YouTube2Text

Lo que nadie te dice sobre el colágeno (Estudios científicos) — Transcript

by La Traumatóloga Geek · 5,122 words · 779 segments · language en · Watch on YouTube

Full transcript

  1. 0:00There’s a jar in your bathroom, your
  2. 0:02kitchen, or your mother’s purse—
  3. 0:04white, elegant, with gold lettering. It
  4. 0:07says collagen. Maybe it says marine
  5. 0:10collagen. Maybe it says with hyaluronic
  6. 0:13acid and a hint of vanilla. It cost you
  7. 0:15between 20 and 40 euros, and you take
  8. 0:18it every morning, convinced you're
  9. 0:20giving your skin, your joints, even
  10. 0:22your bones, exactly what they’re
  11. 0:24running out of. I’m going to tell you
  12. 0:26something you’re not going to like.
  13. 0:28That powder you’re taking is
  14. 0:30chemically the same as gelatin in a
  15. 0:32dessert. The same as the film on your
  16. 0:35grandma's stew broth when it cools down
  17. 0:37and gets jiggly. Exactly the same
  18. 0:40molecule. The only difference between a
  19. 0:4230-euro jar and a packet of neutral
  20. 0:44gelatin from the supermarket is
  21. 0:46marketing. Strawberry flavoring and a
  22. 0:49photo of a 60-year-old woman with the
  23. 0:51skin of a 30-year-old. "But Inés, it
  24. 0:54works for me.""I notice my skin is
  25. 0:56better.""My knees hurt less." And here
  26. 0:58is where it gets interesting. You might
  27. 1:00be right. It might not be a total lie.
  28. 1:03There are good, serious studies,
  29. 1:05published in real journals, that
  30. 1:07suggest it does do something—a little
  31. 1:09, but something. The thing is, it does
  32. 1:12it for a completely different reason
  33. 1:14than what they’ve sold you, and when
  34. 1:16you understand the real reason,
  35. 1:18you’ll look at that jar differently
  36. 1:20and probably stop paying 30 euros for
  37. 1:22what you can get for one, because this
  38. 1:24isn’t new. This has happened before.
  39. 1:28In Paris in 1841, with a commission of
  40. 1:30Europe's most important scientists. A
  41. 1:34bone-boiling machine and a pack of dogs
  42. 1:36that starved to death with bellies full
  43. 1:38of collagen. By the end of this video,
  44. 1:41you will see three things. You’ll
  45. 1:43know what really happens to collagen
  46. 1:45when you swallow it. You’ll know what
  47. 1:47the only good studies that exist
  48. 1:49actually say and why they have a huge
  49. 1:51asterisk next to them, and you’ll
  50. 1:54know exactly what to do to make your
  51. 1:56own collagen without any brand taking
  52. 1:58your money. I’m Doctor Inés. Welcome
  53. 2:01to my channel. I’ve spent over 11
  54. 2:03years putting my hands inside the human
  55. 2:05body—knees, hips, shoulders, tendons.
  56. 2:10I’ve seen real collagen, the kind
  57. 2:12inside that holds up your skeleton—
  58. 2:14not the one in the jar—live, shiny,
  59. 2:16white, taut, or frayed like an old rope
  60. 2:18. And I’ll tell you one thing right
  61. 2:22now: collagen is probably the most
  62. 2:23important protein in your body, and the
  63. 2:25one you’ve never been told the truth
  64. 2:27about. It is the scaffolding for
  65. 2:30everything: for skin, bone, cartilage,
  66. 2:33tendons, your artery walls, your gums,
  67. 2:35and the corneas of your eyes. If it
  68. 2:38were to disappear suddenly, you would
  69. 2:40collapse onto the floor like a puddle
  70. 2:42of gelatin. Collagen literally holds
  71. 2:44you together. So the question isn't
  72. 2:47silly, it's actually a very good one.
  73. 2:49If collagen is so important and we
  74. 2:52produce less of it as we age, why not
  75. 2:54just take it directly? It sounds
  76. 2:57logical, it even sounds elegant. So,
  77. 2:59today we are going to answer three
  78. 3:01questions. The first: what really
  79. 3:04happens to collagen when you swallow it
  80. 3:06? Because I’ll tell you right now,
  81. 3:08your gut isn't foolish enough to let
  82. 3:10the whole protein pass through and send
  83. 3:12it straight to your face. What it does
  84. 3:14is something else, and that something
  85. 3:16changes everything. The second: does it
  86. 3:19actually work, or is it just a trick?
  87. 3:21I’m going to show you the solid
  88. 3:23studies, with names, numbers, and
  89. 3:25dosages. And I’m also going to show
  90. 3:27you who funded them, which is something
  91. 3:29you should always look at in nutrition.
  92. 3:31And the third, the one that’s going
  93. 3:32to make you the angriest. Why does
  94. 3:35something that biology gives away for
  95. 3:37free cost you 30 euros? Stay until the
  96. 3:41end, because when I show you what your
  97. 3:43body truly needs to produce collagen,
  98. 3:46you’ll realize you’ve been paying
  99. 3:48for half the recipe, while the other
  100. 3:50half—the part that really matters—
  101. 3:52is in your fridge for pennies. It turns
  102. 3:56out that in the early 19th century,
  103. 3:59France had a massive problem. Parisian
  104. 4:02hospitals were full of the poor, the
  105. 4:05sick, and orphans. There was nothing to
  106. 4:08feed them with. Meat was extremely
  107. 4:10expensive, and someone came up with an
  108. 4:12idea that looked brilliant on paper. If
  109. 4:15meat is expensive, let’s use the
  110. 4:17bones that get thrown away. You can
  111. 4:19extract gelatin from bones. Gelatin is
  112. 4:21protein. Let’s give gelatin to the
  113. 4:24poor and feed them for free. An 1841
  114. 4:27report from the Academy of Sciences,
  115. 4:30signed by some of the best scientists
  116. 4:33of the era, was, word for word, the
  117. 4:36answer to today’s collagen fad; only
  118. 4:39it was written 180 years ago, with dogs
  119. 4:42, steam engines, and a level of rigor
  120. 4:45that many Instagram experts would kill
  121. 4:48for. We are in Paris, in the 1830s. The
  122. 4:52city smells of coal, horses, and hunger
  123. 4:55. There is a man named Jean Pierre
  124. 4:58Joseph Darcet. He is a chemist, the son
  125. 5:01of a chemist. He is a man of the
  126. 5:03Enlightenment, the kind who believes
  127. 5:05with all his soul that science can
  128. 5:07solve the people's problems. And
  129. 5:10d’Arcet has an obsession: to end
  130. 5:12hunger for the poor in Paris by using
  131. 5:14something the city throws away by the
  132. 5:17ton—bones—because Paris generates
  133. 5:19mountains of bones every day from
  134. 5:21butcher shops, slaughterhouses, and
  135. 5:23kitchens. And d’Arcet knows something
  136. 5:26that normal people don’t: that inside
  137. 5:29the bone, besides calcium, there is a
  138. 5:31substance that, when boiled for a long
  139. 5:33time, becomes a thick liquid that
  140. 5:35wobbles when it cools. Gelatin, the
  141. 5:38same thing carpenters used to glue wood
  142. 5:41: boiled collagen. D’Arcet thinks: "
  143. 5:44This is protein, this nourishes," and
  144. 5:47he designs machines, autoclaves,
  145. 5:49pressure bone-boilers that extract
  146. 5:52gelatin on an industrial scale. He
  147. 5:55installs them in Paris hospitals, at
  148. 5:58the Hôtel-Dieu, at La Pitié, and
  149. 6:00begins boiling gelatin soup for the
  150. 6:02sick, the convalescents, and the poor.
  151. 6:05At first, everyone applauds. It’s
  152. 6:08cheap, it’s abundant, the plate
  153. 6:10wobbles, it looks like rich people’s
  154. 6:12food, and it’s pure protein. Or so
  155. 6:14they think? And don’t think this was
  156. 6:16just the whim of a few crazy people.
  157. 6:18This was taken seriously at the highest
  158. 6:20level. Factories were set up, contracts
  159. 6:23were signed with hospices, with prisons
  160. 6:26, with the city's charities. They
  161. 6:29proudly calculated how many thousands
  162. 6:31of rations they could get from the
  163. 6:34bones Paris threw away every week.
  164. 6:37People were convinced they were about
  165. 6:40to end the hunger of the poor in one of
  166. 6:42Europe’s largest cities by recycling
  167. 6:45trash. It was, for the mentality of the
  168. 6:48time, a humanitarian and scientific
  169. 6:51revolution at once. Gelatin was the
  170. 6:54superfood of the future. A future
  171. 6:56fueled by what used to rot in the
  172. 6:58street. Look at how seductive, how
  173. 7:01logical, and how similar this is to
  174. 7:03what makes you put a jar in your cart
  175. 7:06today. It’s protein, it comes from
  176. 7:09bone, it’s what we need. Take it
  177. 7:11directly. The exact same logic, 200
  178. 7:15years apart. But something strange
  179. 7:18starts to happen. Hospital doctors
  180. 7:20begin to notice that patients eating a
  181. 7:22lot of gelatin aren't getting better.
  182. 7:26What’s more, some get worse, they
  183. 7:27feel weak, they don’t heal; they eat
  184. 7:30it, they get full, they stop being
  185. 7:31hungry for a while, and yet they just
  186. 7:34wither away. As if eating were doing
  187. 7:37them no good at all. And this is where
  188. 7:39the story gets serious, because in
  189. 7:42France, when there is a real scientific
  190. 7:44dispute, they call in the heavy cavalry
  191. 7:47, the Academy of Science, the same home
  192. 7:49of Lavoisier, of Laplace, of the greats
  193. 7:52; they create an official commission,
  194. 7:54and they call it, without any
  195. 7:56imagination, the Gelatin Commission.
  196. 7:59And at the head of it, they put a man
  197. 8:01who did not mess around. His name is
  198. 8:04François Magendie, a physiologist, one
  199. 8:06of the fathers of experimental medicine
  200. 8:09. The teacher of Claude Bernard, a cold
  201. 8:11, rigorous man who didn't believe in
  202. 8:14anything that couldn't be measured.
  203. 8:16Magendie was the type who thought that
  204. 8:19an opinion without an experiment is
  205. 8:21worth nothing, and he set out to
  206. 8:22experiment. The commission took years.
  207. 8:26At a certain point, someone from the
  208. 8:28academy grew impatient and asked them
  209. 8:30for the report. Magendie, who by then
  210. 8:32was presiding over the house, replied
  211. 8:34that the experiments were still
  212. 8:36underway and that he wouldn't turn
  213. 8:37anything in until he was sure. It took
  214. 8:40them 7 years. And here I want you to
  215. 8:42understand why this is so important,
  216. 8:44beyond the anecdote. We are talking
  217. 8:47about the birth of an idea that seems
  218. 8:49obvious to us today, but was
  219. 8:51revolutionary back then. That to know
  220. 8:54if a food is useful, it’s not enough
  221. 8:56to reason about it; you have to test it
  222. 8:58, measure it, and compare it with
  223. 9:00control groups. Magendie was one of the
  224. 9:04first to apply this to food, and he
  225. 9:07applied it precisely with gelatin
  226. 9:09because he sensed that Darcet's neat
  227. 9:11logic might be completely wrong—that
  228. 9:13"it is protein, therefore it nourishes"
  229. 9:16was a tricky syllogism, and to
  230. 9:18dismantle it, he didn't argue, he
  231. 9:20experimented. And what was Magendie
  232. 9:23doing during those 7 years? Dogs,
  233. 9:25hundreds of dogs. And controlled,
  234. 9:28weighed, measured food. In an era when
  235. 9:31nobody did that. He took dogs and
  236. 9:33divided them into groups. To one, he
  237. 9:35gave only gelatin. The purest gelatin,
  238. 9:39the best extracted, the one Darcet
  239. 9:41defended. Water and gelatin, as much as
  240. 9:44they wanted. And the dogs died. They
  241. 9:48died just like the dogs that were given
  242. 9:50absolutely nothing at all. What's more,
  243. 9:53at first, the dogs ate the gelatin
  244. 9:55eagerly. A few days later, they would
  245. 9:57sniff it and turn away as if their
  246. 9:59bodies knew something the commission
  247. 10:01didn't yet know. They preferred to eat
  248. 10:03nothing rather than eat only that, and
  249. 10:05they died in the same timeframe as if
  250. 10:07they had been left to fast. Magendie
  251. 10:10tried everything. Gelatin alone,
  252. 10:13gelatin with a bit of fat, gelatin with
  253. 10:15a bit of meat to make it appetizing. It
  254. 10:18didn't matter. If the basis of the diet
  255. 10:20was gelatin, the dog would fade away.
  256. 10:23And then he did the experiment that
  257. 10:25closed it all out. He took another
  258. 10:28group of dogs and gave them a mixed,
  259. 10:30varied, normal diet. Those dogs were
  260. 10:34perfect, healthy, strong, with shiny
  261. 10:37coats. And to top it off, the report
  262. 10:40says he fed one group for months with
  263. 10:43raw bones, real bones, with their
  264. 10:46marrow, cartilage, fat, everything. And
  265. 10:49those dogs eating whole bones remained
  266. 10:52strong and vigorous. Do you see? The
  267. 10:55whole bone, good. Gelatin alone, death.
  268. 10:59On August 2, 1841, Magendie took the
  269. 11:03podium at the Paris Academy of Sciences
  270. 11:06and read the Gelatin Commission's
  271. 11:09report. And the verdict was devastating
  272. 11:11. Gelatin on its own does not nourish,
  273. 11:14does not sustain life, does not replace
  274. 11:17meat. A body that only receives gelatin
  275. 11:20dies. No more machines for the poor. No
  276. 11:23more bone soup for the poor. The dream
  277. 11:26of feeding Paris with what was being
  278. 11:28thrown away was over. The Academy had
  279. 11:30spoken. Now then, why does the same
  280. 11:33material that forms your bones, skin,
  281. 11:35and tendons not serve to nourish you if
  282. 11:38you take it purified? Magendie did not
  283. 11:41have the molecular answer. He couldn't
  284. 11:44have it because amino acids weren't
  285. 11:46fully discovered until decades later,
  286. 11:48but he sensed the essential point: that
  287. 11:50gelatin, although it is protein, is an
  288. 11:52incomplete protein. It is missing
  289. 11:55something, and that something turned
  290. 11:57out to be an essential amino acid
  291. 11:59called tryptophan. In other words,
  292. 12:02collagen has no tryptophan, and without
  293. 12:05tryptophan, your body cannot rebuild
  294. 12:08the proteins it needs to live. It
  295. 12:10doesn't matter how much you eat. And
  296. 12:12here is what blows my mind. Today's
  297. 12:15collagen industry sells you exactly
  298. 12:17what Magendie proved does not nourish.
  299. 12:20The same material, the same molecule,
  300. 12:22hydrolyzed gelatin, which is nothing
  301. 12:24more than gelatin broken into smaller
  302. 12:27pieces. The commission of the best
  303. 12:30scientists in Europe spent 7 years
  304. 12:32proving that, on its own, it doesn't do
  305. 12:35what it promises, and 180 years later,
  306. 12:38the same thing in strawberry-flavored
  307. 12:40powder is sold as the elixir of eternal
  308. 12:43youth. History does not repeat itself,
  309. 12:46but it rhymes, and that rhyme costs €
  310. 12:4830 a jar. The science behind it. Okay,
  311. 12:50let's look at the body, because there
  312. 12:52is a nuance here that is extremely
  313. 12:53important and that almost no one
  314. 12:55explains well—neither those who sell
  315. 12:57you collagen, nor those who tell you
  316. 12:59it's a total scam. The truth, as almost
  317. 13:01always, is in the middle and is much
  318. 13:04more interesting. First, let's
  319. 13:06understand what collagen is when it's
  320. 13:08inside you. Imagine the reinforced
  321. 13:10concrete of a building. Concrete can
  322. 13:13hold weight, but what keeps it from
  323. 13:15cracking and crumbling are the steel
  324. 13:17bars inside, the ones you can't see in
  325. 13:19your body. Those bars are collagen. It
  326. 13:22is a rope-shaped protein. Three long,
  327. 13:26braided strands, resistant to tension.
  328. 13:30There are 28 different types, but the
  329. 13:32one in charge, which accounts for 90%,
  330. 13:35is type 1 collagen. It is in the bone,
  331. 13:38in the tendon, and in the skin. And
  332. 13:41there is one more thing they will try
  333. 13:42to sell you, and it's worth knowing
  334. 13:44about these types of collagen. You will
  335. 13:47see jars that say type 1 and 3 collagen
  336. 13:50for skin, type 2 for joints, as if it
  337. 13:52were a targeted medicine, like a key
  338. 13:55fitting into a perfect lock. That is
  339. 13:58pure nonsense, because as we will see
  340. 14:00now, you don't absorb type 2 collagen
  341. 14:02and send it to your joints, or type 1
  342. 14:04to your skin; you break it all down
  343. 14:06equally in your gut, and the
  344. 14:08distinction is gone. The type on the
  345. 14:10label is a marketing trick that
  346. 14:12exploits the fact that types of
  347. 14:14collagen really do exist in your body
  348. 14:16to make you believe the powder knows
  349. 14:18where to go. It doesn't know. No
  350. 14:20protein you eat knows where to go. And
  351. 14:23now, the fact that changes everything.
  352. 14:25Collagen is not a statue. It is a
  353. 14:27permanent construction site. Your body
  354. 14:29is continuously destroying and
  355. 14:31rebuilding it every single day of your
  356. 14:33life, like a crew of masons removing
  357. 14:35old bricks and laying new ones non-stop
  358. 14:38. When you are young, the crew is huge
  359. 14:40and works fast. From the age of 25 or
  360. 14:43so, you begin to lose the ability to
  361. 14:45produce collagen by about 1%every year.
  362. 14:49When a woman reaches menopause and her
  363. 14:51estrogen levels drop, that loss
  364. 14:53accelerates. Up to 30%of skin collagen
  365. 14:57can be lost in the first 5 years after
  366. 15:00menopause. That is why skin thins and
  367. 15:03wrinkles, and why bones become fragile.
  368. 15:07It is not just calcium; the collagen
  369. 15:09scaffolding where the calcium attaches
  370. 15:12is crumbling. Up to this point,
  371. 15:14everything supports the logic of the
  372. 15:15jar. If I lose it, I replenish it. But
  373. 15:18here, the intestine enters the picture
  374. 15:19and complicates everything. When you
  375. 15:21take that collagen, your body doesn't
  376. 15:22just grab it and stick it on. That is
  377. 15:24impossible. Your intestine does not let
  378. 15:27whole proteins pass into your
  379. 15:28bloodstream. If it did, you would have
  380. 15:30a brutal allergic reaction every time
  381. 15:32you ate. What your digestive system
  382. 15:35does is what it does with any protein,
  383. 15:37with a steak or an egg. It tears it
  384. 15:40apart, breaking it down into individual
  385. 15:42bricks, the amino acids, or into small
  386. 15:44pieces of two or three bricks, the
  387. 15:45peptides. In other words, you take
  388. 15:48collagen from a cow or a fish, it turns
  389. 15:51it into a bunch of loose pieces that
  390. 15:53are identical to those any other
  391. 15:55protein would give you, and your face
  392. 15:57doesn't receive that collagen; it
  393. 16:00receives a handful of amino acids that
  394. 16:02your own body decides how to use based
  395. 16:04on its own rules. It might build a
  396. 16:07muscle, it might make a protein, or
  397. 16:09with any luck, it might make a little
  398. 16:11bit of collagen wherever it feels like.
  399. 16:15It’s as if you bought a very
  400. 16:16expensive designer piece of furniture,
  401. 16:18put it through a shredder at your front
  402. 16:20door, and expected the resulting
  403. 16:22sawdust to reassemble itself into the
  404. 16:24original piece of furniture inside your
  405. 16:26living room. That’s not how it works.
  406. 16:28The shredder is your stomach, and it
  407. 16:30doesn't care if the furniture was from
  408. 16:31IKEA or a luxury brand. Now, a fair
  409. 16:34caveat, because I don't want to feed
  410. 16:36you a tall tale on the other side
  411. 16:39either. It turns out that not all
  412. 16:41collagen is broken down completely into
  413. 16:43loose bricks. A small portion survives
  414. 16:47as two-amino-acid pieces, specific
  415. 16:49peptides with names like
  416. 16:51proline-hydroxyproline. And it has been
  417. 16:55observed that these bits do reach the
  418. 16:58blood, do circulate, and could act not
  419. 17:00as building material, but as a kind of
  420. 17:02signal, like a message, as if those
  421. 17:05fragments floating in your blood were
  422. 17:07telling your cells: "Hey, collagen is
  423. 17:09being broken down somewhere." Start
  424. 17:13building—a useful false alarm, let's
  425. 17:16say. "It was shown that
  426. 17:19hydroxyproline-containing peptides,
  427. 17:22such as prolyl-hydroxyproline and
  428. 17:24glycyl-prolyl-hydroxyproline, are
  429. 17:27stable in gastrointestinal fluid, are
  430. 17:29absorbed, and reach higher plasma
  431. 17:32concentrations after oral
  432. 17:34administration, suggesting that the
  433. 17:36intake of collagen tripeptide is an
  434. 17:39effective way to provide bioactive
  435. 17:41peptides orally." Son Tak, Journal of
  436. 17:46Agricultural and Food Chemistry 2016.
  437. 17:50In other words, the idea is not
  438. 17:52absolute nonsense; there is a plausible
  439. 17:55biological pathway, but look closely at
  440. 17:57what it doesn't say. It doesn't say it
  441. 18:01replenishes your collagen; it says some
  442. 18:03fragments reach the blood and could
  443. 18:05send a signal. From "could send a
  444. 18:09signal in a lab model" to "it takes
  445. 18:11years off your face." There is a small
  446. 18:14commercial chasm, and there is one more
  447. 18:16thing, the most important of all, and
  448. 18:18it's what Magendie didn't get to see.
  449. 18:20For your body to actually make real
  450. 18:23collagen, it needs an essential tool, a
  451. 18:25vitamin. Without it, you have all the
  452. 18:28bricks in the world and you can't build
  453. 18:30anything. That vitamin is vitamin C,
  454. 18:33and that is what the next part is about
  455. 18:35because it has one of the most
  456. 18:37terrifying stories in medicine behind
  457. 18:39it. Heavy artillery data. But before
  458. 18:42vitamin C, I owe you the numbers
  459. 18:43because I said there are good studies,
  460. 18:45and I’m going to give them to you
  461. 18:46straight, and then I’ll give you the
  462. 18:48asterisk. Data point one, the skin.
  463. 18:50Study by Proksch et al. published in
  464. 18:54Skin Pharmacology and Physiology in
  465. 18:562014. 69 women between 35 and 54 years
  466. 19:01old. Double-blind with placebo, as it
  467. 19:04should be. Some took 2.5 g of collagen
  468. 19:08peptides daily, others 5 g, others a
  469. 19:10placebo, for 8 weeks. The result: those
  470. 19:14who took collagen improved skin
  471. 19:17elasticity in a statistically
  472. 19:19significant way compared to the placebo
  473. 19:22. In other words, it wasn't a
  474. 19:24coincidence; the skin was objectively
  475. 19:27more elastic, measured with devices,
  476. 19:30not just "I look better." Data point
  477. 19:33two, the joints. Study by Clark et al.
  478. 19:36published in Current Medical Research
  479. 19:39and Opinion in 2008. Conducted at Penn
  480. 19:42State University. 147 college athletes
  481. 19:46with joint pain from exercise. 10 g of
  482. 19:49hydrolyzed collagen daily versus
  483. 19:51placebo. 24 weeks. Result: the collagen
  484. 19:56group had significantly less joint pain
  485. 19:58when walking, standing, or lifting
  486. 20:00weight. And for those who had knee pain
  487. 20:04, specifically, the effect was even
  488. 20:06clearer. Data point three, and this is
  489. 20:09the one that really interests me as an
  490. 20:10orthopedist. Bone. Study by König et
  491. 20:13al. published in the journal Nutrients
  492. 20:16in 2018. 131 postmenopausal women with
  493. 20:21already low bone density, 5 g of
  494. 20:23specific collagen peptides daily or
  495. 20:25placebo for a whole year, double-blind,
  496. 20:28and they measured bone mineral density
  497. 20:31of the spine and femoral neck, which is
  498. 20:34where it really matters, where grandma
  499. 20:37breaks her hip. After 12 months, the
  500. 20:40bone mineral density of the spine and
  501. 20:43femoral neck increased significantly in
  502. 20:45the group that took collagen peptides
  503. 20:48compared to the placebo group. In
  504. 20:51addition, a favorable shift in bone
  505. 20:54markers was observed, indicating
  506. 20:56greater bone formation and less
  507. 20:58degradation. König et al. Nutrients
  508. 21:012018.
  509. 21:02This is serious. It is exactly what an
  510. 21:04orthopedist looks for. A simple, cheap
  511. 21:07intervention. Safe, and one that
  512. 21:09improves bone density a little for
  513. 21:12women who are losing it. A little, mind
  514. 21:14you, it is not a drug, it does not
  515. 21:16replace bisphosphonates, but it adds up
  516. 21:18, and when something adds up, costs
  517. 21:20little, and does no harm. Data point
  518. 21:22four, so you can see that I don't side
  519. 21:24with those who criticize it either. The
  520. 21:26John et al. study, published in the
  521. 21:28Journal of Medical Food in 2014,
  522. 21:30involved 45 people taking hydrolyzed
  523. 21:33collagen combined with astaxanthin, an
  524. 21:35antioxidant. 12 weeks. It improved
  525. 21:39facial skin elasticity, and this is
  526. 21:41what's interesting: it reduced the
  527. 21:43expression of enzymes called
  528. 21:44metalloproteinases, which are literally
  529. 21:46the scissors that break down your
  530. 21:48cartilage. In other words, there was a
  531. 21:52biological signal, not just a sensation
  532. 21:54—again, a real, modest effect with an
  533. 21:56antioxidant helping, not just the
  534. 21:58collagen. So, I know what you're
  535. 22:01thinking. Are you telling me, Inés,
  536. 22:04that after all that talk about
  537. 22:05Magendie's dogs, collagen actually
  538. 22:07works? Well, be careful, because here
  539. 22:10comes the asterisk, and it's a big one.
  540. 22:14First, look at the dosages. 2.5, 5, 10
  541. 22:17grams a day, every day for months, not
  542. 22:20a little shot every now and then. If
  543. 22:23you're taking half a teaspoon three
  544. 22:25times a week and expecting a miracle,
  545. 22:27forget it. Second, and this is the big
  546. 22:30one: who funds these studies? Because
  547. 22:33in the bone study, one of the authors
  548. 22:36is from the Collagen Research Institute
  549. 22:39—a place literally named the Collagen
  550. 22:42Research Institute—and in the skin
  551. 22:45study, a name linked to the collagen
  552. 22:48industry appears again. This doesn't
  553. 22:51mean the studies are fake or rigged.
  554. 22:54They are methodologically sound studies
  555. 22:56published in peer-reviewed journals,
  556. 22:59but when the manufacturer is among
  557. 23:01those researching the product, caution
  558. 23:03dictates taking the results with a
  559. 23:06grain of salt. We must wait for
  560. 23:09independent researchers to replicate
  561. 23:11them and be wary of the most
  562. 23:13enthusiastic conclusions. And I tell
  563. 23:16you this from experience, because in
  564. 23:17medicine, we see this constantly and
  565. 23:19have learned how to read it. When a
  566. 23:23study with positive results is funded
  567. 23:25by the person selling the product, we
  568. 23:27don't throw it in the trash, but we
  569. 23:29apply what we call the "interest
  570. 23:31discount." It's like when a salesman
  571. 23:34tells you a car is wonderful. Maybe
  572. 23:36it's true, but you internally lower the
  573. 23:38enthusiasm a bit because you know they
  574. 23:40make money if you believe them. It's
  575. 23:42the same with collagen. Most of the
  576. 23:44nice research comes directly or
  577. 23:46indirectly from the very sector that
  578. 23:49markets it. And the funny thing is that
  579. 23:52they don't even need to lie. It’s
  580. 23:54enough to choose which studies get
  581. 23:56published and which ones get tucked
  582. 23:57away in a drawer. By measuring the
  583. 23:59parameter that turns out well and not
  584. 24:00the one that turns out average. It's
  585. 24:02not fraud; it's gardening. It's pruning
  586. 24:05the data until the shrub has the shape
  587. 24:07that sells. That’s why, until there
  588. 24:10are large, long-term studies paid for
  589. 24:12by someone with no stake in the outcome
  590. 24:15, I’ll keep my enthusiasm in check.
  591. 24:18And the third, the final asterisk—the
  592. 24:20one that stings. There is not a single
  593. 24:24large, long-term, independent study
  594. 24:26showing that taking collagen makes you
  595. 24:29age slower, live longer, or prevents a
  596. 24:32single real hip fracture. What exists
  597. 24:35are small improvements in specific
  598. 24:37parameters, measured over very short
  599. 24:40periods, and sometimes by people with
  600. 24:42an interest in the result. Now, the
  601. 24:44brutal truth. The molecule in your €
  602. 24:4830 tub and the one in a € 1 packet of
  603. 24:50unflavored gelatin are the same—
  604. 24:53identical. Hydrolyzed collagen. Yes,
  605. 24:56the effect is real. You can get it for
  606. 24:59€ 1; you’re paying € 29 for the
  607. 25:01packaging and the flavor. Because while
  608. 25:04science moves slowly with its small
  609. 25:06trials and studies of 70 women, the
  610. 25:08industry has done what it always does.
  611. 25:13It took a molecule with a real but
  612. 25:15modest effect, put it in a pretty jar,
  613. 25:17hiked the price 20-fold, and sold you a
  614. 25:19story that biology doesn't support.
  615. 25:22Let’s break down the tub, ingredient
  616. 25:24by ingredient. "Marine collagen" sounds
  617. 25:26like it’s from the bottom of the
  618. 25:27ocean. Like seaweed; it’s actually
  619. 25:30just boiled fish skin and scales.
  620. 25:33Nothing wrong with that, but it’s
  621. 25:34exactly the same. It's hydrolyzed
  622. 25:36collagen from cows or pigs, it just
  623. 25:38sounds more expensive, so they charge
  624. 25:40you more for it. The word "marine"
  625. 25:42gives you nothing; it just takes money
  626. 25:44from your pocket. Strawberry or vanilla
  627. 25:46flavored? Turn the tub around and read
  628. 25:48the label. Often, the second or third
  629. 25:50ingredient is sugar. Sometimes
  630. 25:53sweeteners, sometimes straight-up sugar
  631. 25:55. In other words, to take your "
  632. 25:57anti-aging" protein, you’re consuming
  633. 25:59sugar, which is precisely one of the
  634. 26:02things that damages collagen the most
  635. 26:04through a process called glycation. You
  636. 26:06give with one hand and take away with
  637. 26:08the other. This is the best one. "With
  638. 26:10hyaluronic acid, coenzyme Q10, and 12
  639. 26:12vitamins." The oldest trick in the book
  640. 26:14: they add a little bit of everything
  641. 26:16to justify the price. Often in
  642. 26:18ridiculous amounts, far below what
  643. 26:20would actually be useful, but they look
  644. 26:22great on the label. And now the crown
  645. 26:24jewel, the ultimate perversion: many
  646. 26:27collagen tubs have added vitamin C, and
  647. 26:29they tout it as an extra, a gift— "
  648. 26:32look how complete our product is." Well
  649. 26:34, it turns out that this "extra" is
  650. 26:36likely the only thing actually doing
  651. 26:37anything at all. And this brings us
  652. 26:39back to what I left you hanging with
  653. 26:41earlier. Do you remember me saying your
  654. 26:44body needs a vitamin to produce
  655. 26:46collagen? It's vitamin C. Without it,
  656. 26:49the enzymes won't braid. The three
  657. 26:51strands of collagen don't work, and
  658. 26:53that's not theory. It has a name and
  659. 26:56one of the most hair-raising histories
  660. 26:58at sea: scurvy. For centuries, sailors
  661. 27:01would go months without fresh fruit,
  662. 27:03develop scurvy, and it is nothing more
  663. 27:06and nothing less than your body
  664. 27:08stopping the production of collagen.
  665. 27:10And what happens when you stop building
  666. 27:12the scaffolding for everything? Well,
  667. 27:14the most terrifying part: their teeth
  668. 27:16would fall out because gums are pure
  669. 27:19collagen, they would bleed everywhere
  670. 27:21because blood vessel walls are collagen
  671. 27:23, and, most chilling of all, old wounds
  672. 27:26would reopen; scars from 20 years ago
  673. 27:28from a youthful fight, from a childhood
  674. 27:31surgery, would open on their own, and
  675. 27:33fractures that had healed decades
  676. 27:36earlier would separate again. Why?
  677. 27:38Because, as I told you, collagen is not
  678. 27:40a statue; it’s a permanent
  679. 27:41construction site. Your body is
  680. 27:43constantly making and unmaking your
  681. 27:46scars and your bones. As long as there
  682. 27:48is vitamin C, the crew replaces what it
  683. 27:50removes. When the vitamin runs out, the
  684. 27:52crew keeps removing, but they can't
  685. 27:54replace anything. And everything that
  686. 27:56was once built with collagen falls
  687. 27:58apart. And here is the connection that
  688. 28:00nobody tells you about when they sell
  689. 28:02you the jar. Human beings, along with
  690. 28:04primates and a few other critters, are
  691. 28:07the only animals on the planet that
  692. 28:09have lost the ability to produce our
  693. 28:11own vitamin C. Most animals produce it
  694. 28:13in their liver. A dog doesn't get
  695. 28:16scurvy from not eating oranges. We do.
  696. 28:19At some point in our evolution, the
  697. 28:21gene that produces it broke, and since
  698. 28:23we ate plenty of fruit, nothing
  699. 28:25happened. We became dependent on the
  700. 28:28outside for the only tool with which we
  701. 28:30build our body's scaffolding. In that
  702. 28:32sense, we are more fragile than our own
  703. 28:35dog. And the latest perversion, the
  704. 28:37most expensive of all: capsules,
  705. 28:39collagen in pill form, because at least
  706. 28:41the powder gives you a dose of several
  707. 28:43grams. But for collagen to do the
  708. 28:46little that studies show it can do, you
  709. 28:49need between 5 and 10 grams a day. Do
  710. 28:52you know how much collagen fits in a
  711. 28:54capsule? One gram, if you're lucky. So,
  712. 28:57to reach the dosage from the studies,
  713. 28:59you would have to take about 20 pills a
  714. 29:02day. You take two because the bottle
  715. 29:04says so, and those two pills give you a
  716. 29:06ridiculous dose that hasn't proven
  717. 29:08anything in any serious study, but the
  718. 29:10bottle is tiny, fits in your purse, is
  719. 29:12recommended by an influencer with a
  720. 29:14discount code, and costs the same or
  721. 29:16more than the powder. You are paying
  722. 29:19the maximum price for a minimum dose.
  723. 29:21It is the worst deal on the whole shelf
  724. 29:23and it sells the most because it is the
  725. 29:24most convenient. So pay attention to
  726. 29:27the cosmic joke. They sell you a $ 30
  727. 29:29tub of collagen, but for it to work,
  728. 29:31they have to add vitamin C, which costs
  729. 29:33pennies, and that is what actually gets
  730. 29:36your body to produce its own collagen.
  731. 29:39If you eat enough animal protein—eggs
  732. 29:41, chicken, fish, legumes—and enough
  733. 29:43vitamin C—a kiwi, a bell pepper, an
  734. 29:45orange—your body has everything it
  735. 29:47needs to manufacture its own collagen
  736. 29:49for free, with the building blocks you
  737. 29:51want and where you want them. Okay, I
  738. 29:54know what you’re thinking again,
  739. 29:56Inés. So, should I take the collagen
  740. 29:58or not? And my answer is clear: if you
  741. 30:00have money to spare and you’re
  742. 30:02excited about it, take it. It won’t
  743. 30:04hurt you, and it might give you that
  744. 30:06modest little boost the studies talk
  745. 30:07about. But if you're on a budget, save
  746. 30:10the money on the tub, buy a $ 1 packet
  747. 30:12of unflavored gelatin if you want the
  748. 30:14same collagen, or even better, invest
  749. 30:17that money in real protein, in fruit
  750. 30:19and vegetables with vitamin C. It is
  751. 30:21the only thing that has proven beyond
  752. 30:23any doubt, with no brand behind it,
  753. 30:25that it produces massive amounts of
  754. 30:27collagen and bone. Moving your body.
  755. 30:31Bone and tendon grow collagen when you
  756. 30:33use them. That doesn’t come in any
  757. 30:35tub and no one can sell it to you. The
  758. 30:38question I want to leave you with today
  759. 30:40is: how many of the things you take for
  760. 30:42your health are bets on biology, and
  761. 30:44how many are bets on marketing? The
  762. 30:48collagen in your tub is not a scam, but
  763. 30:50it’s not magic either; it’s a
  764. 30:52modest molecule with a massive
  765. 30:53advertising campaign, and you are
  766. 30:55paying the difference between what it
  767. 30:56costs and what it does. What you can do
  768. 30:59tomorrow is very simple. Pick up your
  769. 31:02tub of collagen, turn it over, read the
  770. 31:04ingredients, look for the sugar, look
  771. 31:06for the vitamin C, and ask yourself if
  772. 31:08you are paying $ 30 for a bit of
  773. 31:10gelatin and a spoonful of sugar. If you
  774. 31:14really want new collagen today for free
  775. 31:16, get up and make your muscles and
  776. 31:18bones pull something heavy. That is the
  777. 31:22recipe no brand wants you to know
  778. 31:24because it cannot be bottled. I am Dr.
  779. 31:26In. See you on the next shift.

About this transcript

This page contains the full transcript of Lo que nadie te dice sobre el colágeno (Estudios científicos) by La Traumatóloga Geek, generated from the public captions YouTube serves with the video. The transcript has 5,122 words across 779 segments, with the original timestamps preserved so you can click any line to jump to that moment in the embedded player.

What you can do with it

Use the transcript to take notes, quote the speaker, build a study guide, generate a summary with ChatGPT or Claude via the YouTube Summary tool, or export it as a timed subtitle file with YouTube to SRT. You can also re-open it in the transcriber to translate the transcript into 100+ languages.

Free YouTube transcript tool

YouTube2Text is a free YouTube transcript generator — no signup, no daily limit. Paste any YouTube link and get the full transcript instantly, with timestamps, click-to-jump, translation to 100+ languages, AI prompts for ChatGPT, Claude, and Gemini, and exports to TXT, SRT, VTT, or Markdown.