New Collagen Human Study Shows Skin Age Reversal! — Transcript

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1. 0:00A new human study shows that collagen
2. 0:02supplements significantly reduce
3. 0:03wrinkles around the eyes after only 12
4. 0:06weeks of treatment. Let's dive into the
5. 0:08details of the study to see if we can
6. 0:10rely on the result. And at the end of
7. 0:11the video, I'll share with you how this
8. 0:13changes what I do with collagen
9. 0:15supplements. The paper starts by
10. 0:17outlining that ultraviolet radiation
11. 0:18exposure from the sun stimulates the
12. 0:20inflammatory response and oxidative
13. 0:22stress in human skin, resulting in the
14. 0:24degradation of collagen. So, collagen is
15. 0:27quite a ropy structure. It keeps
16. 0:29everything together. And this breakdown
17. 0:30of collagen results in fine to deep
18. 0:33wrinkles, also known as skin aging. Now,
19. 0:35several experiments and randomized
20. 0:37controlled trials have been conducted
21. 0:39over the last two decades to determine
22. 0:41the impact of collagen supplements on
23. 0:43skin health. For example, we've got this
24. 0:45meta-analysis that combined 10 separate
25. 0:48clinical studies. And the evidence from
26. 0:50these studies shows that oral
27. 0:52supplements of collagen, they
28. 0:53significantly improve skin health.
29. 0:55However, many of the existing clinical
30. 0:57trials have failed to explain the
31. 0:59underlying mechanisms in depth.
32. 1:01Therefore, it is necessary to conduct a
33. 1:03series of studies to cohesively address
34. 1:06the mechanisms of action for the
35. 1:07efficacy and safety in humans. The
36. 1:10authors hypothesized that
37. 1:11supplementation of low molecular weight
38. 1:13collagen peptides could improve skin
39. 1:15aging by providing a scaffold for the
40. 1:18collagen repair and regrowth. So, let's
41. 1:20just go back a step for a moment.
42. 1:22Collagen are long ropy structures, and
43. 1:24our body will struggle to absorb those
44. 1:26ropy structures as a supplement. So,
45. 1:28collagen peptides are where those long
46. 1:30chains of collagen are chopped up into
47. 1:32smaller pieces or peptides. Those
48. 1:34peptides can then be absorbed. Now, for
49. 1:36this study, they looked at low molecular
50. 1:39weight collagen peptides. What that
51. 1:40means is very small chains of collagen
52. 1:43peptides instead of slightly longer
53. 1:44ones. So, this study is a randomized
54. 1:46controlled study on facial aging in
55. 1:48Asian skin after 12 weeks of
56. 1:50supplementation with low molecular
57. 1:52weight collagen peptides. That's
58. 1:54important. All participants were
59. 1:56randomly assigned to either take the
60. 1:58collagen peptides or a placebo in a
61. 2:00one-to-one ratio. One tablet had 500 mg
62. 2:04of the collagen peptides, and the
63. 2:05participants, they took two tablets
64. 2:08twice a day. Now, when doing a skin
65. 2:10study like this, it's important that we
66. 2:12have objective outcomes. So, what I mean
67. 2:14by this is that we don't just simply
68. 2:16want to look at the skin with the human
69. 2:17eye to make a judgement as to whether
70. 2:19the collagen peptides are going to work
71. 2:21or not. Ideally, we want photos taken
72. 2:23and those photos to be objectively
73. 2:25measured by a computer system. And
74. 2:27that's exactly what we see in this
75. 2:28study, where the authors, they measured
76. 2:30the wrinkles around the eyes by using a
77. 2:32three-dimensional measuring method. In
78. 2:34addition, two separate dermatologists,
79. 2:37who didn't know who was in which group,
80. 2:39independently evaluated the wrinkles
81. 2:41around the eyes to make sure that we've
82. 2:43got another objective measurement. A
83. 2:45total of 84 people completed the study,
84. 2:47and before the study began, there were
85. 2:49no significant differences between the
86. 2:51two groups. So, we are comparing apples
87. 2:53to apples. And before we get into the
88. 2:55results, we've now got over 150 patrons
89. 2:58who are accelerating their own longevity
90. 3:00journey and supporting the rapamycin
91. 3:02clinical study. So, thank you all so
92. 3:04much for your support. And if you do
93. 3:06want to check out this program, make
94. 3:07sure to check out the card in the corner
95. 3:09or the link in the pinned comment. The
96. 3:11authors found that the group who were
97. 3:12taking the collagen supplements, they
98. 3:14had significantly reduced wrinkles
99. 3:15around the eyes, and this reached
100. 3:18statistical significance. This is
101. 3:20incredibly exciting. We can actually see
102. 3:22reversal of wrinkles around the eyes by
103. 3:24using collagen supplements. Furthermore,
104. 3:27the collagen supplements were well
105. 3:28tolerated, and there was no reports of
106. 3:30severe adverse events. Now, this paper
107. 3:33is interesting because it focused on low
108. 3:35molecular weight collagen peptides. So,
109. 3:37remember, this is where the collagen is
110. 3:39chopped into very short chains. And the
111. 3:41authors say that they wanted to focus on
112. 3:43the low molecular weight collagen
113. 3:44peptides because the high molecular
114. 3:46weight collagen peptides, they decompose
115. 3:48in the stomach quickly and do not reach
116. 3:50the skin. The paper finishes by
117. 3:52concluding that in this randomized
118. 3:54placebo-controlled clinical trial, it
119. 3:56suggests that low molecular weight
120. 3:58collagen peptides effectively improve
121. 4:00photo-aged and dry skin while showing a
122. 4:03favorable safety profile. The current
123. 4:05collagen supplements that I use is from
124. 4:07a company called Do Not Age, but I don't
125. 4:09know if this is a low molecular weight
126. 4:11collagen supplement. So, I'll reach out
127. 4:13to Do Not Age, and as soon as I hear
128. 4:15back from them, I'll update the pinned
129. 4:17comment. The other thing I'll mention is
130. 4:19that this study it used a very low dose,
131. 4:21so only 1 g twice a day. Now, the dose
132. 4:24that I take is between 10 to 15 g every
133. 4:27day. Personally, I'll still be using
134. 4:29that higher dose, but it will be
135. 4:30interesting for further studies to
136. 4:32evaluate whether there is a dose
137. 4:34response, whether we will be seeing
138. 4:36further benefits for our skin by taking
139. 4:38that higher dose, or whether we can save
140. 4:40our money by taking a lower dose. Time
141. 4:42will tell. And while we can see from the
142. 4:44study that collagen supplements do seem
143. 4:46to have incredible benefits for our
144. 4:48skin, make sure to check out this next
145. 4:50video here on other strategies that we
146. 4:52can use to protect our skin and look
147. 4:54younger than our age. A massive thank
148. 4:56you to donotage.org for the $10,000
149. 4:59donation to my rapamycin study. They are
150. 5:01a health research organization, and to
151. 5:03benefit from their ingredients as well
152. 5:05as a 10% discount code, check out the
153. 5:07pinned comment.