Endodontics lecture- Irrigants and intracanal medicaments. — Transcript
Full transcript
- 0:03irance and
- 0:07inal endodontic
- 0:10treat cleaning shaping are the initial
- 0:13steps which we are we have to take to
- 0:17shaping
- 0:19instruments CLE instruments cannot be
- 0:22helpful okay basically people s shaping
- 0:25and cleaning all those can be done by
- 0:27instrument but actually cleaning needs
- 0:28irance okay
- 0:35microbial
- 0:41infection seven requirements
- 0:45an mechanical flushing non-toxic
- 0:49biocompatible dissolves the necrotic and
- 0:51vital PP tissue lubricant removes the SP
- 0:54layer and low surface tension irant
- 1:00the most important one sodium
- 1:01hypochloride the Eda the chlorexidine D
- 1:04gluconate and the Mt
- 1:07a sodium hypochloride that is NCL it is
- 1:12a reducing agent clear straw color
- 1:15solution containing 5% available
- 1:18chlorine okay so
- 1:20na it ionizes and produces hypochlorous
- 1:24acid and hypochloride ion and these two
- 1:27what they do they provide antimicrobial
- 1:30activity sodium hypochloride
- 1:33concentration basically generally
- 1:36concentration
- 1:38range5 to 5.2% solution however
- 1:432.5%
- 1:46because
- 1:49toxity
- 1:532. but what happens is when you reduce
- 1:56the concentration the effectiveness also
- 1:58lessens so how how will you compensate
- 2:00for
- 2:07it and passive
- 2:18ulty 2
- 2:25minutes next most
- 2:28effective so this is the most effective
- 2:31irrigant in dissolving the
- 2:35pulp okay to uh
- 2:38Na work it works in two phases so it
- 2:42causes the destruction of bacteria by
- 2:44two phases first is the penetration in
- 2:46through the bacterial wall bacterial
- 2:48cell wall and second is the chemical
- 2:51combination with the protoplasm Okay so
- 3:02it will cause disruption of the DNA
- 3:04synthesis okay so this uh sodium hypoc
- 3:08chloride had certain drawbacks first of
- 3:11all it has cyto toxicity problem and
- 3:13that is the reason we are using 2.5%
- 3:16concentration or lesser concentration
- 3:18okay even though 5.2 was more effective
- 3:21and it does not remove the inorganic
- 3:23components of failure it is unpleasant
- 3:25taste and it requires cool place okay so
- 3:28you have to keep it in cool place so it
- 3:30is also kind of drawback for
- 3:34it
- 3:37Ed it is ethylene diamine Tetra acetic
- 3:41acid and uh it is a chating agent and
- 3:44was given by nigar it is nontoxic
- 3:47irritating in Weak solution okay so it
- 3:49is a chating agent sodium hypoc chloride
- 3:51reducing agent Ed chating agent or
- 3:54non-toxic irritating weak solution so it
- 3:57is non-toxic sodium hypochloride toxic
- 4:00okay High concentration so what it does
- 4:02it is highly stable chilate okay so it
- 4:06forms highly stable chilate in
- 4:08combination with heavy metals okay so
- 4:10the function is function it forms
- 4:12calcium
- 4:20solution will become
- 4:22more it will be easier to instrument
- 4:26therefore this Eda it is helpful in
- 4:29cleaning and shaping to okay so more
- 4:32exposure more demoralization okay and
- 4:35the second thing is that it removes the
- 4:43SM first of all
- 4:52[Music]
- 5:01how do you use it in the clinics it is
- 5:03177% Ed for 1 minute followed by final
- 5:07rinse with na
- 5:10okay chlorohexidine
- 5:13dluc 2% and it is a broad spectrum
- 5:18antimicrobial and mainly it works on
- 5:22analis uh it is the most common pathogen
- 5:25in the root canals okay and it also it
- 5:28has the property of subst anity Chlor
- 5:31digluconate has a property of
- 5:32substantivity means sustained
- 5:34availability it gets absorbed and it
- 5:37will be released in between durations
- 5:40and it is less toxic but the main thing
- 5:42is that it does not do removal of this m
- 5:45therefore you have to use it with
- 5:47conjugation with irant you cannot use it
- 5:49alone you have to use it with
- 5:53Igan and how does it work it also
- 5:56penetrates the cell membrane and it
- 5:57causes coagulation of the Cy plas
- 6:00content we had studied uh before in Eda
- 6:04that it
- 6:06[Music]
- 6:07causes sorry in uh sodium hypochloride
- 6:11uh that it disrupts the DNA synthesis
- 6:14and here we have studied that it just
- 6:17coagulates the coplas so um the first
- 6:22one was sodium hypochloride it was a
- 6:24reducing agent then we studied that uh
- 6:27um second one which is the DTA it was a
- 6:30chating agent and then we studied that
- 6:33the chlorexidine digluconate it is a
- 6:36antimicrobial agent
- 6:39okay the next one is Mt a it is a
- 6:42mixture of tetracycline isomer uh citric
- 6:46acid and a detergent so it is a mixture
- 6:48of tetracyclin isomo citric acid and a
- 6:51detergent which is 280 so this tety
- 6:54isomer provides antibacterial effect so
- 6:57Mt ad it is used to final rinse this Mo
- 7:02to remove this smer it is used as a
- 7:04final rinse to remove the smer and the
- 7:07regime is 1.3 na CL irrigation is done
- 7:12and then you use the mt8
- 7:14okay now the
- 7:18factors affecting the efficacy of
- 7:20irrigant first is the adequate
- 7:23irrigation is next three then frequent
- 7:25irrigation is done the diameter of canal
- 7:27and exchange of pollution temperature of
- 7:29a
- 7:31seal and then the passive ultrasonic
- 7:35irrigation so more the diameter less uh
- 7:39better will be the irrigation and
- 7:42temperature the no na temperature
- 7:44increase okay now certain irrigation
- 7:48guidelines are
- 7:50there irrigation guidelines uh in that
- 7:54uh the one thing and the only one thing
- 7:56you need for irrigation is a lure lock
- 7:59syring
- 8:00and that has to be disposable obviously
- 8:03and what uh what is the you know cor
- 8:07what is special about the syringe is
- 8:09that it has side winds so there is no
- 8:12ayal Force so it will produce force in
- 8:15this direction no pical force will be
- 8:17there so there will be no cage in the
- 8:20per radicular area okay so um there
- 8:24should be room between the needle and
- 8:25the root canal so when you insert the
- 8:27needle there should be some room some
- 8:29space between the needle and the root
- 8:31canal so that the irrig irrigating
- 8:34solution you it can you know uh get back
- 8:37towards the coronal aspect it should not
- 8:40come here downwards okay and you have to
- 8:42insert the needle passively to not apply
- 8:44much force and the needle should not
- 8:47bind if it is binding that means the
- 8:49space in between is not present so when
- 8:51you inject in such situation it will
- 8:54definitely go in this direction and it
- 8:56will cause infection and further
- 8:58damage so you have to inject with little
- 9:01or no pressure and there should be
- 9:03return of return flow of solution okay
- 9:06so the solution will return towards the
- 9:09coronal aspect and you have to use a gge
- 9:11to soak the solution and after
- 9:14irrigation dry it and you you can suck
- 9:18the remaining irrigation solution back
- 9:19with the plunger okay you have to dry it
- 9:21and you have to suck the remaining
- 9:22solution and then the final drying it is
- 9:25done with absorbent paper the final
- 9:27drawing is done with absorbent paper and
- 9:29the clinical significance is sodium hyp
- 9:31chloride accident uh which occurs when
- 9:33you accidentally give a lot of pressure
- 9:36in the pical area and uh you inject the
- 9:39solution downwards so the hypop oride is
- 9:41toxic so it causes toxicity and necross
- 9:44the area okay next we'll study about the
- 9:47inra canal
- 9:50medicaments so why do we need intra
- 9:53Canal medicaments we have done cleaning
- 9:56shaping and now we have done the
- 9:58irrigation also and now why do we need
- 10:00intal medic so they are used in cases
- 10:03when the poly microbal nature demands
- 10:06the use for example you have weeping
- 10:08canals or the canal is very infected so
- 10:10in that cases you need intra Canal
- 10:13medicament so there are certain ideal
- 10:15requirements of ininal medicaments first
- 10:17of all it should be antimicrobial non
- 10:20iritating and it should remain stable it
- 10:22should have prolong effect and it should
- 10:24be active in the presence of blood
- 10:26seramin proteins and it should have low
- 10:28surface tension should not interfere
- 10:29with the repair and it should not cause
- 10:32training of the to and no cell mediat
- 10:35immune response to be there so
- 10:37indications of the usage as I already
- 10:40said it is used in weaping canals
- 10:42remaining microbes uh removed and in
- 10:45when the root canal contains U
- 10:49inert I mean to render the root canal
- 10:52contains inert and neutralize the tissue
- 10:54TI RIS and as a barrier against the okay
- 10:58so uh
- 11:00history and present so what materials
- 11:02were used in history and what materials
- 11:04are used now so in history Grossman
- 11:07stated the use of
- 11:09PBS C that is P for pencin B for Basin s
- 11:13for streptomycin and C is by which is a
- 11:16vehicle here and he also used pbsn which
- 11:20is neomy and it is an antifungal agent
- 11:23but both of these they have only
- 11:25bacterio static effect therefore they're
- 11:27not recommended now also formal Crystal
- 11:30was used but uh it's now used also by
- 11:34the pedodontist but uh not in endodontic
- 11:37okay and eugenol it is a peric tissue
- 11:40toxin so these two are also not
- 11:43recommended now so what do we recommend
- 11:45now these are calcium hydroxide and
- 11:48chlorexidine digluconate calcium
- 11:50hydroxide and chlorexidine
- 11:54digluconate so calcium hydroxide it was
- 11:57introduced by Herman and the pH of
- 11:59calcium hydroxide is 12.5 and it is
- 12:03because of this pH that it has a bactery
- 12:06cidal effect
- 12:11okay and uh uh it has two properties
- 12:15antimicrobial and heart tissue repair
- 12:18information so how it works it works by
- 12:21releasing uh hydroxy ions which has
- 12:24antimicrobial property so this hydroxy
- 12:27ions they are highly oxidizing free
- 12:30radicals and they will cause a damage to
- 12:33the membrane to the cell membrane and to
- 12:38will cause protein denaturation and will
- 12:40damage the bacterial DNA okay so what it
- 12:43does it does three things damage the
- 12:45membrane protein denaturation and
- 12:47damages the bacterial DNA and the
- 12:49vehicle used is aqu aquar visus or o
- 12:53vehicles and we not use water soluble
- 12:56Vehicles because you have to change the
- 12:58dressing again and again again so
- 13:01examples of Aquas vehicles are Glycerine
- 13:03poly ethylene glycol so um these would
- 13:08need multiple
- 13:10dressing multiple
- 13:13dressing while these can go long without
- 13:17U changing the dressing
- 13:21okay so we often combine uh cmcp with
- 13:25the 0.12% chlorohexidine to get the
- 13:28synergist antimicrobial effect now the
- 13:31next one is Chlor hexagen digluconate
- 13:33and it is effective against eales and
- 13:36canid alicin so it is used both as an
- 13:39irrigant and as inra Canal medicament
- 13:42okay so for the medicament you need 2%
- 13:44uh it is available as 2% CH G and a
- 13:49mixture of CHX and calcium hydroxide now
- 13:52we come to temporary filling materials
- 13:54these are Cav and irm and um generally
- 13:57when we do temporary filling the
- 13:59dressing has to be renewed within a week
- 14:01okay so because what happens is um these
- 14:06dressings they become diluted with the
- 14:10per radical oxidate and they decomposed
- 14:12by interaction with the microorganism so
- 14:15we need to change it so the temporary
- 14:17filling material they should be uh
- 14:19impervious to the fluids they should
- 14:21provide hermetical seal and uh no
- 14:24pressure in the dressing and they should
- 14:26Harden with within minutes and and uh
- 14:29should be able to wear uh the
- 14:32masticatory forces and they should be
- 14:36easy to manipulate
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