Introduction to Chapter 3: Pharmacokinetics — Transcript

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1. 0:00hi there and welcome back so far we've
2. 0:03already started understanding some of
3. 0:05the principles of what we call
4. 0:07pharmacodynamics and simply put
5. 0:09pharmacodynamics means what the drug
6. 0:12does to the body basically how the drug
7. 0:15works in the body and with respect to
8. 0:19pharmacodynamics we've already taken a
9. 0:21look at a few medications that work by
10. 0:23direct action and we've also learned
11. 0:26that the majority of our medications
12. 0:28work on cellular receptors other as
13. 0:31agonists doing the same thing as the
14. 0:34natural substance would or as
15. 0:37antagonists going onto that receptor
16. 0:40blocking that receptor and preventing
17. 0:43our natural substances from binding onto
18. 0:47the receptor
19. 0:48and one of the goals in this chapter
20. 0:50will be to advance our knowledge of the
21. 0:53antagonists as we develop a really good
22. 0:56picture of the drug group that blocks
23. 0:58the histamine two receptors and since
24. 1:01the main drug group that we'll be
25. 1:03discussing needs to be absorbed into the
26. 1:05system in order to work we're going to
27. 1:07begin our discussions of
28. 1:09pharmacokinetics
29. 1:11and once again the first portion of that
30. 1:14means drug but the second portion of the
31. 1:16kinetics portion means movement so in
32. 1:20other words we're going to begin to
33. 1:22understand how our drugs move around the
34. 1:25body
35. 1:26what the body does to the drug
36. 1:30and when we're talking about
37. 1:31pharmacokinetics that'll involve four
38. 1:34distinct processes absorption
39. 1:37distribution metabolism and excretion
40. 1:41and while we are going to get a really
41. 1:43good picture of each one of the
42. 1:45processes that's pretty much our main
43. 1:47goal we're just going to need to picture
44. 1:50each one of the processes we don't need
45. 1:53to memorize very much at this point once
46. 1:56you've pictured each one of the
47. 1:57processes you can add to that picture as
48. 2:01you learn about specific drugs
49. 2:06just a real quick quiz here one of the
50. 2:09main things that we need to do in this
51. 2:11chapter is to get a really good picture
52. 2:13of absorption of drugs distribution of
53. 2:17drugs around the body metabolism of
54. 2:19drugs and the excretion of drugs the
55. 2:22branch of pharmacology that covers these
56. 2:25is called A
57. 2:27pharmacokinetics or B pharmacodynamics
58. 2:32and you are correct if you identified a
59. 2:35as the answer recall that pharmaco means
60. 2:38drug or poison and kinetics means
61. 2:41movement of so pharmacokinetics involves
62. 2:45the movement of drugs through the body
63. 2:46and includes the absorption distribution
64. 2:49metabolism and excretion think of
65. 2:53pharmacokinetics as being what the body
66. 2:55does to the drug basically the fate of
67. 2:59the drug in the system it's a really
68. 3:02interesting topic so let's jump straight
69. 3:04into it trying to picture these
70. 3:07processes