How To Reverse Skin Wrinkles (latest science) — Transcript
Full transcript
- 0:00we have the tools to reverse skin
- 0:02wrinkles and the signs of skin aging
- 0:04today this is not for vanity reasons how
- 0:06our skin looks reflects our chances of
- 0:09living a long life and if we see a young
- 0:11person in the mirror we're far more
- 0:13likely to identify as a young person and
- 0:15practice those healthy life habits so in
- 0:18addition to diet exercise and sleep the
- 0:21most important strategy is sunscreen and
- 0:23the only pushback that I've seen against
- 0:25sunscreen is safety which we'll cover
- 0:27shortly in a 2013 randomized trial
- 0:30involving over 900 adults the group who
- 0:32used daily sunscreen had no detectable
- 0:35increases in skin aging after four and a
- 0:37half years they essentially stopped
- 0:39their skin from aging just by using
- 0:42sunscreen and a follow-up 2016 paper
- 0:44showed the reversal of skin aging
- 0:46parameters but there are safety concerns
- 0:49about sunscreen so broadly speaking
- 0:51we've got mineral sunscreens and
- 0:53chemical sunscreens and some chemical
- 0:55sunscreen ingredients are absorbed into
- 0:57the bloodstream but it's important to
- 0:59note that as of 2023 there are no known
- 1:02Harms in humans from these ingredients
- 1:04being absorbed and the American Academy
- 1:06of Dermatology unambiguously states that
- 1:09sunscreen is safe to use nevertheless
- 1:12some people may elect to use mineral
- 1:14sunscreens because they are not absorbed
- 1:16but the downside is that they often
- 1:18don't protect against the Sun's UV
- 1:20radiation as well as chemical sunscreens
- 1:22and they can be difficult to apply now
- 1:24one mineral sunscreen are found to be
- 1:26quite good is from Elta MD but still
- 1:29it's not as good as a chemical based
- 1:31sunscreen particularly because we have a
- 1:33chemical ingredient called bimetrisinal
- 1:35which does protect against the different
- 1:37UV wavelengths but its best quality is
- 1:40its large size meaning that it doesn't
- 1:42get absorbed into the bloodstream and
- 1:44some brands that use bermatrisinal
- 1:46include Lara shape Posay and Nivea
- 1:49unfortunately though there is a problem
- 1:51even though we've known about
- 1:52bimetresinal since the 1990s it's still
- 1:55not FDA approved so bimetresenol is
- 1:58widely used in Europe and Australia Asia
- 2:00but it's not available in the USA and
- 2:02it's hoped that we would get approval
- 2:04for this in mid-2024. overall sunscreen
- 2:07is crucial for youthful looking skin and
- 2:10the current guidelines suggest that
- 2:12chemical sunscreens are safe personally
- 2:14I also supplement with a thousand units
- 2:16of vitamin D found in the multivitamin
- 2:18and mineral I take called microvitamin
- 2:21what we've dealt with is photo aging now
- 2:23we need to have a look at so-called
- 2:25normal aging where our collagen
- 2:27decreases by about 75 percent the great
- 2:30news is that we can rebuild our collagen
- 2:32ropes by supplementing with hydrolyzed
- 2:34collagen as evidenced by a 2020 review
- 2:37that included 10 separate randomized
- 2:40clinical trials all of the included
- 2:42studies included beneficial effects on
- 2:44skin Health parameters including
- 2:46moisture elasticity and wrinkle number
- 2:48plus there was a further 2022 randomized
- 2:51clinical trial again showing skin Health
- 2:53improvements with collagen peptides it
- 2:56reduced the wrinkles around the Eyes by
- 2:58eight percent collagen and peptides are
- 3:01short chains of amino acids and amino
- 3:03acids make up protein so one interesting
- 3:06question is whether collagen peptides
- 3:08offer any further benefits Beyond simply
- 3:10supplementing with protein to explore
- 3:12this a 2020 study of burn patients was
- 3:15done where one group was supplemented
- 3:17with protein and the other group
- 3:19supplemented with collagen peptides what
- 3:21they found is that the wound healing
- 3:23rate was significantly higher with the
- 3:25collagen peptides compared to protein I
- 3:28use 10 to 15 grams of collagen peptides
- 3:30every day now we want to step on the gas
- 3:33of the skin rebuilding process which is
- 3:35where retinal creams come in they
- 3:37stimulate the skin cells to produce
- 3:39collagen fibers and improve the skin
- 3:42blood supply we can see from a 2007
- 3:44randomized clinical trial where the
- 3:46group who used the retinal lotion had
- 3:49significant decreases in their wrinkle
- 3:50scores and many subsequent trials have
- 3:53confirmed the same thing when you start
- 3:55using retinol creams it does make your
- 3:57skin more sensitive so I strongly advise
- 3:59to use these creams at night and to
- 4:01always wear sunscreen during the day
- 4:03there are different versions of retinol
- 4:05creams and broadly speaking we've got
- 4:07adephalene and tretinoin in a large 2018
- 4:10trial both creams offered similar
- 4:12improvements in the signs of skin aging
- 4:14but adapaline has the advantage that
- 4:16it's less irritating to the skin
- 4:18personally I use tretinoin because
- 4:20that's the one available at the strength
- 4:22I want in New Zealand now that we've
- 4:24improved the blood supply to our skin
- 4:26the next component we want to rebuild is
- 4:28hyaluronic acid which also decreases as
- 4:31we age but just like collagen we can
- 4:33rebuild hyaluronic acid using
- 4:35supplements as evidenced by multiple
- 4:37randomized clinical trials including
- 4:39this one in 2021 showing an 18
- 4:42Improvement in wrinkle depth importantly
- 4:45that study was not sponsored by a
- 4:47supplement company now the only pushback
- 4:49I've seen against hyaluronic acid
- 4:51supplements is a concern about cancer
- 4:53but when hyaluronic acid was given to
- 4:55mice that already had cancer there were
- 4:57no changes in cancer growth I I take 200
- 5:00milligrams of hyaluronic acid which is
- 5:02also found in microvitamin next is
- 5:05vitamin B3 the clinical guidelines
- 5:07suggest that it can improve Skin Barrier
- 5:09function by decreasing water loss
- 5:11through the outer layer of the skin
- 5:13vitamin B3 is also reported to improve
- 5:16complexion by improving pigmentation
- 5:18blotchiness and redness of aging skin
- 5:20there are a few other tools to reverse
- 5:23the signs of skin aging including laser
- 5:25treatment photodynamic therapy and Botox
- 5:28so not filler but Botox you can see that
- 5:31there are plenty of tools available to
- 5:33us today in addition to diet exercise
- 5:35and sleep to help you look significantly
- 5:37younger than your age make sure to check
- 5:39out this next video here on the latest
- 5:41research regarding the best diet and if
- 5:44you want early access to these videos
- 5:45check out the pinned comment where you
- 5:47can find a link to my patreon
About this transcript
This page contains the full transcript of How To Reverse Skin Wrinkles (latest science) by Dr Brad Stanfield, generated from the public captions YouTube serves with the video. The transcript has 998 words across 155 segments, with the original timestamps preserved so you can click any line to jump to that moment in the embedded player.
What you can do with it
Use the transcript to take notes, quote the speaker, build a study guide, generate a summary with ChatGPT or Claude via the YouTube Summary tool, or export it as a timed subtitle file with YouTube to SRT. You can also re-open it in the transcriber to translate the transcript into 100+ languages.
Free YouTube transcript tool
YouTube2Text is a free YouTube transcript generator — no signup, no daily limit. Paste any YouTube link and get the full transcript instantly, with timestamps, click-to-jump, translation to 100+ languages, AI prompts for ChatGPT, Claude, and Gemini, and exports to TXT, SRT, VTT, or Markdown.