The Truth About Peptide Injections: GLP-1s, BPC-157, GHK-Cu, & What They Do for Your Skin & Body — Transcript
Full transcript
- 0:00I think if you use a GLP-1 correctly,
- 0:03>> Mhm.
- 0:04>> it's my favorite tool in my toolbox.
- 0:06>> Yeah.
- 0:07>> Because we have so much safety data. I
- 0:09had a patient with chronic pelvic pain.
- 0:11She had given birth to two kids, and she
- 0:13was doing pelvic floor physical therapy,
- 0:15and she just had this chronic pelvic
- 0:16pain. She could not walk.
- 0:17>> Mhm.
- 0:18>> She was like, "Every time I walk, I'm in
- 0:19so much pain."
- 0:20We microdosed, and I'm talking like 0.25
- 0:23mg of a GLP-1.
- 0:25>> Mhm.
- 0:25>> And I was really I'm like she she was a
- 0:28you know, a
- 0:29normal girl.
- 0:30>> Yeah.
- 0:30>> Normal woman, normal body type, but I
- 0:32was like, "You're not going to lose
- 0:33[music] muscle.
- 0:34>> Yeah.
- 0:34>> You're going to eat the nutrition that
- 0:35you need to eat."
- 0:36>> Yep.
- 0:36>> We did the protein goals. She put on
- 0:39muscle,
- 0:40and her pain went away. Welcome to Glo
- 0:41Lab. We're going to have a lot of fun
- 0:43and learn a lot together.
- 0:46Peptide injections are really popular,
- 0:47especially on social media. But, I think
- 0:49it's really important to know that they
- 0:51are experimental. There aren't a lot of
- 0:53human studies, and [music] where you're
- 0:54getting it really matters. That's why my
- 0:57guest today is Mimi Deal. She is a
- 0:58board-certified nurse practitioner.
- 1:00[music] She's also the founder of Rebel
- 1:01Wellness here in Miami, where she really
- 1:03focuses on functional health, especially
- 1:05for women. I happen to be one of her
- 1:06patients, and I go to her because I have
- 1:09autoimmune diseases like my Hashimoto's,
- 1:11and I also work with her on my hormones.
- 1:13And one aspect that we work together on
- 1:15is peptide injections, and whether I
- 1:16actually need them or not. So, I really
- 1:18think this is an informational
- 1:19conversation for anyone that is
- 1:21considering peptide injections, because
- 1:23there's a lot to know about them. Mimi.
- 1:25>> Hi.
- 1:25>> Second time back.
- 1:27>> [laughter]
- 1:28>> You guys, this is one of my favorite
- 1:30people ever ever. I've been working with
- 1:33her for an entire year now, ever since
- 1:35you came onto the podcast, and we've
- 1:36been working on just like I mean,
- 1:37everything. We look at everything that's
- 1:39going on with my body.
- 1:40>> Everything.
- 1:41>> Yeah.
- 1:41>> Inside out. Like, it's so important to
- 1:43look at the whole picture. And you're
- 1:45very health knowledgeable. So, when I
- 1:47work with patients who know different
- 1:48things that are out there, like you send
- 1:50me things on Instagram, and I think you
- 1:51send me different peptides, and
- 1:53different
- 1:53>> waiting for me sometimes to send you
- 1:54something that you've already launched.
- 1:56Yeah.
- 1:56>> I'm like, "How many patients are going
- 1:57to send me this? I love it so much. But
- 1:59I love it because it opens the
- 2:00conversation. And patients nowadays,
- 2:02like I hate to say this, but it's true.
- 2:05The medical industry has changed.
- 2:07Whether you're going to a hospital or
- 2:10small offices, they're businesses. The
- 2:12big hospitals are businesses, the small
- 2:13offices are still businesses, and you as
- 2:15a patient need to be an educated
- 2:17consumer. In the same way you research
- 2:19your blush, your mascara, who's going to
- 2:21go color your hair, research who you're
- 2:23going to go see.
- 2:24>> Yeah. For sure, especially for today's
- 2:26topic because we are talking about
- 2:27specifically injectable peptides.
- 2:30>> Yes.
- 2:30>> Which is funny because last time we had
- 2:31you on the podcast, we talked more about
- 2:33like menopause and overall women's
- 2:35health, like functional health. But this
- 2:37topic I feel like over the last year has
- 2:39really exploded because I asked you
- 2:40about it and you're like, well, it's
- 2:42still experimental, like it's hard to
- 2:43get them sometimes, the you know, like
- 2:45there were all these like challenges.
- 2:47But now it suddenly it feels like you
- 2:48can get them anywhere.
- 2:50>> Well, that's the dangerous thing, to be
- 2:51honest. So, we touched on NAD last time.
- 2:54And that we could do a whole episode on,
- 2:56but in general peptides, what happened
- 2:59was that peptides are old medicine.
- 3:01Insulin is a peptide. Oxytocin, the
- 3:03hormone that you release when you have
- 3:05an orgasm, when you have a contraction,
- 3:08that's a peptide. Peptides are basically
- 3:10First, I want to start by saying like,
- 3:11what is a peptide, right? Yeah. So,
- 3:12peptides are amino acids. Amino acids,
- 3:16think of them as letters in the
- 3:17alphabet. Then, when amino acids come
- 3:20together, they form a peptide, which is
- 3:22a word. And then, when you have a lot of
- 3:24words together, you get a sentence or a
- 3:26protein. So, many many uh peptides
- 3:28become a protein. So, that's what a
- 3:29peptide is. A peptide is an amino acid,
- 3:32and it sends a message to your body.
- 3:34>> Right.
- 3:34>> Your body naturally makes peptides. We
- 3:37produce 300 peptides. Insulin is a
- 3:40life-saving peptide. GLP-1, semaglutide,
- 3:43Ozempic, Mounjaro, tirzepatide, all
- 3:45peptides. So, peptides have been around
- 3:47for a while. They've also been used in
- 3:50off-label ways. So, like bodybuilders
- 3:53kind of started using them first
- 3:55experimentally in themselves.
- 3:56>> I actually think of it's for me, it was
- 3:58bodybuilders who started talking to me
- 4:00about peptides. It was a lot of like
- 4:02when I was working out with my personal
- 4:04trainers and all that and I would say to
- 4:05them like, "Why aren't I growing muscles
- 4:07faster?" Or, you know, like, "Why do I
- 4:10Why do I feel so weak?" Or like, "How do
- 4:11I get like a more, you know, like
- 4:13voluminous body over the next 2 months
- 4:15and stuff?" And they would say, "Well,
- 4:17you know that this person that you're
- 4:18showing me on Instagram is likely on
- 4:20some kind of a peptide.
- 4:21>> Yeah.
- 4:22>> Right?
- 4:22>> So, they started. Like, I I think they
- 4:24started with the bodybuilding world,
- 4:25right? Kind of like the way that things
- 4:27were secret, black market, you know,
- 4:29like behind the scenes your trainer
- 4:30would give them to you, whatever, you
- 4:31know, like there was less regulation.
- 4:33Then there was like a popularity that
- 4:36came out. Yeah, peptides became more
- 4:37popular. With that popularity, grifters
- 4:39came into the world and they started
- 4:41saying like,
- 4:42"Yes, I can make money off of a person.
- 4:44I can tell them that this is the
- 4:46end-all, be-all, that, "Oh my gosh, with
- 4:47this peptide you are going to have the
- 4:48tightest ass you've ever had. I'm going
- 4:50to give you this mister morlin your butt
- 4:52will bounce like it's never bounced,
- 4:54right? Like it's going to be amazing.
- 4:55>> Yep.
- 4:56>> But what happens is
- 4:57people who look at peptides like that
- 4:59are selling you a lie.
- 5:00>> I do want to throw out there, I have
- 5:02been on different peptides. And the
- 5:03first time I ever got on injectable
- 5:05peptides was with one of my personal
- 5:07trainers in the past. And that was
- 5:09because I had complained about not
- 5:11growing muscle. But then when I met you
- 5:12and we started talking about like HRT
- 5:14and everything, it, you know, it turned
- 5:16out it could also be something like, I
- 5:18mean, women just don't naturally
- 5:20>> It's hard to grow muscle.
- 5:20>> muscle, right? And so and so we started
- 5:23talking about like hormone replacement
- 5:25therapy and everything too is another
- 5:26way to to really build your muscle. So,
- 5:29I do want to point out there are
- 5:30different ways to do that. But something
- 5:32I think that was really interesting in
- 5:34working with you, you've always been
- 5:35very, I guess, methodical about it and
- 5:37thoughtful about peptides. Like if I
- 5:39bring up a peptide to Mimi, you're kind
- 5:41of like, "No, well, let's talk about
- 5:43what could be the side effects of this?"
- 5:45Or, you know, like issues when we need
- 5:46to make sure we do your labs to make
- 5:48sure that you're okay to do this because
- 5:50you know, there there could be things
- 5:51that happen. So can we talk about that a
- 5:53little bit?
- 5:53>> Absolutely. So when it comes to peptides
- 5:55and I think this is how you're going to
- 5:56know if you're working with a
- 5:57responsible peptide provider. We look at
- 5:59them in terms of systems. Like whenever
- 6:02someone asks me about a peptide, I say
- 6:03what what are we going to do with it?
- 6:05Like what's the purpose? Are we working
- 6:06on metabolism? Are we working on, you
- 6:09know, weights, body composition, muscle
- 6:11building? Are we working on your immune
- 6:13health? What what are we working on?
- 6:15Right? So like let's pick like our goal.
- 6:18And then we have to do labs. I firmly
- 6:20believe we have to do labs because
- 6:22a lot of these peptides, we only have
- 6:25animal studies and we only have in vitro
- 6:28studies, meaning in a test tube, in a
- 6:30little petri dish, right?
- 6:31>> dish, right? Or it's not an actual
- 6:33human. It's just seeing what it does to
- 6:34cells that sit inside a petri dish,
- 6:36right? Which is like so powerful.
- 6:39>> But that doesn't always translate.
- 6:40Right. So then we say, okay, this is
- 6:42going to be an N of one, a study of one.
- 6:45Because I do believe medicine is
- 6:46personalized. There is no other human
- 6:49being on this planet like you. Right?
- 6:51Right? Like you are just you and there's
- 6:53no one like you. I feel like Dr. Seuss
- 6:54every time I say it, right? So
- 6:56I'm going to look at your labs. I'm
- 6:58going to say, what is your personal
- 7:00history?
- 7:01>> Yeah.
- 7:01>> Do you have a history of cancer? Because
- 7:03then unfortunately, you're probably not
- 7:05going to be a candidate for a lot of
- 7:06peptides that would stimulate growth.
- 7:09Like some popular ones you hear on
- 7:11social media are BPC 157, okay? That's
- 7:14body protective compound 157. And that
- 7:17one, we really have minimal human
- 7:19studies on.
- 7:20>> Mhm.
- 7:21>> It's one of the most popular ones. I
- 7:22think it's because it's really benign in
- 7:25what it could do if it was bad. What we
- 7:27do see of the good is good.
- 7:28>> What's the good?
- 7:29>> It's anecdotal. So it's
- 7:30anti-inflammatory potentially.
- 7:31>> Okay.
- 7:32>> It's made in our gut.
- 7:33>> Oh.
- 7:33>> BPC is a peptide that we produce
- 7:35naturally in our gut.
- 7:36>> Okay.
- 7:36>> And now there's actually a a clinical
- 7:39trial going on in China
- 7:41>> Okay.
- 7:41>> for some muscle injury, I can't remember
- 7:44the exact specifics. There's also
- 7:46another small, not a perfect trial that
- 7:48was done here in the US by a physician
- 7:50here in the US, a small study where he
- 7:52injected BPC into patients' knees who
- 7:55were complaining of knee pain, and they
- 7:57reported improvement of pain.
- 7:58>> Okay.
- 7:58>> Then we have animal studies.
- 8:00>> Right.
- 8:01>> I personally have used BPC on myself.
- 8:02>> Okay. How have you used it?
- 8:04>> Yes.
- 8:04>> Okay.
- 8:05>> [laughter]
- 8:06>> I can't even remember at this point.
- 8:07>> You have. So, I personally think about
- 8:09how I use it very intentionally, very
- 8:11carefully. So, I'm going to go on to
- 8:13Glow Stack, and then we'll talk about
- 8:14how I used it.
- 8:15>> Right. That's when I used it.
- 8:16>> You did Glow Stack post-op.
- 8:18>> Mhm.
- 8:18>> So, I use Glow Glow Stack post-op
- 8:20because the mechanism behind why we're
- 8:23using it is what matters here. And we
- 8:25know in a conversation that we had very
- 8:28openly that, look, this is not going to
- 8:30replace you eating
- 8:32really well post-op.
- 8:33>> Mhm.
- 8:34>> It's not going to replace you sleeping
- 8:35post-op, op, recovering. You know, you
- 8:37can't just go run right after. No, you
- 8:39have to rest, recover. You have to do
- 8:40like the hyperbaric, the red light, all
- 8:42the things, but this is a tool. And so,
- 8:44the combination of something called BPC
- 8:46157, TB4, or sometimes the synthetic is
- 8:49TB5, thymosin beta 4, that's also
- 8:52another healing peptide. It helps with
- 8:54kind of the way that wounds close.
- 8:57>> Mhm.
- 8:57>> And then GHK-Cu, which I know you're
- 8:59familiar with GHK-Cu.
- 9:00>> Exactly, the copper peptide, which is
- 9:02very well studied in skin. You use it in
- 9:04your multi-peptide serum.
- 9:05>> I use copper I love copper peptides.
- 9:08>> I've used it. I bought it. I was like, I
- 9:09got to try this one.
- 9:10>> The peptide serum I put on.
- 9:11>> So, but what what GHK-Cu does, which is
- 9:13amazing, it has it has antioxidant
- 9:15properties. It helps kind of
- 9:17potentially, I have to say potentially,
- 9:19help the way that scars form to be
- 9:21flatter for my patients who are post-op,
- 9:23who don't have a cancer history. I say
- 9:26we can use this as an adjunct tool.
- 9:28>> Mhm.
- 9:29>> And what sets the way I do it apart is
- 9:32that we will do labs. We make sure you
- 9:34don't have a cancer history. In some
- 9:35patients, I'll do even a blood test to
- 9:37make sure they don't have any cancer
- 9:38cells growing. And we'll even do vitamin
- 9:41levels because if you're on the glow
- 9:42stack, it has copper. Copper impacts
- 9:44zinc. And so we need to make sure your
- 9:45zinc levels are okay so that we don't
- 9:47deplete them further or we can make sure
- 9:49to supplement well. And then we we put
- 9:52you on them for a short precise period
- 9:54of time.
- 9:55>> Right.
- 9:55>> It's not like you're indefinitely on
- 9:57indefinitely on this peptide. You're on
- 9:58it for a short precise amount of time
- 10:01with a target in mind. Post-op healing.
- 10:04>> What I see on Instagram is people on
- 10:06GHK-Cu every single day just because for
- 10:08fun, and I'm like, "Mm, there's a cutoff
- 10:09day here." Like you are not going to be
- 10:10on this forever.
- 10:11>> Well, you know, the and the other thing,
- 10:12you know, I've actually had somebody
- 10:14give me um GHK-Cu like a couple years
- 10:18ago just on its own, and I I took it for
- 10:20like two, three days, and I was like,
- 10:22"This burns."
- 10:23>> Burns so bad, right?
- 10:24>> Yeah, it like on its own, and I actually
- 10:25when you had mentioned the glow stack
- 10:26and I looked at the peptides, that was
- 10:28the first thing I said. I was like, "Is
- 10:29this going to hurt?" Cuz I stopped
- 10:30taking it because I didn't like it. But
- 10:33what I like about your process is you're
- 10:34combining the peptides or like you're
- 10:36you're suggesting like a stack so that
- 10:38they're actually working to complement
- 10:40each other and actually give you some
- 10:41sort of benefit or potentially give you
- 10:42that benefit that you're looking for.
- 10:44Whereas like what I am finding with a
- 10:46lot of these people who don't really
- 10:47understand the mechanisms behind these
- 10:50peptides, they're just saying like,
- 10:51"This one gives you a glow. It helps
- 10:52your skin. This one does this." And so
- 10:54you might just be getting piecemeal.
- 10:55Like it's like, "Yeah, they're just
- 10:56giving you a peptide to start
- 10:58injecting."
- 10:58>> And the really important part here is
- 11:01sourcing.
- 11:01>> Mhm.
- 11:02>> Where are the peptides being sourced
- 11:03from?
- 11:04>> Right.
- 11:04>> So
- 11:06it's a legal gray area, and it's always
- 11:08a challenge, but I think things are
- 11:10going to change. What I hear down the
- 11:11rumor mill is that a lot of the peptides
- 11:13are on something called a category two
- 11:15do not compound list.
- 11:16>> Okay.
- 11:16>> There are certain states that have
- 11:17exemptions and are able to produce it.
- 11:19>> Mhm.
- 11:20>> Okay? And so these do not compound
- 11:22lists, basically it means that
- 11:24compounding pharmacies can't make it.
- 11:25>> Right.
- 11:26>> So if a compounding pharmacy can't make
- 11:27it, then you're going to get get it from
- 11:29a gray market, right? Or some research
- 11:31place. I am very meticulous about
- 11:33sourcing and I think as a consumer you
- 11:35need to be aware and say, "Hey, where
- 11:37are you getting this peptide from?" You
- 11:38can still source it from a 503A
- 11:40pharmacy.
- 11:41>> Okay.
- 11:41>> There are stipulations and things, but
- 11:43why do I say get it from an a 503A
- 11:45pharmacy versus research-based pharmacy
- 11:48or research grade pharmacies? Because
- 11:50these 503A pharmacies are being
- 11:52inspected.
- 11:53>> Mhm.
- 11:54>> They are They have to send them out and
- 11:56you can ask like is there third-party
- 11:57testing? Do you have certificates of
- 12:00authenticity? And I have people like on
- 12:02Instagram and they're like, "Oh, I I
- 12:03have a certificate of authenticity from
- 12:05this research pharmacy." And I'm like,
- 12:06"But how do you know they didn't make it
- 12:07on Canva?"
- 12:08>> Right.
- 12:09>> Like how do you know it's legit?
- 12:10>> Yeah.
- 12:10>> How do you know the testing is there?
- 12:11And I just think it's really risky and
- 12:14really gray. So for example, this
- 12:15morning I got an email
- 12:16>> Yeah.
- 12:17>> from a pharmacy
- 12:17>> Okay.
- 12:18>> selling me peptides for like basically
- 12:20something that costs normally like $500
- 12:23for $45.
- 12:25>> Interesting.
- 12:25>> like, "Wow, I mean this is insane. Like
- 12:27what a what a what a price. Like
- 12:29>> You're like, "This is like Groupon."
- 12:31>> like, "What I'm like this can't be
- 12:32real." I literally was like, "This can't
- 12:33be real."
- 12:34So I sent it to my uncle who's a
- 12:36compound pharmacist and I'm like, "Is
- 12:38this legit?" And he's like He's very
- 12:41involved with legislation in the
- 12:43pharmacy world and he's a compound
- 12:44pharmacist himself. So he takes his job
- 12:46very seriously, very responsibly.
- 12:47>> Mhm.
- 12:48>> He takes pride in creating medications
- 12:51for people who need them.
- 12:52>> Right.
- 12:53>> So when he sees pharmacies doing this
- 12:54he's like, "No, these are crazy
- 12:56pharmacies that are popping up taking
- 12:57advantage of this desire for peptides
- 13:01>> Yeah.
- 13:01>> and monopolizing. And then they'll
- 13:02disappear then they'll get a slap on the
- 13:04wrist. They'll make their money and
- 13:05they'll run.
- 13:06>> Right.
- 13:07>> You want a
- 13:08an established long-standing farm
- 13:10pharmacy and as a provider I use a 503A
- 13:12pharmacy and I I know that it might be
- 13:15like something that people desperately
- 13:16feel that a peptide is going to make
- 13:17them feel better.
- 13:19And there are some that are clinically
- 13:20studied and FDA approved and that I can
- 13:22use more flexibly.
- 13:23>> Right.
- 13:24>> And I can touch on those in just a
- 13:25minute.
- 13:25>> Yeah, we will. Yeah.
- 13:26>> But it's not worth your health to risk
- 13:28it on our research-grade peptide. It's
- 13:30just not.
- 13:30>> Yeah, I know. And And by the way, do as
- 13:33I say, not as I do, cuz sometimes I am
- 13:34willing to be like a like a guinea pig
- 13:36and stuff. And you know, like I I think
- 13:38something that people also don't
- 13:39consider is, you know, when I started
- 13:41working with you, you started giving me
- 13:42these itty-bitty
- 13:44needles.
- 13:45>> Yeah.
- 13:45>> my injections, right? That I mean, I
- 13:47didn't get massive needles from the last
- 13:49person that was giving me just like
- 13:50these one-off peptides, you know? But,
- 13:52they weren't the little bitty ones that
- 13:54you were giving me. Like they were a
- 13:55little bit bigger. They're like, you
- 13:56know, just like you're so thoughtful
- 13:58about every
- 13:59>> Yeah.
- 13:59>> step of the process of any kind of
- 14:01injectable that I I think people don't
- 14:03consider that part, either. It's like,
- 14:05you know, that you're They're just
- 14:07getting whatever they can get.
- 14:08>> Right. And I
- 14:08>> Whereas, you're very specific about what
- 14:10you want to give your patient.
- 14:11>> I am. I'm very meticulous. I'm I'm a
- 14:13little upset. I always say like, I know
- 14:14I'm a little control freak. I know I'm a
- 14:15little cuckoo about this, but it's
- 14:17because I always say like,
- 14:19safety, patient safety, your safety is
- 14:20my priority.
- 14:21>> Yeah.
- 14:22>> And it should be whenever we're doing
- 14:23something that's not traditionally the
- 14:25standard of care, because it's not.
- 14:27>> Right.
- 14:27>> So, like there's this one peptide. It's
- 14:29called Well, there's a few, but like one
- 14:30in particular, it's called that TA1,
- 14:33thymosin alpha 1. Thymo- Thymosin alpha
- 14:351, or TA1. I TA1, TA1. We're just going
- 14:38to call it TA1. So, there's TA1. And in
- 14:39other countries, it's approved, and they
- 14:41use it as an adjunct for like hepatitis,
- 14:43for cancer. But, here it's not approved.
- 14:45So, like if you have a patient that's
- 14:47struggling with like immunity, this is
- 14:49potentially a tool that you could bring
- 14:50up to that that I could bring up to
- 14:51them, and I can say, "Hey, look, you
- 14:52keep getting sick. Your or your immune
- 14:54system's garbage. Really, like we need
- 14:56to bolster this immune system. Let Do
- 14:58you want to try this?"
- 14:59>> Yeah.
- 14:59>> That's been used in Europe, in other
- 15:01countries, is approved. Obviously, I
- 15:03talk about all of this with my patients.
- 15:05But, that's a little bit more more of a
- 15:07reasonable option, too, because that's
- 15:09got human studies. Another FDA-approved
- 15:10peptide that I think is amazing that I'm
- 15:12actually on right now.
- 15:13>> You know I'm always on something when
- 15:14I'm here.
- 15:14>> I'm like, "I'm trying this one now." Um
- 15:16it's called SS-31.
- 15:17>> Okay.
- 15:17>> Elamipretide. Elamipretide, SS-31.
- 15:20>> Okay.
- 15:20>> It's actually FDA-approved
- 15:22>> Okay.
- 15:22>> for something called Barth syndrome.
- 15:24>> Okay.
- 15:24>> So that's a condition where young boys,
- 15:27it's a genetic condition in males, they
- 15:28don't have energy in their cells,
- 15:29basically. And this was actually studied
- 15:31and approved in
- 15:33these young males for energy to their
- 15:36cells because it allowed them to walk
- 15:37further and to do more. And this is a
- 15:40fatal condition.
- 15:40>> Okay.
- 15:41>> So granted, I don't use it for patients
- 15:43with Barth, but I use it for people who
- 15:45are struggling with long COVID for
- 15:46fatigue. You know, like if if somebody's
- 15:49got a lot of fatigue, that is a tool
- 15:51that I can say, "Hey, your iron's good.
- 15:53You're eating great. You're sleeping 7
- 15:54hours, but you still feel like you're
- 15:56dragging booty? Like let's try SS-31."
- 15:58And if they are open to trying it, then
- 16:00we'll try it. So that's one that's FDA
- 16:01approved.
- 16:02>> Yeah. Well, you know what I love is that
- 16:03you're never even with me, you're never
- 16:05saying like this is for sure going to do
- 16:07something. You're really just giving
- 16:08like these are alternative options.
- 16:10>> Mhm.
- 16:11>> The you know, like like you just said,
- 16:13you know, it's not like there's that
- 16:14many studies on this or like we've only
- 16:16got animal studies or we've got these,
- 16:17you know, in vitro studies and stuff,
- 16:19but like here's something we can try.
- 16:21And I think that's like the key here is
- 16:23you don't want to go to somebody who's
- 16:25going to be like, "No, this is for sure
- 16:26going to do something for you." Right?
- 16:27>> Yeah. Yeah, because how do I mean,
- 16:29listen, I I don't even know for sure
- 16:32that an antibiotic is going to for sure
- 16:34knock out your UTI unless I get a
- 16:35culture and a sensitivity back and then
- 16:37I know for sure that that antibiotic
- 16:39will work. I think in medicine we have
- 16:41to say there's a science and there's an
- 16:43art and there's the unique person,
- 16:45right? Peptides are a tool in the the
- 16:48landscape of your health.
- 16:50>> Right.
- 16:50>> But they're not the only tool.
- 16:52>> And our health is dynamic, right? Like
- 16:53it's always constantly changing.
- 16:54Sometimes something does fix or like
- 16:56temporarily fix something or helps you
- 16:58through I guess like an issue you're
- 17:00dealing with, but then you start to
- 17:02experience something else or like it
- 17:03needs to change or like you said, you
- 17:04don't indefinitely stay on these
- 17:06injectable peptides, right? Let's talk
- 17:07about some of the I guess popular
- 17:10peptides starting probably with like the
- 17:11GLP-1s because people don't realize that
- 17:14these are a form of injectable peptides
- 17:16that are actually approved and widely
- 17:17used right now.
- 17:18>> Yeah. Yeah, and GLP-1s were first
- 17:19approved for diabetes. They were not
- 17:21approved for weight loss.
- 17:23>> Mhm.
- 17:24>> And that's an off-label use. Yeah, and
- 17:25they started being used off-label for
- 17:27weight loss.
- 17:27>> Mhm.
- 17:28>> Which is probably the most popular way
- 17:29it's being used at this time.
- 17:30>> amazing though. I mean, I think if you
- 17:34use a GLP-1
- 17:36correctly,
- 17:36>> Mhm.
- 17:37>> it's my favorite tool in my toolbox
- 17:39because we have so much safety data.
- 17:41>> Mhm.
- 17:41>> I had a patient with chronic pelvic
- 17:43pain. She had given birth to two kids
- 17:46and she was doing pelvic floor physical
- 17:47therapy and she just had this chronic
- 17:48pelvic pain. She could not walk.
- 17:50>> Mhm.
- 17:51>> She was like, "Every time I walk, I'm in
- 17:51so much pain."
- 17:53We microdosed and I'm talking like 0.25
- 17:56mg of a GLP-1.
- 17:58>> Mhm.
- 17:58>> And I was really I'm like she she was a
- 18:01you know, a
- 18:02normal girl.
- 18:02>> Yeah.
- 18:03>> A normal woman, normal body type, but I
- 18:05was like, "You're not going to lose
- 18:06muscle.
- 18:06>> Yeah.
- 18:07>> You're going to eat the nutrition that
- 18:08you need to eat.
- 18:09>> Yep.
- 18:09>> We did the protein goals. She put on
- 18:11muscle
- 18:12and her pain went away.
- 18:13>> That's because it has anti-inflammatory
- 18:15>> It has anti-inflammatory properties. So,
- 18:17it potentially has anti-inflammatory
- 18:18properties. A lot of patients will
- 18:20report that they feel less puffy, less
- 18:22bloated, and there are some diuretic
- 18:24properties there too. So, one thing that
- 18:27I don't think people realize is when
- 18:28you're on a GLP-1, you need to still
- 18:30hydrate and you have to push hydration.
- 18:32I had an actually really interesting
- 18:33thing because GLP-1s work in the brain
- 18:35and they work in the gut.
- 18:36>> Mhm.
- 18:36>> Right? So, they work in the brain to
- 18:37kind of say, "Hey, impulses of hunger or
- 18:40or, you know, emotional eating and these
- 18:42type of things slow down." And they work
- 18:44in the gut to slow down digestion and
- 18:45they potentially tell your body, "Hey,
- 18:46we need to produce insulin or we don't."
- 18:48So, they work in that way. But, it can
- 18:50actually have like a counter effect,
- 18:52right? So, if you're a person who really
- 18:53really loves eating and the joy of food,
- 18:56I had one patient who was like, "I don't
- 18:57want to be on a GLP-1 anymore." And we
- 18:58were on a microdose and she was like, "I
- 19:00don't want to be on a GLP-1 anymore. It
- 19:01made me sad."
- 19:02>> Oh, we don't
- 19:04>> Yeah.
- 19:04>> And I was like, "Get off that
- 19:05immediately. We will find another way to
- 19:07manage inflammation." Because she was
- 19:09like, "I just don't feel like that
- 19:10excitement that I would get when I would
- 19:12go out to eat and and I'm talking like
- 19:13we were on a baby dose.
- 19:14>> Yeah.
- 19:15>> But
- 19:15>> I'm like if that's like part of being
- 19:17alive too and like we chase longevity
- 19:19and we want health span and lifespan but
- 19:21like we need to live.
- 19:22>> Yeah.
- 19:23>> And if food brings joy, we have to
- 19:25>> Yeah, for sure. Well, you know what's
- 19:26interesting? So so throwing out there
- 19:28also that you got me on tirzepatide but
- 19:31microdosing but the conversation we had
- 19:33and I think that people had these
- 19:34experiences, right? I had said that one
- 19:36time for like a month a while back I had
- 19:39like a friend who's a nurse practitioner
- 19:41give me a semaglutide it was probably
- 19:42like old school Ozempic.
- 19:44>> Yeah.
- 19:44>> And I felt she gave me too much. I felt
- 19:47super sick on it. I hated it. I was like
- 19:49I'm never going to do this again. And
- 19:50then you're like, but first off
- 19:52tirzepatide.
- 19:53>> Yes.
- 19:54>> [laughter]
- 19:54>> And you were like and microdosing it cuz
- 19:56I was like I don't want to necessarily
- 19:57lose weight. I don't want to lose
- 19:58muscle. I don't want to feel like again
- 20:01cuz I also enjoy food and eating and
- 20:02stuff and just also like feeding my body
- 20:04after working out and everything. And I
- 20:06had said that like when I was on the on
- 20:08the Ozempic it just made me feel like I
- 20:10didn't have energy. I felt nauseous. It
- 20:13almost felt like I was pregnant. Like
- 20:15that first trimester of pregnancy where
- 20:16you're just nauseous and sick and even
- 20:18though you're supposed to be eating
- 20:19protein I was eating bread.
- 20:20>> Yeah, yeah.
- 20:21>> What's happening here? Yeah.
- 20:23>> And so I was like that I was like
- 20:24worried about that happening if I ever
- 20:25microdosed
- 20:27any other kind of GLP-1 and then you you
- 20:29were like just try it for your
- 20:31inflammation.
- 20:31>> Yeah.
- 20:32>> I think it's a really common thing that
- 20:34I actually see is patients that have a
- 20:35little PTSD from being started on too
- 20:38high of a dose. So
- 20:39the FDA starting dose of semaglutide is
- 20:410.25 for semaglutide and 2.5 mg for
- 20:44tirzepatide. I will start my patients
- 20:46significantly lower that than that
- 20:48sometimes at 0.5 mg for tirzepatide.
- 20:52I'm not telling you this to experiment
- 20:53on yourself.
- 20:53>> No.
- 20:54>> 0.5 mg of tirzepatide to 1 mg and then I
- 20:57would rather them say to me, I don't
- 20:59really feel anything.
- 21:00>> Yeah.
- 21:00>> But I'll monitor their body composition.
- 21:02>> Yeah.
- 21:03>> And I personally microdose a GLP-1.
- 21:05>> Yeah.
- 21:05>> I found for my undiagnosed autoimmune
- 21:08whatever I have going on, it helps me so
- 21:09much with my joint pain.
- 21:10>> Yeah.
- 21:11>> And I will say that I think people have
- 21:14to be careful because growing up when at
- 21:16a time when skinny was in,
- 21:18>> Mhm.
- 21:19>> like
- 21:20stick skinny was like the only way to be
- 21:22and having a big booty girl is sorry.
- 21:23>> we should be honest and like admit that
- 21:25like with especially with the uprise of
- 21:27like GLP-1s, yeah.
- 21:28>> Yeah.
- 21:29>> Everybody actually, no matter what with
- 21:31body positivity and everything, we can
- 21:33see how people just immediately fall
- 21:35right back into I just want to be a
- 21:37skinny
- 21:37>> Right. And I think like so so definitely
- 21:39like you got to worry about people's
- 21:40mentality and like the psychology behind
- 21:42it and not and make sure that they're
- 21:43not going to go off the deep end.
- 21:45>> And I'm I'm vigilant of that because I
- 21:48want and what I tell everybody is I get
- 21:50it, skinny is kind of trending again.
- 21:52>> Mhm.
- 21:52>> But I don't want you to be skinny.
- 21:53>> Yeah.
- 21:54>> Because what happens when a big booty's
- 21:55back in again?
- 21:56>> Yeah.
- 21:57>> It will come back. Everything comes
- 21:58back.
- 21:58>> never go out of style.
- 21:59>> right? Like so
- 21:59>> Like the massive ones, fine, out of
- 22:01style. But like a healthy juicy butt
- 22:03>> Yeah, like we love the booty, right? So
- 22:05I'm like, I want you to be a strong old
- 22:07lady. Like I want you to be 80 80 90 100
- 22:11and be super strong. Yeah, like guns,
- 22:14you know, booty, like feel like you're
- 22:16not falling off of a toilet seat. And so
- 22:18we can still do that with GLP-1s.
- 22:20>> And I love that you pointed out that
- 22:21like you want people to almost be like
- 22:23it's not like I don't feel anything.
- 22:25I'll throw out there like with the
- 22:26tirzepatide, felt nothing cuz it's such
- 22:27a small dose and I think like you told
- 22:29me to do it like weekly, but I think
- 22:30like at this point cuz I travel so much
- 22:32and stuff, I don't want to take it with
- 22:33me. So I'll do it like every 2 weeks or
- 22:35something like that. And it's like the
- 22:35smallest amount. It's so such a small
- 22:37amount that even when I I I like think
- 22:39about this every time I put the the
- 22:40needle into like pull a little bit out,
- 22:42it's like boop. It's like a little like
- 22:43boop.
- 22:44And then boop, like it just feels like a
- 22:46like it's just very little, but I do
- 22:48overall feel better. Like actually, this
- 22:50is really the only thing I'm doing right
- 22:51now. I had been on the Glow Stack and
- 22:53we'll talk about that next. And then you
- 22:54got me on the microdosing of tirzepatide
- 22:56and I have to say like people are always
- 22:58like, what's your immune system? Like
- 22:59what are you you're for your immune
- 23:00system that you're traveling so much to
- 23:02all these different countries, all these
- 23:04different time zones, and then you get
- 23:06back and you're like not sick. And
- 23:08honestly, I just think it's the
- 23:09tirzepatide.
- 23:09>> I think it helps with the immune system,
- 23:11too. I mean, there's anti-cancer studies
- 23:13on it. Like, there's a lot of benefits
- 23:15to GLP-1s. And so, I think it's just in
- 23:18the way that you use it. And
- 23:20truly, muscle is the organ of longevity.
- 23:22>> Yep.
- 23:22>> Like, I
- 23:23>> 100%.
- 23:24>> So, we don't want to lose that. So, we
- 23:26have to work really intentionally. And
- 23:27I'm not going to lie, like, with your
- 23:28travel schedule, sometimes I think, "Oh
- 23:29my god, I want to put Susan on this."
- 23:30Or, "I want to put her on that."
- 23:31>> Yeah.
- 23:31>> And
- 23:32And like, I have so many ideas. But, you
- 23:33don't need it.
- 23:34>> Yeah.
- 23:34>> So, if you don't need it,
- 23:35>> Yeah.
- 23:36>> it's a tool.
- 23:36>> And you know that I'm going to come to
- 23:37you with questions. I'm going to be
- 23:38like, "Hey, I'm feeling this way." But,
- 23:40like, lately, I mean, a year of working
- 23:42with Mimi, you guys, I feel amazing. I
- 23:43want to talk about some of the most
- 23:44popular peptides. Um, the glow stack is
- 23:47probably one of them. But, you actually
- 23:48you keep mentioning NAD. And I And I do
- 23:50want to talk about that really quickly,
- 23:52just touch on it. Because NAD, I think,
- 23:54is one of those injectables that like
- 23:55got really popular fast. Um, and I
- 23:58remember talking to you about it. And
- 24:00you weren't anti-NAD. You're like,
- 24:02"Let's try it." But, you also were had
- 24:03it like an opinion about it because the
- 24:05information about it's constantly
- 24:06changing. So, let's talk about it.
- 24:07>> I still have an opinion about NAD. So,
- 24:09NAD is not a peptide. It's a coenzyme,
- 24:11right? And we make NAD in our bodies.
- 24:14And as we age, it declines. Right. NAD
- 24:16is great. But, what people don't realize
- 24:18is that you need other vitamins to
- 24:21support the production of NAD.
- 24:22>> Right.
- 24:23>> You need B12. You need folate. There's
- 24:25like a whole I could show you the
- 24:27videos. There's like a whole organic
- 24:28chemistry course that we have to take
- 24:30>> Okay.
- 24:30>> potentially. Like, there's a lot that
- 24:32goes beyond just NAD. And we need a lot
- 24:34in order to produce NAD.
- 24:35>> Mhm.
- 24:36>> So, people are pushing doing NAD, NAD,
- 24:37NAD. But, the problem is that there's no
- 24:39nuance behind it. That they're just
- 24:41giving NAD. And they're not looking at
- 24:43the person's health picture.
- 24:45>> Mhm.
- 24:45>> So, if you don't like, potentially give
- 24:48NAD with B12 or folate or something
- 24:50called betaine, then it could
- 24:52potentially cause an increase in
- 24:54something called homocysteine. And then,
- 24:56that increase in homocysteine is related
- 24:58to not causes but related to negative
- 25:01cardiac outcomes.
- 25:02>> Okay.
- 25:03>> So we need to be careful. And people
- 25:04will say, "Oh my gosh, I got this NAD
- 25:05infusion. I felt so sick. It must be
- 25:08working."
- 25:09>> It must be working. It must be working.
- 25:11>> And I'm like, "Well,
- 25:13>> Yeah.
- 25:13>> actually what happened was that the NAD
- 25:16can sometimes have a a vasodilatory
- 25:18effect, meaning it opens up your blood
- 25:19vessels. And so your heart rate
- 25:21increases and your blood pressure drops
- 25:23and you feel like garbage.
- 25:24>> Yeah.
- 25:24>> There are places and cases and I know
- 25:26clinicians who use NAD for long COVID
- 25:28patients, for Parkinson's patients and
- 25:30they use it for a lot of people. And I
- 25:32will still use NAD. Like if I have a
- 25:34cocktail, which I really do but if I do,
- 25:36the day after, I'll do an NAD shot
- 25:38because alcohol can deplete your NAD
- 25:40levels.
- 25:40>> Right.
- 25:41>> So I'm more like, let's intentionally
- 25:43use this NAD.
- 25:44>> What is the difference between injecting
- 25:46it with just like a needle? The
- 25:48infusions, like the IV infusions cuz I I
- 25:50hear people say all this all the time
- 25:51that they're doing an IV infusion of it
- 25:53this week or something and I'm like, how
- 25:55is that going to help them if they're
- 25:56not doing it like on a daily or weekly
- 25:58basis with injectables, right? With the
- 26:00injection. And then there's also
- 26:01obviously the supplements, right? That
- 26:03you can actually just orally take. Is
- 26:05there a difference or do we not know?
- 26:07>> So there is a difference. It also
- 26:08depends on the peptide. Okay, so let's
- 26:10start with NAD.
- 26:11>> Mhm.
- 26:12>> NAD itself as an oral molecule is too
- 26:14big and your digestive enzymes will
- 26:16break it down.
- 26:17>> Okay.
- 26:18>> So NAD itself orally
- 26:21trash. Right, trash. NMN and NR, these
- 26:24are precursors to NAD and your body
- 26:26converts them. And they're actually very
- 26:28very well studied in humans, NMN and NR.
- 26:31And so those orally
- 26:33>> But probably with a whole stack of other
- 26:36nutrients and vitamins to
- 26:36>> probably want to do like something with
- 26:38betaine, B12, folate but also you want
- 26:41to check your labs because how's your
- 26:43B12? How's your folate? Like, you know?
- 26:45So that's NAD. And then if you do an
- 26:47injection, it's not so aggressive. So
- 26:49anytime you you something through an IV,
- 26:51it's going to feel more potent, right?
- 26:53It's going straight into the vein. When
- 26:55you do an injection into your
- 26:56subcutaneous fat, you're almost creating
- 26:58like a little bleb in the fat that
- 27:01slowly disperses over time.
- 27:03>> Okay.
- 27:04>> I'm a slow and steady kind of girl.
- 27:05Yeah. The turtle won the race anyways,
- 27:07you know, we're going to get there. So,
- 27:08let's get there with tranquility
- 27:11and not palpitations, you
- 27:12>> Right. Right. Right.
- 27:13>> Then BPC 157, that one's made in the
- 27:15gut. Right. So, that's a really cool
- 27:17peptide because that one orally you can
- 27:19take it and the digestive juices don't
- 27:21really break it down.
- 27:22>> Okay.
- 27:23>> That's a really interesting peptide that
- 27:25potentially could be used in patients
- 27:27with like H. pylori, celiacs, uh like
- 27:30stomach issues
- 27:31>> Okay.
- 27:31>> because it reduces inflammation. And so,
- 27:33like when you have an inflammatory gut
- 27:34condition, again sourcing matters,
- 27:37that is a potential peptide that could
- 27:38be beneficial that you can take orally.
- 27:40Okay. But, if you are dealing with like
- 27:42a torn ligament or a knee injury, then
- 27:45we're going to inject that peptide. And
- 27:47there are even some practitioners
- 27:48>> Like locally, like where it's hurting
- 27:49at?
- 27:50>> like, you know, I have a best friend and
- 27:52she pulled her knee. She was like a
- 27:53nothing and she pulled her knee and we
- 27:54did a round of BPC on her knee
- 27:56and she felt better. She didn't have to
- 27:58get surgery. I mean, maybe she will need
- 28:00to eventually, but it did delay it. Now,
- 28:03the question always comes up, is this
- 28:04placebo or is this real life? To which I
- 28:05say, if it works, who cares?
- 28:08>> Right.
- 28:09>> Like truly, you feel better. The mind is
- 28:11powerful. If you this tool allowed your
- 28:13mind to help you heal, then I think
- 28:14that's still a win. But, I guess it
- 28:16depends.
- 28:16>> Yeah.
- 28:17>> Then there's other peptides that so it
- 28:19that you can't do orally because they'll
- 28:21break down.
- 28:21>> Okay. So, it really is kind of dependent
- 28:23on each of these peptides or coenzymes
- 28:25or everything.
- 28:26>> Yeah. And NAD itself is just a really
- 28:28big molecule. There's even the theory of
- 28:30like it's so big, even if you inject
- 28:32NAD, does it really raise your plasma
- 28:34levels of NAD? And that's a question
- 28:36mark. But, there's now a conversation
- 28:38around something called CD38 and CD38
- 28:42actually degrades or breaks down your
- 28:44NAD. So, if If can come up with
- 28:45something that says to CD38, "Hey, stop
- 28:48breaking down NAD." then we can
- 28:49naturally boost NAD levels.
- 28:51>> Mhm.
- 28:52>> another cool tool. We just don't have
- 28:53that yet.
- 28:53>> Yeah. You know, you bring up another
- 28:55point of like why it's important to work
- 28:57with a real practitioner like you, like
- 28:59a medical practitioner, while you're
- 29:00doing any of these types of injectables
- 29:02and it's because the the information is
- 29:04constantly changing, especially as it
- 29:05becomes more popular. Like you saying
- 29:07that now there's a study happening in
- 29:08China with these peptides and stuff.
- 29:10It's like it's obviously becoming more
- 29:11popular. There might be more studies
- 29:13that come out. More information will
- 29:14absolutely come out, whether it's good
- 29:16or bad information, as everything
- 29:18changes and it's it's really important
- 29:20to have someone like you to keep your
- 29:22patients informed about stuff that
- 29:24they're taking, right?
- 29:25>> Yeah.
- 29:26>> So.
- 29:26>> Oh, and now you just made me remember
- 29:27TB4. There's actually a study um in dry
- 29:30eyes, so eye drops that you can
- 29:32potentially use for dry eyes and that's
- 29:33a phase two, phase three trial in dry
- 29:35eyes as we get older, like I don't know,
- 29:36I have dry eyes all the time and I wear
- 29:38contacts. So, I this is a very promising
- 29:41interesting use of TB4. That's why it's
- 29:43like it's not that it's
- 29:46dangerous or crazy or experimental. It's
- 29:48a little bit of both, depending on how
- 29:49you use it.
- 29:50>> [laughter]
- 29:51>> Right. It depends on how it's used, you
- 29:53know?
- 29:53>> Right. Right.
- 29:54>> So, I don't know. It's
- 29:55>> So, going to a medical professional is
- 29:56probably key number one.
- 29:58>> Yes, I think going to a medical
- 29:59professional is important.
- 30:01>> Let's touch on uh the glow stack has
- 30:02three different peptides and I feel like
- 30:04I see a lot of people on them. I did
- 30:06mine for like two and a half, three
- 30:07months almost and this was post surgery.
- 30:09So, this is what you suggested post
- 30:10surgery.
- 30:11Let's tell everybody what these these
- 30:13peptides do.
- 30:13>> So, the glow stack is a combination of
- 30:15three peptides, BPC 157, TB4, and
- 30:19GHK-Cu. The pharmacy that I use that
- 30:21makes it actually tests that the
- 30:23potency, meaning that they all still
- 30:25work when they're combined. Because
- 30:26sometimes when you combine these
- 30:27peptides, they actually don't work.
- 30:29>> Right.
- 30:29>> They inactivate each other because they
- 30:31require different pHs. So, it's
- 30:32important to know that if they're
- 30:34combined, were they tested for potency?
- 30:36>> Yeah.
- 30:36>> And they were.
- 30:37>> Right.
- 30:38>> And actually I'll point out in skin care
- 30:40for Naturium, when we use our copper
- 30:41peptides we encapsulated the copper
- 30:43peptides because copper peptides since
- 30:45they act like antioxidants can actually
- 30:47be very unstable. So that's a good point
- 30:49to bring up to people.
- 30:50>> Yeah.
- 30:50>> And the studies on GHK-Cu topical in a
- 30:52nano lipid carrier are how they
- 30:55penetrate the skin. So when I saw that
- 30:57Naturium had it made that way of course
- 30:59I bought it.
- 31:00>> So that glow stack is really great for
- 31:02>> It's great for I like to use it post-op
- 31:04or post injury.
- 31:06>> Mhm.
- 31:06>> Because for example if you have a breast
- 31:08implant I used it for my I had an
- 31:11explant done and I did it for my breast
- 31:13explant and my surgeon was like your
- 31:14scars healed so well. Now granted I also
- 31:17did hyperbaric oxygen I did the peptide
- 31:20and I did my very nutritious high
- 31:23protein diet right?
- 31:24>> Right.
- 31:24>> So people who have an injury what it
- 31:26could potentially do is it decreases
- 31:28inflammation.
- 31:29>> Mhm.
- 31:29>> It tells your fibroblasts and basically
- 31:33like collagen and blood vessels to
- 31:36regenerate.
- 31:37>> Mhm.
- 31:37>> So it has does something potentially
- 31:38called angiogenesis which is the growth
- 31:40of new blood vessels and that's where we
- 31:42go could this cause cancer?
- 31:43>> Right.
- 31:44>> have to be careful.
- 31:45And then GHK-Cu oh my gosh it's so cool
- 31:47in theory the mechanism of GHK-Cu it
- 31:50communicates with the cells and it can
- 31:52either upregulate or downregulate cells
- 31:54meaning it can either tell them to
- 31:55behave or not behave in certain ways to
- 31:58your genes. And so it has this really
- 32:00powerful anti-inflammatory antioxidant
- 32:02communication kind of throughout our
- 32:03body. And so we use it or I use it
- 32:07post-op.
- 32:08>> Okay. That
- 32:08>> to support the healing.
- 32:09>> We've also heard about the Wolverine
- 32:11stack on social media. What is this one?
- 32:12>> Okay. Wolverine stack. No it's awesome.
- 32:14Wolverine stack is great and I will use
- 32:16it in patients with like a
- 32:18musculoskeletal or soft tissue injury.
- 32:21It's awesome. Orthopedic surgeons often
- 32:23use it and they actually used it before
- 32:25I used it. Not all orthos use it but
- 32:28some orthos use it. Dr. William Seeds is
- 32:30an orthopedic surgeon turned peptide
- 32:32guru educator and he he even talks about
- 32:35how he used this and he used collagen
- 32:38and different modalities to help heal
- 32:39his patients and he was like I didn't
- 32:40need surgery and so I changed what I was
- 32:42doing. But it's BPC 157 and TB4. They
- 32:45work together with angiogenesis,
- 32:47anti-inflammatory, wound healing
- 32:50and it's a great tool in the toolbox.
- 32:51>> Right.
- 32:52>> And and
- 32:52>> But it it's just removing the
- 32:54>> The GHK-Cu.
- 32:55>> Yes, the no copper peptides
- 32:56>> Yeah, no copper peptides which for me if
- 32:59I have a patient that I haven't been
- 33:01able to do really recent labs on
- 33:03>> Yeah.
- 33:03>> maybe that would be a good choice
- 33:05because we know that I don't need to
- 33:07know what their copper levels look like.
- 33:08>> Right. Right, right, right.
- 33:09>> What do their zinc levels look like? I
- 33:10can put them on this BPC 157, Wolverine
- 33:12stock, TB4. We have very minimal human
- 33:15studies on BPC 157. We have like two or
- 33:18three.
- 33:18>> Right.
- 33:18>> There's one clinical trial going on
- 33:19right now and then TB4 we have a few
- 33:21human studies in other countries too but
- 33:23like we always could use more studies
- 33:25but who's going to who's doing it?
- 33:27>> And it's already making money so it's
- 33:28always that's actually the issue, right?
- 33:30>> That's the issue, yes.
- 33:30>> Tesamorelin?
- 33:31>> Oh, I love tesamorelin. So tesamorelin
- 33:34is
- 33:34>> Tesamorelin?
- 33:36>> Tesamorelin. But I I mean that's the way
- 33:37I say it. Basically communicates with
- 33:41your brain to tell your body to produce
- 33:43more growth hormone.
- 33:44>> Okay.
- 33:44>> And it's actually FDA approved for HIV
- 33:47lipodystrophy. So lipodystrophy means
- 33:50like your fat is not where it should be
- 33:52and particularly in the belly fat
- 33:54visceral organs and so that is a peptide
- 33:56that I will use in my patients
- 33:57off-label.
- 33:58>> Mhm.
- 33:59>> And so people will be like oh these are
- 34:00all not FDA approved but if you only
- 34:02want to do what's FDA approved we can
- 34:04absolutely use FDA approved peptides and
- 34:06your clinician should know the
- 34:07difference of what's FDA approved like
- 34:09tesamorelin which is FDA approved in
- 34:11patients with lipodystrophy who have HIV
- 34:14a very specific population but we can
- 34:15use it off-label in patients who don't
- 34:18have HIV, who have belly fat, who have a
- 34:21low IGF-1, who are having a hard time
- 34:24losing fat and putting on muscle. Now it
- 34:26can cause bloating, it can cause water
- 34:28retention and in some cases it can cause
- 34:30blood sugar to rise and so we look at
- 34:33labs because we need to monitor that.
- 34:34The reason why GHK-Cu is so popular is
- 34:37because it hits so many things.
- 34:39Performance, oh my gosh, it can help
- 34:41with my antioxidant capacity, it's
- 34:43anti-inflammatory, it helps with my
- 34:45skin. And so it has a lot of promise.
- 34:48>> Right.
- 34:48>> But I want to see what the actual proof
- 34:50is and I think we see that over time.
- 34:51CJC, did we talk about that? Oh, we
- 34:52didn't, but CJC is similar to
- 34:54Tesamorelin that it communicates with
- 34:55the brain to produce more growth
- 34:57hormone. Right now it's on the do not
- 34:58compound list. There was and there have
- 35:00been human clinical trials on it. There
- 35:03was one death associated with one of the
- 35:04clinical trials, but it wasn't related
- 35:06to that.
- 35:07>> Okay.
- 35:08>> So but it's it's again potentially for
- 35:10muscle building, but I'm always like,
- 35:12well, we can use the Tesamorelin which
- 35:14is FDA approved and a little bit more
- 35:17>> has more studies on
- 35:17>> more studies.
- 35:18>> Okay. So if somebody's saying CJC, ask
- 35:20more questions.
- 35:21>> Yeah, but it's still a good option.
- 35:22>> It's still a good option.
- 35:23>> yeah, it's still a good option. It's
- 35:24just again harder to source safely. Some
- 35:26pharmacies don't want to produce it
- 35:27because of
- 35:28>> the studies
- 35:29>> the gray area and the legalities, but
- 35:30hopefully things will be changing and
- 35:32rumor has it that peptides will be
- 35:34moving from category two to category
- 35:35one, which means that we'll be able to
- 35:36compound them again. And the reason why
- 35:38that's happening is because
- 35:39>> They're already off-label, gray market.
- 35:42>> Yes, a friend of mine sent me a picture
- 35:43of she lives in California, she was at
- 35:44the gym and they're literally selling
- 35:46vials of peptides at her gym.
- 35:47>> Shut up.
- 35:48>> But she could lose her license if she
- 35:49prescribes them.
- 35:50>> Right. That's ridiculous.
- 35:51>> Tell me
- 35:52>> Make it make sense.
- 35:52>> Make it make sense.
- 35:53>> Make it make sense.
- 35:54>> Make it so that the actual medical
- 35:55practitioners can do it.
- 35:56>> Yeah, safely.
- 35:57>> TA1, did we talk about that?
- 35:58>> Oh, yeah. So Thymosin alpha 1, that's
- 36:00the one that's been studied in other
- 36:01countries that's immunomodulatory. So it
- 36:03can help potentially with immune
- 36:06function and as we age our thymus gland
- 36:09gets smaller and so it can support that.
- 36:11So say that you're traveling a lot and
- 36:12you're getting sick, that would be a
- 36:14good tool that we could put in the
- 36:14toolbox.
- 36:15>> All right.
- 36:16>> It's used it for hepatitis and in other
- 36:18countries it's approved, but it's just
- 36:19not approved here.
- 36:20>> And then as far as longevity goes, how
- 36:22do peptides fit in? Like are all of
- 36:24these peptide these injectable peptides
- 36:25basically for longevity?
- 36:27>> So I think they could be a tool in your
- 36:29toolbox. Are they going to replace a
- 36:31strong diet and exercise?
- 36:34>> No.
- 36:34>> Right. They're a tool. They can support,
- 36:36but not replace
- 36:37>> Mhm.
- 36:38>> the essentials, which are diet and
- 36:40exercise. And I think that they can help
- 36:41in really acute situations like long
- 36:43COVID or Parkinson's or they can add
- 36:46quality of life potentially for somebody
- 36:48who has like a knee injury, but really
- 36:49enjoys playing pickleball.
- 36:51>> Right. And gets relief from it. How
- 36:52about for anti-aging? Like for the
- 36:54actual like skin and look and your hair
- 36:55and everything?
- 36:56>> I would love to say yes, but I I think
- 36:58we need more studies
- 36:59>> Yeah.
- 36:59>> to say that it actively works. We know
- 37:01GHK-Cu topically can improve collagen. I
- 37:04think it there was a study done with
- 37:05GHK-Cu, vitamin C, and tretinoin and
- 37:08GHK-Cu had better outcomes than both
- 37:10vitamin C and tretinoin.
- 37:11>> Oh, that's interesting.
- 37:12>> Yeah. But I don't know if I would get
- 37:14rid of my tret and my vitamin C. I think
- 37:15I might just add it to the mix, right?
- 37:16Cuz it helps boost collagen. But again,
- 37:18I think it's part of a bigger picture,
- 37:20right? You can use the GHK-Cu and maybe
- 37:22if you're open to being a guinea pig and
- 37:23experimenting with yourself safely with
- 37:26the right sourcing, maybe you try a
- 37:27cycle of the GHK or the glow stack
- 37:29cautiously knowing that there are risks
- 37:31and that there's not enough studies and
- 37:33see how you feel with your skin. But do
- 37:36I think it's going to replace Sculptra,
- 37:38laser, and facelifts? No.
- 37:39>> Right. Of course not. Of course not.
- 37:41>> I'm going [laughter] to get mine, you
- 37:42know? I don't
- 37:42>> For sure, 100%. So, I guess to end this
- 37:44conversation about injectable peptides,
- 37:46we know people are going to go out and
- 37:49and try to get peptides. It's so
- 37:50popular. I see conversations about it
- 37:52pop up every single day.
- 37:54What should people be looking for when
- 37:56they are trying to source it? Like if
- 37:58whether it's with a medical practitioner
- 37:59or with somebody else that like sells it
- 38:01online or something, what questions
- 38:03should they be asking?
- 38:04>> I think we need to have people ask about
- 38:06sourcing.
- 38:07>> Mhm.
- 38:07>> So, where is this peptide coming from?
- 38:09Is it coming from a 503A pharmacy? Is it
- 38:11coming from a research use only
- 38:13pharmacy? If it is coming from a
- 38:14research use only pharmacy, that's a red
- 38:16flag.
- 38:17>> Mhm.
- 38:17>> I wouldn't do it. If your medication has
- 38:19any particulate in it, if it's chunky,
- 38:22don't use it. Right? If it's foamy,
- 38:23don't use it. Right? I mean, I would
- 38:25just say work with a educated clinician
- 38:28who's not afraid of the hard questions,
- 38:29who can tell you, "I don't know. Let me
- 38:30look that up." Cuz that's a superpower
- 38:32to be able to say, "I don't know. I can
- 38:33look that up." We don't know it all.
- 38:35This is an evolving field. Sourcing is
- 38:37really important because I am seeing a
- 38:38lot of people get it from just random
- 38:41places online and they're not asking
- 38:43enough questions.
- 38:44>> Yeah. How about if somebody's just
- 38:46recommending like one peptide to you? Or
- 38:48if you go to a person that's selling it
- 38:50and you're like, "I just I want to be on
- 38:52copper peptides. I I just give that to
- 38:54me." And they're like, "Okay." Is that a
- 38:55red flag?
- 38:56>> For me, yes. Because I know that it can
- 38:59impact zinc levels. If you're not
- 39:01looking at your patient's zinc levels,
- 39:03that's really important because zinc and
- 39:04copper can impact the way your blood
- 39:07cells form.
- 39:08So, for example, patients who have
- 39:09chronically low white blood cell count,
- 39:11sometimes you'll check their copper and
- 39:12their zinc and they'll have low copper.
- 39:14And when you address the low copper,
- 39:16their white blood cells improve.
- 39:18I think it's a red flag.
- 39:19>> Yeah. Yeah. Like they need a maybe even
- 39:21potentially check your labs. Say they
- 39:23need need to check your labs, but also
- 39:25maybe even suggest other things or
- 39:26stacks.
- 39:27>> Yes. Or like, how are you eating,
- 39:29sleeping, pooping?
- 39:31>> [laughter]
- 39:31>> Like all the main health questions
- 39:33first.
- 39:33>> If someone's not asking about those core
- 39:36functions, yeah. And they're just trying
- 39:38to sell you a peptide and they If
- 39:40someone tells you that a peptide is
- 39:41going to do it all, you run. Right? It's
- 39:43not going to do it all. You'll need to
- 39:44do the work. The peptide's just going to
- 39:46I always say it's sprinkles. You're the
- 39:48cake that have to be baked. And you got
- 39:50to be frosted. Then we can throw the
- 39:51sprinkles on top.
- 39:52>> Yeah, that makes sense. They're a tool,
- 39:53like you keep saying. I I really like
- 39:55that you're referring to injectable
- 39:57peptides as a tool because I think
- 39:58that's what people need to remember.
- 39:59They're a tool in the overall toolbox.
- 40:02And that's it.
- 40:02>> and they're not going to replace
- 40:04the daily behaviors that you have to do
- 40:06that are work.
- 40:06>> Being healthy.
- 40:07>> Yeah.
- 40:08>> Yeah. Maymay, thank you so much. We
- 40:10could talk about this forever. So, and
- 40:11and like I you sitting here, I already
- 40:13have like other things I've heard about
- 40:14and everything and I want to ask you
- 40:15questions and stuff. So, I'm just going
- 40:17to end this conversation right here and
- 40:19I'm sure people will have more
- 40:19questions, so we can always have you
- 40:20back.
- 40:21>> Thank you, Susan. I love chatting with
- 40:22you.
- 40:23>> I love chatting with you. Where can
- 40:24people find you?
- 40:25>> Oh, people can find me at Revere
- 40:27Wellness or we actually started a
- 40:29podcast too, inspired by you.
- 40:30>> Love it.
- 40:31>> plug it, it's called the Revere Rundown.
- 40:32>> Yep.
- 40:33>> It's basically answering common
- 40:34questions that we get from our patients.
- 40:36>> Yep.
- 40:36>> And I have a very boutique practice. I
- 40:39like to know all of my patients by name,
- 40:41their kids, what they do, where they
- 40:42are, like their lives. And so, in order
- 40:44to touch more lives and truly my
- 40:46delusional goal of like changing
- 40:48people's lives for the better, I
- 40:49launched this podcast called the Revere
- 40:51Rundown to hopefully help others live
- 40:52better.
- 40:53>> Yeah, and you know, really quickly, I
- 40:54think cuz we were talking about
- 40:56about injectable peptides, but that's
- 40:57not what you really focus on.
- 40:59>> Yeah.
- 40:59>> Will you just tell everybody why they
- 41:00would want to maybe work with you?
- 41:02>> Yeah. Oh, thank you. So, I focus on an
- 41:04inside-out approach to wellness. That
- 41:07looks differently for everybody, but
- 41:08it's usually by looking at like hormone
- 41:10optimization,
- 41:11how you're pooping, how you're sleeping,
- 41:13how you're eating, and then how we can
- 41:15optimize your life. I truly want my
- 41:16patients to have like the strong old
- 41:19lady body, strong old man body cuz I see
- 41:21their husbands too sometimes
- 41:22occasionally. I primarily work with
- 41:24women, but they're always like my
- 41:25husband's jealous or my boyfriend's
- 41:26jealous. Can he come see you? My son
- 41:27wants to come see you. And then I'm
- 41:28like, of course, you know, cuz we treat
- 41:29the whole family.
- 41:30>> Yeah, I focus on an inside-out approach.
- 41:32I truly believe that if you're healthy
- 41:33on the inside, not just your body, but
- 41:35your mind,
- 41:36then it shows on the outside and that's
- 41:39what we do, optimal wellness that way.
- 41:41>> Thank you so much.
- 41:42>> Thank you, Susan. I appreciate it.
- 41:44>> Thanks for watching this episode of Glow
- 41:45Lab. If you enjoyed it, make sure you
- 41:47subscribe, rate and review, and of
- 41:48course, share it with a friend that way
- 41:50we can keep the conversation going with
- 41:51amazing guests.
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