Lo que nadie te dice sobre el colágeno (Estudios científicos) — Transcript
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- 0:00There’s a jar in your bathroom, your
- 0:02kitchen, or your mother’s purse—
- 0:04white, elegant, with gold lettering. It
- 0:07says collagen. Maybe it says marine
- 0:10collagen. Maybe it says with hyaluronic
- 0:13acid and a hint of vanilla. It cost you
- 0:15between 20 and 40 euros, and you take
- 0:18it every morning, convinced you're
- 0:20giving your skin, your joints, even
- 0:22your bones, exactly what they’re
- 0:24running out of. I’m going to tell you
- 0:26something you’re not going to like.
- 0:28That powder you’re taking is
- 0:30chemically the same as gelatin in a
- 0:32dessert. The same as the film on your
- 0:35grandma's stew broth when it cools down
- 0:37and gets jiggly. Exactly the same
- 0:40molecule. The only difference between a
- 0:4230-euro jar and a packet of neutral
- 0:44gelatin from the supermarket is
- 0:46marketing. Strawberry flavoring and a
- 0:49photo of a 60-year-old woman with the
- 0:51skin of a 30-year-old. "But Inés, it
- 0:54works for me.""I notice my skin is
- 0:56better.""My knees hurt less." And here
- 0:58is where it gets interesting. You might
- 1:00be right. It might not be a total lie.
- 1:03There are good, serious studies,
- 1:05published in real journals, that
- 1:07suggest it does do something—a little
- 1:09, but something. The thing is, it does
- 1:12it for a completely different reason
- 1:14than what they’ve sold you, and when
- 1:16you understand the real reason,
- 1:18you’ll look at that jar differently
- 1:20and probably stop paying 30 euros for
- 1:22what you can get for one, because this
- 1:24isn’t new. This has happened before.
- 1:28In Paris in 1841, with a commission of
- 1:30Europe's most important scientists. A
- 1:34bone-boiling machine and a pack of dogs
- 1:36that starved to death with bellies full
- 1:38of collagen. By the end of this video,
- 1:41you will see three things. You’ll
- 1:43know what really happens to collagen
- 1:45when you swallow it. You’ll know what
- 1:47the only good studies that exist
- 1:49actually say and why they have a huge
- 1:51asterisk next to them, and you’ll
- 1:54know exactly what to do to make your
- 1:56own collagen without any brand taking
- 1:58your money. I’m Doctor Inés. Welcome
- 2:01to my channel. I’ve spent over 11
- 2:03years putting my hands inside the human
- 2:05body—knees, hips, shoulders, tendons.
- 2:10I’ve seen real collagen, the kind
- 2:12inside that holds up your skeleton—
- 2:14not the one in the jar—live, shiny,
- 2:16white, taut, or frayed like an old rope
- 2:18. And I’ll tell you one thing right
- 2:22now: collagen is probably the most
- 2:23important protein in your body, and the
- 2:25one you’ve never been told the truth
- 2:27about. It is the scaffolding for
- 2:30everything: for skin, bone, cartilage,
- 2:33tendons, your artery walls, your gums,
- 2:35and the corneas of your eyes. If it
- 2:38were to disappear suddenly, you would
- 2:40collapse onto the floor like a puddle
- 2:42of gelatin. Collagen literally holds
- 2:44you together. So the question isn't
- 2:47silly, it's actually a very good one.
- 2:49If collagen is so important and we
- 2:52produce less of it as we age, why not
- 2:54just take it directly? It sounds
- 2:57logical, it even sounds elegant. So,
- 2:59today we are going to answer three
- 3:01questions. The first: what really
- 3:04happens to collagen when you swallow it
- 3:06? Because I’ll tell you right now,
- 3:08your gut isn't foolish enough to let
- 3:10the whole protein pass through and send
- 3:12it straight to your face. What it does
- 3:14is something else, and that something
- 3:16changes everything. The second: does it
- 3:19actually work, or is it just a trick?
- 3:21I’m going to show you the solid
- 3:23studies, with names, numbers, and
- 3:25dosages. And I’m also going to show
- 3:27you who funded them, which is something
- 3:29you should always look at in nutrition.
- 3:31And the third, the one that’s going
- 3:32to make you the angriest. Why does
- 3:35something that biology gives away for
- 3:37free cost you 30 euros? Stay until the
- 3:41end, because when I show you what your
- 3:43body truly needs to produce collagen,
- 3:46you’ll realize you’ve been paying
- 3:48for half the recipe, while the other
- 3:50half—the part that really matters—
- 3:52is in your fridge for pennies. It turns
- 3:56out that in the early 19th century,
- 3:59France had a massive problem. Parisian
- 4:02hospitals were full of the poor, the
- 4:05sick, and orphans. There was nothing to
- 4:08feed them with. Meat was extremely
- 4:10expensive, and someone came up with an
- 4:12idea that looked brilliant on paper. If
- 4:15meat is expensive, let’s use the
- 4:17bones that get thrown away. You can
- 4:19extract gelatin from bones. Gelatin is
- 4:21protein. Let’s give gelatin to the
- 4:24poor and feed them for free. An 1841
- 4:27report from the Academy of Sciences,
- 4:30signed by some of the best scientists
- 4:33of the era, was, word for word, the
- 4:36answer to today’s collagen fad; only
- 4:39it was written 180 years ago, with dogs
- 4:42, steam engines, and a level of rigor
- 4:45that many Instagram experts would kill
- 4:48for. We are in Paris, in the 1830s. The
- 4:52city smells of coal, horses, and hunger
- 4:55. There is a man named Jean Pierre
- 4:58Joseph Darcet. He is a chemist, the son
- 5:01of a chemist. He is a man of the
- 5:03Enlightenment, the kind who believes
- 5:05with all his soul that science can
- 5:07solve the people's problems. And
- 5:10d’Arcet has an obsession: to end
- 5:12hunger for the poor in Paris by using
- 5:14something the city throws away by the
- 5:17ton—bones—because Paris generates
- 5:19mountains of bones every day from
- 5:21butcher shops, slaughterhouses, and
- 5:23kitchens. And d’Arcet knows something
- 5:26that normal people don’t: that inside
- 5:29the bone, besides calcium, there is a
- 5:31substance that, when boiled for a long
- 5:33time, becomes a thick liquid that
- 5:35wobbles when it cools. Gelatin, the
- 5:38same thing carpenters used to glue wood
- 5:41: boiled collagen. D’Arcet thinks: "
- 5:44This is protein, this nourishes," and
- 5:47he designs machines, autoclaves,
- 5:49pressure bone-boilers that extract
- 5:52gelatin on an industrial scale. He
- 5:55installs them in Paris hospitals, at
- 5:58the Hôtel-Dieu, at La Pitié, and
- 6:00begins boiling gelatin soup for the
- 6:02sick, the convalescents, and the poor.
- 6:05At first, everyone applauds. It’s
- 6:08cheap, it’s abundant, the plate
- 6:10wobbles, it looks like rich people’s
- 6:12food, and it’s pure protein. Or so
- 6:14they think? And don’t think this was
- 6:16just the whim of a few crazy people.
- 6:18This was taken seriously at the highest
- 6:20level. Factories were set up, contracts
- 6:23were signed with hospices, with prisons
- 6:26, with the city's charities. They
- 6:29proudly calculated how many thousands
- 6:31of rations they could get from the
- 6:34bones Paris threw away every week.
- 6:37People were convinced they were about
- 6:40to end the hunger of the poor in one of
- 6:42Europe’s largest cities by recycling
- 6:45trash. It was, for the mentality of the
- 6:48time, a humanitarian and scientific
- 6:51revolution at once. Gelatin was the
- 6:54superfood of the future. A future
- 6:56fueled by what used to rot in the
- 6:58street. Look at how seductive, how
- 7:01logical, and how similar this is to
- 7:03what makes you put a jar in your cart
- 7:06today. It’s protein, it comes from
- 7:09bone, it’s what we need. Take it
- 7:11directly. The exact same logic, 200
- 7:15years apart. But something strange
- 7:18starts to happen. Hospital doctors
- 7:20begin to notice that patients eating a
- 7:22lot of gelatin aren't getting better.
- 7:26What’s more, some get worse, they
- 7:27feel weak, they don’t heal; they eat
- 7:30it, they get full, they stop being
- 7:31hungry for a while, and yet they just
- 7:34wither away. As if eating were doing
- 7:37them no good at all. And this is where
- 7:39the story gets serious, because in
- 7:42France, when there is a real scientific
- 7:44dispute, they call in the heavy cavalry
- 7:47, the Academy of Science, the same home
- 7:49of Lavoisier, of Laplace, of the greats
- 7:52; they create an official commission,
- 7:54and they call it, without any
- 7:56imagination, the Gelatin Commission.
- 7:59And at the head of it, they put a man
- 8:01who did not mess around. His name is
- 8:04François Magendie, a physiologist, one
- 8:06of the fathers of experimental medicine
- 8:09. The teacher of Claude Bernard, a cold
- 8:11, rigorous man who didn't believe in
- 8:14anything that couldn't be measured.
- 8:16Magendie was the type who thought that
- 8:19an opinion without an experiment is
- 8:21worth nothing, and he set out to
- 8:22experiment. The commission took years.
- 8:26At a certain point, someone from the
- 8:28academy grew impatient and asked them
- 8:30for the report. Magendie, who by then
- 8:32was presiding over the house, replied
- 8:34that the experiments were still
- 8:36underway and that he wouldn't turn
- 8:37anything in until he was sure. It took
- 8:40them 7 years. And here I want you to
- 8:42understand why this is so important,
- 8:44beyond the anecdote. We are talking
- 8:47about the birth of an idea that seems
- 8:49obvious to us today, but was
- 8:51revolutionary back then. That to know
- 8:54if a food is useful, it’s not enough
- 8:56to reason about it; you have to test it
- 8:58, measure it, and compare it with
- 9:00control groups. Magendie was one of the
- 9:04first to apply this to food, and he
- 9:07applied it precisely with gelatin
- 9:09because he sensed that Darcet's neat
- 9:11logic might be completely wrong—that
- 9:13"it is protein, therefore it nourishes"
- 9:16was a tricky syllogism, and to
- 9:18dismantle it, he didn't argue, he
- 9:20experimented. And what was Magendie
- 9:23doing during those 7 years? Dogs,
- 9:25hundreds of dogs. And controlled,
- 9:28weighed, measured food. In an era when
- 9:31nobody did that. He took dogs and
- 9:33divided them into groups. To one, he
- 9:35gave only gelatin. The purest gelatin,
- 9:39the best extracted, the one Darcet
- 9:41defended. Water and gelatin, as much as
- 9:44they wanted. And the dogs died. They
- 9:48died just like the dogs that were given
- 9:50absolutely nothing at all. What's more,
- 9:53at first, the dogs ate the gelatin
- 9:55eagerly. A few days later, they would
- 9:57sniff it and turn away as if their
- 9:59bodies knew something the commission
- 10:01didn't yet know. They preferred to eat
- 10:03nothing rather than eat only that, and
- 10:05they died in the same timeframe as if
- 10:07they had been left to fast. Magendie
- 10:10tried everything. Gelatin alone,
- 10:13gelatin with a bit of fat, gelatin with
- 10:15a bit of meat to make it appetizing. It
- 10:18didn't matter. If the basis of the diet
- 10:20was gelatin, the dog would fade away.
- 10:23And then he did the experiment that
- 10:25closed it all out. He took another
- 10:28group of dogs and gave them a mixed,
- 10:30varied, normal diet. Those dogs were
- 10:34perfect, healthy, strong, with shiny
- 10:37coats. And to top it off, the report
- 10:40says he fed one group for months with
- 10:43raw bones, real bones, with their
- 10:46marrow, cartilage, fat, everything. And
- 10:49those dogs eating whole bones remained
- 10:52strong and vigorous. Do you see? The
- 10:55whole bone, good. Gelatin alone, death.
- 10:59On August 2, 1841, Magendie took the
- 11:03podium at the Paris Academy of Sciences
- 11:06and read the Gelatin Commission's
- 11:09report. And the verdict was devastating
- 11:11. Gelatin on its own does not nourish,
- 11:14does not sustain life, does not replace
- 11:17meat. A body that only receives gelatin
- 11:20dies. No more machines for the poor. No
- 11:23more bone soup for the poor. The dream
- 11:26of feeding Paris with what was being
- 11:28thrown away was over. The Academy had
- 11:30spoken. Now then, why does the same
- 11:33material that forms your bones, skin,
- 11:35and tendons not serve to nourish you if
- 11:38you take it purified? Magendie did not
- 11:41have the molecular answer. He couldn't
- 11:44have it because amino acids weren't
- 11:46fully discovered until decades later,
- 11:48but he sensed the essential point: that
- 11:50gelatin, although it is protein, is an
- 11:52incomplete protein. It is missing
- 11:55something, and that something turned
- 11:57out to be an essential amino acid
- 11:59called tryptophan. In other words,
- 12:02collagen has no tryptophan, and without
- 12:05tryptophan, your body cannot rebuild
- 12:08the proteins it needs to live. It
- 12:10doesn't matter how much you eat. And
- 12:12here is what blows my mind. Today's
- 12:15collagen industry sells you exactly
- 12:17what Magendie proved does not nourish.
- 12:20The same material, the same molecule,
- 12:22hydrolyzed gelatin, which is nothing
- 12:24more than gelatin broken into smaller
- 12:27pieces. The commission of the best
- 12:30scientists in Europe spent 7 years
- 12:32proving that, on its own, it doesn't do
- 12:35what it promises, and 180 years later,
- 12:38the same thing in strawberry-flavored
- 12:40powder is sold as the elixir of eternal
- 12:43youth. History does not repeat itself,
- 12:46but it rhymes, and that rhyme costs €
- 12:4830 a jar. The science behind it. Okay,
- 12:50let's look at the body, because there
- 12:52is a nuance here that is extremely
- 12:53important and that almost no one
- 12:55explains well—neither those who sell
- 12:57you collagen, nor those who tell you
- 12:59it's a total scam. The truth, as almost
- 13:01always, is in the middle and is much
- 13:04more interesting. First, let's
- 13:06understand what collagen is when it's
- 13:08inside you. Imagine the reinforced
- 13:10concrete of a building. Concrete can
- 13:13hold weight, but what keeps it from
- 13:15cracking and crumbling are the steel
- 13:17bars inside, the ones you can't see in
- 13:19your body. Those bars are collagen. It
- 13:22is a rope-shaped protein. Three long,
- 13:26braided strands, resistant to tension.
- 13:30There are 28 different types, but the
- 13:32one in charge, which accounts for 90%,
- 13:35is type 1 collagen. It is in the bone,
- 13:38in the tendon, and in the skin. And
- 13:41there is one more thing they will try
- 13:42to sell you, and it's worth knowing
- 13:44about these types of collagen. You will
- 13:47see jars that say type 1 and 3 collagen
- 13:50for skin, type 2 for joints, as if it
- 13:52were a targeted medicine, like a key
- 13:55fitting into a perfect lock. That is
- 13:58pure nonsense, because as we will see
- 14:00now, you don't absorb type 2 collagen
- 14:02and send it to your joints, or type 1
- 14:04to your skin; you break it all down
- 14:06equally in your gut, and the
- 14:08distinction is gone. The type on the
- 14:10label is a marketing trick that
- 14:12exploits the fact that types of
- 14:14collagen really do exist in your body
- 14:16to make you believe the powder knows
- 14:18where to go. It doesn't know. No
- 14:20protein you eat knows where to go. And
- 14:23now, the fact that changes everything.
- 14:25Collagen is not a statue. It is a
- 14:27permanent construction site. Your body
- 14:29is continuously destroying and
- 14:31rebuilding it every single day of your
- 14:33life, like a crew of masons removing
- 14:35old bricks and laying new ones non-stop
- 14:38. When you are young, the crew is huge
- 14:40and works fast. From the age of 25 or
- 14:43so, you begin to lose the ability to
- 14:45produce collagen by about 1%every year.
- 14:49When a woman reaches menopause and her
- 14:51estrogen levels drop, that loss
- 14:53accelerates. Up to 30%of skin collagen
- 14:57can be lost in the first 5 years after
- 15:00menopause. That is why skin thins and
- 15:03wrinkles, and why bones become fragile.
- 15:07It is not just calcium; the collagen
- 15:09scaffolding where the calcium attaches
- 15:12is crumbling. Up to this point,
- 15:14everything supports the logic of the
- 15:15jar. If I lose it, I replenish it. But
- 15:18here, the intestine enters the picture
- 15:19and complicates everything. When you
- 15:21take that collagen, your body doesn't
- 15:22just grab it and stick it on. That is
- 15:24impossible. Your intestine does not let
- 15:27whole proteins pass into your
- 15:28bloodstream. If it did, you would have
- 15:30a brutal allergic reaction every time
- 15:32you ate. What your digestive system
- 15:35does is what it does with any protein,
- 15:37with a steak or an egg. It tears it
- 15:40apart, breaking it down into individual
- 15:42bricks, the amino acids, or into small
- 15:44pieces of two or three bricks, the
- 15:45peptides. In other words, you take
- 15:48collagen from a cow or a fish, it turns
- 15:51it into a bunch of loose pieces that
- 15:53are identical to those any other
- 15:55protein would give you, and your face
- 15:57doesn't receive that collagen; it
- 16:00receives a handful of amino acids that
- 16:02your own body decides how to use based
- 16:04on its own rules. It might build a
- 16:07muscle, it might make a protein, or
- 16:09with any luck, it might make a little
- 16:11bit of collagen wherever it feels like.
- 16:15It’s as if you bought a very
- 16:16expensive designer piece of furniture,
- 16:18put it through a shredder at your front
- 16:20door, and expected the resulting
- 16:22sawdust to reassemble itself into the
- 16:24original piece of furniture inside your
- 16:26living room. That’s not how it works.
- 16:28The shredder is your stomach, and it
- 16:30doesn't care if the furniture was from
- 16:31IKEA or a luxury brand. Now, a fair
- 16:34caveat, because I don't want to feed
- 16:36you a tall tale on the other side
- 16:39either. It turns out that not all
- 16:41collagen is broken down completely into
- 16:43loose bricks. A small portion survives
- 16:47as two-amino-acid pieces, specific
- 16:49peptides with names like
- 16:51proline-hydroxyproline. And it has been
- 16:55observed that these bits do reach the
- 16:58blood, do circulate, and could act not
- 17:00as building material, but as a kind of
- 17:02signal, like a message, as if those
- 17:05fragments floating in your blood were
- 17:07telling your cells: "Hey, collagen is
- 17:09being broken down somewhere." Start
- 17:13building—a useful false alarm, let's
- 17:16say. "It was shown that
- 17:19hydroxyproline-containing peptides,
- 17:22such as prolyl-hydroxyproline and
- 17:24glycyl-prolyl-hydroxyproline, are
- 17:27stable in gastrointestinal fluid, are
- 17:29absorbed, and reach higher plasma
- 17:32concentrations after oral
- 17:34administration, suggesting that the
- 17:36intake of collagen tripeptide is an
- 17:39effective way to provide bioactive
- 17:41peptides orally." Son Tak, Journal of
- 17:46Agricultural and Food Chemistry 2016.
- 17:50In other words, the idea is not
- 17:52absolute nonsense; there is a plausible
- 17:55biological pathway, but look closely at
- 17:57what it doesn't say. It doesn't say it
- 18:01replenishes your collagen; it says some
- 18:03fragments reach the blood and could
- 18:05send a signal. From "could send a
- 18:09signal in a lab model" to "it takes
- 18:11years off your face." There is a small
- 18:14commercial chasm, and there is one more
- 18:16thing, the most important of all, and
- 18:18it's what Magendie didn't get to see.
- 18:20For your body to actually make real
- 18:23collagen, it needs an essential tool, a
- 18:25vitamin. Without it, you have all the
- 18:28bricks in the world and you can't build
- 18:30anything. That vitamin is vitamin C,
- 18:33and that is what the next part is about
- 18:35because it has one of the most
- 18:37terrifying stories in medicine behind
- 18:39it. Heavy artillery data. But before
- 18:42vitamin C, I owe you the numbers
- 18:43because I said there are good studies,
- 18:45and I’m going to give them to you
- 18:46straight, and then I’ll give you the
- 18:48asterisk. Data point one, the skin.
- 18:50Study by Proksch et al. published in
- 18:54Skin Pharmacology and Physiology in
- 18:562014. 69 women between 35 and 54 years
- 19:01old. Double-blind with placebo, as it
- 19:04should be. Some took 2.5 g of collagen
- 19:08peptides daily, others 5 g, others a
- 19:10placebo, for 8 weeks. The result: those
- 19:14who took collagen improved skin
- 19:17elasticity in a statistically
- 19:19significant way compared to the placebo
- 19:22. In other words, it wasn't a
- 19:24coincidence; the skin was objectively
- 19:27more elastic, measured with devices,
- 19:30not just "I look better." Data point
- 19:33two, the joints. Study by Clark et al.
- 19:36published in Current Medical Research
- 19:39and Opinion in 2008. Conducted at Penn
- 19:42State University. 147 college athletes
- 19:46with joint pain from exercise. 10 g of
- 19:49hydrolyzed collagen daily versus
- 19:51placebo. 24 weeks. Result: the collagen
- 19:56group had significantly less joint pain
- 19:58when walking, standing, or lifting
- 20:00weight. And for those who had knee pain
- 20:04, specifically, the effect was even
- 20:06clearer. Data point three, and this is
- 20:09the one that really interests me as an
- 20:10orthopedist. Bone. Study by König et
- 20:13al. published in the journal Nutrients
- 20:16in 2018. 131 postmenopausal women with
- 20:21already low bone density, 5 g of
- 20:23specific collagen peptides daily or
- 20:25placebo for a whole year, double-blind,
- 20:28and they measured bone mineral density
- 20:31of the spine and femoral neck, which is
- 20:34where it really matters, where grandma
- 20:37breaks her hip. After 12 months, the
- 20:40bone mineral density of the spine and
- 20:43femoral neck increased significantly in
- 20:45the group that took collagen peptides
- 20:48compared to the placebo group. In
- 20:51addition, a favorable shift in bone
- 20:54markers was observed, indicating
- 20:56greater bone formation and less
- 20:58degradation. König et al. Nutrients
- 21:012018.
- 21:02This is serious. It is exactly what an
- 21:04orthopedist looks for. A simple, cheap
- 21:07intervention. Safe, and one that
- 21:09improves bone density a little for
- 21:12women who are losing it. A little, mind
- 21:14you, it is not a drug, it does not
- 21:16replace bisphosphonates, but it adds up
- 21:18, and when something adds up, costs
- 21:20little, and does no harm. Data point
- 21:22four, so you can see that I don't side
- 21:24with those who criticize it either. The
- 21:26John et al. study, published in the
- 21:28Journal of Medical Food in 2014,
- 21:30involved 45 people taking hydrolyzed
- 21:33collagen combined with astaxanthin, an
- 21:35antioxidant. 12 weeks. It improved
- 21:39facial skin elasticity, and this is
- 21:41what's interesting: it reduced the
- 21:43expression of enzymes called
- 21:44metalloproteinases, which are literally
- 21:46the scissors that break down your
- 21:48cartilage. In other words, there was a
- 21:52biological signal, not just a sensation
- 21:54—again, a real, modest effect with an
- 21:56antioxidant helping, not just the
- 21:58collagen. So, I know what you're
- 22:01thinking. Are you telling me, Inés,
- 22:04that after all that talk about
- 22:05Magendie's dogs, collagen actually
- 22:07works? Well, be careful, because here
- 22:10comes the asterisk, and it's a big one.
- 22:14First, look at the dosages. 2.5, 5, 10
- 22:17grams a day, every day for months, not
- 22:20a little shot every now and then. If
- 22:23you're taking half a teaspoon three
- 22:25times a week and expecting a miracle,
- 22:27forget it. Second, and this is the big
- 22:30one: who funds these studies? Because
- 22:33in the bone study, one of the authors
- 22:36is from the Collagen Research Institute
- 22:39—a place literally named the Collagen
- 22:42Research Institute—and in the skin
- 22:45study, a name linked to the collagen
- 22:48industry appears again. This doesn't
- 22:51mean the studies are fake or rigged.
- 22:54They are methodologically sound studies
- 22:56published in peer-reviewed journals,
- 22:59but when the manufacturer is among
- 23:01those researching the product, caution
- 23:03dictates taking the results with a
- 23:06grain of salt. We must wait for
- 23:09independent researchers to replicate
- 23:11them and be wary of the most
- 23:13enthusiastic conclusions. And I tell
- 23:16you this from experience, because in
- 23:17medicine, we see this constantly and
- 23:19have learned how to read it. When a
- 23:23study with positive results is funded
- 23:25by the person selling the product, we
- 23:27don't throw it in the trash, but we
- 23:29apply what we call the "interest
- 23:31discount." It's like when a salesman
- 23:34tells you a car is wonderful. Maybe
- 23:36it's true, but you internally lower the
- 23:38enthusiasm a bit because you know they
- 23:40make money if you believe them. It's
- 23:42the same with collagen. Most of the
- 23:44nice research comes directly or
- 23:46indirectly from the very sector that
- 23:49markets it. And the funny thing is that
- 23:52they don't even need to lie. It’s
- 23:54enough to choose which studies get
- 23:56published and which ones get tucked
- 23:57away in a drawer. By measuring the
- 23:59parameter that turns out well and not
- 24:00the one that turns out average. It's
- 24:02not fraud; it's gardening. It's pruning
- 24:05the data until the shrub has the shape
- 24:07that sells. That’s why, until there
- 24:10are large, long-term studies paid for
- 24:12by someone with no stake in the outcome
- 24:15, I’ll keep my enthusiasm in check.
- 24:18And the third, the final asterisk—the
- 24:20one that stings. There is not a single
- 24:24large, long-term, independent study
- 24:26showing that taking collagen makes you
- 24:29age slower, live longer, or prevents a
- 24:32single real hip fracture. What exists
- 24:35are small improvements in specific
- 24:37parameters, measured over very short
- 24:40periods, and sometimes by people with
- 24:42an interest in the result. Now, the
- 24:44brutal truth. The molecule in your €
- 24:4830 tub and the one in a € 1 packet of
- 24:50unflavored gelatin are the same—
- 24:53identical. Hydrolyzed collagen. Yes,
- 24:56the effect is real. You can get it for
- 24:59€ 1; you’re paying € 29 for the
- 25:01packaging and the flavor. Because while
- 25:04science moves slowly with its small
- 25:06trials and studies of 70 women, the
- 25:08industry has done what it always does.
- 25:13It took a molecule with a real but
- 25:15modest effect, put it in a pretty jar,
- 25:17hiked the price 20-fold, and sold you a
- 25:19story that biology doesn't support.
- 25:22Let’s break down the tub, ingredient
- 25:24by ingredient. "Marine collagen" sounds
- 25:26like it’s from the bottom of the
- 25:27ocean. Like seaweed; it’s actually
- 25:30just boiled fish skin and scales.
- 25:33Nothing wrong with that, but it’s
- 25:34exactly the same. It's hydrolyzed
- 25:36collagen from cows or pigs, it just
- 25:38sounds more expensive, so they charge
- 25:40you more for it. The word "marine"
- 25:42gives you nothing; it just takes money
- 25:44from your pocket. Strawberry or vanilla
- 25:46flavored? Turn the tub around and read
- 25:48the label. Often, the second or third
- 25:50ingredient is sugar. Sometimes
- 25:53sweeteners, sometimes straight-up sugar
- 25:55. In other words, to take your "
- 25:57anti-aging" protein, you’re consuming
- 25:59sugar, which is precisely one of the
- 26:02things that damages collagen the most
- 26:04through a process called glycation. You
- 26:06give with one hand and take away with
- 26:08the other. This is the best one. "With
- 26:10hyaluronic acid, coenzyme Q10, and 12
- 26:12vitamins." The oldest trick in the book
- 26:14: they add a little bit of everything
- 26:16to justify the price. Often in
- 26:18ridiculous amounts, far below what
- 26:20would actually be useful, but they look
- 26:22great on the label. And now the crown
- 26:24jewel, the ultimate perversion: many
- 26:27collagen tubs have added vitamin C, and
- 26:29they tout it as an extra, a gift— "
- 26:32look how complete our product is." Well
- 26:34, it turns out that this "extra" is
- 26:36likely the only thing actually doing
- 26:37anything at all. And this brings us
- 26:39back to what I left you hanging with
- 26:41earlier. Do you remember me saying your
- 26:44body needs a vitamin to produce
- 26:46collagen? It's vitamin C. Without it,
- 26:49the enzymes won't braid. The three
- 26:51strands of collagen don't work, and
- 26:53that's not theory. It has a name and
- 26:56one of the most hair-raising histories
- 26:58at sea: scurvy. For centuries, sailors
- 27:01would go months without fresh fruit,
- 27:03develop scurvy, and it is nothing more
- 27:06and nothing less than your body
- 27:08stopping the production of collagen.
- 27:10And what happens when you stop building
- 27:12the scaffolding for everything? Well,
- 27:14the most terrifying part: their teeth
- 27:16would fall out because gums are pure
- 27:19collagen, they would bleed everywhere
- 27:21because blood vessel walls are collagen
- 27:23, and, most chilling of all, old wounds
- 27:26would reopen; scars from 20 years ago
- 27:28from a youthful fight, from a childhood
- 27:31surgery, would open on their own, and
- 27:33fractures that had healed decades
- 27:36earlier would separate again. Why?
- 27:38Because, as I told you, collagen is not
- 27:40a statue; it’s a permanent
- 27:41construction site. Your body is
- 27:43constantly making and unmaking your
- 27:46scars and your bones. As long as there
- 27:48is vitamin C, the crew replaces what it
- 27:50removes. When the vitamin runs out, the
- 27:52crew keeps removing, but they can't
- 27:54replace anything. And everything that
- 27:56was once built with collagen falls
- 27:58apart. And here is the connection that
- 28:00nobody tells you about when they sell
- 28:02you the jar. Human beings, along with
- 28:04primates and a few other critters, are
- 28:07the only animals on the planet that
- 28:09have lost the ability to produce our
- 28:11own vitamin C. Most animals produce it
- 28:13in their liver. A dog doesn't get
- 28:16scurvy from not eating oranges. We do.
- 28:19At some point in our evolution, the
- 28:21gene that produces it broke, and since
- 28:23we ate plenty of fruit, nothing
- 28:25happened. We became dependent on the
- 28:28outside for the only tool with which we
- 28:30build our body's scaffolding. In that
- 28:32sense, we are more fragile than our own
- 28:35dog. And the latest perversion, the
- 28:37most expensive of all: capsules,
- 28:39collagen in pill form, because at least
- 28:41the powder gives you a dose of several
- 28:43grams. But for collagen to do the
- 28:46little that studies show it can do, you
- 28:49need between 5 and 10 grams a day. Do
- 28:52you know how much collagen fits in a
- 28:54capsule? One gram, if you're lucky. So,
- 28:57to reach the dosage from the studies,
- 28:59you would have to take about 20 pills a
- 29:02day. You take two because the bottle
- 29:04says so, and those two pills give you a
- 29:06ridiculous dose that hasn't proven
- 29:08anything in any serious study, but the
- 29:10bottle is tiny, fits in your purse, is
- 29:12recommended by an influencer with a
- 29:14discount code, and costs the same or
- 29:16more than the powder. You are paying
- 29:19the maximum price for a minimum dose.
- 29:21It is the worst deal on the whole shelf
- 29:23and it sells the most because it is the
- 29:24most convenient. So pay attention to
- 29:27the cosmic joke. They sell you a $ 30
- 29:29tub of collagen, but for it to work,
- 29:31they have to add vitamin C, which costs
- 29:33pennies, and that is what actually gets
- 29:36your body to produce its own collagen.
- 29:39If you eat enough animal protein—eggs
- 29:41, chicken, fish, legumes—and enough
- 29:43vitamin C—a kiwi, a bell pepper, an
- 29:45orange—your body has everything it
- 29:47needs to manufacture its own collagen
- 29:49for free, with the building blocks you
- 29:51want and where you want them. Okay, I
- 29:54know what you’re thinking again,
- 29:56Inés. So, should I take the collagen
- 29:58or not? And my answer is clear: if you
- 30:00have money to spare and you’re
- 30:02excited about it, take it. It won’t
- 30:04hurt you, and it might give you that
- 30:06modest little boost the studies talk
- 30:07about. But if you're on a budget, save
- 30:10the money on the tub, buy a $ 1 packet
- 30:12of unflavored gelatin if you want the
- 30:14same collagen, or even better, invest
- 30:17that money in real protein, in fruit
- 30:19and vegetables with vitamin C. It is
- 30:21the only thing that has proven beyond
- 30:23any doubt, with no brand behind it,
- 30:25that it produces massive amounts of
- 30:27collagen and bone. Moving your body.
- 30:31Bone and tendon grow collagen when you
- 30:33use them. That doesn’t come in any
- 30:35tub and no one can sell it to you. The
- 30:38question I want to leave you with today
- 30:40is: how many of the things you take for
- 30:42your health are bets on biology, and
- 30:44how many are bets on marketing? The
- 30:48collagen in your tub is not a scam, but
- 30:50it’s not magic either; it’s a
- 30:52modest molecule with a massive
- 30:53advertising campaign, and you are
- 30:55paying the difference between what it
- 30:56costs and what it does. What you can do
- 30:59tomorrow is very simple. Pick up your
- 31:02tub of collagen, turn it over, read the
- 31:04ingredients, look for the sugar, look
- 31:06for the vitamin C, and ask yourself if
- 31:08you are paying $ 30 for a bit of
- 31:10gelatin and a spoonful of sugar. If you
- 31:14really want new collagen today for free
- 31:16, get up and make your muscles and
- 31:18bones pull something heavy. That is the
- 31:22recipe no brand wants you to know
- 31:24because it cannot be bottled. I am Dr.
- 31:26In. See you on the next shift.
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