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Exam 1 review — Transcript

by Savannah Gilmore · 6,489 words · 1,006 segments · language en · Watch on YouTube

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  1. 0:02All right, guys. Hopefully this one
  2. 0:06works. And we have been having some
  3. 0:08technology issues, but hopefully this
  4. 0:09one works. We're going to do it again.
  5. 0:12Um, but this is just your exam review.
  6. 0:15Um, it is a supplemental help for your
  7. 0:17exam. So, please remember to review
  8. 0:20notes, look at those things that your
  9. 0:23professors have pointed out in class or
  10. 0:25on the slides, the things that are
  11. 0:26highlighted or bolded. um and concepts
  12. 0:30just in general, not just rope
  13. 0:32memorization. But I think you guys are
  14. 0:34going to do great and this is definitely
  15. 0:35going to help you a lot. So let's get
  16. 0:37started. So to begin, we're going to go
  17. 0:40through chapter one starting with macro
  18. 0:42versus micronutrients. So
  19. 0:44macronutrients, we need these in big
  20. 0:46amounts like grams. And these are going
  21. 0:49to be proteins, carbs, lipids, and
  22. 0:52water. Those are the things we need in
  23. 0:55larger amounts and are classified as
  24. 0:57macronutrients. Micronutrients on the
  25. 0:59other hand are smaller amounts. So we
  26. 1:03need them in smaller amounts like
  27. 1:04milligs, micrograms,
  28. 1:06etc. And they include vitamins and
  29. 1:08minerals.
  30. 1:12We have six classes of essential
  31. 1:13nutrients. Um these essential nutrients,
  32. 1:16they do a specific biological function.
  33. 1:18And when we don't have the minimum diet,
  34. 1:20we're going to see a decline in function
  35. 1:21in our body. Um, and typically we can
  36. 1:24add them back into our diet before real
  37. 1:27hardcore damage occurs. Um, as long as
  38. 1:30they haven't been too severely
  39. 1:32deficient. And these are going to
  40. 1:34include our vitamins, minerals, carbs,
  41. 1:36proteins, fats, or lipids, and water.
  42. 1:41So, here's just a big um table. You
  43. 1:45don't need to know it. You just need to
  44. 1:46know the different between energy
  45. 1:48yielding and non-energy yielding
  46. 1:49nutrients. So, our energy yielding
  47. 1:51nutrients, those are going to be our
  48. 1:53carbs, our fats or lipids, and our
  49. 1:56protein. They're actually giving us
  50. 1:57energy that our um bodies can use. Um
  51. 2:01and then our non-energy yielding
  52. 2:03nutrients. These are going to be
  53. 2:04vitamins and minerals. So our body's not
  54. 2:06taking these and converting them into
  55. 2:08ATP or energy for us, but they are being
  56. 2:11used in our body to perform various
  57. 2:13functions.
  58. 2:15All right, we'll keep going. So we have
  59. 2:17different functional categories for
  60. 2:19these nutrients. Um some provide energy,
  61. 2:23promote growth and development, and
  62. 2:25regulate body processes. A lot of these
  63. 2:27are going to do the same thing, but um
  64. 2:30the ones that provide energy, like we
  65. 2:32just talked about, carbs, proteins,
  66. 2:34lipids, um the ones that promote growth
  67. 2:37and development, proteins, lipids,
  68. 2:39vitamins, minerals, water, and the same
  69. 2:43ones regulate our body processes.
  70. 2:47All right, so we'll start with our
  71. 2:48macronutrient carbohydrates. And our
  72. 2:51carbohydrates are going to be made of
  73. 2:52carbon, oxygen, hydrogen. They provide
  74. 2:55four kal per gram. Know that. That's
  75. 2:58important to know. Um it's our major
  76. 3:00source of energy in most cells. Um we
  77. 3:02use carbohydrates the most for energy.
  78. 3:04And there's two types. There's simple
  79. 3:06and there's complex. Simple are readily
  80. 3:08usable forms of carbohydrates like table
  81. 3:11sugar, which is sucrose and blood
  82. 3:13glucose. And our complex carbohydrates
  83. 3:15are going to include starch, glycogen,
  84. 3:17and fiber. Our starch, it's a storage
  85. 3:20form of carb in foods. And our fiber is
  86. 3:22something we cannot digest and it forms
  87. 3:25structures in the plant cell walls.
  88. 3:28Great for our gut, but we can't really
  89. 3:30digest it.
  90. 3:34All righty. The next one we'll talk
  91. 3:35about is protein. Protein has a unique
  92. 3:38um difference between it and carbs and
  93. 3:41that is that it has nitrogen, the only
  94. 3:44macro nutrient um of the three that have
  95. 3:47nitrogen in it. Um, and it also provides
  96. 3:494 ks per gram similarly to carbs, but
  97. 3:53it's made of amino acids. There's 20
  98. 3:55amino acids, but nine are essential,
  99. 3:58which means we have to get them from
  100. 4:00food, from our diet. Our body does not
  101. 4:02make them. And protein is important in
  102. 4:05structural components in our body such
  103. 4:06as bone, muscle, blood, cell membranes,
  104. 4:10especially enzymes, and immune factors.
  105. 4:15All righty. Lipids, fats, our last
  106. 4:17energy yielding macronutrient. It's
  107. 4:20going to be carbon, oxygen, and hydrogen
  108. 4:22just like our carbs were made out of the
  109. 4:25same thing, but it provides 9 kals per
  110. 4:28gram, which is the most out of all our
  111. 4:30macronutrients. So, 9 kals. Keep that in
  112. 4:33mind for your exam. Um, there's two
  113. 4:36types of lipid categories. We have
  114. 4:38saturated fats and unsaturated.
  115. 4:41saturated I think like S for saturated
  116. 4:44means solid room temperature. Um they're
  117. 4:47mainly found in animal sources. They
  118. 4:49raise our blood cholesterol which can
  119. 4:51lead to cardiovascular disease. Um the
  120. 4:53ones that we really want to make a
  121. 4:54staple in our diet are unsaturated fats.
  122. 4:57They're liquid at room temperature and
  123. 4:59they're mainly found in plant sources
  124. 5:01like think olive oil, canola oil,
  125. 5:02vegetable oil and they're a lot better
  126. 5:04for us than saturated fats for our heart
  127. 5:06health.
  128. 5:09Water is another macronutrient that we
  129. 5:11need in the largest quantity. Although
  130. 5:14it doesn't produce um we our body
  131. 5:16doesn't use it to make ATP like the
  132. 5:19other ones, but we do need it for all
  133. 5:22sorts of functions. Um it's used for as
  134. 5:25a solvent, lubricant, a medium for
  135. 5:27nutrient transport to our cells and
  136. 5:29helps regulate our body temperature. And
  137. 5:31we get it from food and drink. And it
  138. 5:33actually is the byproduct of metabolism
  139. 5:36or byproducts of breaking down our
  140. 5:38lipids, proteins, and fat or carbs.
  141. 5:43And then this is just a note. We're made
  142. 5:45of of 60 to 70% water, which is probably
  143. 5:48why we need it in the largest quantity.
  144. 5:52All right, here's just a practice. Um,
  145. 5:54we won't I won't go through it totally,
  146. 5:56but um I'll just show you guys how you
  147. 6:00would go about solving this. Um,
  148. 6:04perfect. So, we know that
  149. 6:08our
  150. 6:11carbs, sorry. Okay, we know that our
  151. 6:13carbs produced four kals per gram. So
  152. 6:17you would just take however many grams
  153. 6:19of carbs we have and we would multiply
  154. 6:21that by the four because it produces or
  155. 6:24it gives us four cakeals per gram and
  156. 6:26then you would multiply that out to get
  157. 6:28the total cake. So again fat it's 9
  158. 6:31kowals per gram. So you multiply that by
  159. 6:349. Protein for
  160. 6:37alcohol is seven although it's not
  161. 6:39really considered an energy yielding
  162. 6:40nutrient just because of how it's
  163. 6:42metabolized in our body but it is seven.
  164. 6:45And then you would just multiply that
  165. 6:46out to get the total. So if that makes
  166. 6:49sense, we will just
  167. 6:52go ahead and get rid of these.
  168. 6:55All righty.
  169. 6:57Perfect. We'll keep going along.
  170. 7:00As long as that makes sense to everyone.
  171. 7:03Okay. So this is just a quick summary
  172. 7:04slide, but carbs produce 4k calories per
  173. 7:06gram. Protein 4k cows per gram. Alcohol
  174. 7:09again not a nutrient because it's not
  175. 7:10really producing um energy in our body
  176. 7:12like carbs, proteins, and fats does. but
  177. 7:14it's still considered one of these. Um,
  178. 7:17and then fats, 9 ks per gram. We use
  179. 7:21these energy producing nutrients um or
  180. 7:23energy yielding nutrients I should say
  181. 7:25to build new compounds in our body to
  182. 7:27perform movements with our muscles and
  183. 7:30to promote nerve transmission within our
  184. 7:32nervous system and also to maintain ion
  185. 7:35balance within cells like our blood
  186. 7:38cells um just different cells in our
  187. 7:40body. So we use energy to do work.
  188. 7:45Okay. So what influences our food
  189. 7:47choices? Well, there's two major
  190. 7:49factors. Um and it's hunger and versus
  191. 7:52appetite. So hunger is a physiological
  192. 7:55internal need for food. Like your body
  193. 7:57is telling you I need food to keep going
  194. 8:00to survive. So it's physiological. We
  195. 8:02really need it for um processes in our
  196. 8:04body to function. While appetite on the
  197. 8:06other hand is just a psychological
  198. 8:08desire to eat food. So, we may not need
  199. 8:12food, but our brain is telling us we
  200. 8:14want food. So, that's the main
  201. 8:16difference between hunger and appetite.
  202. 8:18Um, nutritional status, malnutrition, it
  203. 8:22can refer to over nutrition or under
  204. 8:24nutrition. So, it's just malnutrition is
  205. 8:26just meaning we're not in that just
  206. 8:28right desirable nutrition state.
  207. 8:32Under nutrition, this is when our
  208. 8:33nutrient intake is not meeting our
  209. 8:35needs. So it's less than what we need or
  210. 8:38our nutrient surplus stores are
  211. 8:40depleted. So the the energy um stores we
  212. 8:43have in our body are depleted. We really
  213. 8:45need that food. So we're under um we
  214. 8:48have under nutrition. Um over nutrition
  215. 8:51obviously the opposite. It's a
  216. 8:53consumption of more nutrients than the
  217. 8:55body needs. So more calories than we
  218. 8:56need, more energy than we need. So we're
  219. 8:58probably going to store it as fat which
  220. 9:00could lead and often does lead to
  221. 9:01obesity.
  222. 9:03All righty.
  223. 9:06the scientific method. You guys had some
  224. 9:11brief overview of this. So, we're just
  225. 9:12going to go through it again, but just
  226. 9:14make sure you kind of know what each of
  227. 9:16these do in maybe the step-wise order.
  228. 9:19But our first step, it's a little
  229. 9:20covered, but it's observation where
  230. 9:23we're seeing something, we're
  231. 9:24identifying a problem or a phenomenon.
  232. 9:26Then our second step is we're going to
  233. 9:28see that and then come up with an
  234. 9:30explanation for it. So, we're going to
  235. 9:32form our hypothesis.
  236. 9:34Then from that hypothesis we formed,
  237. 9:35we're going to experiment. We're going
  238. 9:37to design a study to test our
  239. 9:39hypothesis. From that experiment, we're
  240. 9:41going to collect data and analyze the
  241. 9:43results. We're going to use statistic
  242. 9:45methods, various methods to identify
  243. 9:48patterns, correlations, differences, and
  244. 9:50we're going to record those. Then we're
  245. 9:52going to conclude. We're going to either
  246. 9:54say, you know what, my guess, my
  247. 9:56hypothesis was correct, so we're going
  248. 9:57to accept it. Or we're going to say, you
  249. 9:59know what, my hypothesis was so wrong,
  250. 10:01and we're going to reject it. or maybe
  251. 10:03we just need to modify it. And finally,
  252. 10:06we're going to send it for peer review
  253. 10:07and ultimately publication. So many
  254. 10:10people are going to look through it to
  255. 10:11make sure that we did what we're
  256. 10:13supposed to and went through the right
  257. 10:14channels and then we would submit it for
  258. 10:16publication.
  259. 10:19All right. So there's many experimental
  260. 10:21designs in nutrition research. Um
  261. 10:24various ways to experiment. In vitro
  262. 10:27means in glass. So like test tube
  263. 10:29experiments. While in vivo, vivo in life
  264. 10:32means that we're experimenting organisms
  265. 10:35in their natural habitat. So not
  266. 10:37isolated into a test tube or whatever.
  267. 10:40Um the gold standard for experimental
  268. 10:42designs is going to be a randomized
  269. 10:45control trial. And there's various kinds
  270. 10:47of these. We have a double blind where
  271. 10:49the participant nor the researcher knows
  272. 10:51what's going on um or which group is
  273. 10:53getting which um intervention. We have a
  274. 10:56crossover study where participants
  275. 10:59receive both the treatment and the
  276. 11:01placebo. So you're kind of each person
  277. 11:03is being their own tester. Um but it's a
  278. 11:07great way to do it. Or the placebo study
  279. 11:10which is fake treatment such as like a
  280. 11:12sham pill or just um not the real thing.
  281. 11:19All right. So that was chapter one and
  282. 11:21we're going to go into chapter two.
  283. 11:23So these ones can get confusing. the
  284. 11:25dietary reference intake. So, we're
  285. 11:27going to try to keep these straight
  286. 11:28together. And there's five standards of
  287. 11:30DRI. We have our estimated energy
  288. 11:32requirements, our ES. We have our
  289. 11:34recommended dietary allowance, our RDAs,
  290. 11:37adequate intakes, AIS, tolerable upper
  291. 11:40intake levels, ULS, and estimated energy
  292. 11:42requirements, EERS. Um, they differ by
  293. 11:45life stage. So, different life stages it
  294. 11:48may differ. But there's another one
  295. 11:50that's not technically a DRRi, but it's
  296. 11:53still one that we use and it's an
  297. 11:54acceptable macronutrient distribution
  298. 11:56range. So these are set for our
  299. 11:58macronutrients such as carbs, fats, and
  300. 12:00proteins and they're a percentage range
  301. 12:01that we can use for diets.
  302. 12:06All right, so our first one, ES, they
  303. 12:09meet the needs of half of the
  304. 12:11population. So their nutrient amounts
  305. 12:14are estimated to meet the needs for half
  306. 12:16of a population. So that's kind of what
  307. 12:18set this one apart. And Ess cannot be
  308. 12:20set without a functional um biioarker.
  309. 12:24So this means functional markers can
  310. 12:25include like enzymes, cells, organs, um
  311. 12:29just how your body is using these
  312. 12:31things. And this is for groups, not
  313. 12:33individualized. So that's something else
  314. 12:35to note. But know that ES meet needs for
  315. 12:39half of the population. It's not
  316. 12:41everybody.
  317. 12:43RDA's recommended dietary allowances.
  318. 12:45These meet the needs for nearly all
  319. 12:47individuals like in 98% of individuals.
  320. 12:50It's based on ERS, multiple ERS. And
  321. 12:54this nutrient is set to prevent disease,
  322. 12:57not to prevent deficiency, but it's
  323. 13:00going to be higher than what the average
  324. 13:01person needs. So know that this is going
  325. 13:04to meet the needs of nearly everybody
  326. 13:06and is based on ES. So those are just
  327. 13:09some things to note. Um, adequate
  328. 13:11intakes. These are set for nutrients
  329. 13:13where we don't have enough research of
  330. 13:15functional markers to have an E. So, we
  331. 13:19know we don't have enough research about
  332. 13:20this. So, we're just going to set an
  333. 13:21adequate intake. And these can be used
  334. 13:23for individuals. You know, our Esser
  335. 13:26more for groups, not individuals. AIS,
  336. 13:28they can be used for individuals. Um,
  337. 13:30these are based on experimental
  338. 13:31estimates. Um, and
  339. 13:35yeah, to maintain to find nutritional
  340. 13:37status. So, AI's target intake level for
  341. 13:40a nutrient based on people's estimated
  342. 13:42dietary intakes.
  343. 13:45All righty. Tolerable upper intake
  344. 13:47levels. So, these are the max daily
  345. 13:49intake you can um have without it
  346. 13:52causing adverse health effects. It's not
  347. 13:55really a nutrient goal cuz you do not
  348. 13:57want to be intaking the max amount you
  349. 14:00can every day. So, our nutrient intake
  350. 14:02should remain below this upper limit
  351. 14:05ceiling.
  352. 14:09And then we have estimated energy
  353. 14:10requirements, our last RDI. And these
  354. 14:13are our average daily energy needed for
  355. 14:16like for each life stage group. Um it
  356. 14:19depends on various things like how much
  357. 14:21we're exercising, how much energy we're
  358. 14:23expending, height, weight, gender, age,
  359. 14:27um and overall they're used the this um
  360. 14:29estimate is used to promote healthy body
  361. 14:32weight, quality of life, etc.
  362. 14:36Here's a great summary slide if you
  363. 14:37guys, this is in your notes, you can
  364. 14:39find it. Um, it's a great summary slide
  365. 14:41for all of these. But again, ES
  366. 14:44represent half of the population, more
  367. 14:47for groups, not individuals. RDAs used
  368. 14:50to evaluate current intake for specific
  369. 14:53nutrient. It can be more individualized.
  370. 14:56AIS when we don't have that E, we have
  371. 15:00we'll do experimental research to
  372. 15:02establish an AI. um an upper limit or
  373. 15:05upper level intake. This is the max
  374. 15:08amount. So, we usually want to stay
  375. 15:09under this ceiling. It's the max amount
  376. 15:11we can have before bad effects. ERS that
  377. 15:15estimated energy requirement. How many
  378. 15:18calories, how much energy are we needing
  379. 15:20according to various factors like
  380. 15:21exercise, height, weight, gender, etc.
  381. 15:24And then our AMDR nutrient range, that
  382. 15:27percentage of each macronutrient that we
  383. 15:28need.
  384. 15:31All right, guys, stick with me. So,
  385. 15:33nutrient density of food. You guys did
  386. 15:35this in your case study, so you should
  387. 15:36be good to go on this. But again, here's
  388. 15:39a reminder calculation. Um, to calculate
  389. 15:42nutrient density, we're going to divide
  390. 15:44the amount of nutrient in a serving,
  391. 15:45divided by our recommended daily intake,
  392. 15:47and get that value. And then we're going
  393. 15:49to divide our calories in a serving
  394. 15:50divided by our EER, our daily calorie
  395. 15:53need, and we're going to get that value.
  396. 15:55And then we're going to compare the two
  397. 15:57values. So the food is going to be
  398. 15:59nutrient dense if it if it provides a
  399. 16:01greater contribution to your nutrient
  400. 16:03need than your calorie need. So if this
  401. 16:05number is larger than this one, it's a
  402. 16:07nutrient-dense food. So here's an
  403. 16:09example problem you guys can do. Again,
  404. 16:10this is straight from your notes. So I
  405. 16:13you guys did this example in class. Um
  406. 16:16down here we can see that these produce
  407. 16:20similar calories. Actually, soda
  408. 16:22produces a lot more calories, but look
  409. 16:24at all the nutrients we're getting from
  410. 16:26milk.
  411. 16:27So, milk is clearly more nutrient-dense
  412. 16:29than soda.
  413. 16:32Okay, nutrition facts panels. There's so
  414. 16:34much on here, but we're going to try to
  415. 16:36simplify it. So, what I've highlighted
  416. 16:38here are all the things that are
  417. 16:39required on a nutrient fact label. Our
  418. 16:42serving size is required. Calories,
  419. 16:45fats, saturated fat, trans fats,
  420. 16:47cholesterol, sodium, potassium, carbs,
  421. 16:49dietary fiber, added sugars, and
  422. 16:52protein. Not to mention a few
  423. 16:55micronutrients like calcium, iron,
  424. 16:57vitamin D, which isn't on here. Those
  425. 17:00things are required. So, our DRRI,
  426. 17:03they're recommendations from the food
  427. 17:05and nutrition board. Um, again, we
  428. 17:09talked about all of those earlier, our
  429. 17:11ERS, AIS, all that. Um, our DRVs or
  430. 17:14daily recommended values are set for
  431. 17:17energy producing nutrients and
  432. 17:19cholesterol and sodium. And they're
  433. 17:21found over here. They're percent daily
  434. 17:22values. They're based on a 2,000 calorie
  435. 17:25per day diet. Um, so keep that in mind
  436. 17:28and you can see them over here. Um, and
  437. 17:31then RDI are set for vitamins and most
  438. 17:34minerals on a food label.
  439. 17:36So again, you can find that over there.
  440. 17:38Percentage value as well.
  441. 17:41All right. So just some brief overview
  442. 17:44of the dietary guidelines that we try to
  443. 17:46follow. Um, follow a healthy eating
  444. 17:48pattern across lifespan. Focus on
  445. 17:50variety and nutrient density and how
  446. 17:53much. Moderation is key on some things
  447. 17:56because every food has a place in our
  448. 17:58diet. No food is bad. Um, limit calories
  449. 18:02from added sugars and saturated fats and
  450. 18:04reduce sodium. Remember those three
  451. 18:05things that Mr. Hand is always talking
  452. 18:07about, but that we want to watch out for
  453. 18:09are added sugars, saturated fats, and
  454. 18:11and sodium. Those are the ones we want
  455. 18:13to limit and have in moderation. Um, and
  456. 18:17we should try to shift to healthier food
  457. 18:19and beverage choices, um, and support
  458. 18:21healthy eating patterns for all. And
  459. 18:23then these are just ways that we can put
  460. 18:24them into action, these dietary
  461. 18:26recommendations. Um, take into account
  462. 18:28your current health status, your family
  463. 18:30history. Maybe your family history has
  464. 18:32or maybe your family has history of
  465. 18:34heart disease. So maybe you need to be
  466. 18:35more cautious about certain foods. Um,
  467. 18:38identify specific changes you need to
  468. 18:39make. Develop a plan to achieve these
  469. 18:42changes and then see whether the changes
  470. 18:45are really effective. Are they helping
  471. 18:47you follow those dietary guidelines?
  472. 18:51Okay, my plate. This is a fun one and a
  473. 18:55really great tool for using in our daily
  474. 18:57life. Um, it helps us balance our
  475. 18:59calories. Um, basically
  476. 19:03avoid oversized portions when it comes
  477. 19:05to making your My Plate. Um, foods that
  478. 19:08you really don't have to worry about and
  479. 19:10you can increase a lot are your fruits
  480. 19:12and vegetables. You want to make half of
  481. 19:13your plate fruits and vegetables. make
  482. 19:15at least half of your grains whole
  483. 19:17grains and switch our milk from whole
  484. 19:21fat to low fat or fat-free option. Um,
  485. 19:24foods to reduce again those added
  486. 19:26sugars, sodiums, saturated fats. And
  487. 19:29then swap out water instead of high
  488. 19:32sugar drinks. Those are the main
  489. 19:34recommendations for my plate.
  490. 19:37All right, guys. We just made it through
  491. 19:38chapter 2. Last chapter to go. We get
  492. 19:41into digestion in this chapter. So our
  493. 19:44first we'll start with the organization
  494. 19:45of the human body. So how is the human
  495. 19:47body organized? Well, we start at a
  496. 19:48chemical level. Our atoms combine to
  497. 19:50form our cells. Cells combine to form
  498. 19:52tissue. Tissues combine to form organs.
  499. 19:55Organs work together to form an organ
  500. 19:58system. And then organ systems work
  501. 19:59together to make you and me organisms.
  502. 20:02So I think it makes pretty pretty good
  503. 20:03sense. But just keep those stepwise
  504. 20:06order in mind.
  505. 20:10major digestive organ system. The major
  506. 20:13organs, mouth, esophagus, stomach, small
  507. 20:16intestine, large intestines, and anus.
  508. 20:18And these are in the order of which
  509. 20:20digestion occurs. Um, and then we have
  510. 20:22accessory organs that help out, but
  511. 20:24they're not main organs um that are a
  512. 20:27part of the digestive system, but still
  513. 20:28really important, and that's the liver,
  514. 20:30pancreas, and gallbladder, or in other
  515. 20:32words, llamas get pizza. A helpful way
  516. 20:34to remember if you need.
  517. 20:38All righty. So the functions of the
  518. 20:40digestive system
  519. 20:42main function is to absorb the nutrients
  520. 20:44that we're that we're intaking excreting
  521. 20:47waste making nutrients for cells out of
  522. 20:49the energy that we intake. Um it plays a
  523. 20:52role it plays a role in immune system
  524. 20:55and it houses the microbiota in our body
  525. 20:58and our gut which is really vital for so
  526. 21:01many things but especially digestion and
  527. 21:04a healthy gut. Um, our digestive system
  528. 21:07is controlled by hormones and the
  529. 21:09nervous system.
  530. 21:11All right. So, the GI tract, it's made
  531. 21:13of four layers and I have it organized
  532. 21:15as the very innermost layer to the
  533. 21:17outermost layer. So, we have the mucosa
  534. 21:20in the very innermost layer which is the
  535. 21:22epithelial cells and glands. Then we
  536. 21:24have one layer out is the sub mucosa
  537. 21:27that has the blood vessels and they and
  538. 21:29it carries nutrients in those. Um and
  539. 21:31then one more layer out we have muscle
  540. 21:34that is actually moving the food forward
  541. 21:36which we'll talk about later the
  542. 21:37difference between paristalsis and
  543. 21:39segmentation. Um and then we have the
  544. 21:41sarosa which is actually protecting the
  545. 21:43tract overall. And then just a little
  546. 21:45fun fact that you guys mentioned or that
  547. 21:47Mr. Hen mentioned in class but our GI
  548. 21:49tract is 15 ft long which is pretty wild
  549. 21:52that it fits inside of our body's
  550. 21:55sphincters. These are really important
  551. 21:57part of the digestive system. They're
  552. 21:59ringing like muscles and they open and
  553. 22:01they close to control the flow of the
  554. 22:03food that you're eating and the flow of
  555. 22:05the contents in the GI tract. Um the
  556. 22:08lower esophageal sphincter, again the
  557. 22:10numbers correlate to where they're
  558. 22:11located. Um and they do kind of what you
  559. 22:15think they do depending on where they're
  560. 22:17located, but the lower esophageal
  561. 22:19sphincter, it prevents backflow of the
  562. 22:22stomach back into the esophagus. Um,
  563. 22:24pyloric sphincter controls the flow of
  564. 22:26stomach contents into the small
  565. 22:27intestine so that it does not flow back
  566. 22:29into the stomach. The sphincter of odi
  567. 22:32it controls the flow of bile from the
  568. 22:33common bile duct into the small
  569. 22:35intestine. Ilioal valve prevents the
  570. 22:37contents of the large intestine from
  571. 22:39re-entering the small intestine and the
  572. 22:41anal sphincter prevents defecation until
  573. 22:43the person wants to do so. So all of
  574. 22:46these basically are preventing backflow
  575. 22:49and keeping the food moving forward
  576. 22:52which is essential for digestion.
  577. 22:54Okay. So speaking of food moving
  578. 22:56forward, how food is actually moving
  579. 22:58because without um segmentation
  580. 23:01paristalsis, our food is just going to
  581. 23:03be sitting in one spot which is not
  582. 23:06good. It might move a little because of
  583. 23:08gravity but overall it's not going to
  584. 23:09move very well. So parasolsis and
  585. 23:12segmentation great way to know the
  586. 23:14difference between these is paristelsis
  587. 23:16we're actually pushing forward. So
  588. 23:19parasolsis starts with a P. Pushing
  589. 23:21forward starts with a P. That's how I
  590. 23:22remember. So paristelsis we're actually
  591. 23:25moving forward. Segmentation on the
  592. 23:26other hand is just mixing back and
  593. 23:28forth. So it's mixing the food in with
  594. 23:30enzymes which is also great for our
  595. 23:32digestion. But so each are important but
  596. 23:35they're doing different things. So
  597. 23:36again, paristelsis food is mixing with
  598. 23:38digestive secretions, but it's actually
  599. 23:41getting propelled or pushed down the GI
  600. 23:43tract and it's waves of contractions
  601. 23:45because we do have that muscle layer on
  602. 23:48um in our GI tract that is actually
  603. 23:50doing the squeezing and shortening to
  604. 23:51push it. Segmentation, it's the back and
  605. 23:54forth movement, breaking apart context,
  606. 23:56make content, mixing with enzymes, and
  607. 23:58it's occurring in small intestine
  608. 24:00alongside of paristelsis.
  609. 24:03um mass movements, paraselsis over wides
  610. 24:06widespread area happening in the large
  611. 24:08intestines and then finally elimination,
  612. 24:11urine, feces, vomiting, all ways that we
  613. 24:13eliminate food or um excretions. Um a
  614. 24:17normal time for a meal to make it
  615. 24:21through your digestive system is 24 to
  616. 24:2260 hours, which is a really long time.
  617. 24:25Um so when you're eating something, it's
  618. 24:27going to be um working its way for a
  619. 24:30while.
  620. 24:32Wonderful. the wonderful world of
  621. 24:34enzymes or in other words aces. Most
  622. 24:36enzymes you see are going to end in aces
  623. 24:39or ACE which is super helpful. Not all
  624. 24:41of them but a lot of them. Um what are
  625. 24:43enzymes? They are proteins and they
  626. 24:45speed up reactions. That's their main
  627. 24:48function. That's what they're there for.
  628. 24:50They act on a specific substance. Um
  629. 24:52carbs, proteins, fats, whatever it may
  630. 24:54be. Most enzymes are going to be made in
  631. 24:57our pancreas and small intestine which
  632. 25:00our small intestine is essential for
  633. 25:02absorption. So it makes sense that the
  634. 25:03pancreas and small intestines are making
  635. 25:05our enzymes. But a small amount are made
  636. 25:07in our stomach and our salivary glands
  637. 25:09in our mouth. Um they the enzymes
  638. 25:12catalyze hydrarolysis reactions or we
  639. 25:14removing water to break um bonds or
  640. 25:17whatever it may be. And then inadequate
  641. 25:20enzyme production can lead to some
  642. 25:22issues like incompleted digestion or
  643. 25:25limited absorption. We're not getting
  644. 25:26all the nutrients we could. So it's
  645. 25:28important to have enzymes for digestion.
  646. 25:31Some other secretions to know in our
  647. 25:33mouth we have saliva and there's enzymes
  648. 25:35in saliva that break down starch. In our
  649. 25:37stomach we have acid which activates um
  650. 25:41enzymes that break down protein. We have
  651. 25:43bile in our small intestines which help
  652. 25:45break down fat um through
  653. 25:47emulsification,
  654. 25:49but we'll talk more about that later.
  655. 25:51Okay, so moving through the GI tracts,
  656. 25:52we're going to start where digestion
  657. 25:54begins, the mouth and the esophagus. So
  658. 25:56digestion begins in the mouth, and we're
  659. 25:59going to chew food, mix it with enzymes,
  660. 26:01break it down mechanically by chewing,
  661. 26:04and our saliva is going to mix with the
  662. 26:06food, forming a bolus, which is like a
  663. 26:08big lump of food. And we're going to
  664. 26:11swallow that bolus and it's going to go
  665. 26:12through our esophagus and our epiglatus
  666. 26:14is going to cover the larynx so that
  667. 26:16that food is not going where it's not
  668. 26:18supposed to be. Um, and then what's in
  669. 26:20our saliva? Many things to help break
  670. 26:23down what we're eating, although we're
  671. 26:25not breaking down a lot in our mouth.
  672. 26:27Um, lizoomes to destroy bacteria, mucus
  673. 26:30to kind of lubricate and then like kind
  674. 26:32of like hold the bolus together because
  675. 26:34it's like slimy and gross. Um, it's like
  676. 26:37the slimy gross glue. And then
  677. 26:40amalayise, which breaks down a small
  678. 26:42portion of starch into simple sugars,
  679. 26:43not a lot, but a little bit. And then
  680. 26:45lipase, which begins fat digestion.
  681. 26:49All right, guys. We're doing great.
  682. 26:50Ramas there. Um, this is just a small
  683. 26:52caveat, but smell and taste. A lot of
  684. 26:55you are going to know this, but we have
  685. 26:56five um tastes. Salty, sour, sweet,
  686. 26:59bitter, unami, umami, excuse me. Um, and
  687. 27:02taste is enhanced by our oldactory cells
  688. 27:04in the nose. So a lot of times if you
  689. 27:06can't smell, you can't taste food very
  690. 27:08well because olfactory cells in our nose
  691. 27:10help us to taste better.
  692. 27:13Okay. Now that our food has moved
  693. 27:15through the mouth and esophagus, we get
  694. 27:17to the stomach. Food enters the stomach
  695. 27:20via that sphincter we talked about that
  696. 27:21lower esophageal sphincter and digestion
  697. 27:24continues to the stomach. But a small
  698. 27:26amount of digestion occurs here. really
  699. 27:28only protein gets digested here or
  700. 27:30broken down by enzymes because it's so
  701. 27:32acidic because gastric juices in our
  702. 27:34stomach contain HCL which is
  703. 27:37hydrochloric acid and intrinsic factor
  704. 27:40from parietal cells but we have a nice
  705. 27:43enzyme here that breaks down protein and
  706. 27:47pepsinogen this is the non-active form
  707. 27:50but it becomes activated by HCL
  708. 27:54into something that can digest the
  709. 27:56protein so pepsinogens is important for
  710. 27:58protein digestion and gastroglyphase
  711. 28:01from chief cells. So, a little bit of of
  712. 28:02fat breakdown occurs here. Gastrin, it's
  713. 28:05a hormone made in the stomach and it
  714. 28:07controls the release of HCL and
  715. 28:09pepsinogen.
  716. 28:11So, that's something to know. It's a
  717. 28:13hormone. Like we talked about, hormones
  718. 28:15do control our um or part of our reg
  719. 28:19regulation of our digestive system.
  720. 28:22All right, guys. We'll keep moving. So
  721. 28:23in our stomach, gastrin leads to the
  722. 28:26release of HCL and pepsinogen. And like
  723. 28:28I said, HCL, hydrochloric acid,
  724. 28:30activates our pepsinogen
  725. 28:33into pepsin. And our pepin breaks down
  726. 28:37proteins to small peptides, which are
  727. 28:39like smaller chains of amino acids.
  728. 28:44All righty.
  729. 28:47In the stomach, the bolus goes through
  730. 28:50the lower esophageal sphincter into the
  731. 28:52stomach. And in the stomach, secretions
  732. 28:56make the bolus become like a kim, which
  733. 28:59is like a more like liquid version of
  734. 29:01the food. It's just like a slushy slush.
  735. 29:03It's really nice picture. Um, and then
  736. 29:06once it's a kim in the stomach, it keeps
  737. 29:09going to the small intestine and the
  738. 29:11pyloric sphincter allows the kim to flow
  739. 29:13into the small intestine. um and it
  740. 29:15closes so that it doesn't go back up
  741. 29:17into the stomach. And then glucose
  742. 29:19depend dependent insulin tropic peptide
  743. 29:22slows the release into the small
  744. 29:24intestine. I don't this isn't really
  745. 29:26something you need to spend a lot of
  746. 29:28time memorizing at all, but it's just
  747. 29:30something to note. Um in our stomach
  748. 29:32expands a lot. It can expand from 2 oz
  749. 29:35to 16 cups when it's full. Um, and food
  750. 29:39typically stays in our stomach from like
  751. 29:401 to four hours
  752. 29:43or sorry, it's like takes about 1 to
  753. 29:45four hours from the stomach for the food
  754. 29:46to get from the stomach to our small
  755. 29:48intestine.
  756. 29:50All righty. So, we've moved from the
  757. 29:52mouth, esophagus now to and the stomach
  758. 29:55to the small intestine. This is our
  759. 29:58major side of absorption um or digestion
  760. 30:00and absorption. Most of absorption
  761. 30:03occurs here. So on the exam if you'd
  762. 30:05asked like which organ does the most
  763. 30:08absorption in the digestive system you
  764. 30:10would say the small intestine. Um and
  765. 30:13it's divided into three sections. The
  766. 30:14dueum, the jugenum and the ilium.
  767. 30:19So here's all the things that kind of
  768. 30:21get absorbed and digested in the small
  769. 30:24intestine. We have glucose, minerals,
  770. 30:26amino acids, vitamins, alcohol, water,
  771. 30:28fat. So literally almost b everything
  772. 30:32does get absorbed here minus a few
  773. 30:36things.
  774. 30:38All right. In the small intestines we
  775. 30:39have small intestine villi which um
  776. 30:44circular folds and finger-like
  777. 30:45projections on the surface of our small
  778. 30:48intestine brush border. They their main
  779. 30:51goal is to increase the surface area and
  780. 30:54cause kime to like move slowly through a
  781. 30:57spiral path to allow for more absorption
  782. 31:00and it also helps mix the kim with more
  783. 31:03digestive juices and um again that
  784. 31:06surface area allows it to come into
  785. 31:07contact with even more villi.
  786. 31:10Um this process all is aided by
  787. 31:12segmentation too which again remember
  788. 31:14segmentation is not moving forward it's
  789. 31:16just like mixing.
  790. 31:19Villi are lined with interasittes and um
  791. 31:22they secrete enzymes which help absorb
  792. 31:25nutrients and other cells also secrete
  793. 31:28mucus and hormones. Um interosytes have
  794. 31:31a brush border. They're that are lined
  795. 31:33with microbilli and microbilli are
  796. 31:36another thing that are covered with
  797. 31:37digestive enzymes that help us to digest
  798. 31:40and absorb even more food. Okay, again
  799. 31:44our accessory organs, llamas get pizza,
  800. 31:46liver, gallbladder, pancreas. They work
  801. 31:49alongside of our small intestine to aid
  802. 31:51in digestion and absorption because
  803. 31:53again most of our enzymes are produced
  804. 31:56by our pancreas and our small
  805. 31:57intestines. Um but bile is produced by
  806. 32:00the liver, stored in the gallbladder and
  807. 32:02it helps us in fat digestion and
  808. 32:04absorption. Um by emulsifying fat which
  809. 32:07is basically just means breaking large
  810. 32:09fat into smaller tiny droplets. Um and
  811. 32:12then um bile is reabsorbed in the illium
  812. 32:16which is a portion of the small
  813. 32:17intestine and it can be returned to the
  814. 32:20liver. So we actually recycle the bile
  815. 32:22or interohypatic circulation. Fancy way
  816. 32:26of saying we recycle bile. a small
  817. 32:28amount of bile not reabsorbed and it's
  818. 32:30excreted in feces.
  819. 32:34Um our pancreas again pancreas produce a
  820. 32:37lot of those enzymes and juices that we
  821. 32:38need to digest food. Our sodium
  822. 32:41bicarbonate it helps neutralize acidic
  823. 32:43kime cuz remember kim is coming from the
  824. 32:45stomach where we had HCl and just a lot
  825. 32:47of acid gastrin like all that stuff
  826. 32:50that's just causes it to be a very
  827. 32:52acidic environment. So sodium
  828. 32:54bicarbonate helps neutralize the acidic
  829. 32:56kim when it gets to the small intestine.
  830. 32:58Pancreatic amalase helps digest starch
  831. 33:01in the small intestine. Pancreatic
  832. 33:03lipase digest fats and then proteases
  833. 33:06digest proteins. So these kind of um
  834. 33:08these words the names of the enzymes go
  835. 33:10with kind of what they digest
  836. 33:13which is helpful some of them.
  837. 33:16Okay. So we've moved from mouth,
  838. 33:17esophagus, stomach, small intestine, and
  839. 33:19now we're at the large intestine.
  840. 33:21There's three main parts of our large
  841. 33:23intestine. We have the colon, the anus,
  842. 33:24and the rectum. There's three main
  843. 33:26functions, but our large intestine
  844. 33:28houses our microbiota where live
  845. 33:30bacteria is living in our gut that helps
  846. 33:32us um to keep our GI tract healthy and
  847. 33:36helps us um just so there's so many
  848. 33:40benefits. Some it's even linked to
  849. 33:41mental health in some cases. Um some
  850. 33:43research suggests. So, it's really good
  851. 33:45to have healthy bacteria in our guts. Um
  852. 33:50it forms and expels feces our large
  853. 33:51intestines and then it also absorbs
  854. 33:53water and electrolytes.
  855. 33:55Um the large intestine is the main site
  856. 33:57where electrolytes are absorbed like
  857. 33:59sodium and potassium but essentially
  858. 34:01everything else is absorbed in our small
  859. 34:03intestine.
  860. 34:06our gut microbiota. Again, this live
  861. 34:08bacteria helps us control pathogenic
  862. 34:10bacteria, synthesize vitamin K, help
  863. 34:13with lactose digestion, and digesting
  864. 34:16and metabolizing complex carbs, fibers,
  865. 34:18and starches, and synthesized biotin.
  866. 34:21So, there's so many benefits to um our
  867. 34:24gut microbiota.
  868. 34:28Okay, so what the actual bacteria in our
  869. 34:32gut microbiota are called probiotics.
  870. 34:35They're the live bacteria. We can find
  871. 34:37these in food and supplements, but they
  872. 34:39colonize our large intestine and they
  873. 34:41provide health benefits. Like we just
  874. 34:42talked about all those health benefits.
  875. 34:44So, here's some foods they can be found
  876. 34:46in yogurt, kefir, miso, a lot of
  877. 34:48supplements you can get from the store.
  878. 34:50Um the prebiotics on the other hand,
  879. 34:53they're not the live bacteria. They're
  880. 34:55the food for the live bacteria to um use
  881. 34:59to grow. in um their various food
  882. 35:03ingredients, but they're non-digestible
  883. 35:05carbohydrates. Um they promote the
  884. 35:07growth of healthy bacteria. Again,
  885. 35:09prebiotics are the food for probiotics.
  886. 35:12Um some examples are inulin and
  887. 35:15resistant starches.
  888. 35:18So here again, probiotics are alive.
  889. 35:20Remember that they're the living ones.
  890. 35:22Prebiotics, they're just a form of fiber
  891. 35:24that serve as a food for probiotics. And
  892. 35:26here's some sources. Um, maybe just keep
  893. 35:29in mind a few of those in case you get a
  894. 35:32question.
  895. 35:35All right, foods that increase acid
  896. 35:36reflux. Not a fun condition to have. Um,
  897. 35:39but foods that increase it are typically
  898. 35:41more acidic. Um, obviously like citrus
  899. 35:44fruits, caffeine, chocolate even. You
  900. 35:47probably don't think that's acidic, but
  901. 35:48it actually is more acidic than others.
  902. 35:51um fatty foods, especially spicy foods,
  903. 35:54onions, tomatoes, all these things kind
  904. 35:56of have to watch out for if you have
  905. 35:58acid reflux.
  906. 36:01Intestinal gas. Intestinal gas, it's
  907. 36:03when um we have fermentation of those
  908. 36:05undigested carbohydrates or prebiotics
  909. 36:08that we intake by bacteria in large
  910. 36:11intestine. So if we don't digest the
  911. 36:14carbs and they make it to our large
  912. 36:15intestine, um fermentation happens and
  913. 36:18it builds up gas.
  914. 36:22We call it intestinal gas. Okay. The
  915. 36:24main difference between constipation and
  916. 36:25diarrhea. Some of this you'll probably
  917. 36:28just know from just common sense. Um but
  918. 36:31constipation is when we have difficult
  919. 36:33or infrequent bowel movements, um slow
  920. 36:35movement, fluid is absorbed in many
  921. 36:38cases or many causes, excuse me. um
  922. 36:41diabetes, IBS depression can cause this,
  923. 36:43pregnancy, anti-depressants can cause
  924. 36:45this, medication supplements and a low
  925. 36:48fiber diet. So, we can really help this
  926. 36:51um with a higher fiber diet. So, fiber
  927. 36:53is important. Um diarrhea on the other
  928. 36:56hand, it's very loose, watery stools
  929. 36:58like more than three times a day. Not a
  930. 37:00comfy situation to be in. Um, there's
  931. 37:03multiple causes for having diarrhea, but
  932. 37:05we could have bacterial or viral
  933. 37:07infections from maybe we had
  934. 37:09contaminated food or water, parasites,
  935. 37:11food intolerances, IBS, intestinal
  936. 37:14diseases, large amounts of unabsorbed
  937. 37:17substances. So, if we get too much of
  938. 37:18those unabsorbed carbs, complex carbs,
  939. 37:21that could be really not a good deal.
  940. 37:24Um, or other unabsorbed substances for
  941. 37:27that matter. Um, fluid secreted instead
  942. 37:30of absorbed. So yeah, we don't absorb
  943. 37:32the fluid that we should be. Um and it's
  944. 37:34secreted in diarrhea.
  945. 37:36Not fun. Um treatment for constipation.
  946. 37:40Again, high-fiber diets. So adding fiber
  947. 37:42to our diets is really important for um
  948. 37:46for constipation treatment and regular
  949. 37:48bowel movements in general. Um drinking
  950. 37:50more fluids, developing um more regular
  951. 37:54bowel habits, relaxing some also
  952. 37:57exercise. Exercise is really important.
  953. 37:59So, these are great ways um that we can
  954. 38:01actually um help with this versus we you
  955. 38:06can take some medications if it's
  956. 38:07serious like laxative stool softeners.
  957. 38:10Um but you might want to avoid lubricant
  958. 38:12laxatives like mineral oil cause some
  959. 38:15unforeseen side effects. Um so IBS
  960. 38:19versus IBD irrital bowel syndrome it's
  961. 38:22in 10 to 15% of the population
  962. 38:24unfortunately. Um, it's going to be
  963. 38:26characterized by irregular bowel
  964. 38:28function, abdominal pain, and
  965. 38:30distension.
  966. 38:32Treatment could be to watch trigger
  967. 38:34foods. You just have to keep an eye out
  968. 38:35for the foods that trigger you. A FODMAP
  969. 38:38diet, which we briefly talked about in
  970. 38:40class. Um, not a fun thing to have to
  971. 38:42follow. Smaller meals, peppermint oil,
  972. 38:45maybe have to go gluten-free. Just have
  973. 38:47to see what works for you. Um some
  974. 38:50causes abnormal abnormal intestinal
  975. 38:53motility, stress,
  976. 38:56altered gut immunity, intestinal
  977. 38:58dispiosis, many causes, not a fun thing.
  978. 39:01On the other side of it, we have
  979. 39:03inflammatory bowel disease. And this
  980. 39:05happens in one in every 225 people. So
  981. 39:08that's quite a few people um across the
  982. 39:11world. But it's it can be it's basically
  983. 39:15chronic intestinal disease um such as
  984. 39:17like ulcerative colitis, Crohn's
  985. 39:20disease. Um it's when reoccurring
  986. 39:23inflammation and ulceration of the large
  987. 39:25intestines. So this is not a fun um
  988. 39:27situation and could be really painful
  989. 39:29and uncomfortable. Um treatments
  990. 39:31typically it's medication, antibiot
  991. 39:34antibiotics and surgery. And we really
  992. 39:37don't know the cause, but it's an
  993. 39:39inflammatory response. Could be um or
  994. 39:42could be genetic. We don't really know.
  995. 39:46Okay guys, that is all I have for you
  996. 39:48tonight. Um but go crush your first
  997. 39:50exam. You guys are going to do great.
  998. 39:52And remember to
  999. 39:54review your notes. Um use this as a
  1000. 39:57supplemental review guide, but review
  1001. 40:00those notes. Look at those main bolded
  1002. 40:02underlined highlighted things. things
  1003. 40:04that maybe Professor Hand or Professor
  1004. 40:06Mingi have pointed out to you. Um, yeah.
  1005. 40:09And you're going to do great.
  1006. 40:12All right, guys.

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