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The BEST Ingredient Combos for Every Skin Concern | Wrinkles, Hair Loss, Acne, & More — Transcript

by Doctorly · 2,415 words · 385 segments · language en · Watch on YouTube

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  1. 0:00The most perfect ingredient combinations
  2. 0:04for your skin concerns. We always talk
  3. 0:05about the single ingredient that does it
  4. 0:07all, but the practically some
  5. 0:09ingredients just work better together to
  6. 0:11achieve the results. So, we're going to
  7. 0:12be talking about by skin concern,
  8. 0:14whether you have dark spots, wrinkles,
  9. 0:16texture, which two ingredients would you
  10. 0:19use together to achieve the best
  11. 0:21efficacy in your routine. That'll
  12. 0:22simplify things and give you really the
  13. 0:24best results.
  14. 0:24>> Even if a single ingredient does
  15. 0:26everything, it's still not enough to do
  16. 0:27everything completely well. So, we'll
  17. 0:30talk about what the hero ingredient is,
  18. 0:32what its best pair is, and what you
  19. 0:33should be doing for your skin regardless
  20. 0:35of your skin concern. So, the best skin
  21. 0:37care pairs, here we go. Here we go.
  22. 0:44First up, rules of engagement. Can we
  23. 0:47repeat ingredients?
  24. 0:50>> Think we have to.
  25. 0:51>> Oh, of course. Yeah, so of course we can
  26. 0:52repeat ingredients per skin concern. Of
  27. 0:54course, yes. So, to kick it off, the
  28. 0:57perfect duo for wrinkles.
  29. 1:00>> Okay. So,
  30. 1:02this is like real-world practical versus
  31. 1:04maximizing efficacy. I still would have
  32. 1:07to say your retinoid, and I'll say
  33. 1:09tretinoin, plus your exfoliant, glycolic
  34. 1:12acid. I don't think there's a more
  35. 1:13powerful pair.
  36. 1:14>> Ooh, okay. Ooh, ah, that's surprising. I
  37. 1:18was [snorts] thinking retinoid,
  38. 1:20definitely, but potentially you could
  39. 1:22say vitamin C collagen building, but you
  40. 1:24could also go peptide direction with
  41. 1:25this one, too. You could go copper
  42. 1:27peptide or even other peptide, Matrixyl
  43. 1:30peptide, any other signaling peptide.
  44. 1:32Exfoliation, I'm like, "Ooh, that's
  45. 1:34texture more for me."
  46. 1:35>> Mhm, that's good. That's good. I'm going
  47. 1:37to go vitamin C retinoid as perfect
  48. 1:41combo for wrinkles.
  49. 1:42>> Yeah, I'm still going to go with
  50. 1:44um retinoids and glycolic acid because
  51. 1:46these exfoliators also do signal
  52. 1:48collagen building in addition to their
  53. 1:51direct keratolytic effect of smoothing
  54. 1:54out texture at the top of the skin, so
  55. 1:56>> That's fair. Dark spots, discoloration,
  56. 1:59hyperpigmentation, melasma, perfect duo
  57. 2:02of ingredients. Let's do
  58. 2:03over-the-counter first, and then let's
  59. 2:06do prescription.
  60. 2:07>> So, over-the-counter, I still think
  61. 2:09retinal, let's just air on efficacy
  62. 2:12again, is going to do them a lot of
  63. 2:14heavy lifting here, decrease pigment
  64. 2:15production in a unique way, increase
  65. 2:17skin cell turnover, removing existing
  66. 2:18pigment. And then,
  67. 2:21over-the-counter, I'm like, protection
  68. 2:24or brightening? Protec-
  69. 2:25>> Oh, well.
  70. 2:25>> I'm like, what's more important? We're
  71. 2:26picking two things here. So, I'm going
  72. 2:28to go with tinted sunscreen. So, I'm
  73. 2:30going to air on protection plus using
  74. 2:32the retinal for treatment as opposed to
  75. 2:34picking two treatment options. Tinted
  76. 2:36sunscreen protects from UV rays,
  77. 2:38protects from visible light, giving an
  78. 2:39added benefit specifically for your dark
  79. 2:41spots concerns.
  80. 2:42>> I think that's absolutely fair. Every
  81. 2:44study we've done on Remedy for Dark
  82. 2:46Spots, the patient was using a tinted
  83. 2:49sunscreen in the morning, and they were
  84. 2:50using Remedy for Dark Spots at night.
  85. 2:51So, I don't think you can use any dark
  86. 2:54spot treatment without that. And I would
  87. 2:55say, one ingredient over-the-counter
  88. 2:57that does dark spots, both the blocking
  89. 2:59of formation of dark spots and the
  90. 3:00removal of dark spots, would be a
  91. 3:01retinoid. And then, from an ingredient
  92. 3:03perspective, I'd pair it with any potent
  93. 3:05tyrosinase inhibitor, like arbutin or
  94. 3:08kojic acid. And on the prescription
  95. 3:09side, then you take a prescription
  96. 3:10tretinoin with a hydroquinone, which is
  97. 3:13a potent tyrosinase inhibitor. And that
  98. 3:14is the best combination, but you can
  99. 3:16only use that for a short period of
  100. 3:17time. And so, I would say, I agree with
  101. 3:19you. Sunscreen is critical path on any
  102. 3:22of this.
  103. 3:22>> Perfect.
  104. 3:23>> One of the greatest purchases I've ever
  105. 3:25made, and it's the electric toothbrush.
  106. 3:27I bought it actually for the first time
  107. 3:28at the age of 29, and I've never looked
  108. 3:30back. Now, if you already have an
  109. 3:32electric toothbrush, you know these take
  110. 3:33up a ton of space on the counter,
  111. 3:34they're not very aesthetic, they're
  112. 3:36impossible to travel with. And this is
  113. 3:38why, this is one of the coolest devices
  114. 3:40I've ever seen, the Suri toothbrush. So,
  115. 3:42when I first bought an electric
  116. 3:43toothbrush, it felt like an investment,
  117. 3:44but I really do believe it was worth it.
  118. 3:47And this one in particular, it is easy
  119. 3:49to carry with you. It has this
  120. 3:51incredible case with it. It also has
  121. 3:5230,000 sonic vibrations per minute for a
  122. 3:55deep but very gentle clean. And it has
  123. 3:57touch sense so you don't really overdo
  124. 3:59it. So you really don't want to be
  125. 4:00irritating your gums or your teeth and
  126. 4:01so it makes sure that you're not using
  127. 4:03too much pressure, too much force, or
  128. 4:04too much vibration if you're not using
  129. 4:06it correctly.
  130. 4:07>> It's powerful, it's gentle, it's a
  131. 4:08dentist approved clean, and it actually
  132. 4:10has a battery that lasts up to 4 weeks.
  133. 4:13>> Now I'm really into aesthetic bathrooms
  134. 4:14and I don't like things cluttering all
  135. 4:16over my counter and I have lots of skin
  136. 4:17care products there already. And one of
  137. 4:19my favorite things is the magnetic
  138. 4:20mirror mount. So you can attach this to
  139. 4:22your mirror and it basically sticks onto
  140. 4:24your mirror and you can keep your
  141. 4:25toothbrush there, which is really cool.
  142. 4:28>> And because we travel so much, we're
  143. 4:29actually traveling right now as we're
  144. 4:31filming. This is a huge game changer for
  145. 4:33us because not only does the battery
  146. 4:34last so long, it also has really
  147. 4:36incredible packaging that's so
  148. 4:37convenient to bring, but it also has a
  149. 4:39UVC cleaning mechanism. So it actually
  150. 4:41cleans it while you travel with it. If
  151. 4:43you ever put a moist toothbrush into a
  152. 4:45container, you know that you can get
  153. 4:47build up in there. And so having the UVC
  154. 4:49helps to decontaminate while you're
  155. 4:51traveling.
  156. 4:51>> It basically makes your whole routine
  157. 4:53and lifestyle simpler and you can use
  158. 4:55our code in the description for 15% off
  159. 4:57Surri today.
  160. 4:58>> So check it out below. You'll see why we
  161. 5:00love it so much. Now let's get back to
  162. 5:01the video.
  163. 5:02>> Next up, let's go with acne.
  164. 5:05>> Really some great over-the-counter
  165. 5:06options here for acne and I'll let you
  166. 5:09pick the first two this time.
  167. 5:10>> Ooh, this one is actually kind of
  168. 5:12exciting. I hadn't anything exciting to
  169. 5:13say about acne in a long time because
  170. 5:15the videos that we made 5 years ago play
  171. 5:17well today. I actually don't think much
  172. 5:19has changed in the acne space other than
  173. 5:20some products have different textures,
  174. 5:22but from a performance perspective,
  175. 5:24nothing has come out that I'd said is
  176. 5:25better than before in acne until today,
  177. 5:28I would say. So you don't even know what
  178. 5:29I'm going to say.
  179. 5:30>> Differin.
  180. 5:31>> Don't. Be with us, it's a product.
  181. 5:32>> Differin dropped Epiduo over the
  182. 5:34counter. This is huge news.
  183. 5:36>> This is the biggest news is
  184. 5:37>> I guess theoretically you could have
  185. 5:38done this yourself at home, but
  186. 5:40adapalene, one of the most effective
  187. 5:42acne treatment at home, period.
  188. 5:44>> Followed by benzoyl peroxide and then
  189. 5:47depending on how your skin tolerates it,
  190. 5:49you may choose other things as number
  191. 5:50two after adapalene. But now Differin
  192. 5:53has Epiduo available over the counter.
  193. 5:54It used to only be a prescription, so
  194. 5:55it's adapalene plus benzoyl peroxide in
  195. 5:57one product. And so I think lethal
  196. 5:59combinations when it comes to not lethal
  197. 6:01as in it will kill you, but lethal as in
  198. 6:03lethal for your acne is adapalene plus
  199. 6:06benzoyl peroxide, adapalene plus sulfur,
  200. 6:08adapalene plus salicylic acid depending
  201. 6:12on what your skin can tolerate. But I do
  202. 6:13think benzoyl peroxide of those is the
  203. 6:16most effective and then aselaic acid
  204. 6:18kind of falls in there as well.
  205. 6:19>> Yeah, I agree. So benzoyl peroxide and
  206. 6:21adapalene are the two hero ingredients.
  207. 6:23Just purely speaking in terms of
  208. 6:25efficacy, I don't think that there is
  209. 6:27anyone else competing for that top tier
  210. 6:29spot. My thought was that I just can't
  211. 6:32decide if I love benzoyl peroxide in a
  212. 6:33cleanser. I just think it works so well
  213. 6:36and it's a complimentary step. So
  214. 6:38whether you're using adapalene plus
  215. 6:39benzoyl peroxide leave-on in the
  216. 6:41Differin form or whether you're using
  217. 6:42adapalene plus benzoyl peroxide in your
  218. 6:44cleanser, I think both are going to be
  219. 6:47the most effective cornerstone for your
  220. 6:48acne treatment at home.
  221. 6:50>> Actually just I mean retinoid plus
  222. 6:52aselaic. Adapalene at night, aselaic in
  223. 6:55the morning.
  224. 6:56>> I still think benzoyl peroxide
  225. 6:58specifically for acne would outperform.
  226. 7:00>> Uh benzoyl peroxide definitely
  227. 7:02outperforms aselaic acid especially when
  228. 7:03it comes to inflammatory acne, but you
  229. 7:05only like it in a cleanser. I would say
  230. 7:07leave-on.
  231. 7:08>> No, I like it both. Like like
  232. 7:11It work both ways, but I just think
  233. 7:14because cleansing step is a step you're
  234. 7:16already doing, it helps you put an
  235. 7:18ingredient that you should use into a
  236. 7:20step that already exists and it frees up
  237. 7:22a step in the rest of your skin care
  238. 7:24routine.
  239. 7:25>> benzoyl peroxide cleanser, adapalene
  240. 7:27leave-on. That's the combo.
  241. 7:29>> Right, yeah.
  242. 7:30>> Agreed. And then as a third, aselaic in
  243. 7:32the morning.
  244. 7:33>> Okay,
  245. 7:33>> [laughter]
  246. 7:33>> so still a third. Okay, great.
  247. 7:35>> And then prescription when it comes to
  248. 7:36acne, it's still going to be a retinoid
  249. 7:38whether it's a stronger retinoid like
  250. 7:40tretinoin, higher strength of adapalene
  251. 7:42or even tazarotene, and then you're
  252. 7:43going to pair that again with benzoyl
  253. 7:45peroxide or azelaic acid because or
  254. 7:48clindamycin, some type of antibacterial
  255. 7:50agent. And then we have other oral
  256. 7:52medications that come after that, but
  257. 7:53the combination and the theory is still
  258. 7:55sort of the same at prescription. We
  259. 7:56just have higher strengths of the
  260. 7:58options that are available over the
  261. 7:59counter.
  262. 8:00>> So, not quite revisiting a problem, but
  263. 8:03perhaps revisiting a pair is going to be
  264. 8:06texture. Now, when we think of texture,
  265. 8:08it's a really hard one to actually
  266. 8:09describe, I think, because it sometimes
  267. 8:11it's pores, sometimes it's built up just
  268. 8:13dead retained stratum corneum. Some
  269. 8:15people actually incorporate fine lines
  270. 8:16into texture as well, and even if you
  271. 8:18try to search for an image like for
  272. 8:20usage of textured skin, it's difficult
  273. 8:22because there's so many different
  274. 8:24things. Now, the main components for
  275. 8:25this, I think, are going to be
  276. 8:26exfoliation, removing built-up skin
  277. 8:29cells, just improving the smoothness of
  278. 8:31your skin. And for that, I go back to my
  279. 8:34first pair, which is retinoids
  280. 8:35exfoliants, and we can say retinol,
  281. 8:37retinal, and an alpha hydroxy acid.
  282. 8:40>> 100% retinoids plus alpha hydroxy acids,
  283. 8:43the number one thing that you can do for
  284. 8:45texture overall. And so,
  285. 8:46over-the-counter, you can even use
  286. 8:48adapalene in this case, even though it's
  287. 8:49for acne, it does really well for
  288. 8:50texture. Or any retinol or retinal-based
  289. 8:53product is going to do really well here.
  290. 8:55And then you combine that with a higher
  291. 8:57strength potential exfoliating acid.
  292. 9:00Glycolic acid is going to be the most
  293. 9:01effective, but if you have drier skin,
  294. 9:03you may like lactic acid. If you have
  295. 9:04sensitive skin, you may like the
  296. 9:06polyhydroxy acids like gluconolactone or
  297. 9:08lactobionic acid. I think from an
  298. 9:10efficacy standpoint, glycolic acid plus
  299. 9:12adapalene would be absolute the best
  300. 9:15thing you could do over the counter.
  301. 9:17>> Yeah, I agree. Those are great tools
  302. 9:18that would address all the changes of
  303. 9:19texture. And if you're going to build a
  304. 9:21routine surrounding those ingredients,
  305. 9:23that would be good, but I would start
  306. 9:24with those two.
  307. 9:25>> Large pores, the impossible thing to
  308. 9:28treat.
  309. 9:28>> Yeah, pores are so structural. It's not
  310. 9:31just the oil gland at the bottom, it's
  311. 9:32the whole structure surrounding it. And
  312. 9:34so here, limiting the conversation to
  313. 9:37topicals, I think structurally,
  314. 9:40okay, I'll go with adapalene and
  315. 9:42salicylic acid as my two. So, adapalene,
  316. 9:44having all those changes of retinoids we
  317. 9:46talked about already, salicylic acid,
  318. 9:48depending on how you use it, will help
  319. 9:49remove oil from the pores, help decrease
  320. 9:51oil production a bit, and also add some
  321. 9:53exfoliation to impact the structure of
  322. 9:55the pore itself.
  323. 9:56>> Yeah, totally agree with you. Hair loss.
  324. 9:59>> Hair loss. Oh, oh, okay. Hair loss, I
  325. 10:02have topical minoxidil, obviously the
  326. 10:04gold standard, every other ingredient is
  327. 10:06compared to that. And I still love The
  328. 10:08Ordinary Hair Peptide Serum. It's not a
  329. 10:09single ingredient, but it's just a
  330. 10:11complimentary blend of peptides in one
  331. 10:14step that I think supports minoxidil
  332. 10:16really well.
  333. 10:17>> Yeah, and they work by different
  334. 10:18mechanisms, minoxidil, so they actually
  335. 10:20are complimentary. So, some of the
  336. 10:22things that we're talking about in this
  337. 10:23video are they're ingredients that work
  338. 10:26by different mechanisms to achieve the
  339. 10:28objective. So, for example, when we're
  340. 10:30talking about exfoliation, it's, you
  341. 10:31know, retinoids increasing skin cell
  342. 10:32turnover, decreasing the stickiness,
  343. 10:34being comedolytic to some extent, and
  344. 10:36then you have the exfoliating acid that,
  345. 10:38you know, is additive because of its
  346. 10:39comedolytic properties. Then you have,
  347. 10:41with this, minoxidil working by a
  348. 10:43totally different mechanism than The
  349. 10:45Ordinary Peptide Serum. Whereas, like,
  350. 10:47if you took Kopexil, for example, also
  351. 10:50known as aminexil, works by similar
  352. 10:52mechanism as minoxidil, so you don't
  353. 10:54necessarily need to use those two
  354. 10:55together, but Ordinary Peptide Serum
  355. 10:57plus minoxidil to really achieve those
  356. 10:59over-the-counter topical hair loss
  357. 11:00goals.
  358. 11:01>> So, what we've given you, basically, is
  359. 11:03if you're building your skin care
  360. 11:04routine around a specific skin care
  361. 11:05concern, which is how you should always
  362. 11:07do it, these are some of the best pairs
  363. 11:09to provide a cornerstone and foundation
  364. 11:11for you to start with. You might need to
  365. 11:13do more, you might want to do more, but
  366. 11:14if you're going to pick two things,
  367. 11:16these might be the best places to start.
  368. 11:18>> Now, we mentioned lots of ingredients
  369. 11:20here, and we'll actually put links below
  370. 11:22of products that have those ingredients
  371. 11:24that you can then use in your routine to
  372. 11:26achieve your goals. So, hopefully you
  373. 11:27found this helpful. I do think with two
  374. 11:28ingredients, and sometimes three
  375. 11:30ingredients, depending on how complex
  376. 11:31the condition is, you can probably
  377. 11:33achieve the goals and usually one
  378. 11:34ingredient's not going to do it all, but
  379. 11:35when you get to two ingredients, you
  380. 11:37really can really treat most of the
  381. 11:39causes of skin conditions that are out
  382. 11:40there. So, thank you all so much for
  383. 11:41tuning in. Please like, comment, and
  384. 11:42subscribe, and we'll see you in the next
  385. 11:44video. We'll see you next time.

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