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The Truth About Peptide Injections: GLP-1s, BPC-157, GHK-Cu, & What They Do for Your Skin & Body — Transcript

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  1. 0:00I think if you use a GLP-1 correctly,
  2. 0:03>> Mhm.
  3. 0:04>> it's my favorite tool in my toolbox.
  4. 0:06>> Yeah.
  5. 0:07>> Because we have so much safety data. I
  6. 0:09had a patient with chronic pelvic pain.
  7. 0:11She had given birth to two kids, and she
  8. 0:13was doing pelvic floor physical therapy,
  9. 0:15and she just had this chronic pelvic
  10. 0:16pain. She could not walk.
  11. 0:17>> Mhm.
  12. 0:18>> She was like, "Every time I walk, I'm in
  13. 0:19so much pain."
  14. 0:20We microdosed, and I'm talking like 0.25
  15. 0:23mg of a GLP-1.
  16. 0:25>> Mhm.
  17. 0:25>> And I was really I'm like she she was a
  18. 0:28you know, a
  19. 0:29normal girl.
  20. 0:30>> Yeah.
  21. 0:30>> Normal woman, normal body type, but I
  22. 0:32was like, "You're not going to lose
  23. 0:33[music] muscle.
  24. 0:34>> Yeah.
  25. 0:34>> You're going to eat the nutrition that
  26. 0:35you need to eat."
  27. 0:36>> Yep.
  28. 0:36>> We did the protein goals. She put on
  29. 0:39muscle,
  30. 0:40and her pain went away. Welcome to Glo
  31. 0:41Lab. We're going to have a lot of fun
  32. 0:43and learn a lot together.
  33. 0:46Peptide injections are really popular,
  34. 0:47especially on social media. But, I think
  35. 0:49it's really important to know that they
  36. 0:51are experimental. There aren't a lot of
  37. 0:53human studies, and [music] where you're
  38. 0:54getting it really matters. That's why my
  39. 0:57guest today is Mimi Deal. She is a
  40. 0:58board-certified nurse practitioner.
  41. 1:00[music] She's also the founder of Rebel
  42. 1:01Wellness here in Miami, where she really
  43. 1:03focuses on functional health, especially
  44. 1:05for women. I happen to be one of her
  45. 1:06patients, and I go to her because I have
  46. 1:09autoimmune diseases like my Hashimoto's,
  47. 1:11and I also work with her on my hormones.
  48. 1:13And one aspect that we work together on
  49. 1:15is peptide injections, and whether I
  50. 1:16actually need them or not. So, I really
  51. 1:18think this is an informational
  52. 1:19conversation for anyone that is
  53. 1:21considering peptide injections, because
  54. 1:23there's a lot to know about them. Mimi.
  55. 1:25>> Hi.
  56. 1:25>> Second time back.
  57. 1:27>> [laughter]
  58. 1:28>> You guys, this is one of my favorite
  59. 1:30people ever ever. I've been working with
  60. 1:33her for an entire year now, ever since
  61. 1:35you came onto the podcast, and we've
  62. 1:36been working on just like I mean,
  63. 1:37everything. We look at everything that's
  64. 1:39going on with my body.
  65. 1:40>> Everything.
  66. 1:41>> Yeah.
  67. 1:41>> Inside out. Like, it's so important to
  68. 1:43look at the whole picture. And you're
  69. 1:45very health knowledgeable. So, when I
  70. 1:47work with patients who know different
  71. 1:48things that are out there, like you send
  72. 1:50me things on Instagram, and I think you
  73. 1:51send me different peptides, and
  74. 1:53different
  75. 1:53>> waiting for me sometimes to send you
  76. 1:54something that you've already launched.
  77. 1:56Yeah.
  78. 1:56>> I'm like, "How many patients are going
  79. 1:57to send me this? I love it so much. But
  80. 1:59I love it because it opens the
  81. 2:00conversation. And patients nowadays,
  82. 2:02like I hate to say this, but it's true.
  83. 2:05The medical industry has changed.
  84. 2:07Whether you're going to a hospital or
  85. 2:10small offices, they're businesses. The
  86. 2:12big hospitals are businesses, the small
  87. 2:13offices are still businesses, and you as
  88. 2:15a patient need to be an educated
  89. 2:17consumer. In the same way you research
  90. 2:19your blush, your mascara, who's going to
  91. 2:21go color your hair, research who you're
  92. 2:23going to go see.
  93. 2:24>> Yeah. For sure, especially for today's
  94. 2:26topic because we are talking about
  95. 2:27specifically injectable peptides.
  96. 2:30>> Yes.
  97. 2:30>> Which is funny because last time we had
  98. 2:31you on the podcast, we talked more about
  99. 2:33like menopause and overall women's
  100. 2:35health, like functional health. But this
  101. 2:37topic I feel like over the last year has
  102. 2:39really exploded because I asked you
  103. 2:40about it and you're like, well, it's
  104. 2:42still experimental, like it's hard to
  105. 2:43get them sometimes, the you know, like
  106. 2:45there were all these like challenges.
  107. 2:47But now it suddenly it feels like you
  108. 2:48can get them anywhere.
  109. 2:50>> Well, that's the dangerous thing, to be
  110. 2:51honest. So, we touched on NAD last time.
  111. 2:54And that we could do a whole episode on,
  112. 2:56but in general peptides, what happened
  113. 2:59was that peptides are old medicine.
  114. 3:01Insulin is a peptide. Oxytocin, the
  115. 3:03hormone that you release when you have
  116. 3:05an orgasm, when you have a contraction,
  117. 3:08that's a peptide. Peptides are basically
  118. 3:10First, I want to start by saying like,
  119. 3:11what is a peptide, right? Yeah. So,
  120. 3:12peptides are amino acids. Amino acids,
  121. 3:16think of them as letters in the
  122. 3:17alphabet. Then, when amino acids come
  123. 3:20together, they form a peptide, which is
  124. 3:22a word. And then, when you have a lot of
  125. 3:24words together, you get a sentence or a
  126. 3:26protein. So, many many uh peptides
  127. 3:28become a protein. So, that's what a
  128. 3:29peptide is. A peptide is an amino acid,
  129. 3:32and it sends a message to your body.
  130. 3:34>> Right.
  131. 3:34>> Your body naturally makes peptides. We
  132. 3:37produce 300 peptides. Insulin is a
  133. 3:40life-saving peptide. GLP-1, semaglutide,
  134. 3:43Ozempic, Mounjaro, tirzepatide, all
  135. 3:45peptides. So, peptides have been around
  136. 3:47for a while. They've also been used in
  137. 3:50off-label ways. So, like bodybuilders
  138. 3:53kind of started using them first
  139. 3:55experimentally in themselves.
  140. 3:56>> I actually think of it's for me, it was
  141. 3:58bodybuilders who started talking to me
  142. 4:00about peptides. It was a lot of like
  143. 4:02when I was working out with my personal
  144. 4:04trainers and all that and I would say to
  145. 4:05them like, "Why aren't I growing muscles
  146. 4:07faster?" Or, you know, like, "Why do I
  147. 4:10Why do I feel so weak?" Or like, "How do
  148. 4:11I get like a more, you know, like
  149. 4:13voluminous body over the next 2 months
  150. 4:15and stuff?" And they would say, "Well,
  151. 4:17you know that this person that you're
  152. 4:18showing me on Instagram is likely on
  153. 4:20some kind of a peptide.
  154. 4:21>> Yeah.
  155. 4:22>> Right?
  156. 4:22>> So, they started. Like, I I think they
  157. 4:24started with the bodybuilding world,
  158. 4:25right? Kind of like the way that things
  159. 4:27were secret, black market, you know,
  160. 4:29like behind the scenes your trainer
  161. 4:30would give them to you, whatever, you
  162. 4:31know, like there was less regulation.
  163. 4:33Then there was like a popularity that
  164. 4:36came out. Yeah, peptides became more
  165. 4:37popular. With that popularity, grifters
  166. 4:39came into the world and they started
  167. 4:41saying like,
  168. 4:42"Yes, I can make money off of a person.
  169. 4:44I can tell them that this is the
  170. 4:46end-all, be-all, that, "Oh my gosh, with
  171. 4:47this peptide you are going to have the
  172. 4:48tightest ass you've ever had. I'm going
  173. 4:50to give you this mister morlin your butt
  174. 4:52will bounce like it's never bounced,
  175. 4:54right? Like it's going to be amazing.
  176. 4:55>> Yep.
  177. 4:56>> But what happens is
  178. 4:57people who look at peptides like that
  179. 4:59are selling you a lie.
  180. 5:00>> I do want to throw out there, I have
  181. 5:02been on different peptides. And the
  182. 5:03first time I ever got on injectable
  183. 5:05peptides was with one of my personal
  184. 5:07trainers in the past. And that was
  185. 5:09because I had complained about not
  186. 5:11growing muscle. But then when I met you
  187. 5:12and we started talking about like HRT
  188. 5:14and everything, it, you know, it turned
  189. 5:16out it could also be something like, I
  190. 5:18mean, women just don't naturally
  191. 5:20>> It's hard to grow muscle.
  192. 5:20>> muscle, right? And so and so we started
  193. 5:23talking about like hormone replacement
  194. 5:25therapy and everything too is another
  195. 5:26way to to really build your muscle. So,
  196. 5:29I do want to point out there are
  197. 5:30different ways to do that. But something
  198. 5:32I think that was really interesting in
  199. 5:34working with you, you've always been
  200. 5:35very, I guess, methodical about it and
  201. 5:37thoughtful about peptides. Like if I
  202. 5:39bring up a peptide to Mimi, you're kind
  203. 5:41of like, "No, well, let's talk about
  204. 5:43what could be the side effects of this?"
  205. 5:45Or, you know, like issues when we need
  206. 5:46to make sure we do your labs to make
  207. 5:48sure that you're okay to do this because
  208. 5:50you know, there there could be things
  209. 5:51that happen. So can we talk about that a
  210. 5:53little bit?
  211. 5:53>> Absolutely. So when it comes to peptides
  212. 5:55and I think this is how you're going to
  213. 5:56know if you're working with a
  214. 5:57responsible peptide provider. We look at
  215. 5:59them in terms of systems. Like whenever
  216. 6:02someone asks me about a peptide, I say
  217. 6:03what what are we going to do with it?
  218. 6:05Like what's the purpose? Are we working
  219. 6:06on metabolism? Are we working on, you
  220. 6:09know, weights, body composition, muscle
  221. 6:11building? Are we working on your immune
  222. 6:13health? What what are we working on?
  223. 6:15Right? So like let's pick like our goal.
  224. 6:18And then we have to do labs. I firmly
  225. 6:20believe we have to do labs because
  226. 6:22a lot of these peptides, we only have
  227. 6:25animal studies and we only have in vitro
  228. 6:28studies, meaning in a test tube, in a
  229. 6:30little petri dish, right?
  230. 6:31>> dish, right? Or it's not an actual
  231. 6:33human. It's just seeing what it does to
  232. 6:34cells that sit inside a petri dish,
  233. 6:36right? Which is like so powerful.
  234. 6:39>> But that doesn't always translate.
  235. 6:40Right. So then we say, okay, this is
  236. 6:42going to be an N of one, a study of one.
  237. 6:45Because I do believe medicine is
  238. 6:46personalized. There is no other human
  239. 6:49being on this planet like you. Right?
  240. 6:51Right? Like you are just you and there's
  241. 6:53no one like you. I feel like Dr. Seuss
  242. 6:54every time I say it, right? So
  243. 6:56I'm going to look at your labs. I'm
  244. 6:58going to say, what is your personal
  245. 7:00history?
  246. 7:01>> Yeah.
  247. 7:01>> Do you have a history of cancer? Because
  248. 7:03then unfortunately, you're probably not
  249. 7:05going to be a candidate for a lot of
  250. 7:06peptides that would stimulate growth.
  251. 7:09Like some popular ones you hear on
  252. 7:11social media are BPC 157, okay? That's
  253. 7:14body protective compound 157. And that
  254. 7:17one, we really have minimal human
  255. 7:19studies on.
  256. 7:20>> Mhm.
  257. 7:21>> It's one of the most popular ones. I
  258. 7:22think it's because it's really benign in
  259. 7:25what it could do if it was bad. What we
  260. 7:27do see of the good is good.
  261. 7:28>> What's the good?
  262. 7:29>> It's anecdotal. So it's
  263. 7:30anti-inflammatory potentially.
  264. 7:31>> Okay.
  265. 7:32>> It's made in our gut.
  266. 7:33>> Oh.
  267. 7:33>> BPC is a peptide that we produce
  268. 7:35naturally in our gut.
  269. 7:36>> Okay.
  270. 7:36>> And now there's actually a a clinical
  271. 7:39trial going on in China
  272. 7:41>> Okay.
  273. 7:41>> for some muscle injury, I can't remember
  274. 7:44the exact specifics. There's also
  275. 7:46another small, not a perfect trial that
  276. 7:48was done here in the US by a physician
  277. 7:50here in the US, a small study where he
  278. 7:52injected BPC into patients' knees who
  279. 7:55were complaining of knee pain, and they
  280. 7:57reported improvement of pain.
  281. 7:58>> Okay.
  282. 7:58>> Then we have animal studies.
  283. 8:00>> Right.
  284. 8:01>> I personally have used BPC on myself.
  285. 8:02>> Okay. How have you used it?
  286. 8:04>> Yes.
  287. 8:04>> Okay.
  288. 8:05>> [laughter]
  289. 8:06>> I can't even remember at this point.
  290. 8:07>> You have. So, I personally think about
  291. 8:09how I use it very intentionally, very
  292. 8:11carefully. So, I'm going to go on to
  293. 8:13Glow Stack, and then we'll talk about
  294. 8:14how I used it.
  295. 8:15>> Right. That's when I used it.
  296. 8:16>> You did Glow Stack post-op.
  297. 8:18>> Mhm.
  298. 8:18>> So, I use Glow Glow Stack post-op
  299. 8:20because the mechanism behind why we're
  300. 8:23using it is what matters here. And we
  301. 8:25know in a conversation that we had very
  302. 8:28openly that, look, this is not going to
  303. 8:30replace you eating
  304. 8:32really well post-op.
  305. 8:33>> Mhm.
  306. 8:34>> It's not going to replace you sleeping
  307. 8:35post-op, op, recovering. You know, you
  308. 8:37can't just go run right after. No, you
  309. 8:39have to rest, recover. You have to do
  310. 8:40like the hyperbaric, the red light, all
  311. 8:42the things, but this is a tool. And so,
  312. 8:44the combination of something called BPC
  313. 8:46157, TB4, or sometimes the synthetic is
  314. 8:49TB5, thymosin beta 4, that's also
  315. 8:52another healing peptide. It helps with
  316. 8:54kind of the way that wounds close.
  317. 8:57>> Mhm.
  318. 8:57>> And then GHK-Cu, which I know you're
  319. 8:59familiar with GHK-Cu.
  320. 9:00>> Exactly, the copper peptide, which is
  321. 9:02very well studied in skin. You use it in
  322. 9:04your multi-peptide serum.
  323. 9:05>> I use copper I love copper peptides.
  324. 9:08>> I've used it. I bought it. I was like, I
  325. 9:09got to try this one.
  326. 9:10>> The peptide serum I put on.
  327. 9:11>> So, but what what GHK-Cu does, which is
  328. 9:13amazing, it has it has antioxidant
  329. 9:15properties. It helps kind of
  330. 9:17potentially, I have to say potentially,
  331. 9:19help the way that scars form to be
  332. 9:21flatter for my patients who are post-op,
  333. 9:23who don't have a cancer history. I say
  334. 9:26we can use this as an adjunct tool.
  335. 9:28>> Mhm.
  336. 9:29>> And what sets the way I do it apart is
  337. 9:32that we will do labs. We make sure you
  338. 9:34don't have a cancer history. In some
  339. 9:35patients, I'll do even a blood test to
  340. 9:37make sure they don't have any cancer
  341. 9:38cells growing. And we'll even do vitamin
  342. 9:41levels because if you're on the glow
  343. 9:42stack, it has copper. Copper impacts
  344. 9:44zinc. And so we need to make sure your
  345. 9:45zinc levels are okay so that we don't
  346. 9:47deplete them further or we can make sure
  347. 9:49to supplement well. And then we we put
  348. 9:52you on them for a short precise period
  349. 9:54of time.
  350. 9:55>> Right.
  351. 9:55>> It's not like you're indefinitely on
  352. 9:57indefinitely on this peptide. You're on
  353. 9:58it for a short precise amount of time
  354. 10:01with a target in mind. Post-op healing.
  355. 10:04>> What I see on Instagram is people on
  356. 10:06GHK-Cu every single day just because for
  357. 10:08fun, and I'm like, "Mm, there's a cutoff
  358. 10:09day here." Like you are not going to be
  359. 10:10on this forever.
  360. 10:11>> Well, you know, the and the other thing,
  361. 10:12you know, I've actually had somebody
  362. 10:14give me um GHK-Cu like a couple years
  363. 10:18ago just on its own, and I I took it for
  364. 10:20like two, three days, and I was like,
  365. 10:22"This burns."
  366. 10:23>> Burns so bad, right?
  367. 10:24>> Yeah, it like on its own, and I actually
  368. 10:25when you had mentioned the glow stack
  369. 10:26and I looked at the peptides, that was
  370. 10:28the first thing I said. I was like, "Is
  371. 10:29this going to hurt?" Cuz I stopped
  372. 10:30taking it because I didn't like it. But
  373. 10:33what I like about your process is you're
  374. 10:34combining the peptides or like you're
  375. 10:36you're suggesting like a stack so that
  376. 10:38they're actually working to complement
  377. 10:40each other and actually give you some
  378. 10:41sort of benefit or potentially give you
  379. 10:42that benefit that you're looking for.
  380. 10:44Whereas like what I am finding with a
  381. 10:46lot of these people who don't really
  382. 10:47understand the mechanisms behind these
  383. 10:50peptides, they're just saying like,
  384. 10:51"This one gives you a glow. It helps
  385. 10:52your skin. This one does this." And so
  386. 10:54you might just be getting piecemeal.
  387. 10:55Like it's like, "Yeah, they're just
  388. 10:56giving you a peptide to start
  389. 10:58injecting."
  390. 10:58>> And the really important part here is
  391. 11:01sourcing.
  392. 11:01>> Mhm.
  393. 11:02>> Where are the peptides being sourced
  394. 11:03from?
  395. 11:04>> Right.
  396. 11:04>> So
  397. 11:06it's a legal gray area, and it's always
  398. 11:08a challenge, but I think things are
  399. 11:10going to change. What I hear down the
  400. 11:11rumor mill is that a lot of the peptides
  401. 11:13are on something called a category two
  402. 11:15do not compound list.
  403. 11:16>> Okay.
  404. 11:16>> There are certain states that have
  405. 11:17exemptions and are able to produce it.
  406. 11:19>> Mhm.
  407. 11:20>> Okay? And so these do not compound
  408. 11:22lists, basically it means that
  409. 11:24compounding pharmacies can't make it.
  410. 11:25>> Right.
  411. 11:26>> So if a compounding pharmacy can't make
  412. 11:27it, then you're going to get get it from
  413. 11:29a gray market, right? Or some research
  414. 11:31place. I am very meticulous about
  415. 11:33sourcing and I think as a consumer you
  416. 11:35need to be aware and say, "Hey, where
  417. 11:37are you getting this peptide from?" You
  418. 11:38can still source it from a 503A
  419. 11:40pharmacy.
  420. 11:41>> Okay.
  421. 11:41>> There are stipulations and things, but
  422. 11:43why do I say get it from an a 503A
  423. 11:45pharmacy versus research-based pharmacy
  424. 11:48or research grade pharmacies? Because
  425. 11:50these 503A pharmacies are being
  426. 11:52inspected.
  427. 11:53>> Mhm.
  428. 11:54>> They are They have to send them out and
  429. 11:56you can ask like is there third-party
  430. 11:57testing? Do you have certificates of
  431. 12:00authenticity? And I have people like on
  432. 12:02Instagram and they're like, "Oh, I I
  433. 12:03have a certificate of authenticity from
  434. 12:05this research pharmacy." And I'm like,
  435. 12:06"But how do you know they didn't make it
  436. 12:07on Canva?"
  437. 12:08>> Right.
  438. 12:09>> Like how do you know it's legit?
  439. 12:10>> Yeah.
  440. 12:10>> How do you know the testing is there?
  441. 12:11And I just think it's really risky and
  442. 12:14really gray. So for example, this
  443. 12:15morning I got an email
  444. 12:16>> Yeah.
  445. 12:17>> from a pharmacy
  446. 12:17>> Okay.
  447. 12:18>> selling me peptides for like basically
  448. 12:20something that costs normally like $500
  449. 12:23for $45.
  450. 12:25>> Interesting.
  451. 12:25>> like, "Wow, I mean this is insane. Like
  452. 12:27what a what a what a price. Like
  453. 12:29>> You're like, "This is like Groupon."
  454. 12:31>> like, "What I'm like this can't be
  455. 12:32real." I literally was like, "This can't
  456. 12:33be real."
  457. 12:34So I sent it to my uncle who's a
  458. 12:36compound pharmacist and I'm like, "Is
  459. 12:38this legit?" And he's like He's very
  460. 12:41involved with legislation in the
  461. 12:43pharmacy world and he's a compound
  462. 12:44pharmacist himself. So he takes his job
  463. 12:46very seriously, very responsibly.
  464. 12:47>> Mhm.
  465. 12:48>> He takes pride in creating medications
  466. 12:51for people who need them.
  467. 12:52>> Right.
  468. 12:53>> So when he sees pharmacies doing this
  469. 12:54he's like, "No, these are crazy
  470. 12:56pharmacies that are popping up taking
  471. 12:57advantage of this desire for peptides
  472. 13:01>> Yeah.
  473. 13:01>> and monopolizing. And then they'll
  474. 13:02disappear then they'll get a slap on the
  475. 13:04wrist. They'll make their money and
  476. 13:05they'll run.
  477. 13:06>> Right.
  478. 13:07>> You want a
  479. 13:08an established long-standing farm
  480. 13:10pharmacy and as a provider I use a 503A
  481. 13:12pharmacy and I I know that it might be
  482. 13:15like something that people desperately
  483. 13:16feel that a peptide is going to make
  484. 13:17them feel better.
  485. 13:19And there are some that are clinically
  486. 13:20studied and FDA approved and that I can
  487. 13:22use more flexibly.
  488. 13:23>> Right.
  489. 13:24>> And I can touch on those in just a
  490. 13:25minute.
  491. 13:25>> Yeah, we will. Yeah.
  492. 13:26>> But it's not worth your health to risk
  493. 13:28it on our research-grade peptide. It's
  494. 13:30just not.
  495. 13:30>> Yeah, I know. And And by the way, do as
  496. 13:33I say, not as I do, cuz sometimes I am
  497. 13:34willing to be like a like a guinea pig
  498. 13:36and stuff. And you know, like I I think
  499. 13:38something that people also don't
  500. 13:39consider is, you know, when I started
  501. 13:41working with you, you started giving me
  502. 13:42these itty-bitty
  503. 13:44needles.
  504. 13:45>> Yeah.
  505. 13:45>> my injections, right? That I mean, I
  506. 13:47didn't get massive needles from the last
  507. 13:49person that was giving me just like
  508. 13:50these one-off peptides, you know? But,
  509. 13:52they weren't the little bitty ones that
  510. 13:54you were giving me. Like they were a
  511. 13:55little bit bigger. They're like, you
  512. 13:56know, just like you're so thoughtful
  513. 13:58about every
  514. 13:59>> Yeah.
  515. 13:59>> step of the process of any kind of
  516. 14:01injectable that I I think people don't
  517. 14:03consider that part, either. It's like,
  518. 14:05you know, that you're They're just
  519. 14:07getting whatever they can get.
  520. 14:08>> Right. And I
  521. 14:08>> Whereas, you're very specific about what
  522. 14:10you want to give your patient.
  523. 14:11>> I am. I'm very meticulous. I'm I'm a
  524. 14:13little upset. I always say like, I know
  525. 14:14I'm a little control freak. I know I'm a
  526. 14:15little cuckoo about this, but it's
  527. 14:17because I always say like,
  528. 14:19safety, patient safety, your safety is
  529. 14:20my priority.
  530. 14:21>> Yeah.
  531. 14:22>> And it should be whenever we're doing
  532. 14:23something that's not traditionally the
  533. 14:25standard of care, because it's not.
  534. 14:27>> Right.
  535. 14:27>> So, like there's this one peptide. It's
  536. 14:29called Well, there's a few, but like one
  537. 14:30in particular, it's called that TA1,
  538. 14:33thymosin alpha 1. Thymo- Thymosin alpha
  539. 14:351, or TA1. I TA1, TA1. We're just going
  540. 14:38to call it TA1. So, there's TA1. And in
  541. 14:39other countries, it's approved, and they
  542. 14:41use it as an adjunct for like hepatitis,
  543. 14:43for cancer. But, here it's not approved.
  544. 14:45So, like if you have a patient that's
  545. 14:47struggling with like immunity, this is
  546. 14:49potentially a tool that you could bring
  547. 14:50up to that that I could bring up to
  548. 14:51them, and I can say, "Hey, look, you
  549. 14:52keep getting sick. Your or your immune
  550. 14:54system's garbage. Really, like we need
  551. 14:56to bolster this immune system. Let Do
  552. 14:58you want to try this?"
  553. 14:59>> Yeah.
  554. 14:59>> That's been used in Europe, in other
  555. 15:01countries, is approved. Obviously, I
  556. 15:03talk about all of this with my patients.
  557. 15:05But, that's a little bit more more of a
  558. 15:07reasonable option, too, because that's
  559. 15:09got human studies. Another FDA-approved
  560. 15:10peptide that I think is amazing that I'm
  561. 15:12actually on right now.
  562. 15:13>> You know I'm always on something when
  563. 15:14I'm here.
  564. 15:14>> I'm like, "I'm trying this one now." Um
  565. 15:16it's called SS-31.
  566. 15:17>> Okay.
  567. 15:17>> Elamipretide. Elamipretide, SS-31.
  568. 15:20>> Okay.
  569. 15:20>> It's actually FDA-approved
  570. 15:22>> Okay.
  571. 15:22>> for something called Barth syndrome.
  572. 15:24>> Okay.
  573. 15:24>> So that's a condition where young boys,
  574. 15:27it's a genetic condition in males, they
  575. 15:28don't have energy in their cells,
  576. 15:29basically. And this was actually studied
  577. 15:31and approved in
  578. 15:33these young males for energy to their
  579. 15:36cells because it allowed them to walk
  580. 15:37further and to do more. And this is a
  581. 15:40fatal condition.
  582. 15:40>> Okay.
  583. 15:41>> So granted, I don't use it for patients
  584. 15:43with Barth, but I use it for people who
  585. 15:45are struggling with long COVID for
  586. 15:46fatigue. You know, like if if somebody's
  587. 15:49got a lot of fatigue, that is a tool
  588. 15:51that I can say, "Hey, your iron's good.
  589. 15:53You're eating great. You're sleeping 7
  590. 15:54hours, but you still feel like you're
  591. 15:56dragging booty? Like let's try SS-31."
  592. 15:58And if they are open to trying it, then
  593. 16:00we'll try it. So that's one that's FDA
  594. 16:01approved.
  595. 16:02>> Yeah. Well, you know what I love is that
  596. 16:03you're never even with me, you're never
  597. 16:05saying like this is for sure going to do
  598. 16:07something. You're really just giving
  599. 16:08like these are alternative options.
  600. 16:10>> Mhm.
  601. 16:11>> The you know, like like you just said,
  602. 16:13you know, it's not like there's that
  603. 16:14many studies on this or like we've only
  604. 16:16got animal studies or we've got these,
  605. 16:17you know, in vitro studies and stuff,
  606. 16:19but like here's something we can try.
  607. 16:21And I think that's like the key here is
  608. 16:23you don't want to go to somebody who's
  609. 16:25going to be like, "No, this is for sure
  610. 16:26going to do something for you." Right?
  611. 16:27>> Yeah. Yeah, because how do I mean,
  612. 16:29listen, I I don't even know for sure
  613. 16:32that an antibiotic is going to for sure
  614. 16:34knock out your UTI unless I get a
  615. 16:35culture and a sensitivity back and then
  616. 16:37I know for sure that that antibiotic
  617. 16:39will work. I think in medicine we have
  618. 16:41to say there's a science and there's an
  619. 16:43art and there's the unique person,
  620. 16:45right? Peptides are a tool in the the
  621. 16:48landscape of your health.
  622. 16:50>> Right.
  623. 16:50>> But they're not the only tool.
  624. 16:52>> And our health is dynamic, right? Like
  625. 16:53it's always constantly changing.
  626. 16:54Sometimes something does fix or like
  627. 16:56temporarily fix something or helps you
  628. 16:58through I guess like an issue you're
  629. 17:00dealing with, but then you start to
  630. 17:02experience something else or like it
  631. 17:03needs to change or like you said, you
  632. 17:04don't indefinitely stay on these
  633. 17:06injectable peptides, right? Let's talk
  634. 17:07about some of the I guess popular
  635. 17:10peptides starting probably with like the
  636. 17:11GLP-1s because people don't realize that
  637. 17:14these are a form of injectable peptides
  638. 17:16that are actually approved and widely
  639. 17:17used right now.
  640. 17:18>> Yeah. Yeah, and GLP-1s were first
  641. 17:19approved for diabetes. They were not
  642. 17:21approved for weight loss.
  643. 17:23>> Mhm.
  644. 17:24>> And that's an off-label use. Yeah, and
  645. 17:25they started being used off-label for
  646. 17:27weight loss.
  647. 17:27>> Mhm.
  648. 17:28>> Which is probably the most popular way
  649. 17:29it's being used at this time.
  650. 17:30>> amazing though. I mean, I think if you
  651. 17:34use a GLP-1
  652. 17:36correctly,
  653. 17:36>> Mhm.
  654. 17:37>> it's my favorite tool in my toolbox
  655. 17:39because we have so much safety data.
  656. 17:41>> Mhm.
  657. 17:41>> I had a patient with chronic pelvic
  658. 17:43pain. She had given birth to two kids
  659. 17:46and she was doing pelvic floor physical
  660. 17:47therapy and she just had this chronic
  661. 17:48pelvic pain. She could not walk.
  662. 17:50>> Mhm.
  663. 17:51>> She was like, "Every time I walk, I'm in
  664. 17:51so much pain."
  665. 17:53We microdosed and I'm talking like 0.25
  666. 17:56mg of a GLP-1.
  667. 17:58>> Mhm.
  668. 17:58>> And I was really I'm like she she was a
  669. 18:01you know, a
  670. 18:02normal girl.
  671. 18:02>> Yeah.
  672. 18:03>> A normal woman, normal body type, but I
  673. 18:05was like, "You're not going to lose
  674. 18:06muscle.
  675. 18:06>> Yeah.
  676. 18:07>> You're going to eat the nutrition that
  677. 18:08you need to eat.
  678. 18:09>> Yep.
  679. 18:09>> We did the protein goals. She put on
  680. 18:11muscle
  681. 18:12and her pain went away.
  682. 18:13>> That's because it has anti-inflammatory
  683. 18:15>> It has anti-inflammatory properties. So,
  684. 18:17it potentially has anti-inflammatory
  685. 18:18properties. A lot of patients will
  686. 18:20report that they feel less puffy, less
  687. 18:22bloated, and there are some diuretic
  688. 18:24properties there too. So, one thing that
  689. 18:27I don't think people realize is when
  690. 18:28you're on a GLP-1, you need to still
  691. 18:30hydrate and you have to push hydration.
  692. 18:32I had an actually really interesting
  693. 18:33thing because GLP-1s work in the brain
  694. 18:35and they work in the gut.
  695. 18:36>> Mhm.
  696. 18:36>> Right? So, they work in the brain to
  697. 18:37kind of say, "Hey, impulses of hunger or
  698. 18:40or, you know, emotional eating and these
  699. 18:42type of things slow down." And they work
  700. 18:44in the gut to slow down digestion and
  701. 18:45they potentially tell your body, "Hey,
  702. 18:46we need to produce insulin or we don't."
  703. 18:48So, they work in that way. But, it can
  704. 18:50actually have like a counter effect,
  705. 18:52right? So, if you're a person who really
  706. 18:53really loves eating and the joy of food,
  707. 18:56I had one patient who was like, "I don't
  708. 18:57want to be on a GLP-1 anymore." And we
  709. 18:58were on a microdose and she was like, "I
  710. 19:00don't want to be on a GLP-1 anymore. It
  711. 19:01made me sad."
  712. 19:02>> Oh, we don't
  713. 19:04>> Yeah.
  714. 19:04>> And I was like, "Get off that
  715. 19:05immediately. We will find another way to
  716. 19:07manage inflammation." Because she was
  717. 19:09like, "I just don't feel like that
  718. 19:10excitement that I would get when I would
  719. 19:12go out to eat and and I'm talking like
  720. 19:13we were on a baby dose.
  721. 19:14>> Yeah.
  722. 19:15>> But
  723. 19:15>> I'm like if that's like part of being
  724. 19:17alive too and like we chase longevity
  725. 19:19and we want health span and lifespan but
  726. 19:21like we need to live.
  727. 19:22>> Yeah.
  728. 19:23>> And if food brings joy, we have to
  729. 19:25>> Yeah, for sure. Well, you know what's
  730. 19:26interesting? So so throwing out there
  731. 19:28also that you got me on tirzepatide but
  732. 19:31microdosing but the conversation we had
  733. 19:33and I think that people had these
  734. 19:34experiences, right? I had said that one
  735. 19:36time for like a month a while back I had
  736. 19:39like a friend who's a nurse practitioner
  737. 19:41give me a semaglutide it was probably
  738. 19:42like old school Ozempic.
  739. 19:44>> Yeah.
  740. 19:44>> And I felt she gave me too much. I felt
  741. 19:47super sick on it. I hated it. I was like
  742. 19:49I'm never going to do this again. And
  743. 19:50then you're like, but first off
  744. 19:52tirzepatide.
  745. 19:53>> Yes.
  746. 19:54>> [laughter]
  747. 19:54>> And you were like and microdosing it cuz
  748. 19:56I was like I don't want to necessarily
  749. 19:57lose weight. I don't want to lose
  750. 19:58muscle. I don't want to feel like again
  751. 20:01cuz I also enjoy food and eating and
  752. 20:02stuff and just also like feeding my body
  753. 20:04after working out and everything. And I
  754. 20:06had said that like when I was on the on
  755. 20:08the Ozempic it just made me feel like I
  756. 20:10didn't have energy. I felt nauseous. It
  757. 20:13almost felt like I was pregnant. Like
  758. 20:15that first trimester of pregnancy where
  759. 20:16you're just nauseous and sick and even
  760. 20:18though you're supposed to be eating
  761. 20:19protein I was eating bread.
  762. 20:20>> Yeah, yeah.
  763. 20:21>> What's happening here? Yeah.
  764. 20:23>> And so I was like that I was like
  765. 20:24worried about that happening if I ever
  766. 20:25microdosed
  767. 20:27any other kind of GLP-1 and then you you
  768. 20:29were like just try it for your
  769. 20:31inflammation.
  770. 20:31>> Yeah.
  771. 20:32>> I think it's a really common thing that
  772. 20:34I actually see is patients that have a
  773. 20:35little PTSD from being started on too
  774. 20:38high of a dose. So
  775. 20:39the FDA starting dose of semaglutide is
  776. 20:410.25 for semaglutide and 2.5 mg for
  777. 20:44tirzepatide. I will start my patients
  778. 20:46significantly lower that than that
  779. 20:48sometimes at 0.5 mg for tirzepatide.
  780. 20:52I'm not telling you this to experiment
  781. 20:53on yourself.
  782. 20:53>> No.
  783. 20:54>> 0.5 mg of tirzepatide to 1 mg and then I
  784. 20:57would rather them say to me, I don't
  785. 20:59really feel anything.
  786. 21:00>> Yeah.
  787. 21:00>> But I'll monitor their body composition.
  788. 21:02>> Yeah.
  789. 21:03>> And I personally microdose a GLP-1.
  790. 21:05>> Yeah.
  791. 21:05>> I found for my undiagnosed autoimmune
  792. 21:08whatever I have going on, it helps me so
  793. 21:09much with my joint pain.
  794. 21:10>> Yeah.
  795. 21:11>> And I will say that I think people have
  796. 21:14to be careful because growing up when at
  797. 21:16a time when skinny was in,
  798. 21:18>> Mhm.
  799. 21:19>> like
  800. 21:20stick skinny was like the only way to be
  801. 21:22and having a big booty girl is sorry.
  802. 21:23>> we should be honest and like admit that
  803. 21:25like with especially with the uprise of
  804. 21:27like GLP-1s, yeah.
  805. 21:28>> Yeah.
  806. 21:29>> Everybody actually, no matter what with
  807. 21:31body positivity and everything, we can
  808. 21:33see how people just immediately fall
  809. 21:35right back into I just want to be a
  810. 21:37skinny
  811. 21:37>> Right. And I think like so so definitely
  812. 21:39like you got to worry about people's
  813. 21:40mentality and like the psychology behind
  814. 21:42it and not and make sure that they're
  815. 21:43not going to go off the deep end.
  816. 21:45>> And I'm I'm vigilant of that because I
  817. 21:48want and what I tell everybody is I get
  818. 21:50it, skinny is kind of trending again.
  819. 21:52>> Mhm.
  820. 21:52>> But I don't want you to be skinny.
  821. 21:53>> Yeah.
  822. 21:54>> Because what happens when a big booty's
  823. 21:55back in again?
  824. 21:56>> Yeah.
  825. 21:57>> It will come back. Everything comes
  826. 21:58back.
  827. 21:58>> never go out of style.
  828. 21:59>> right? Like so
  829. 21:59>> Like the massive ones, fine, out of
  830. 22:01style. But like a healthy juicy butt
  831. 22:03>> Yeah, like we love the booty, right? So
  832. 22:05I'm like, I want you to be a strong old
  833. 22:07lady. Like I want you to be 80 80 90 100
  834. 22:11and be super strong. Yeah, like guns,
  835. 22:14you know, booty, like feel like you're
  836. 22:16not falling off of a toilet seat. And so
  837. 22:18we can still do that with GLP-1s.
  838. 22:20>> And I love that you pointed out that
  839. 22:21like you want people to almost be like
  840. 22:23it's not like I don't feel anything.
  841. 22:25I'll throw out there like with the
  842. 22:26tirzepatide, felt nothing cuz it's such
  843. 22:27a small dose and I think like you told
  844. 22:29me to do it like weekly, but I think
  845. 22:30like at this point cuz I travel so much
  846. 22:32and stuff, I don't want to take it with
  847. 22:33me. So I'll do it like every 2 weeks or
  848. 22:35something like that. And it's like the
  849. 22:35smallest amount. It's so such a small
  850. 22:37amount that even when I I I like think
  851. 22:39about this every time I put the the
  852. 22:40needle into like pull a little bit out,
  853. 22:42it's like boop. It's like a little like
  854. 22:43boop.
  855. 22:44And then boop, like it just feels like a
  856. 22:46like it's just very little, but I do
  857. 22:48overall feel better. Like actually, this
  858. 22:50is really the only thing I'm doing right
  859. 22:51now. I had been on the Glow Stack and
  860. 22:53we'll talk about that next. And then you
  861. 22:54got me on the microdosing of tirzepatide
  862. 22:56and I have to say like people are always
  863. 22:58like, what's your immune system? Like
  864. 22:59what are you you're for your immune
  865. 23:00system that you're traveling so much to
  866. 23:02all these different countries, all these
  867. 23:04different time zones, and then you get
  868. 23:06back and you're like not sick. And
  869. 23:08honestly, I just think it's the
  870. 23:09tirzepatide.
  871. 23:09>> I think it helps with the immune system,
  872. 23:11too. I mean, there's anti-cancer studies
  873. 23:13on it. Like, there's a lot of benefits
  874. 23:15to GLP-1s. And so, I think it's just in
  875. 23:18the way that you use it. And
  876. 23:20truly, muscle is the organ of longevity.
  877. 23:22>> Yep.
  878. 23:22>> Like, I
  879. 23:23>> 100%.
  880. 23:24>> So, we don't want to lose that. So, we
  881. 23:26have to work really intentionally. And
  882. 23:27I'm not going to lie, like, with your
  883. 23:28travel schedule, sometimes I think, "Oh
  884. 23:29my god, I want to put Susan on this."
  885. 23:30Or, "I want to put her on that."
  886. 23:31>> Yeah.
  887. 23:31>> And
  888. 23:32And like, I have so many ideas. But, you
  889. 23:33don't need it.
  890. 23:34>> Yeah.
  891. 23:34>> So, if you don't need it,
  892. 23:35>> Yeah.
  893. 23:36>> it's a tool.
  894. 23:36>> And you know that I'm going to come to
  895. 23:37you with questions. I'm going to be
  896. 23:38like, "Hey, I'm feeling this way." But,
  897. 23:40like, lately, I mean, a year of working
  898. 23:42with Mimi, you guys, I feel amazing. I
  899. 23:43want to talk about some of the most
  900. 23:44popular peptides. Um, the glow stack is
  901. 23:47probably one of them. But, you actually
  902. 23:48you keep mentioning NAD. And I And I do
  903. 23:50want to talk about that really quickly,
  904. 23:52just touch on it. Because NAD, I think,
  905. 23:54is one of those injectables that like
  906. 23:55got really popular fast. Um, and I
  907. 23:58remember talking to you about it. And
  908. 24:00you weren't anti-NAD. You're like,
  909. 24:02"Let's try it." But, you also were had
  910. 24:03it like an opinion about it because the
  911. 24:05information about it's constantly
  912. 24:06changing. So, let's talk about it.
  913. 24:07>> I still have an opinion about NAD. So,
  914. 24:09NAD is not a peptide. It's a coenzyme,
  915. 24:11right? And we make NAD in our bodies.
  916. 24:14And as we age, it declines. Right. NAD
  917. 24:16is great. But, what people don't realize
  918. 24:18is that you need other vitamins to
  919. 24:21support the production of NAD.
  920. 24:22>> Right.
  921. 24:23>> You need B12. You need folate. There's
  922. 24:25like a whole I could show you the
  923. 24:27videos. There's like a whole organic
  924. 24:28chemistry course that we have to take
  925. 24:30>> Okay.
  926. 24:30>> potentially. Like, there's a lot that
  927. 24:32goes beyond just NAD. And we need a lot
  928. 24:34in order to produce NAD.
  929. 24:35>> Mhm.
  930. 24:36>> So, people are pushing doing NAD, NAD,
  931. 24:37NAD. But, the problem is that there's no
  932. 24:39nuance behind it. That they're just
  933. 24:41giving NAD. And they're not looking at
  934. 24:43the person's health picture.
  935. 24:45>> Mhm.
  936. 24:45>> So, if you don't like, potentially give
  937. 24:48NAD with B12 or folate or something
  938. 24:50called betaine, then it could
  939. 24:52potentially cause an increase in
  940. 24:54something called homocysteine. And then,
  941. 24:56that increase in homocysteine is related
  942. 24:58to not causes but related to negative
  943. 25:01cardiac outcomes.
  944. 25:02>> Okay.
  945. 25:03>> So we need to be careful. And people
  946. 25:04will say, "Oh my gosh, I got this NAD
  947. 25:05infusion. I felt so sick. It must be
  948. 25:08working."
  949. 25:09>> It must be working. It must be working.
  950. 25:11>> And I'm like, "Well,
  951. 25:13>> Yeah.
  952. 25:13>> actually what happened was that the NAD
  953. 25:16can sometimes have a a vasodilatory
  954. 25:18effect, meaning it opens up your blood
  955. 25:19vessels. And so your heart rate
  956. 25:21increases and your blood pressure drops
  957. 25:23and you feel like garbage.
  958. 25:24>> Yeah.
  959. 25:24>> There are places and cases and I know
  960. 25:26clinicians who use NAD for long COVID
  961. 25:28patients, for Parkinson's patients and
  962. 25:30they use it for a lot of people. And I
  963. 25:32will still use NAD. Like if I have a
  964. 25:34cocktail, which I really do but if I do,
  965. 25:36the day after, I'll do an NAD shot
  966. 25:38because alcohol can deplete your NAD
  967. 25:40levels.
  968. 25:40>> Right.
  969. 25:41>> So I'm more like, let's intentionally
  970. 25:43use this NAD.
  971. 25:44>> What is the difference between injecting
  972. 25:46it with just like a needle? The
  973. 25:48infusions, like the IV infusions cuz I I
  974. 25:50hear people say all this all the time
  975. 25:51that they're doing an IV infusion of it
  976. 25:53this week or something and I'm like, how
  977. 25:55is that going to help them if they're
  978. 25:56not doing it like on a daily or weekly
  979. 25:58basis with injectables, right? With the
  980. 26:00injection. And then there's also
  981. 26:01obviously the supplements, right? That
  982. 26:03you can actually just orally take. Is
  983. 26:05there a difference or do we not know?
  984. 26:07>> So there is a difference. It also
  985. 26:08depends on the peptide. Okay, so let's
  986. 26:10start with NAD.
  987. 26:11>> Mhm.
  988. 26:12>> NAD itself as an oral molecule is too
  989. 26:14big and your digestive enzymes will
  990. 26:16break it down.
  991. 26:17>> Okay.
  992. 26:18>> So NAD itself orally
  993. 26:21trash. Right, trash. NMN and NR, these
  994. 26:24are precursors to NAD and your body
  995. 26:26converts them. And they're actually very
  996. 26:28very well studied in humans, NMN and NR.
  997. 26:31And so those orally
  998. 26:33>> But probably with a whole stack of other
  999. 26:36nutrients and vitamins to
  1000. 26:36>> probably want to do like something with
  1001. 26:38betaine, B12, folate but also you want
  1002. 26:41to check your labs because how's your
  1003. 26:43B12? How's your folate? Like, you know?
  1004. 26:45So that's NAD. And then if you do an
  1005. 26:47injection, it's not so aggressive. So
  1006. 26:49anytime you you something through an IV,
  1007. 26:51it's going to feel more potent, right?
  1008. 26:53It's going straight into the vein. When
  1009. 26:55you do an injection into your
  1010. 26:56subcutaneous fat, you're almost creating
  1011. 26:58like a little bleb in the fat that
  1012. 27:01slowly disperses over time.
  1013. 27:03>> Okay.
  1014. 27:04>> I'm a slow and steady kind of girl.
  1015. 27:05Yeah. The turtle won the race anyways,
  1016. 27:07you know, we're going to get there. So,
  1017. 27:08let's get there with tranquility
  1018. 27:11and not palpitations, you
  1019. 27:12>> Right. Right. Right.
  1020. 27:13>> Then BPC 157, that one's made in the
  1021. 27:15gut. Right. So, that's a really cool
  1022. 27:17peptide because that one orally you can
  1023. 27:19take it and the digestive juices don't
  1024. 27:21really break it down.
  1025. 27:22>> Okay.
  1026. 27:23>> That's a really interesting peptide that
  1027. 27:25potentially could be used in patients
  1028. 27:27with like H. pylori, celiacs, uh like
  1029. 27:30stomach issues
  1030. 27:31>> Okay.
  1031. 27:31>> because it reduces inflammation. And so,
  1032. 27:33like when you have an inflammatory gut
  1033. 27:34condition, again sourcing matters,
  1034. 27:37that is a potential peptide that could
  1035. 27:38be beneficial that you can take orally.
  1036. 27:40Okay. But, if you are dealing with like
  1037. 27:42a torn ligament or a knee injury, then
  1038. 27:45we're going to inject that peptide. And
  1039. 27:47there are even some practitioners
  1040. 27:48>> Like locally, like where it's hurting
  1041. 27:49at?
  1042. 27:50>> like, you know, I have a best friend and
  1043. 27:52she pulled her knee. She was like a
  1044. 27:53nothing and she pulled her knee and we
  1045. 27:54did a round of BPC on her knee
  1046. 27:56and she felt better. She didn't have to
  1047. 27:58get surgery. I mean, maybe she will need
  1048. 28:00to eventually, but it did delay it. Now,
  1049. 28:03the question always comes up, is this
  1050. 28:04placebo or is this real life? To which I
  1051. 28:05say, if it works, who cares?
  1052. 28:08>> Right.
  1053. 28:09>> Like truly, you feel better. The mind is
  1054. 28:11powerful. If you this tool allowed your
  1055. 28:13mind to help you heal, then I think
  1056. 28:14that's still a win. But, I guess it
  1057. 28:16depends.
  1058. 28:16>> Yeah.
  1059. 28:17>> Then there's other peptides that so it
  1060. 28:19that you can't do orally because they'll
  1061. 28:21break down.
  1062. 28:21>> Okay. So, it really is kind of dependent
  1063. 28:23on each of these peptides or coenzymes
  1064. 28:25or everything.
  1065. 28:26>> Yeah. And NAD itself is just a really
  1066. 28:28big molecule. There's even the theory of
  1067. 28:30like it's so big, even if you inject
  1068. 28:32NAD, does it really raise your plasma
  1069. 28:34levels of NAD? And that's a question
  1070. 28:36mark. But, there's now a conversation
  1071. 28:38around something called CD38 and CD38
  1072. 28:42actually degrades or breaks down your
  1073. 28:44NAD. So, if If can come up with
  1074. 28:45something that says to CD38, "Hey, stop
  1075. 28:48breaking down NAD." then we can
  1076. 28:49naturally boost NAD levels.
  1077. 28:51>> Mhm.
  1078. 28:52>> another cool tool. We just don't have
  1079. 28:53that yet.
  1080. 28:53>> Yeah. You know, you bring up another
  1081. 28:55point of like why it's important to work
  1082. 28:57with a real practitioner like you, like
  1083. 28:59a medical practitioner, while you're
  1084. 29:00doing any of these types of injectables
  1085. 29:02and it's because the the information is
  1086. 29:04constantly changing, especially as it
  1087. 29:05becomes more popular. Like you saying
  1088. 29:07that now there's a study happening in
  1089. 29:08China with these peptides and stuff.
  1090. 29:10It's like it's obviously becoming more
  1091. 29:11popular. There might be more studies
  1092. 29:13that come out. More information will
  1093. 29:14absolutely come out, whether it's good
  1094. 29:16or bad information, as everything
  1095. 29:18changes and it's it's really important
  1096. 29:20to have someone like you to keep your
  1097. 29:22patients informed about stuff that
  1098. 29:24they're taking, right?
  1099. 29:25>> Yeah.
  1100. 29:26>> So.
  1101. 29:26>> Oh, and now you just made me remember
  1102. 29:27TB4. There's actually a study um in dry
  1103. 29:30eyes, so eye drops that you can
  1104. 29:32potentially use for dry eyes and that's
  1105. 29:33a phase two, phase three trial in dry
  1106. 29:35eyes as we get older, like I don't know,
  1107. 29:36I have dry eyes all the time and I wear
  1108. 29:38contacts. So, I this is a very promising
  1109. 29:41interesting use of TB4. That's why it's
  1110. 29:43like it's not that it's
  1111. 29:46dangerous or crazy or experimental. It's
  1112. 29:48a little bit of both, depending on how
  1113. 29:49you use it.
  1114. 29:50>> [laughter]
  1115. 29:51>> Right. It depends on how it's used, you
  1116. 29:53know?
  1117. 29:53>> Right. Right.
  1118. 29:54>> So, I don't know. It's
  1119. 29:55>> So, going to a medical professional is
  1120. 29:56probably key number one.
  1121. 29:58>> Yes, I think going to a medical
  1122. 29:59professional is important.
  1123. 30:01>> Let's touch on uh the glow stack has
  1124. 30:02three different peptides and I feel like
  1125. 30:04I see a lot of people on them. I did
  1126. 30:06mine for like two and a half, three
  1127. 30:07months almost and this was post surgery.
  1128. 30:09So, this is what you suggested post
  1129. 30:10surgery.
  1130. 30:11Let's tell everybody what these these
  1131. 30:13peptides do.
  1132. 30:13>> So, the glow stack is a combination of
  1133. 30:15three peptides, BPC 157, TB4, and
  1134. 30:19GHK-Cu. The pharmacy that I use that
  1135. 30:21makes it actually tests that the
  1136. 30:23potency, meaning that they all still
  1137. 30:25work when they're combined. Because
  1138. 30:26sometimes when you combine these
  1139. 30:27peptides, they actually don't work.
  1140. 30:29>> Right.
  1141. 30:29>> They inactivate each other because they
  1142. 30:31require different pHs. So, it's
  1143. 30:32important to know that if they're
  1144. 30:34combined, were they tested for potency?
  1145. 30:36>> Yeah.
  1146. 30:36>> And they were.
  1147. 30:37>> Right.
  1148. 30:38>> And actually I'll point out in skin care
  1149. 30:40for Naturium, when we use our copper
  1150. 30:41peptides we encapsulated the copper
  1151. 30:43peptides because copper peptides since
  1152. 30:45they act like antioxidants can actually
  1153. 30:47be very unstable. So that's a good point
  1154. 30:49to bring up to people.
  1155. 30:50>> Yeah.
  1156. 30:50>> And the studies on GHK-Cu topical in a
  1157. 30:52nano lipid carrier are how they
  1158. 30:55penetrate the skin. So when I saw that
  1159. 30:57Naturium had it made that way of course
  1160. 30:59I bought it.
  1161. 31:00>> So that glow stack is really great for
  1162. 31:02>> It's great for I like to use it post-op
  1163. 31:04or post injury.
  1164. 31:06>> Mhm.
  1165. 31:06>> Because for example if you have a breast
  1166. 31:08implant I used it for my I had an
  1167. 31:11explant done and I did it for my breast
  1168. 31:13explant and my surgeon was like your
  1169. 31:14scars healed so well. Now granted I also
  1170. 31:17did hyperbaric oxygen I did the peptide
  1171. 31:20and I did my very nutritious high
  1172. 31:23protein diet right?
  1173. 31:24>> Right.
  1174. 31:24>> So people who have an injury what it
  1175. 31:26could potentially do is it decreases
  1176. 31:28inflammation.
  1177. 31:29>> Mhm.
  1178. 31:29>> It tells your fibroblasts and basically
  1179. 31:33like collagen and blood vessels to
  1180. 31:36regenerate.
  1181. 31:37>> Mhm.
  1182. 31:37>> So it has does something potentially
  1183. 31:38called angiogenesis which is the growth
  1184. 31:40of new blood vessels and that's where we
  1185. 31:42go could this cause cancer?
  1186. 31:43>> Right.
  1187. 31:44>> have to be careful.
  1188. 31:45And then GHK-Cu oh my gosh it's so cool
  1189. 31:47in theory the mechanism of GHK-Cu it
  1190. 31:50communicates with the cells and it can
  1191. 31:52either upregulate or downregulate cells
  1192. 31:54meaning it can either tell them to
  1193. 31:55behave or not behave in certain ways to
  1194. 31:58your genes. And so it has this really
  1195. 32:00powerful anti-inflammatory antioxidant
  1196. 32:02communication kind of throughout our
  1197. 32:03body. And so we use it or I use it
  1198. 32:07post-op.
  1199. 32:08>> Okay. That
  1200. 32:08>> to support the healing.
  1201. 32:09>> We've also heard about the Wolverine
  1202. 32:11stack on social media. What is this one?
  1203. 32:12>> Okay. Wolverine stack. No it's awesome.
  1204. 32:14Wolverine stack is great and I will use
  1205. 32:16it in patients with like a
  1206. 32:18musculoskeletal or soft tissue injury.
  1207. 32:21It's awesome. Orthopedic surgeons often
  1208. 32:23use it and they actually used it before
  1209. 32:25I used it. Not all orthos use it but
  1210. 32:28some orthos use it. Dr. William Seeds is
  1211. 32:30an orthopedic surgeon turned peptide
  1212. 32:32guru educator and he he even talks about
  1213. 32:35how he used this and he used collagen
  1214. 32:38and different modalities to help heal
  1215. 32:39his patients and he was like I didn't
  1216. 32:40need surgery and so I changed what I was
  1217. 32:42doing. But it's BPC 157 and TB4. They
  1218. 32:45work together with angiogenesis,
  1219. 32:47anti-inflammatory, wound healing
  1220. 32:50and it's a great tool in the toolbox.
  1221. 32:51>> Right.
  1222. 32:52>> And and
  1223. 32:52>> But it it's just removing the
  1224. 32:54>> The GHK-Cu.
  1225. 32:55>> Yes, the no copper peptides
  1226. 32:56>> Yeah, no copper peptides which for me if
  1227. 32:59I have a patient that I haven't been
  1228. 33:01able to do really recent labs on
  1229. 33:03>> Yeah.
  1230. 33:03>> maybe that would be a good choice
  1231. 33:05because we know that I don't need to
  1232. 33:07know what their copper levels look like.
  1233. 33:08>> Right. Right, right, right.
  1234. 33:09>> What do their zinc levels look like? I
  1235. 33:10can put them on this BPC 157, Wolverine
  1236. 33:12stock, TB4. We have very minimal human
  1237. 33:15studies on BPC 157. We have like two or
  1238. 33:18three.
  1239. 33:18>> Right.
  1240. 33:18>> There's one clinical trial going on
  1241. 33:19right now and then TB4 we have a few
  1242. 33:21human studies in other countries too but
  1243. 33:23like we always could use more studies
  1244. 33:25but who's going to who's doing it?
  1245. 33:27>> And it's already making money so it's
  1246. 33:28always that's actually the issue, right?
  1247. 33:30>> That's the issue, yes.
  1248. 33:30>> Tesamorelin?
  1249. 33:31>> Oh, I love tesamorelin. So tesamorelin
  1250. 33:34is
  1251. 33:34>> Tesamorelin?
  1252. 33:36>> Tesamorelin. But I I mean that's the way
  1253. 33:37I say it. Basically communicates with
  1254. 33:41your brain to tell your body to produce
  1255. 33:43more growth hormone.
  1256. 33:44>> Okay.
  1257. 33:44>> And it's actually FDA approved for HIV
  1258. 33:47lipodystrophy. So lipodystrophy means
  1259. 33:50like your fat is not where it should be
  1260. 33:52and particularly in the belly fat
  1261. 33:54visceral organs and so that is a peptide
  1262. 33:56that I will use in my patients
  1263. 33:57off-label.
  1264. 33:58>> Mhm.
  1265. 33:59>> And so people will be like oh these are
  1266. 34:00all not FDA approved but if you only
  1267. 34:02want to do what's FDA approved we can
  1268. 34:04absolutely use FDA approved peptides and
  1269. 34:06your clinician should know the
  1270. 34:07difference of what's FDA approved like
  1271. 34:09tesamorelin which is FDA approved in
  1272. 34:11patients with lipodystrophy who have HIV
  1273. 34:14a very specific population but we can
  1274. 34:15use it off-label in patients who don't
  1275. 34:18have HIV, who have belly fat, who have a
  1276. 34:21low IGF-1, who are having a hard time
  1277. 34:24losing fat and putting on muscle. Now it
  1278. 34:26can cause bloating, it can cause water
  1279. 34:28retention and in some cases it can cause
  1280. 34:30blood sugar to rise and so we look at
  1281. 34:33labs because we need to monitor that.
  1282. 34:34The reason why GHK-Cu is so popular is
  1283. 34:37because it hits so many things.
  1284. 34:39Performance, oh my gosh, it can help
  1285. 34:41with my antioxidant capacity, it's
  1286. 34:43anti-inflammatory, it helps with my
  1287. 34:45skin. And so it has a lot of promise.
  1288. 34:48>> Right.
  1289. 34:48>> But I want to see what the actual proof
  1290. 34:50is and I think we see that over time.
  1291. 34:51CJC, did we talk about that? Oh, we
  1292. 34:52didn't, but CJC is similar to
  1293. 34:54Tesamorelin that it communicates with
  1294. 34:55the brain to produce more growth
  1295. 34:57hormone. Right now it's on the do not
  1296. 34:58compound list. There was and there have
  1297. 35:00been human clinical trials on it. There
  1298. 35:03was one death associated with one of the
  1299. 35:04clinical trials, but it wasn't related
  1300. 35:06to that.
  1301. 35:07>> Okay.
  1302. 35:08>> So but it's it's again potentially for
  1303. 35:10muscle building, but I'm always like,
  1304. 35:12well, we can use the Tesamorelin which
  1305. 35:14is FDA approved and a little bit more
  1306. 35:17>> has more studies on
  1307. 35:17>> more studies.
  1308. 35:18>> Okay. So if somebody's saying CJC, ask
  1309. 35:20more questions.
  1310. 35:21>> Yeah, but it's still a good option.
  1311. 35:22>> It's still a good option.
  1312. 35:23>> yeah, it's still a good option. It's
  1313. 35:24just again harder to source safely. Some
  1314. 35:26pharmacies don't want to produce it
  1315. 35:27because of
  1316. 35:28>> the studies
  1317. 35:29>> the gray area and the legalities, but
  1318. 35:30hopefully things will be changing and
  1319. 35:32rumor has it that peptides will be
  1320. 35:34moving from category two to category
  1321. 35:35one, which means that we'll be able to
  1322. 35:36compound them again. And the reason why
  1323. 35:38that's happening is because
  1324. 35:39>> They're already off-label, gray market.
  1325. 35:42>> Yes, a friend of mine sent me a picture
  1326. 35:43of she lives in California, she was at
  1327. 35:44the gym and they're literally selling
  1328. 35:46vials of peptides at her gym.
  1329. 35:47>> Shut up.
  1330. 35:48>> But she could lose her license if she
  1331. 35:49prescribes them.
  1332. 35:50>> Right. That's ridiculous.
  1333. 35:51>> Tell me
  1334. 35:52>> Make it make sense.
  1335. 35:52>> Make it make sense.
  1336. 35:53>> Make it make sense.
  1337. 35:54>> Make it so that the actual medical
  1338. 35:55practitioners can do it.
  1339. 35:56>> Yeah, safely.
  1340. 35:57>> TA1, did we talk about that?
  1341. 35:58>> Oh, yeah. So Thymosin alpha 1, that's
  1342. 36:00the one that's been studied in other
  1343. 36:01countries that's immunomodulatory. So it
  1344. 36:03can help potentially with immune
  1345. 36:06function and as we age our thymus gland
  1346. 36:09gets smaller and so it can support that.
  1347. 36:11So say that you're traveling a lot and
  1348. 36:12you're getting sick, that would be a
  1349. 36:14good tool that we could put in the
  1350. 36:14toolbox.
  1351. 36:15>> All right.
  1352. 36:16>> It's used it for hepatitis and in other
  1353. 36:18countries it's approved, but it's just
  1354. 36:19not approved here.
  1355. 36:20>> And then as far as longevity goes, how
  1356. 36:22do peptides fit in? Like are all of
  1357. 36:24these peptide these injectable peptides
  1358. 36:25basically for longevity?
  1359. 36:27>> So I think they could be a tool in your
  1360. 36:29toolbox. Are they going to replace a
  1361. 36:31strong diet and exercise?
  1362. 36:34>> No.
  1363. 36:34>> Right. They're a tool. They can support,
  1364. 36:36but not replace
  1365. 36:37>> Mhm.
  1366. 36:38>> the essentials, which are diet and
  1367. 36:40exercise. And I think that they can help
  1368. 36:41in really acute situations like long
  1369. 36:43COVID or Parkinson's or they can add
  1370. 36:46quality of life potentially for somebody
  1371. 36:48who has like a knee injury, but really
  1372. 36:49enjoys playing pickleball.
  1373. 36:51>> Right. And gets relief from it. How
  1374. 36:52about for anti-aging? Like for the
  1375. 36:54actual like skin and look and your hair
  1376. 36:55and everything?
  1377. 36:56>> I would love to say yes, but I I think
  1378. 36:58we need more studies
  1379. 36:59>> Yeah.
  1380. 36:59>> to say that it actively works. We know
  1381. 37:01GHK-Cu topically can improve collagen. I
  1382. 37:04think it there was a study done with
  1383. 37:05GHK-Cu, vitamin C, and tretinoin and
  1384. 37:08GHK-Cu had better outcomes than both
  1385. 37:10vitamin C and tretinoin.
  1386. 37:11>> Oh, that's interesting.
  1387. 37:12>> Yeah. But I don't know if I would get
  1388. 37:14rid of my tret and my vitamin C. I think
  1389. 37:15I might just add it to the mix, right?
  1390. 37:16Cuz it helps boost collagen. But again,
  1391. 37:18I think it's part of a bigger picture,
  1392. 37:20right? You can use the GHK-Cu and maybe
  1393. 37:22if you're open to being a guinea pig and
  1394. 37:23experimenting with yourself safely with
  1395. 37:26the right sourcing, maybe you try a
  1396. 37:27cycle of the GHK or the glow stack
  1397. 37:29cautiously knowing that there are risks
  1398. 37:31and that there's not enough studies and
  1399. 37:33see how you feel with your skin. But do
  1400. 37:36I think it's going to replace Sculptra,
  1401. 37:38laser, and facelifts? No.
  1402. 37:39>> Right. Of course not. Of course not.
  1403. 37:41>> I'm going [laughter] to get mine, you
  1404. 37:42know? I don't
  1405. 37:42>> For sure, 100%. So, I guess to end this
  1406. 37:44conversation about injectable peptides,
  1407. 37:46we know people are going to go out and
  1408. 37:49and try to get peptides. It's so
  1409. 37:50popular. I see conversations about it
  1410. 37:52pop up every single day.
  1411. 37:54What should people be looking for when
  1412. 37:56they are trying to source it? Like if
  1413. 37:58whether it's with a medical practitioner
  1414. 37:59or with somebody else that like sells it
  1415. 38:01online or something, what questions
  1416. 38:03should they be asking?
  1417. 38:04>> I think we need to have people ask about
  1418. 38:06sourcing.
  1419. 38:07>> Mhm.
  1420. 38:07>> So, where is this peptide coming from?
  1421. 38:09Is it coming from a 503A pharmacy? Is it
  1422. 38:11coming from a research use only
  1423. 38:13pharmacy? If it is coming from a
  1424. 38:14research use only pharmacy, that's a red
  1425. 38:16flag.
  1426. 38:17>> Mhm.
  1427. 38:17>> I wouldn't do it. If your medication has
  1428. 38:19any particulate in it, if it's chunky,
  1429. 38:22don't use it. Right? If it's foamy,
  1430. 38:23don't use it. Right? I mean, I would
  1431. 38:25just say work with a educated clinician
  1432. 38:28who's not afraid of the hard questions,
  1433. 38:29who can tell you, "I don't know. Let me
  1434. 38:30look that up." Cuz that's a superpower
  1435. 38:32to be able to say, "I don't know. I can
  1436. 38:33look that up." We don't know it all.
  1437. 38:35This is an evolving field. Sourcing is
  1438. 38:37really important because I am seeing a
  1439. 38:38lot of people get it from just random
  1440. 38:41places online and they're not asking
  1441. 38:43enough questions.
  1442. 38:44>> Yeah. How about if somebody's just
  1443. 38:46recommending like one peptide to you? Or
  1444. 38:48if you go to a person that's selling it
  1445. 38:50and you're like, "I just I want to be on
  1446. 38:52copper peptides. I I just give that to
  1447. 38:54me." And they're like, "Okay." Is that a
  1448. 38:55red flag?
  1449. 38:56>> For me, yes. Because I know that it can
  1450. 38:59impact zinc levels. If you're not
  1451. 39:01looking at your patient's zinc levels,
  1452. 39:03that's really important because zinc and
  1453. 39:04copper can impact the way your blood
  1454. 39:07cells form.
  1455. 39:08So, for example, patients who have
  1456. 39:09chronically low white blood cell count,
  1457. 39:11sometimes you'll check their copper and
  1458. 39:12their zinc and they'll have low copper.
  1459. 39:14And when you address the low copper,
  1460. 39:16their white blood cells improve.
  1461. 39:18I think it's a red flag.
  1462. 39:19>> Yeah. Yeah. Like they need a maybe even
  1463. 39:21potentially check your labs. Say they
  1464. 39:23need need to check your labs, but also
  1465. 39:25maybe even suggest other things or
  1466. 39:26stacks.
  1467. 39:27>> Yes. Or like, how are you eating,
  1468. 39:29sleeping, pooping?
  1469. 39:31>> [laughter]
  1470. 39:31>> Like all the main health questions
  1471. 39:33first.
  1472. 39:33>> If someone's not asking about those core
  1473. 39:36functions, yeah. And they're just trying
  1474. 39:38to sell you a peptide and they If
  1475. 39:40someone tells you that a peptide is
  1476. 39:41going to do it all, you run. Right? It's
  1477. 39:43not going to do it all. You'll need to
  1478. 39:44do the work. The peptide's just going to
  1479. 39:46I always say it's sprinkles. You're the
  1480. 39:48cake that have to be baked. And you got
  1481. 39:50to be frosted. Then we can throw the
  1482. 39:51sprinkles on top.
  1483. 39:52>> Yeah, that makes sense. They're a tool,
  1484. 39:53like you keep saying. I I really like
  1485. 39:55that you're referring to injectable
  1486. 39:57peptides as a tool because I think
  1487. 39:58that's what people need to remember.
  1488. 39:59They're a tool in the overall toolbox.
  1489. 40:02And that's it.
  1490. 40:02>> and they're not going to replace
  1491. 40:04the daily behaviors that you have to do
  1492. 40:06that are work.
  1493. 40:06>> Being healthy.
  1494. 40:07>> Yeah.
  1495. 40:08>> Yeah. Maymay, thank you so much. We
  1496. 40:10could talk about this forever. So, and
  1497. 40:11and like I you sitting here, I already
  1498. 40:13have like other things I've heard about
  1499. 40:14and everything and I want to ask you
  1500. 40:15questions and stuff. So, I'm just going
  1501. 40:17to end this conversation right here and
  1502. 40:19I'm sure people will have more
  1503. 40:19questions, so we can always have you
  1504. 40:20back.
  1505. 40:21>> Thank you, Susan. I love chatting with
  1506. 40:22you.
  1507. 40:23>> I love chatting with you. Where can
  1508. 40:24people find you?
  1509. 40:25>> Oh, people can find me at Revere
  1510. 40:27Wellness or we actually started a
  1511. 40:29podcast too, inspired by you.
  1512. 40:30>> Love it.
  1513. 40:31>> plug it, it's called the Revere Rundown.
  1514. 40:32>> Yep.
  1515. 40:33>> It's basically answering common
  1516. 40:34questions that we get from our patients.
  1517. 40:36>> Yep.
  1518. 40:36>> And I have a very boutique practice. I
  1519. 40:39like to know all of my patients by name,
  1520. 40:41their kids, what they do, where they
  1521. 40:42are, like their lives. And so, in order
  1522. 40:44to touch more lives and truly my
  1523. 40:46delusional goal of like changing
  1524. 40:48people's lives for the better, I
  1525. 40:49launched this podcast called the Revere
  1526. 40:51Rundown to hopefully help others live
  1527. 40:52better.
  1528. 40:53>> Yeah, and you know, really quickly, I
  1529. 40:54think cuz we were talking about
  1530. 40:56about injectable peptides, but that's
  1531. 40:57not what you really focus on.
  1532. 40:59>> Yeah.
  1533. 40:59>> Will you just tell everybody why they
  1534. 41:00would want to maybe work with you?
  1535. 41:02>> Yeah. Oh, thank you. So, I focus on an
  1536. 41:04inside-out approach to wellness. That
  1537. 41:07looks differently for everybody, but
  1538. 41:08it's usually by looking at like hormone
  1539. 41:10optimization,
  1540. 41:11how you're pooping, how you're sleeping,
  1541. 41:13how you're eating, and then how we can
  1542. 41:15optimize your life. I truly want my
  1543. 41:16patients to have like the strong old
  1544. 41:19lady body, strong old man body cuz I see
  1545. 41:21their husbands too sometimes
  1546. 41:22occasionally. I primarily work with
  1547. 41:24women, but they're always like my
  1548. 41:25husband's jealous or my boyfriend's
  1549. 41:26jealous. Can he come see you? My son
  1550. 41:27wants to come see you. And then I'm
  1551. 41:28like, of course, you know, cuz we treat
  1552. 41:29the whole family.
  1553. 41:30>> Yeah, I focus on an inside-out approach.
  1554. 41:32I truly believe that if you're healthy
  1555. 41:33on the inside, not just your body, but
  1556. 41:35your mind,
  1557. 41:36then it shows on the outside and that's
  1558. 41:39what we do, optimal wellness that way.
  1559. 41:41>> Thank you so much.
  1560. 41:42>> Thank you, Susan. I appreciate it.
  1561. 41:44>> Thanks for watching this episode of Glow
  1562. 41:45Lab. If you enjoyed it, make sure you
  1563. 41:47subscribe, rate and review, and of
  1564. 41:48course, share it with a friend that way
  1565. 41:50we can keep the conversation going with
  1566. 41:51amazing guests.

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