38:51at the same time, no matter whether it's
  2767. 1:38:52the weekday or the weekend.
  2768. 1:38:54Your brain expects regularity. It
  2769. 1:38:57thrives best under conditions of
  2770. 1:38:58regularity. When you give it regularity,
  2771. 1:39:01you can improve the quantity and the
  2772. 1:39:03quality of your sleep.
  2773. 1:39:05The second thing is get some darkness at
  2774. 1:39:08night. As I said, we don't get enough
  2775. 1:39:09darkness in the modern world.
  2776. 1:39:12And so, the trick I would offer, and I
  2777. 1:39:15don't use it I don't like the word hack,
  2778. 1:39:16but the sort of suggestion would be in
  2779. 1:39:19the last hour before bed,
  2780. 1:39:22try this experiment for everyone
  2781. 1:39:23listening for the next week,
  2782. 1:39:26dim down half of the lights or switch
  2783. 1:39:28off half of the lights, or even a
  2784. 1:39:30three-quarters of the lights in your
  2785. 1:39:32home in the last hour before bed.
  2786. 1:39:35All of the lights in every room?
  2787. 1:39:36In all of the rooms, you know, switch
  2788. 1:39:39off almost all of the light. Now, I'm
  2789. 1:39:41not suggesting be unsafe and walk around
  2790. 1:39:43in the darkness in the last hour. That's
  2791. 1:39:44not what I'm saying. Just dimmed out,
  2792. 1:39:46you know, switch off half of the lights.
  2793. 1:39:49You will be surprised at how sleepy that
  2794. 1:39:52darkness will make you feel. And it's
  2795. 1:39:54also an incredible behavioral trigger
  2796. 1:39:58to
  2797. 1:40:00signal to your brain that it is time for
  2798. 1:40:04sleep, that darkness is around me.
  2799. 1:40:06That's the second tip is darkness. The
  2800. 1:40:08third tip tip is temperature.
  2801. 1:40:11Most people sleep in an ambient bedroom
  2802. 1:40:13temperature that is too high.
  2803. 1:40:15And you need to aim for a bedroom
  2804. 1:40:17temperature of about 18 18 and 1/2
  2805. 1:40:20degrees Celsius or around about 65 to 68
  2806. 1:40:23degrees Fahrenheit if I'm I'm probably
  2807. 1:40:25butchering the the mathematics there on
  2808. 1:40:27that, but um
  2809. 1:40:29you need to get cool. Now, you can wear
  2810. 1:40:31thick socks, you can have a hot water
  2811. 1:40:32bottle. That's fine, but the ambient
  2812. 1:40:35needs to be cold.
  2813. 1:40:37Because you need to drop your core body
  2814. 1:40:39temperature and your brain temperature
  2815. 1:40:41by about 1 degree Celsius to fall asleep
  2816. 1:40:43and stay asleep.
  2817. 1:40:44And it's the reason that you will always
  2818. 1:40:46find it easier to fall asleep in a room
  2819. 1:40:48that's too cold than too hot.
  2820. 1:40:50So, make your bedroom cold. Make it dark
  2821. 1:40:53like cave.
  2822. 1:40:54The the fourth question would be sort of
  2823. 1:40:58what we've or fourth suggestion would be
  2824. 1:41:01walk it out and we've spoken about this,
  2825. 1:41:03the 30-minute rule, you know, get up, do
  2826. 1:41:05something different or meditate,
  2827. 1:41:07you know, don't lie in bed awake for too
  2828. 1:41:09long. Then the final two things we've
  2829. 1:41:11spoken about Well, we spoke about
  2830. 1:41:12caffeine.
  2831. 1:41:14We haven't spoken about alcohol, but let
  2832. 1:41:16me just say as the kind of headline of
  2833. 1:41:18it, alcohol is not a sleep aid. Many
  2834. 1:41:20people use it as a sleep aid. It is not
  2835. 1:41:23your friend. Alcohol again is a
  2836. 1:41:25sedative, so it knocks you out. The
  2837. 1:41:27second is that it fragments your sleep.
  2838. 1:41:29So, you wake up, your sleep is littered
  2839. 1:41:31with all of these small awakenings. Most
  2840. 1:41:34of them you don't remember cuz it's too
  2841. 1:41:35brief, but it makes for miserable lousy
  2842. 1:41:38quality sleep. And the final thing is
  2843. 1:41:40that it alcohol is very good at blocking
  2844. 1:41:42your REM sleep or your dream sleep,
  2845. 1:41:43which we know is critical for many other
  2846. 1:41:45functions as well. So, alcohol's not
  2847. 1:41:47your friend. That's the sort of the
  2848. 1:41:48final tip. Again, you know, just every
  2849. 1:41:51if you're with friends, have a glass of
  2850. 1:41:54red wine. Just know, okay, my sleep's
  2851. 1:41:56not going to be great that night.
  2852. 1:41:58Yeah, okay.
  2853. 1:41:59I mean, that's you know, I'm not yeah,
  2854. 1:42:01I'm
  2855. 1:42:03whatever it's just, you know, live life
  2856. 1:42:05Of course, yeah.
  2857. 1:42:05I'm not saying that.
  2858. 1:42:06I I was I was thinking there about the
  2859. 1:42:08other sort of behavioral things that we
  2860. 1:42:10do that harm our sleep as well. We
  2861. 1:42:12talked about coffee earlier on, avoiding
  2862. 1:42:13that. It's weird that people drink it
  2863. 1:42:15after dessert in the evenings. I've
  2864. 1:42:17never understood that. Guess that's an
  2865. 1:42:18old tradition. Um but the other thing
  2866. 1:42:20obviously that the modern generation are
  2867. 1:42:22even more susceptible to is to
  2868. 1:42:24have a quick TikTok. Look at the social
  2869. 1:42:26media account or something. Now, I
  2870. 1:42:29thought, you know, there's a lot of
  2871. 1:42:30different products out there that are
  2872. 1:42:32trying to help with the the the light
  2873. 1:42:34that comes from these screens that I
  2874. 1:42:35think is the cause of what's keeping us
  2875. 1:42:37awake. But there's this little button
  2876. 1:42:39called dark mode on my iPad. Oh, there's
  2877. 1:42:41also one called night shift. So, if I
  2878. 1:42:43just pop that on,
  2879. 1:42:46Bob's your uncle.
  2880. 1:42:47And this and I can crack on with my
  2881. 1:42:49screen time.
  2882. 1:42:50True or false?
  2883. 1:42:53Partly true.
  2884. 1:42:54Oh, good. Okay, partly. So, I can just
  2885. 1:42:56pop that on night mode and dark mode and
  2886. 1:42:58then I can carry on using my iPad.
  2887. 1:43:00Partly true.
  2888. 1:43:02So, it turns out that the blue light
  2889. 1:43:04from screens does have an impact on
  2890. 1:43:07sleep. There's a great study done by
  2891. 1:43:08Harvard Medical School by some
  2892. 1:43:10colleagues there. And they showed that
  2893. 1:43:12reading for an hour on an iPad just
  2894. 1:43:15before bed relative to just reading a
  2895. 1:43:17book in dim light, firstly, it delayed
  2896. 1:43:20the time with which people fell asleep.
  2897. 1:43:22So, it took them a lot longer to fall
  2898. 1:43:24asleep. Second, it reduced the total
  2899. 1:43:26amount of sleep that they had. Third, it
  2900. 1:43:29decreased a sleep-related hormone called
  2901. 1:43:31melatonin. It delayed the release of
  2902. 1:43:33that melatonin and it reduced the amount
  2903. 1:43:35of melatonin. And finally, it reduced
  2904. 1:43:37the amount of rapid eye movement sleep.
  2905. 1:43:40So, it had
  2906. 1:43:40Significantly.
  2907. 1:43:41Significantly.
  2908. 1:43:42point, how how significantly?
  2909. 1:43:43So, it delayed the release by about
  2910. 1:43:45somewhere between 90 minutes to 2 hours
  2911. 1:43:48across the individuals. So, in other
  2912. 1:43:49words, your brain wasn't So, what
  2913. 1:43:51melatonin does, it's a it's called the
  2914. 1:43:54hormone of darkness or the vampire
  2915. 1:43:55hormone just because not
  2916. 1:43:58cuz it makes you want to bite into
  2917. 1:43:59people's necks, but because it signals
  2918. 1:44:02to your brain that it's night time, that
  2919. 1:44:04it's darkness.
  2920. 1:44:05And so, your brain needs the signal of
  2921. 1:44:07melatonin for it to understand when is
  2922. 1:44:10it dark. In other words, it needs to
  2923. 1:44:11understand by way of melatonin when it
  2924. 1:44:14is time to fall asleep.
  2925. 1:44:16And when you're bathed in electric light
  2926. 1:44:18at night, and especially when you're
  2927. 1:44:19getting blue light from these devices,
  2928. 1:44:21your brain is fooled into thinking it's
  2929. 1:44:23still daytime. And when there is light
  2930. 1:44:26emitting through your retina, coming
  2931. 1:44:28into your brain, it signals to a part of
  2932. 1:44:30your brain to hit the brakes on
  2933. 1:44:33melatonin, and your brain will not
  2934. 1:44:35release melatonin. So, what was
  2935. 1:44:36happening with this iPad reading is that
  2936. 1:44:38you were artificially telling the brain
  2937. 1:44:40it's still daytime, and the brakes on
  2938. 1:44:43melatonin was still shut on. And so,
  2939. 1:44:45melatonin was not starting to be
  2940. 1:44:47released until much later.
  2941. 1:44:50And what was it also interesting about
  2942. 1:44:51this study, by the way, is that when
  2943. 1:44:52they stopped the iPad reading, the sleep
  2944. 1:44:54disrupted pattern continued for several
  2945. 1:44:57days later. In other words, it was
  2946. 1:44:58almost like a drug that it had a wash
  2947. 1:45:00out period, that it was a blast radius
  2948. 1:45:02to it.
  2949. 1:45:03Now, there's been some great work by a
  2950. 1:45:06wonderful sleep scientist in Australia,
  2951. 1:45:08Michael Gradisar, and he has added to
  2952. 1:45:11this story, and he said it's not just
  2953. 1:45:14the blue light. These devices, the
  2954. 1:45:16principal function of these devices is
  2955. 1:45:19that they are attention capture devices.
  2956. 1:45:21Just like you said, "I'm just going to
  2957. 1:45:22have a wee little Tik Tok before bed."
  2958. 1:45:25They are in the attention economy.
  2959. 1:45:29And all they care about is capturing
  2960. 1:45:31your attention for a current currency,
  2961. 1:45:33and they make a lot of money from it.
  2962. 1:45:35What that attention does is that it
  2963. 1:45:37stimulates your brain. And when your
  2964. 1:45:39brain is stimulated, it's very difficult
  2965. 1:45:41for you to fall asleep, and it creates
  2966. 1:45:43what we call sleep procrastination.
  2967. 1:45:45Where you're lying in bed, and you could
  2968. 1:45:47be perfectly sleepy, and you could fall
  2969. 1:45:49asleep right now.
  2970. 1:45:51But then you sort of check social media,
  2971. 1:45:53and you think, "Oh, I'll just shoot that
  2972. 1:45:54last email." And then I'll order that
  2973. 1:45:56last thing on sort of, you know, Amazon.
  2974. 1:45:59Uh and then you get a text back from
  2975. 1:46:00your friend, and you start texting them.
  2976. 1:46:02And and then you look up, and it's now
  2977. 1:46:04an hour later, and you're an hour
  2978. 1:46:06deficient on sleep. So, it's the
  2979. 1:46:08activation of your cerebral cortex by
  2980. 1:46:11these devices that is perhaps the more
  2981. 1:46:13harmful aspect of them regarding your
  2982. 1:46:16sleep.
  2983. 1:46:17Now,
  2984. 1:46:18here again, I don't want to be
  2985. 1:46:20finger-wagging. You know, the genie of
  2986. 1:46:22technology is out the bottle, and it's
  2987. 1:46:24not going back in anytime soon. There's
  2988. 1:46:26nothing that I'm going to say as a sleep
  2989. 1:46:28researcher that's going to change that.
  2990. 1:46:30I don't take my phone into my bedroom.
  2991. 1:46:33I put my phone uh out in the kitchen. I
  2992. 1:46:36don't uh see it until morning. But lots
  2993. 1:46:38of people do, and fair enough. But
  2994. 1:46:41there's another rule uh that I've stolen
  2995. 1:46:43from another friend uh called Michael
  2996. 1:46:45Grandner, who's uh here in America at
  2997. 1:46:47the university
  2998. 1:46:48um of uh Tucson in Arizona. He has this
  2999. 1:46:51great rule regarding technology, and
  3000. 1:46:53it's the following, that if you really
  3001. 1:46:55must take your phone into your bedroom,
  3002. 1:46:57you can only use it
  3003. 1:47:00standing up.
  3004. 1:47:02And what you'll find is that after about
  3005. 1:47:046 or 7 minutes standing up, you think,
  3006. 1:47:07"Ah, I'm just going to I'm just going to
  3007. 1:47:08sit down on the bed." And at that point,
  3008. 1:47:10as soon as your backside hits the bed,
  3009. 1:47:11you're done. You've got to put the phone
  3010. 1:47:13away. I think it's a great rule of thumb
  3011. 1:47:14if uh if you need to take technology in
  3012. 1:47:16the bedroom. Um
  3013. 1:47:17I'm going to apply that. The other thing
  3014. 1:47:19I wanted to ask was about sleep and
  3015. 1:47:21weight loss.
  3016. 1:47:23Had a lot of health experts on this
  3017. 1:47:24podcast recently, but none of them have
  3018. 1:47:26really talked to me about the role that
  3019. 1:47:28sleep or sleep deprivation plays in
  3020. 1:47:32weight.
  3021. 1:47:33Is there a relationship?
  3022. 1:47:35It's probably one of the most
  3023. 1:47:37well-defined relationships that we know
  3024. 1:47:40in all of sleep science.
  3025. 1:47:42And it is at least a three-part story.
  3026. 1:47:46So, the first emerging evidence came in
  3027. 1:47:49terms of um hormones.
  3028. 1:47:51So, there are what we call
  3029. 1:47:53appetite-regulating hormones, and the
  3030. 1:47:55two principal ones of concern here are
  3031. 1:47:57something called leptin and ghrelin.
  3032. 1:48:00Now, leptin, when it's released, will
  3033. 1:48:03signal to your brain that you're
  3034. 1:48:05satisfied with your food, you are
  3035. 1:48:07satiated, and you are no longer hungry.
  3036. 1:48:11Ghrelin does the opposite. When ghrelin
  3037. 1:48:14is released, it says, "No, you're not
  3038. 1:48:16satisfied with your food. You are not
  3039. 1:48:19full. You still want to eat more. You
  3040. 1:48:21are still hungry."
  3041. 1:48:23And some of the first studies they
  3042. 1:48:24started to do uh just limit people,
  3043. 1:48:27restrict people's sleep to 6 hours or 5
  3044. 1:48:29hours or 4 hours, and what they found
  3045. 1:48:32was that um there was
  3046. 1:48:34firstly, that signal leptin that says,
  3047. 1:48:37"No, you're satisfied with your food.
  3048. 1:48:39You don't want to eat any more. You're
  3049. 1:48:40full."
  3050. 1:48:42That signal of fullness, satiation, was
  3051. 1:48:45decreased by 18%.
  3052. 1:48:48If that wasn't bad enough, ghrelin,
  3053. 1:48:50which is the hunger hormone, that leaped
  3054. 1:48:53up by 28%.
  3055. 1:48:58Overall hunger levels rose by about uh
  3056. 1:49:0126%.
  3057. 1:49:03So, firstly, you are It's almost like
  3058. 1:49:06double jeopardy that you are getting
  3059. 1:49:08punished twice for the same crime of not
  3060. 1:49:11sleeping enough. Once by losing the
  3061. 1:49:13signal of, "I'm full.
  3062. 1:49:16I I don't want to eat any more. And once
  3063. 1:49:18again, for the no, I'm much more hungry
  3064. 1:49:21and I'm just going to overeat, which is
  3065. 1:49:23ghrelin.
  3066. 1:49:25So, what that produces is a profile of
  3067. 1:49:29increased eating. So, on average,
  3068. 1:49:31underslept individuals started to eat in
  3069. 1:49:33those studies about 3 to 400
  3070. 1:49:37extra calories at each sit at each
  3071. 1:49:40sitting by way of insufficient sleep.
  3072. 1:49:44Then, what they discovered is that it's
  3073. 1:49:46not just
  3074. 1:49:47that you want to eat more, it's what it
  3075. 1:49:49is that you have a craving for when you
  3076. 1:49:51are underslept.
  3077. 1:49:53And this is the problem. What they found
  3078. 1:49:55is that when you are underslept, you eat
  3079. 1:49:57more of everything, but you especially
  3080. 1:49:59eat more of these heavy-hitting starchy
  3081. 1:50:02carbohydrates, bread, pasta, pizza.
  3082. 1:50:06The The next thing that you started to
  3083. 1:50:08eat have a preference for was simple
  3084. 1:50:10sugary foods, sweets and chocolate. And
  3085. 1:50:13then finally, you started to crave very
  3086. 1:50:15salty food. And high sodium food intake
  3087. 1:50:19will increase your blood pressure.
  3088. 1:50:22So, that was the first of the the three
  3089. 1:50:24mechanisms. Then, we did a study where
  3090. 1:50:27we said, perhaps it's not just the
  3091. 1:50:28circulating hormones in the body, the
  3092. 1:50:30brain is the ultimate arbiter of your
  3093. 1:50:34food decisions. So, what's going on in
  3094. 1:50:36the brain? So, we took a group of
  3095. 1:50:37perfectly healthy individuals and we put
  3096. 1:50:39them through the experiment twice, once
  3097. 1:50:41when they'd had a full 8 hours of sleep
  3098. 1:50:43and once when we deprived them of
  3099. 1:50:45And then the next day, we placed them
  3100. 1:50:46inside an MRI scanner and we showed them
  3101. 1:50:49images of lots of different foods that
  3102. 1:50:51range from being sort of, you know, very
  3103. 1:50:53healthy to being very unhealthy and sort
  3104. 1:50:56of ice cream and, you know, chocolate
  3105. 1:50:59and pizza and things to leafy salads and
  3106. 1:51:02nuts and greens and vegetables.
  3107. 1:51:05And we asked them to rate how much they
  3108. 1:51:07wanted that food for each item. Now, we
  3109. 1:51:10we something a bit sort of dastardly to
  3110. 1:51:12make it more ecologically correct so
  3111. 1:51:15that they weren't just saying, "Okay,
  3112. 1:51:16they probably think I should probably
  3113. 1:51:17say that's healthy." We said, "We're
  3114. 1:51:19going to randomly select one of these
  3115. 1:51:21images, these food images that you see,
  3116. 1:51:23and after you get out the brain scanner,
  3117. 1:51:25we're going to give you that food, and
  3118. 1:51:26we're going to politely ask you to eat
  3119. 1:51:27it all."
  3120. 1:51:28So, it made it a bit more realistic so
  3121. 1:51:30that choices were more, you know, as
  3122. 1:51:32much as that we could.
  3123. 1:51:33So, what we found is that when they were
  3124. 1:51:35sleep deprived, the deep hedonic centers
  3125. 1:51:39of the emotional centers of the brain,
  3126. 1:51:42these desire centers, these reward
  3127. 1:51:44centers,
  3128. 1:51:45uh they ramped up in their activity in
  3129. 1:51:47response to these highly desirable,
  3130. 1:51:49highly unhealthy foods.
  3131. 1:51:52So, these more basic sort of, you know,
  3132. 1:51:54guttural parts of the brain, as it were,
  3133. 1:51:57um these reward centers were lighting up
  3134. 1:52:00much more strongly when you're sleep
  3135. 1:52:01deprived. Worse still, the impulse
  3136. 1:52:04control regions in the front of the
  3137. 1:52:06brain, what we call the prefrontal
  3138. 1:52:07cortex, they were shut down. They were
  3139. 1:52:09taken offline.
  3140. 1:52:11So, as a consequence, you lost your
  3141. 1:52:12impulse control, and that's why you
  3142. 1:52:15start to then say, you know, when I'm
  3143. 1:52:16sleep deprived at the food sort of
  3144. 1:52:19buffet,
  3145. 1:52:20I'm not I'm not going to do salad. I'm
  3146. 1:52:22just going to
  3147. 1:52:23that pizza looks awful good, or that
  3148. 1:52:25pasta with the cream I'm just going to
  3149. 1:52:27go into that all go. So,
  3150. 1:52:30so you're it's what we call a pattern in
  3151. 1:52:32terms of brain activity uh in
  3152. 1:52:34neuroscience of hedonic eating that your
  3153. 1:52:37brain goes into this hedonic desire
  3154. 1:52:39profile. So, now we understood it's not
  3155. 1:52:42just hormones in the body, it's also
  3156. 1:52:44changes in the brain.
  3157. 1:52:45Then came the finding that there's
  3158. 1:52:47another chemical in the body that's
  3159. 1:52:49responsible.
  3160. 1:52:51And this comes on to cannabis.
  3161. 1:52:55When people um
  3162. 1:52:58uh when people when people that you may
  3163. 1:53:00know have smoked uh cannabis, they'll
  3164. 1:53:02often say, "I get
  3165. 1:53:04viciously hungry. I get the munchies. I
  3166. 1:53:06get really hungry. That's no coincidence
  3167. 1:53:08because cannabis will stimulate
  3168. 1:53:11appetite. Now, we all have naturally
  3169. 1:53:14occurring cannabis compounds in our
  3170. 1:53:17brain and our bodies. They are called
  3171. 1:53:20endocannabinoids.
  3172. 1:53:22Endo meaning comes from inside us.
  3173. 1:53:24Um whereas the cannabis that comes
  3174. 1:53:27externally when you sort of smoke it or
  3175. 1:53:29um take edibles.
  3176. 1:53:31So,
  3177. 1:53:33endocannabinoids do many things for the
  3178. 1:53:35brain and the body, but one of the
  3179. 1:53:36things that they do is control your
  3180. 1:53:38appetite and your hunger. And what we
  3181. 1:53:40found is that when you sleep deprived
  3182. 1:53:42individuals, these naturally occurring
  3183. 1:53:44endocannabinoids rocketed up by over
  3184. 1:53:4720%.
  3185. 1:53:49Cranking up people's appetite.
  3186. 1:53:51Mhm.
  3187. 1:53:52And so,
  3188. 1:53:54these three ways lead you to start
  3189. 1:53:56packing on, you know, when insufficient
  3190. 1:53:59sleep is occurring, when sleep gets
  3191. 1:54:00short, your waistline typically starts
  3192. 1:54:03to expand.
  3193. 1:54:04And we now understand the reasons. If
  3194. 1:54:06that wasn't bad enough,
  3195. 1:54:09It is bad enough.
  3196. 1:54:09The final Yeah, I know. Yeah. Can you
  3197. 1:54:11just stop, Matthew? Honestly, I really
  3198. 1:54:13uh the the last thing that we discovered
  3199. 1:54:15is that
  3200. 1:54:17let's say that you're trying to be
  3201. 1:54:18really careful and you're trying to diet
  3202. 1:54:20and you're trying to lose weight.
  3203. 1:54:22If you're not getting sufficient sleep,
  3204. 1:54:25then 60% of all of the weight that you
  3205. 1:54:28lose will come from lean muscle mass.
  3206. 1:54:32Oh god, no.
  3207. 1:54:33And not fat.
  3208. 1:54:34Not the muscle.
  3209. 1:54:35I know exactly. So, in other words, when
  3210. 1:54:37you are dieting but you are under-slept,
  3211. 1:54:40you lose what you want to keep, which is
  3212. 1:54:42muscle,
  3213. 1:54:44and you keep what you want to lose,
  3214. 1:54:46which is fat.
  3215. 1:54:48So, again, it's
  3216. 1:54:50I'm sold.
  3217. 1:54:51not an ideal situation.
  3218. 1:54:53My last question for you, in fact, was
  3219. 1:54:55of all the subject matter we've talked
  3220. 1:54:57about,
  3221. 1:54:58what is the most interesting thing we've
  3222. 1:54:59missed in your view? The thing that you
  3223. 1:55:02think is most pertinent or interesting
  3224. 1:55:03or significant or that perks people up
  3225. 1:55:06or sits them on the end of their chair
  3226. 1:55:07when you discuss it?
  3227. 1:55:11I think the only other area that
  3228. 1:55:14fascinates people even more than sleep
  3229. 1:55:18is dreaming.
  3230. 1:55:19Mhm.
  3231. 1:55:21So, dreaming above and beyond the stage
  3232. 1:55:24of which it comes from, which is
  3233. 1:55:25principally called rapid eye movement
  3234. 1:55:27sleep or dream sleep,
  3235. 1:55:28REM sleep provides a set of
  3236. 1:55:30physiological and
  3237. 1:55:32benefits, but dreaming we've now
  3238. 1:55:34discovered, even above and beyond that,
  3239. 1:55:37provides benefits. And it provides at
  3240. 1:55:39least two benefits. The first is
  3241. 1:55:41creativity. I was telling you that
  3242. 1:55:42during deep sleep you cement individual
  3243. 1:55:44memories. You grab memories and you
  3244. 1:55:47shift them from a short-term storage
  3245. 1:55:48reservoir to a long-term storage
  3246. 1:55:50reservoir and you strengthen the circuit
  3247. 1:55:52of those memories. So, you future-proof
  3248. 1:55:54information. But, that's individual
  3249. 1:55:56memories. What we discovered is that
  3250. 1:55:58sleep is much more intelligent than you
  3251. 1:56:00ever thought possible. That it's during
  3252. 1:56:03REM sleep, and particularly during
  3253. 1:56:04dreaming, that we take all of the
  3254. 1:56:06individual pieces of information that
  3255. 1:56:08we've been learning and we start
  3256. 1:56:10interconnecting them and associating
  3257. 1:56:12them with all of our back catalog of
  3258. 1:56:15stored information.
  3259. 1:56:17And so, what dream sleep, one of the
  3260. 1:56:18functions of dream sleep, is to
  3261. 1:56:21cross-link
  3262. 1:56:22and associate new memories together. So,
  3263. 1:56:24you wake up the next day having after
  3264. 1:56:27dream sleep with a revised mind web of
  3265. 1:56:31associations and those are capable of
  3266. 1:56:33divining solutions to previously
  3267. 1:56:35impenetrable problems.
  3268. 1:56:37So, think of dreaming as
  3269. 1:56:40it's almost like informational alchemy.
  3270. 1:56:43That you start to fuse things together
  3271. 1:56:45that shouldn't normally go together.
  3272. 1:56:47But, when they do, they cause marked
  3273. 1:56:49advances in your thinking, in your
  3274. 1:56:51productivity, in your ingenuity.
  3275. 1:56:53And in that way, you go to sleep with
  3276. 1:56:56the pieces of the jigsaw,
  3277. 1:56:58but you wake up with the puzzle
  3278. 1:57:00complete. And I would argue that that's
  3279. 1:57:02the difference between knowledge, which
  3280. 1:57:04is remembering the individual pieces,
  3281. 1:57:07and wisdom,
  3282. 1:57:08which is knowing what it all means when
  3283. 1:57:11you fit them together. That's one of the
  3284. 1:57:13functions of dreaming. It's the reason,
  3285. 1:57:15by the way, that you've never been told
  3286. 1:57:16to stay awake on a problem.
  3287. 1:57:18Yeah.
  3288. 1:57:19Um
  3289. 1:57:20The other function of dreaming that we
  3290. 1:57:23know of is that dreaming provides a form
  3291. 1:57:25of emotional first aid.
  3292. 1:57:28That we've We've done a lot of work and
  3293. 1:57:30we came up with a a theory that was
  3294. 1:57:31called dreaming as overnight therapy.
  3295. 1:57:35And what we've discovered is that when
  3296. 1:57:37we go into dream sleep, particularly
  3297. 1:57:39based on its neurochemical profile and
  3298. 1:57:40its physiological anatomy of the brain,
  3299. 1:57:43um the dreaming brain will take
  3300. 1:57:46difficult, painful experiences,
  3301. 1:57:47sometimes traumatic experiences,
  3302. 1:57:50and it will essentially strip away the
  3303. 1:57:52bitter emotional rind from the
  3304. 1:57:55informational orange. So, let's take a
  3305. 1:57:57step back. What makes a memory
  3306. 1:57:58emotional? What makes a memory emotional
  3307. 1:58:00is that at the time of the experience,
  3308. 1:58:03that experience triggered a strong
  3309. 1:58:05visceral reaction. And that visceral
  3310. 1:58:07reaction is useful to the brain, and it
  3311. 1:58:09wraps that experience in this blanket of
  3312. 1:58:12what we call emotion. It red flags it
  3313. 1:58:14and prioritizes it in the brain. So, now
  3314. 1:58:16you've created a memory of an emotional
  3315. 1:58:18event. In other words, you've created an
  3316. 1:58:20emotional memory.
  3317. 1:58:22But what dream sleep does is then it
  3318. 1:58:25takes that useful emotional memory and
  3319. 1:58:28it will detox the emotion from the
  3320. 1:58:30memory. It strips the bitter emotional
  3321. 1:58:33rind from the informational orange.
  3322. 1:58:35Mhm.
  3323. 1:58:36It's almost And that's why we called it
  3324. 1:58:39overnight therapy. So, that the next day
  3325. 1:58:41you come back, and now you feel better
  3326. 1:58:43about those experiences.
  3327. 1:58:45So, you have a memory of an emotional
  3328. 1:58:49event, but it's no longer emotional
  3329. 1:58:51itself. You don't regurgitate that same
  3330. 1:58:53visceral reaction that you had at the
  3331. 1:58:55time of learning. So, the brain has done
  3332. 1:58:58this elegant trick of stripping the
  3333. 1:59:00emotion from the memory.
  3334. 1:59:02So, it's That's the That's the the
  3335. 1:59:05second benefit um is that it provides
  3336. 1:59:08It's not time that heals all wounds. It
  3337. 1:59:11is time during sleep and particularly
  3338. 1:59:13during dream sleep that provides
  3339. 1:59:15emotional convalescence.
  3340. 1:59:17It's funny because there's a the
  3341. 1:59:18stereotype that we should never go to
  3342. 1:59:19bed angry at each other.
  3343. 1:59:21You will wake up far less angry as a
  3344. 1:59:24consequence.
  3345. 1:59:26Matt, we have a closing tradition on
  3346. 1:59:27this podcast where the last guest asks a
  3347. 1:59:29question for the next guest not knowing
  3348. 1:59:30who they're going to ask it for.
  3349. 1:59:32Um the question that's been left for you
  3350. 1:59:33from our previous guest, obviously they
  3351. 1:59:35didn't know who they're leaving it for,
  3352. 1:59:36but uh it's a very I love these
  3353. 1:59:37questions when they're challenging.
  3354. 1:59:38Um
  3355. 1:59:40what is the biggest way in which you are
  3356. 1:59:41a contradiction?
  3357. 1:59:46Gosh, I'm a contradiction
  3358. 1:59:48in so many ways. I think
  3359. 1:59:52I'm a contradiction in the sense that
  3360. 1:59:54within my profession and with this field
  3361. 1:59:57of sleep, I feel very comfortable. I'm
  3362. 2:00:00reticent to say confident, but I am very
  3363. 2:00:03comfortable to get on stage, you know,
  3364. 2:00:05give a TED Talk in front of couple of
  3365. 2:00:07thousand people and my heart rate will
  3366. 2:00:09be very stable. I probably
  3367. 2:00:14I probably don't feel I I feel more
  3368. 2:00:17myself on stage alone in front of
  3369. 2:00:20thousands of people than I do at any
  3370. 2:00:22other time in my life. That's where I
  3371. 2:00:24feel most myself.
  3372. 2:00:26But yet I'm a contradiction because off
  3373. 2:00:30stage
  3374. 2:00:31I'm very insecure.
  3375. 2:00:34I'm very much an introvert. I'm very
  3376. 2:00:37shy.
  3377. 2:00:38Um I don't like being the focus of
  3378. 2:00:41attention.
  3379. 2:00:42And so, those two things I've often
  3380. 2:00:44wrestled with, but the more people I've
  3381. 2:00:46spoken to sort of now being out in the
  3382. 2:00:48public sphere and sort of
  3383. 2:00:50sort of being more in the sort of public
  3384. 2:00:51intellectual realm, you start to meet,
  3385. 2:00:53you know, very famous people, and you
  3386. 2:00:57meet, you know, musicians, and
  3387. 2:01:00and what you learn is that they're very
  3388. 2:01:01similar, that they say that they become
  3389. 2:01:03this version of themselves on stage, and
  3390. 2:01:06then when they're off stage, they are a
  3391. 2:01:08radically different person. But I am
  3392. 2:01:10such a contradiction in that sense. I
  3393. 2:01:12feel very comfortable and very secure on
  3394. 2:01:16stage in front of thousands people. And
  3395. 2:01:19for many people, public speaking is one
  3396. 2:01:21of the most anxiogenic things you can
  3397. 2:01:24ask anyone to do. But for me,
  3398. 2:01:26heart rate is probably in the, you know,
  3399. 2:01:29mid-40s.
  3400. 2:01:31Uh, very relaxing for me. But then, put
  3401. 2:01:34me in a room, you know, a small room of
  3402. 2:01:36a couple of people, my heart rate's
  3403. 2:01:37probably through the roof, and I've
  3404. 2:01:38become very introverted. So, I'm a
  3405. 2:01:39contradiction in that sense.
  3406. 2:01:41Um,
  3407. 2:01:43yeah.
  3408. 2:01:45Matthew, thank you. Thank you for for
  3409. 2:01:47making the time today. I've I've I've
  3410. 2:01:49wanted to speak to you for many, many
  3411. 2:01:50years, and you absolutely never
  3412. 2:01:52disappoint anybody. So, you're
  3413. 2:01:54That's very kind of you to say.
  3414. 2:01:55It's exceptionally important work, and
  3415. 2:01:56as you said at the start of this
  3416. 2:01:57conversation, we often neglect the
  3417. 2:02:00medicinal properties of a great night's
  3418. 2:02:02sleep over things like diet and medicine
  3419. 2:02:04or exercise, whatever whatever else it
  3420. 2:02:06is. But your your voice and the the the
  3421. 2:02:08passion that sits behind it has led a a
  3422. 2:02:11charge in society, which is waking us
  3423. 2:02:13up, no pun intended,
  3424. 2:02:15to the um the virtues and the power and
  3425. 2:02:18the importance of having a great night's
  3426. 2:02:20sleep. But in a nice way, in a way that
  3427. 2:02:22I find it really empowering and
  3428. 2:02:23actionable, and that's the most
  3429. 2:02:24important thing. So, thank you for that,
  3430. 2:02:25Matthew.
  3431. 2:02:26Thank you, and thank you for saying that
  3432. 2:02:27last part especially. I I don't think I
  3433. 2:02:30can um
  3434. 2:02:31lay claim to that sort of uh early on. I
  3435. 2:02:33think I'm doing much better as uh much
  3436. 2:02:35better. I'm doing a little bit better as
  3437. 2:02:37a public communicator, and being less
  3438. 2:02:39puritanical and dictatorial in my sleep
  3439. 2:02:41message. I think I did a terrible job
  3440. 2:02:43coming out. I'm learning and I'm being
  3441. 2:02:45more sensitive, but I'm always lovely to
  3442. 2:02:48hear feedback from folks about what I'm
  3443. 2:02:49not doing well cuz I would love to do
  3444. 2:02:51this better and better if I can. Um but
  3445. 2:02:54thank you for saying those kind words
  3446. 2:02:55and thank you again for having me on,
  3447. 2:02:57giving me this opportunity to speak. I
  3448. 2:02:59now will anoint you as a sleep
  3449. 2:03:01ambassador from this point forward, so
  3450. 2:03:04thank you so much again, Stephen. I
  3451. 2:03:06really appreciate you.
  3452. 2:03:10Quick word from one of our sponsors. I
  3453. 2:03:11have to say I've been on a bit of a
  3454. 2:03:13journey with this brand because when I
  3455. 2:03:15started my business in new territories,
  3456. 2:03:17when we first moved Social Chain to the
  3457. 2:03:19to New York City, the first place we
  3458. 2:03:21went to was WeWork. We moved four of our
  3459. 2:03:22team members out to New York City and we
  3460. 2:03:25built the business from there. Um I have
  3461. 2:03:27to say there's something magical about
  3462. 2:03:28WeWorks. I've spent the last two or
  3463. 2:03:31three weeks in LA in a WeWork and as you
  3464. 2:03:33walk in the front door every day, it's
  3465. 2:03:35almost like that sense of community,
  3466. 2:03:37that sense of magic, excitement,
  3467. 2:03:39camaraderie is tangible. And you don't
  3468. 2:03:42get that when you're working at home.
  3469. 2:03:43You don't get that often when you're sat
  3470. 2:03:45in your bed on your laptop. There's
  3471. 2:03:47something about getting out and getting
  3472. 2:03:48into a WeWork that makes me feel a sense
  3473. 2:03:51of entrepreneurship and and creativity
  3474. 2:03:53and building. And the way that WeWorks
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  3476. 2:03:57they offer subscriptions so that you can
  3477. 2:03:59work, you know, on demand, but also that
  3478. 2:04:02the flexibility of the contracts means
  3479. 2:04:03that it's just the perfect place for
  3480. 2:04:05businesses to scale their companies. And
  3481. 2:04:07if you haven't checked out WeWork and
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  3487. 2:04:23You know, I never really usually pick
  3488. 2:04:24the chocolate flavored Huel. My favorite
  3489. 2:04:26are the banana flavor. I love the salted
  3490. 2:04:29caramel flavor. But recently, I think I
  3491. 2:04:33in part blame Jack in my team, who's
  3492. 2:04:35obsessed with the chocolate flavor Huel.
  3493. 2:04:37I've started drinking the chocolate
  3494. 2:04:38flavor Huel for the first time and I
  3495. 2:04:39absolutely love them. My life means that
  3496. 2:04:42I sometimes disregard my diet and it's
  3497. 2:04:44funny, that's part of the reason why
  3498. 2:04:45I've had a lot of guests on this podcast
  3499. 2:04:47recently that talk about diet and health
  3500. 2:04:48and and those kinds of things because I
  3501. 2:04:50am trying to make an active effort to be
  3502. 2:04:52more healthy, to lose a little bit of
  3503. 2:04:53weight as well, but to be more healthy.
  3504. 2:04:55And the role that Huel plays in my life
  3505. 2:04:57is it means that in those moments where
  3506. 2:04:58sometimes I might reach for
  3507. 2:05:01you know,
  3508. 2:05:02junk foods,
  3509. 2:05:04having an option that is nutritionally
  3510. 2:05:05complete, that is high in fiber, that is
  3511. 2:05:07incredibly high in protein, that has all
  3512. 2:05:09the vitamins and minerals that my body
  3513. 2:05:10needs, within arms reach, that I can
  3514. 2:05:13consume on the go, is where Huel has
  3515. 2:05:15been a game changer for me.

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