Summary of Chapter 3 — Transcript

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1. 0:02in this chapter we started looking at
2. 0:05the histamine two blockers and they're
3. 0:08not able to affect the cell without
4. 0:11being absorbed into the system so we
5. 0:14took the opportunity to start developing
6. 0:17a good foundation of pharmacokinetics we
7. 0:20simply aimed to get a good picture of
8. 0:24each process the absorption distribution
9. 0:28metabolism and excretion of our
10. 0:31medications
11. 0:32and don't worry if you didn't catch
12. 0:35everything
13. 0:36understanding pharmacokinetics is very
14. 0:39difficult so I'll take you through a
15. 0:41review of pharmacokinetics using the
16. 0:44proton pump inhibitors as the example in
17. 0:47the next chapter I think you'll find
18. 0:49that you know a lot more about the topic
19. 0:52than you realize
20. 0:54and since the histamine 2 antagonists
21. 0:57have a common suffix which is tidene
22. 1:01t-i-d-i-n-e we took the opportunity to
23. 1:04start developing the skill of finding
24. 1:07the portion of the generic name that
25. 1:09tells us which drug class the medication
26. 1:12belongs to we also learned a bit more
27. 1:15about the potential selective nature of
28. 1:18some drugs as we were discussing the
29. 1:20histamine 2 blocking drugs recall that
30. 1:24the histamine two blockers do not have
31. 1:27an affinity for the histamine one
32. 1:29receptor
33. 1:31and as such they don't have the actions
34. 1:35that are commonly associated with the
35. 1:37antihistamines
36. 1:40recall that the medications we refer to
37. 1:43as antihistamines bind to the H1
38. 1:48receptor and as such they decrease the
39. 1:52runny nose the itchy eyes and
40. 1:54inflammation that's caused by the
41. 1:55histamine in the nasal passages
42. 1:59well that histamine one receptor is a
43. 2:03slightly different receptor and the
44. 2:05histamine II receptor blockers act
45. 2:08almost exclusively on the histamine II
46. 2:12receptor
47. 2:13finally we learned a bit about the
48. 2:16actions indications contraindications
49. 2:19and side effects of the histamine 2
50. 2:22blocking drugs
51. 2:24in the next chapter we'll get a really
52. 2:27good picture of enzymatic Inhibitors and
53. 2:31take one specific enzymatic inhibitor
54. 2:35called the proton pump inhibitor