Oral Pathology | Developmental Conditions | INBDE, ADAT — Transcript
Full transcript
- 0:00hey guys it's Ryan welcome back sorry
- 0:04it's been a while I got a new computer
- 0:06and a new microphone so maybe you'll
- 0:09notice a little bit of a change in the
- 0:11audio quality hopefully for the better
- 0:13this will be the first of many videos on
- 0:16a really cool topic oral pathology this
- 0:20is something that comes up on nbda part
- 0:232 on the 8th at the seated ESC and even
- 0:26part one of the boards and of course
- 0:29this is something that will come in
- 0:31handy when working with patients
- 0:32recognizing when something seems off and
- 0:35knowing when to biopsy but I'm hearing
- 0:38these videos for preparing for the exams
- 0:40I mentioned especially part to the
- 0:42National boards
- 0:43I'll be focusing on only the highest
- 0:46yield things you should know for each
- 0:48condition if you like this type of info
- 0:51you may want to check out most ways
- 0:53review for the NVDA part too much of the
- 0:56info I'll be going over is adapted from
- 0:58that book and I'll leave a link in the
- 1:00description below for it for you to
- 1:03check it out so these are all of the
- 1:06categories we're going to be talking
- 1:07about one video at a time and organized
- 1:11by tissue type and then by the type of
- 1:14lesion reactive infectious immuno logic
- 1:17and so on basically you can kind of
- 1:20think of it like we're starting with
- 1:22developmental conditions things that are
- 1:26either soft or hard tissue defects that
- 1:28occur during the development of an
- 1:30individual either before or after birth
- 1:33then we go over basically going from
- 1:36outside to inside from mucosa then we go
- 1:40to submucosa and glands then we talk
- 1:43about the teeth and then we talk about
- 1:44bone and finally we'll go over
- 1:46hereditary conditions that are passed on
- 1:49through genes so let's begin so the
- 1:53first one we're going to talk about is
- 1:54cleft lip approximately one in 1,000
- 1:58births so relatively rare unilateral is
- 2:03about eighty percent of the time whereas
- 2:06bilateral is only about twenty percent
- 2:08of the time so you're gonna see
- 2:09unilateral
- 2:10often with cleft lip and most
- 2:13importantly this is a lack of fusion
- 2:15between the medial nasal process and the
- 2:19maxillary process so if we look at this
- 2:23image down here that's basically between
- 2:27this philtrum area which is under the
- 2:29middle of the nose and the lateral lip
- 2:32cheek area so this is between the medial
- 2:35nasal process and the maxillary process
- 2:37or prominence which are embryologic
- 2:40structures that will eventually fuse
- 2:42together to form the face and this is a
- 2:45lack of fusion of those embryo logical
- 2:48structures and then cleft lip it's
- 2:51approximately one in two thousand births
- 2:53so a little bit more rare than cleft lip
- 2:56and two lack of fusion between palpable
- 2:58shelves which makes sense because it's
- 3:01the cleft palate so then we can look at
- 3:03this view over here this is looking at
- 3:05the roof of the mouth and you can see
- 3:08how a unilateral cleft will go off to
- 3:11one side and kind of coalesce with one
- 3:14of the nostrils and the bilateral cleft
- 3:16will go and split the palate in two with
- 3:20this inner maxillary segment separated
- 3:23in a bilateral cleft because this again
- 3:26involves middle nose the philtrum middle
- 3:30of the lip and in a maxillary segment
- 3:32which is part of the medial nasal
- 3:35process so the two palatal shelves are
- 3:37on either side of that cleft then lip
- 3:44pits or imaginations at either the
- 3:47common shares which are the corners of
- 3:49the mouth or near the midline now all
- 3:52the syndromes that I'm going to be
- 3:53talking about in this oral pathology
- 3:56video series I'll have them bolded and
- 3:58I'll kind of list them as sort of a math
- 4:00equation basically in addition the sum
- 4:04of a certain amount of conditions that
- 4:07need to be met for it to be considered a
- 4:09syndrome so and I may not pronounce all
- 4:13these correct so sorry about that but
- 4:16the van der woodsen Jerome in valves
- 4:18both a cleft either lip or palate or
- 4:21both and the presence of lip
- 4:24it's as seen in this picture now four
- 4:29nice granules are ectopic sebaceous
- 4:31glands if you remember this it's
- 4:33probably all you need to know they're
- 4:36completely benign no treatment necessary
- 4:38at all but that's sufficient to know and
- 4:42sort of knowing this pretty classic
- 4:44condition either on buccal mucosa or
- 4:47labeled labial mucosa inside the lips
- 4:50those are the characteristic locations
- 4:53for these kind of things
- 4:55Luco edema is another thing just to know
- 4:58a couple of key buzz phrases for it it's
- 5:02basically this white or in this picture
- 5:05whitish grey ademma tiss which means
- 5:07fluid the collection of fluid lesion of
- 5:10buccal mucosa so again very common in
- 5:13buccal mucosa and it dissipates when the
- 5:16cheek is stretched so if you take two
- 5:18fingers stretch this out the lesions
- 5:21looks like it kind of goes away for a
- 5:23brief moment and that's because of the
- 5:25collection of this dimittis this fluid
- 5:28in this area lingual thyroid is a
- 5:32thyroid tissue mass at the midline base
- 5:35of the tongue and importantly it's
- 5:38located along the embryonic path of
- 5:41thyroid ascend so if we look at this
- 5:45diagram of thyroid ascent we don't need
- 5:49to know all the specifics but it starts
- 5:52out at the foramen cecum of the tongue
- 5:55the midline base of the tongue and
- 5:57during development it goes down it wraps
- 6:01around the highway bone and goes down a
- 6:03little bit further and eventually ends
- 6:05up where the thyroid should be and that
- 6:08is below the laryngeal cartilage area
- 6:11around the trachea but it can get stuck
- 6:14anywhere along this path of descent so
- 6:18it could just not go anywhere and get
- 6:20stuck in the back of the tongue like
- 6:23this or it could end up somewhere along
- 6:27that path at say the neck area and so a
- 6:31thyroid thyroid glossa Luxus is an
- 6:35example of this so this would be a
- 6:38mid-line neck swelling and again located
- 6:41along the embryonic path of thyroid
- 6:43ascend so langral thought lingual
- 6:46thyroid and thyroglossal duct cysts are
- 6:48manifestations of an improper path of
- 6:53the thyroid geographic tongue also goes
- 7:00by two other names benign migratory
- 7:02bless itis and erythema migrans and
- 7:06sometimes the alternative names are sort
- 7:09of cumbersome but in this case it
- 7:11actually helps helps us remember what it
- 7:14looks like and how it acts so this is a
- 7:17pretty nice characteristic photo has
- 7:20these white annular lesions which means
- 7:23their white rings surrounding central
- 7:26red islands that literally migrate over
- 7:29time and they'll move around on the
- 7:31tongue and this is how you get this
- 7:33migratory migrants terminology and also
- 7:38the ear athina referring to the redness
- 7:40of the tongue
- 7:41occasionally hurts and burns
- 7:44unfortunately outside of a little bit of
- 7:46symptomatic and dietary changes there
- 7:49really is no treatment for this
- 7:51condition fissure tongue is relatively
- 7:57more common than some of the other ones
- 7:59we talked about has a folds and furrows
- 8:02of the tongue dorsum the the top surface
- 8:06of the tongue here more important it's
- 8:09involved in the syndrome called Mel
- 8:11curse and Rosenthal syndrome and has
- 8:14Fisher tongue granulomatous colitis
- 8:17which is basically lip inflammation
- 8:20involving granulomas granulation tissue
- 8:23and facial paralysis how I remember this
- 8:28is this is not an not an acronym but a
- 8:37helpful way to think about this is Mel's
- 8:42Mel's Belle's so you can think of Mel
- 8:47Corson and Belle's referring to Belle's
- 8:52which is another type of facial
- 8:54paralysis involving the facial nerve and
- 8:57you can think of rows or rosy-red and
- 9:04that would be referring to the rosenthal
- 9:08part of the syndrome and the redness
- 9:10that's affecting the lips because this
- 9:14granulomatous colitis is basically this
- 9:17lip inflammation that involves red
- 9:19swollen lips so if you think about the
- 9:22bells Bell's palsy
- 9:24facial paralysis rosy red red lips
- 9:28colitis meaning lip inflammation you can
- 9:31kind of put all this stuff together
- 9:32maybe a little bit better so hopefully
- 9:35that helps you remember some of these
- 9:37weirder name syndromes I'll try to throw
- 9:39in some helpful things to kind of
- 9:41they're silly things to help remember it
- 9:45so next we're going to talk about
- 9:46angiomas so this is a kind of it was
- 9:49confusing for me is there a bunch of
- 9:52different types of angiomas and I can't
- 9:53really get a grasp on what they all were
- 9:55is they're very different in
- 9:57presentation but if we break this word
- 10:00down Angie is a prefix meaning vessels
- 10:04and oma is a suffix meaning a tumor so
- 10:09literally it's translated to a tumor
- 10:12composed of blood vessels or lymph
- 10:14vessels there are two types of vessels
- 10:17in the human body so any angioma is
- 10:21either going to be a tumor of blood
- 10:24vessels or lymph vessels a cherry
- 10:27angioma is extremely common super benign
- 10:30most of us have them somewhere and it's
- 10:34basically a red mole so it an incredibly
- 10:37really sounds silly to call it a tumor
- 10:39but an incredibly small tumor of small
- 10:43little capillaries and blood vessels
- 10:45that accumulate and just form this small
- 10:48little mole on our skin a hemangioma is
- 10:52a congenital focal proliferation of
- 10:55capillaries so again it's involving
- 10:57blood vessels but a little bit larger
- 10:59scale
- 10:59now most undergo involution has an
- 11:03infinite or child ages
- 11:05but persistent lesions should be excised
- 11:08mostly for aesthetic reasons so we have
- 11:13cherry angioma hemangioma
- 11:16and now lymph angioma so we talked about
- 11:20the blood vessel proliferation and now
- 11:23let's talk about congenital focal
- 11:24proliferation of lymph vessels so oral
- 11:28lymph angiomas are actually super rare
- 11:30they manifested these little purple
- 11:33spots on the tongue more common would
- 11:36probably be when it occurs on the neck
- 11:39it looks it's just basically a another
- 11:42neck swelling and it's called a cystic
- 11:44hygroma so that one's kind of a little
- 11:48bit different nomenclature but cystic
- 11:52hygroma is technically a lymph angioma
- 11:54of the neck and again we have another
- 11:59syndrome
- 12:00this time sturge-weber syndrome and this
- 12:03involves angiomas of the leptomeninges
- 12:05which are the arachnoid and Pia mater
- 12:08and just for reference to the two most
- 12:12internal of the meninges and then they
- 12:18also the syndrome also involves angiomas
- 12:21of the skin along the distribution of
- 12:24the trigeminal nerve so v1 v2 v3 the
- 12:29angiomas of the syndrome can also be
- 12:34referred to as an cephalo trigeminal
- 12:37angio mitosis that's really it sounds
- 12:41really complicated but encephalo
- 12:43referring to brain trigeminal referring
- 12:46to this nerve and angio mitosis just
- 12:49referring to the presence of angiomas in
- 12:52relation to those structures so
- 12:55sturge-weber syndrome all about angiomas
- 13:00next we have exostosis and tour eye and
- 13:03this is the excessive cortical bone
- 13:07growth seen in these pictures so this
- 13:10they're basically named based on where
- 13:12they occur this would be a buccal
- 13:14exostosis
- 13:16a very severe one in this case
- 13:19and this would be a palatal Taurus again
- 13:23pretty pretty severe they're usually not
- 13:25quite this large but just for pictures
- 13:29sake that's those are two examples next
- 13:35we have a dermoid cyst and this is a
- 13:38mass in the midline and it can be either
- 13:40intraoral or extra oral it depends on a
- 13:43location where the cyst originates so if
- 13:47it originates above the mylohyoid muscle
- 13:50it presents in the floor the mouth like
- 13:53same here if it develops below the
- 13:56mylohyoid then it would be a mass
- 13:59another yet another mass in the upper
- 14:02neck so as you can as you can see here
- 14:04there are quite a few of these cysts and
- 14:07developmental conditions that manifest
- 14:10not only internally but also cervical e
- 14:13in the neck so dermoid cyst is pretty
- 14:16interesting it contains any variety of
- 14:20adnexal structures which included like
- 14:22hair sebaceous glands seminiferous
- 14:35tubule
- 14:36which is something we'll talk about in
- 14:38another video but this cyst in
- 14:40comparison to arraign yellow which also
- 14:42presents in the floor of the mouth has a
- 14:44doughy consistency and that's because of
- 14:47the things that it contains within it
- 14:50next we have the branchial cyst and this
- 14:53is also very often contradicted to the
- 14:58thyroglossal duct cyst which was the
- 15:00midline neck swelling this is a lateral
- 15:02neck swelling and it's because it's
- 15:04related to the branchial arches which
- 15:09are synonymous with the pharyngeal
- 15:10arches which are part of the head and
- 15:13neck
- 15:13embryology it's an epithelial cyst
- 15:17within a lymph node of the neck and you
- 15:20can think of when the doctor palpates
- 15:22around around your neck they're always
- 15:25running their fingers along the lateral
- 15:27aspect of the neck so that's why you can
- 15:31connect that to why the brachial
- 15:32this is on the lateral side also
- 15:35remember that all cysts by definition
- 15:37have an epithelial lining so all the
- 15:40since we've talked about have epithelial
- 15:42lining this one in this case is
- 15:44stratified squamous epithelium I don't
- 15:47think that's too important but just just
- 15:51for your own edification I guess and
- 15:54next we have oral lympho epithelial cyst
- 15:57which is basically the equivalent the
- 16:00intraoral equivalent of the bronchial
- 16:02assist because now it's also an
- 16:04epithelial assist within lymphoid tissue
- 16:07this time it's in oral mucosa not on the
- 16:10lateral neck so if you think of lymphoid
- 16:14tissue intra orally the paletine and
- 16:17lingual tonsils come to mind and so
- 16:19those are the most common regions that
- 16:22these little assists are found next is
- 16:27Stephanie bone defect which is a seems
- 16:30to be a really real favorite of test
- 16:32makers and it's a radial lucency and the
- 16:36posterior mandible below the mandibular
- 16:39canal and it looks like it could be a
- 16:42cyst it almost looks like it's
- 16:43coordinated in this image but it's not
- 16:46it's due to the lingual concavity of the
- 16:48jaw just being so severe that it appears
- 16:51on an x-ray this case in a panoramic and
- 16:56it just it seems like it's something
- 16:59that should be investigated but it's
- 17:01actually just a variation of normal
- 17:04Anatomy nasal Palatine duct cyst is a
- 17:09characteristically heart shaped
- 17:11radial lucency in the nasal palatine
- 17:14canal it's caused by syste fication of
- 17:17canal remnants treatment for this would
- 17:20be surgical excision globulin maxillary
- 17:25lesion is a fancy clinical term denoting
- 17:29any radial lucency
- 17:30between and this is very specific the
- 17:33maxillary canine and the maxillary
- 17:35lateral incisor
- 17:38that's very specific and this is not a
- 17:41diagnosis the other things we talked
- 17:43about our diagnosis this is just a
- 17:45clinical description of this exact
- 17:49manifestation and lastly we have
- 17:54traumatic bone cyst which is another
- 17:56favorite of test makers is also called
- 17:59simple bone cyst and idiopathic bone
- 18:02cavity which are important synonyms it's
- 18:05a large radial lucency and it's
- 18:07scalloped around roots that's probably
- 18:10the most important thing you need to
- 18:11know about this one
- 18:13it does not have an epithelial lining so
- 18:17like the other ones the other cysts I
- 18:19said they do have an epithelial lining
- 18:21this is technically a pseudocyst it's
- 18:24although it's named a cyst it's not
- 18:26technically by definition a cyst it's
- 18:30usually in the mandible of teenagers
- 18:32associated with some sort of jaw trauma
- 18:34by sports or something like that the
- 18:38treatment would be to aspirate first
- 18:40determine that it's fluid filled it has
- 18:43blood in it and then just monitor and
- 18:46this thing is they're typically nothing
- 18:49to worry too much about alright and
- 18:53that's it for developmental conditions I
- 18:55hope you enjoyed this video if you like
- 18:58what I do on this channel make sure to
- 19:00leave a like and subscribe for more oral
- 19:02pathology and other things dentistry
- 19:04thanks for watching guys and I'll see
- 19:06you all next time
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