E103: Tech layoffs surge, big tech freezes hiring, optimizing for profits, election preview & more — Transcript
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- 0:00what the f what are you wearing Jason
- 0:02what oh Uber had a big week so this is
- 0:05the Uber Montclair crossover hat oh look
- 0:07at that all right and I also bought a
- 0:08Montclair shirt you bought that or I
- 0:10sent it to you oh what oh you got the
- 0:12watch in the mug oh you don't know about
- 0:14the Apple Montclair
- 0:15watch
- 0:18or the commemorative mug
- 0:21or the new tech you don't know about the
- 0:24new neckties that are coming from
- 0:25Montclair it's actually nettec oh my God
- 0:29oh so good I'd just say somebody got
- 0:32their be quiet I'm not saying that I got
- 0:35a hundred thousand dollar sponsorship
- 0:37but we don't have a rule in the
- 0:40agreement about logo placement do we
- 0:43listen Jay Cal if anyone was willing to
- 0:45sponsor you every square inch your
- 0:47clothing will be covered in ads like a
- 0:49race car driver it is look you'd be like
- 0:52wearing a jumpsuit every day you know
- 0:53Montclair sponsorships are great this is
- 0:55five five dollars plus 17 of shipping
- 0:58from France on its Etsy I'm ready to go
- 1:02[Music]
- 1:06Rain Man David
- 1:10said we open source it to the fans and
- 1:13they've just gone crazy
- 1:15[Music]
- 1:18how was everyone's week what'd you guys
- 1:20do this week ah just busy working
- 1:23um trying to be helpful where I can and
- 1:25that'll be the extent of my comments
- 1:27today how is Market Street this time of
- 1:29year look there's all sorts of wild
- 1:30report I've gotten all sorts of inbound
- 1:32from people asking me if I'm like
- 1:34leaving craft Ventures to do something
- 1:35at Twitter no it's not true we're just
- 1:37Jason and I are just pitching in and
- 1:39helping out while Elon establishes his
- 1:41permanent team at that company elon's
- 1:44the CEO he's running it he's the decider
- 1:46he's making the decisions and that some
- 1:48of us are just kind of helping out in
- 1:50any way we can and that's really the
- 1:51extent of it it's a
- 1:53you know very much part-time thing we're
- 1:55just helping a friend but it's been like
- 1:57blown up in by the media into something
- 1:59much more than it actually is it is a
- 2:02hundred percent accurate I am still
- 2:03doing my day job podcasting investing in
- 2:06100 companies a year just helping out on
- 2:08the margins uh that's it the end I do
- 2:10want to try talking about one issue
- 2:12that's already public because it's
- 2:13already been tweeted so Elon had a tweet
- 2:16this morning about how there's now like
- 2:17an Advertiser boycott going on
- 2:21and This falls on the heels of a bunch
- 2:23of reports that came out over the last
- 2:24couple of days that supposedly there's
- 2:26been a big influx of like racist tweets
- 2:30and Jason I actually saw what was really
- 2:33going on which was it's all not true I
- 2:35mean what happened is that within hours
- 2:37of Elon taking over the company on
- 2:38Friday there was a 4chan attack where
- 2:41basically people from this message board
- 2:42created Bots to post hundreds of
- 2:45thousands of spam messages that
- 2:47contained racist words and epithets and
- 2:50within hours this has been detected and
- 2:53Yol who runs the the trust and safety
- 2:55implementation he met with
- 2:58me and Jason and Elon directed him to
- 3:00shut it down and he UL actually posted a
- 3:03tweet story about it that's the only
- 3:04reason I feel comfortable talking about
- 3:05it is because you already
- 3:08posted a tweet storm but maybe people
- 3:09don't haven't seen it or they haven't
- 3:11connected all the Dots here but what's
- 3:13really I think unfair about this is that
- 3:17as you've as you've seen it's not like
- 3:19your feed was all of a sudden filled
- 3:20with racist things these were spam
- 3:22accounts or bot accounts that were
- 3:24posting to zero followers they generally
- 3:26have zero followers or if they do have
- 3:28followers it's other bot accounts right
- 3:30so they're posting racist tweets Into
- 3:32The Ether so to speak it's not degrading
- 3:34anyone's experience it was shut down
- 3:36promptly but then what happens is these
- 3:39activist groups they're monitoring the
- 3:41fire hose right and so they publish a
- 3:43report saying that racist tweets have
- 3:45gone up 500 since Elon took over Twitter
- 3:48the truth is Elon hasn't even had a
- 3:51chance to change anything about the
- 3:53content moderation policies he's posted
- 3:55that like guys I haven't even I haven't
- 3:57changed anything about content
- 3:58moderation whatever the rules are
- 4:00they're the same rules that existed
- 4:02prior to him taking over and this is
- 4:05just an organized operation by people
- 4:08who want to create that report so then
- 4:11these activist groups basically publish
- 4:13this report they feed it to news outlets
- 4:14and then somebody then takes those those
- 4:17reports and then feeds them to
- 4:18advertisers and you get a boycott but I
- 4:20think the point here is that Elon didn't
- 4:23do this this is being manufactured by
- 4:25people who are not operating in good
- 4:27faith they are trying to manufacture an
- 4:29incident that they can then use to hurt
- 4:31the company yeah and it was thwarted
- 4:33immediately and fixed have you guys seen
- 4:35episode 333 of the Lex Friedman podcast
- 4:38he um he interviews Andre carpathy who
- 4:42is really I mean one of the great minds
- 4:44of our of our time particularly around
- 4:46Ai and ML and the question that Lex
- 4:50asked which Andre
- 4:51expounded on which I think is really
- 4:53interesting is
- 4:55what is the next generation of bots look
- 4:57like and
- 5:00I think where the problem gets very hard
- 5:02for all platforms so this is not a
- 5:04Twitter Twitter specific discussion is
- 5:06that you can now generate such real life
- 5:10like human images that are unique and
- 5:13you can also generate high quality text
- 5:16to things like gpt3 that's also you know
- 5:19that can offense essentially push the
- 5:21boundaries of you know a low-level
- 5:24Turing test
- 5:25I think the real problem over time for
- 5:28Bots
- 5:29for spam for coordinated attacks on any
- 5:32platform is that when you use these
- 5:35tools you're going to have to become
- 5:36very sophisticated in how you try to
- 5:39detect them and then to block them it's
- 5:43a really interesting discussion between
- 5:45you know two pretty meaningfully smart
- 5:47people carpathy was the head of uh
- 5:49autopilot at Tesla right autopilot
- 5:52Vision yeah so he's really smart yeah I
- 5:54have no doubt that Elon is going to do a
- 5:57much better job stopping bots on Twitter
- 5:59once he has a chance to do it because
- 6:01he's got this amazing team
- 6:03of AI engineers and and he's just going
- 6:07to be more focused on it you know what I
- 6:08like the most about
- 6:10what I heard this week is the idea that
- 6:12you can do either micro payments or
- 6:14subscription to third-party content
- 6:16providers because I think so much of my
- 6:17news feed is delivered to me through the
- 6:20Twitter app and then I click on an
- 6:22article and then it's like a paywall or
- 6:25it's some sort of difficulty in kind of
- 6:27accessing the content having some
- 6:29integration there or some ability to
- 6:30kind of make a micro purchase to read an
- 6:32article it's going to be I think a super
- 6:35feature the other thing that I would
- 6:36love Twitter to experiment with is if
- 6:38you have a micropayments model to
- 6:40Publishers it would be great if you
- 6:42could publish content without a byline
- 6:44allow The Economist and see what that
- 6:46does to information quality right you
- 6:49know if you if you if you do not get any
- 6:51credit to your individual name for
- 6:54writing stuff but instead it goes to the
- 6:55Masthead publication whatever it is the
- 6:57times
- 6:58the post I think it could have a really
- 7:01important Behavior change in how
- 7:03journalists cover the news it's worth
- 7:05experimenting with at least and if
- 7:07you're paying them enough money I think
- 7:08that you could probably demand that
- 7:10Facebook could probably demand that
- 7:11today you know strip the byline away and
- 7:13just it just says New York Times just
- 7:15like today it just says The Economist
- 7:17yeah it is a um The Economist is a very
- 7:20polarizing gig in journalism for that
- 7:23reason uh there are going to be actually
- 7:25a lot of journalists who would prefer to
- 7:28have their byline taken off one of the
- 7:30problems with journalism today is even
- 7:32if you're doing reporting in good faith
- 7:34tramoth and you put your byline on there
- 7:36harassment you know threats Etc can
- 7:39become very acute if you're just
- 7:40covering certain topics and so I
- 7:42actually think a lot of you know writers
- 7:45and journalists would opt into this they
- 7:46might prefer it I think they should
- 7:48because I think the two ends of the
- 7:49spectrum are better than this you know
- 7:51Gross Middle that we have the end of the
- 7:53spec one end of the spectrum is you have
- 7:55the New York Times The Washington Post
- 7:57and the economists with no byline and no
- 7:59attribution to reporters the other end
- 8:01is if you want to build a brand that's
- 8:03based on your name go start a sub stack
- 8:06yeah and I think that there's a very
- 8:07good balance there and the New York
- 8:08Times could Syndicate that as well but
- 8:10if you separate the two all of a sudden
- 8:12the news becomes more likely to be
- 8:13truthful news versus
- 8:15you know well disguised opinion the the
- 8:19other issue is you know for readers if
- 8:22you do choose to do a no byline
- 8:23publication you're really going to need
- 8:25time to build trust and for people to
- 8:27understand what you're doing because
- 8:28they will think you're taking the byline
- 8:30off in order to pursue a certain agenda
- 8:32right so that is the the that is the
- 8:35suspicion that can build up The
- 8:36Economist has been able to do this over
- 8:37decades with trusted reporting yeah and
- 8:40sub stack proves that you can have no
- 8:42reputation whatsoever and if you're
- 8:43publishing great content you can build a
- 8:45great business from scratch so yeah
- 8:48you don't need to pay your dues quote
- 8:50unquote by getting a byline at the New
- 8:52York Times to be a clever writer
- 8:54you can start that business today and
- 8:56get paid so I think the New York Times
- 8:57should just focus on being the New York
- 8:58Times and sub Stacks should focus on
- 9:01individual people and I think if you
- 9:03could clean up the middle that would be
- 9:05much better for all of us anyways I'm
- 9:07excited for you guys to help out and
- 9:08pitch in I hope you guys do some good
- 9:10with it I'd love to come back and use
- 9:11Twitter more often can we talk about the
- 9:14reporting that happened
- 9:16with the two guys that trolled the
- 9:18journalists and pretended to be fired
- 9:20employees because I actually thought
- 9:21that was such an interesting moment this
- 9:24week that all the journalists
- 9:25immediately parroted it because it fed
- 9:27their narrative Johnson checking done
- 9:30there was no reporting done and then
- 9:32several of them including I think
- 9:33Deirdre Bosa from CNBC came out and
- 9:35publicly apologized for that report and
- 9:38if folks uh listening aren't familiar
- 9:41with what happened these two guys came
- 9:43out they pretended to be fired Twitter
- 9:44employees on Monday walked out with a
- 9:46box
- 9:48up and they were like hey we just got
- 9:50fired it's terrible life is awful no
- 9:51it's even worse husband and wife you
- 9:53know the guy's name was one guy's name
- 9:55is Rahul ligma and the other guy's name
- 9:58was like Mike Johnson so the whole thing
- 10:00was ligma Johnson so I now here's what's
- 10:03so funny about due diligence hold on I
- 10:06read this story without giving away that
- 10:09punch line to my kids
- 10:11all of my kids immediately started
- 10:13howling they're like Dad if you say
- 10:15these two names are ligma Johnson and I
- 10:18was like oh my God and so you know when
- 10:20when like you know pre-teens can figure
- 10:22this out but the journalism industry
- 10:25could not that is kind of a very telling
- 10:27sign Friedberg made the key observation
- 10:28which is they didn't figure it out
- 10:30because they didn't want to because it
- 10:31fit their narrative so they don't they
- 10:32don't fact check things that fit their
- 10:34narrative this was my point about
- 10:36journalism I it just it was so poignant
- 10:38to me this week when this happened
- 10:40particularly as it relates to Twitter
- 10:43and the importance of call it open
- 10:45journalism or citizen journalism and the
- 10:47Integrity of kind of you know of the
- 10:50voices that we all kind of trust as our
- 10:52our kind of journalistic authorities
- 10:53that these guys came out and they were
- 10:55pawned right outside Twitter's offices
- 10:57into telling a story that fit their
- 10:59Sensational narrative and it was really
- 11:01a kind of poignant moment for me well do
- 11:03you remember that story I think it was
- 11:04originally a rolling stone and then
- 11:06Rachel maddowell Amplified it where it
- 11:08was in Oklahoma City where supposedly
- 11:10all these Mega Republicans were eating
- 11:11horse Pace because Trump told them to
- 11:13and they were and this is basically I
- 11:15thought it was like a coveted therapy
- 11:16and then they were going to the
- 11:18emergency rooms of all the hospitals and
- 11:19then they were turning away heart attack
- 11:21victims because there are so many of
- 11:22these these people going to the
- 11:23emergency room anyway it all turned out
- 11:25to be like a made-up story like a hoax
- 11:28but the media reported it because the
- 11:30story was too good right it just it fit
- 11:32too many of their preconceptions there's
- 11:34also one there's another Vector sex
- 11:36which is live coverage is
- 11:39um you know you really have to to be
- 11:41careful because when doing live people
- 11:42will call in and say oh they're at the
- 11:44scene of an accident and then they will
- 11:46do a baba buoy or whatever you know kind
- 11:48of Charades and so without fact checking
- 11:51and without saying hey we haven't
- 11:53confirmed this yet but these two
- 11:55employees are claiming this people want
- 11:57to get real-time coverage it's fine to
- 11:59do real-time coverage I think everybody
- 12:01in the audience has to understand so
- 12:03much credit what about the editor there
- 12:05was a picture and it said ligma Johnson
- 12:12why are you covering for these people
- 12:14I'm not covering I'm just trying to
- 12:16explain it no you're gonna even let me
- 12:18unpack the whole point let me unpack the
- 12:19whole point there's also you interrupted
- 12:21me well here's the thing there is a
- 12:23different standard for live news
- 12:24coverage and then there we've ripped out
- 12:26fact checking from a lot of these
- 12:27Publications and basic fact checking and
- 12:29a little bit of time I'm explaining why
- 12:31they make this mistake I'm not
- 12:32protecting them you want to know the
- 12:34reason they make it that's part of it
- 12:36but they've also ripped out fact
- 12:37checking and then they are in such a
- 12:39race to get the clicks on social media
- 12:41no no here's what's going on if the
- 12:43story fits their priors they run with it
- 12:46immediately and they don't do any fact
- 12:47checking because they don't want to know
- 12:49that it's not true that's what's going
- 12:51on there is an element let's check a
- 12:52story if it's a narrative they don't
- 12:54like because they're gonna they're gonna
- 12:56try and make sure it's not true yeah
- 12:57that's true of both sides and they'll
- 12:58use proxies this thing there's only one
- 13:00mainstream media this is the mainstream
- 13:03media who's the alternative
- 13:06Fox is uh the the number one network the
- 13:09alternative to the number one network is
- 13:11do you think journalists do this tell me
- 13:15the writer tell me the writer on sub
- 13:16stack wow there's a lot of different
- 13:18ones there so I who got fooled what sub
- 13:20stock writer got fooled by ligma Johnson
- 13:28fooled by ligma Johnson I don't think so
- 13:31I'm not defending don't make me just
- 13:33defend ligma I'm not defending we are
- 13:37both sidesing it I'm not both sizing it
- 13:38I'm telling you what is happening in
- 13:40journalism today they have ripped out
- 13:42fact checking and they are in a race to
- 13:44beat each other because the first person
- 13:45to get the story up gets a clicks that's
- 13:47the dysfunctional thing they try to
- 13:49create a story when there was no story
- 13:50there they agree with that as well they
- 13:53went and camped out outside of an office
- 13:54mid-market Street yes and they said hey
- 13:56there's this Sensational thing happening
- 13:58and there was no Sensational thing
- 14:00happening correct and so the little drop
- 14:02that fell into their laps the little
- 14:04thing that fell into their laps became
- 14:06the story because that's the story they
- 14:08wanted to see created there was no story
- 14:09beforehand that then that there were all
- 14:12these people being fired walking out
- 14:13with boxes and then they said let's go
- 14:14send live TV producers down there they
- 14:16sent the live TV producers down there
- 14:17and then the same things
- 14:20they did the same thing in New York at
- 14:23Bears to read the cover when they had
- 14:25other major layoffs at Bear Stearns and
- 14:27stuff like that during the financial
- 14:28crisis of course they sent people to do
- 14:29live coverage there not defending it I'm
- 14:31just explaining to you what's going on
- 14:32in the background as well with live TV
- 14:34and and the gutting of newsrooms and
- 14:36having no fact checking a lot of these
- 14:37stories go out but what about 20 years
- 14:39ago my 11 year olds and 10 year olds
- 14:43better copy editors than these adults at
- 14:46these that's crazy incredible
- 14:48Publications my kids started howling
- 14:50they were like Dad do you understand
- 14:52what you just said there's a league
- 14:54budget yeah I mean awesome I mean come
- 14:56on this is like prepubescent humor that
- 14:58these people fell for it it's ridiculous
- 15:01it's embarrassing it's certainly
- 15:02embarrassing yeah it is embarrassing and
- 15:05this connects with the 4chan board it's
- 15:06the same problem this is a grievance
- 15:09industrial complex right they're
- 15:11manufacturing grievances it's funny in
- 15:14the case of ligma Johnson it's not funny
- 15:16in the case of the 4chan board but these
- 15:18are people who are inventing stories
- 15:19because
- 15:21yeah to manipulate media because they
- 15:23know it's so easy to manipulate the
- 15:25media right anyways big shout out to
- 15:26Rahul ligma that was a great stunt well
- 15:29played sir it happens to be a huge fan
- 15:31of the all-in podcast apparently sir
- 15:33come on as the bestie guesty anytime he
- 15:35wants oh no well no definitely not
- 15:37please all right we should talk about
- 15:39layoffs and Tack lift 13 riff 700
- 15:43employees let go yesterday
- 15:45stripe 14 riff a thousand employees open
- 15:48door chime Dapper Labs all hundreds of
- 15:51employees Open Door the most significant
- 15:53they're 550 18 percent
- 15:56Dapper 22 percent uh and Twitter we'll
- 15:59see what the Riff winds up being but
- 16:01that's occurring as we're taping here so
- 16:02and then Jason Apple did a pause Amazon
- 16:05did a pause
- 16:07right and Google and Facebook
- 16:10yeah maybe trying maybe signaling a
- 16:14pause but haven't they've been hiring
- 16:15like in absolutely uh at a crazy crazy
- 16:19pace and we'll pull up the chart here
- 16:20actually it's instructive to look at
- 16:22Facebook and Google because they have
- 16:24not slowed down by any stretch of the
- 16:26imagination
- 16:28just by the raw numbers uh this all
- 16:30started to Peak in June and now it's
- 16:33starting up again so there's a website
- 16:35uh layoffs.fyi that's been tracking all
- 16:38these layoffs you can see the number of
- 16:40layoffs these are kind of major layoffs
- 16:42and the number of employees impacted
- 16:44been pretty consistent in the third
- 16:48quarter it started to die down in
- 16:49September
- 16:51from the Peak in May and June and now
- 16:55right yeah it feels like this is the
- 16:57double dip we were talking about I think
- 16:59this is the beginning this is not even
- 17:01unpack it well I think that we had if
- 17:03you take a very balanced view of what
- 17:04happened this week
- 17:06you have to start I think with the
- 17:08Federal Reserve and really what they
- 17:10said is rates will probably be higher
- 17:13than all of you think
- 17:14and they'll be higher for longer than
- 17:16all of you want
- 17:18and again without debating whether you
- 17:22know that's going to come to pass or not
- 17:24the thing that you can do is you can
- 17:26build a little sensitivity model to
- 17:29understand the mathematical implication
- 17:31of it and basically what it means is
- 17:33that the dollar that's right in front of
- 17:35you
- 17:36is now meaningfully more important than
- 17:38the dollar that's far far away from you
- 17:40so let's just assume
- 17:43that you know the FED funds rate goes to
- 17:45five and a half percent or so
- 17:47even five let's let's go to the
- 17:49optimists and say it's only going to go
- 17:51to five
- 17:52tech companies have to achieve 500 basis
- 17:54points above that minimum
- 17:56so we all have to generate 10 to 11
- 17:58percent returns for us to be on a
- 18:00risk-adjusted basis better than a
- 18:03Government Bond
- 18:05the problem with that is all of a sudden
- 18:06you know if you're trying to generate
- 18:08cash even three or four years from now
- 18:11it's not worth that much you need to
- 18:13generate dollars today and so you know
- 18:16they are really re-prioritizing the
- 18:19value of short-term profits and that's
- 18:21going to affect how companies get money
- 18:24the cost of capital so how much dilution
- 18:26you have to take so I think this is what
- 18:29companies are now bearing down for
- 18:31they're realizing oh man I need to get
- 18:34my cost structure way in line it is way
- 18:37better now just to put think about this
- 18:39contrast it's way better to grow at 20
- 18:41and be profitable
- 18:43than it is to grow at 100 and burn money
- 18:45because it's not clear where that second
- 18:47company is going to get the incremental
- 18:49dollars they need for growth and that's
- 18:51just a mathematical realization when
- 18:53rates are five percent risk-free rates
- 18:55are five percent so I think this is this
- 18:56is that moment where you see that pivot
- 18:58from pivot growth to profit yeah yep
- 19:01we've been talking about it for six
- 19:03months but this is this is this is how
- 19:06it is Manifest in Silicon Valley
- 19:08companies is of scale is through layoffs
- 19:11and cost reductions and cost savings
- 19:14so the investments in future growth are
- 19:17reduced and the timeline to drive
- 19:20greater profits
- 19:22is improved I think what if what Elon is
- 19:25going to do at Twitter
- 19:27or what is reported so this is nothing
- 19:29to do with anything anyone told me just
- 19:31what I've read in the reporting
- 19:33it's accurate that he's going to cut so
- 19:34deep he's going to cut 30 40 50
- 19:36potentially of the employee base
- 19:39it really sets a new standard for how
- 19:42profitable a tech company can get and
- 19:44again I'll give credit to a Twitter
- 19:46poster named post Market who I didn't
- 19:48give credit to a few weeks ago when I
- 19:50read this tweet
- 19:52which I think was a good one which was
- 19:54that elon's really going to show
- 19:55everyone just how profitable these tech
- 19:58companies can be just how lean they can
- 19:59be run
- 20:01and you know when you're doing a 10 riff
- 20:03or a 13 riff you may or may not even be
- 20:06getting to profitability with that riff
- 20:08when you cut 30 40 50 deep and you can
- 20:12actually turn a real profit on a
- 20:14business an Enterprise scale business
- 20:15like a Twitter or like many other
- 20:17enterprise software companies that are
- 20:19out there right now
- 20:20it really kind of sets a new standard
- 20:22that a lot of folks might then end up
- 20:23saying you know what maybe we should go
- 20:25deeper and there could be the case that
- 20:28private Equity firms take a look at this
- 20:29and there's a lot of these distressed
- 20:31mid cap and small cap software companies
- 20:33out there that private Equity firms now
- 20:35realize wow you don't actually need 50
- 20:38of the workforce in order to keep the
- 20:41product running and to drive to
- 20:42profitability and you could see a bit of
- 20:44a flurry of buyout activity
- 20:46as more folks come in and maybe try and
- 20:49mimic the Elon Playbook so you know
- 20:52that's one kind of prediction I think
- 20:54may arise if Elon is successful in
- 20:56making Twitter a much more profitable
- 20:58Enterprise it could set a new model that
- 21:01catalyzes a lot of other M A activity a
- 21:03lot of other buyout activity of these
- 21:05distressed small and mid-cap companies
- 21:06uh by uh by other actors can I build on
- 21:09what you're saying Nick could you please
- 21:10just
- 21:12throw up that tweet that I sent just for
- 21:14all of these guys to look at because I
- 21:15think it's incredible so to your point
- 21:16this is an incredible uh slide just an
- 21:19incredible slide and essentially what it
- 21:21shows for those folks that are not
- 21:22watching this on YouTube is it
- 21:25essentially shows the private software
- 21:27universe and then the public software
- 21:30Universe at different levels of
- 21:32valuation so as an example right now
- 21:35there are 15 companies private companies
- 21:38that are valued greater than 10 billion
- 21:40dollars
- 21:41and there are 40 public ones that are
- 21:43valued greater than 10 billion there are
- 21:4550 companies between you know
- 21:48more than 5 billion but only 60 that are
- 21:52public that are valued more than five
- 21:53and here's what's crazy there are 400
- 21:56companies
- 21:58who have an average valuation of 3
- 22:00billion
- 22:01and then there are already 70 companies
- 22:04in the public markets where they have a
- 22:06billion dollars of next 12 months of
- 22:09Revenue and it just goes to show you to
- 22:12your point freeberg
- 22:13if these folks have to generate an 11
- 22:16hurdle rate their cost of capital is 11
- 22:19percent
- 22:21the companies on the left will have to
- 22:23go through a lot of very difficult cost
- 22:26cutting potentially head count
- 22:27reductions
- 22:29you know repricing of the product
- 22:32all kinds of things
- 22:33yeah no not none of them have oh of
- 22:37these many of these are the left tracker
- 22:39you're on the Left Right 400 there
- 22:41there's almost 500 companies here that
- 22:43have to do an enormous amount of work so
- 22:45that they have a chance to be on the
- 22:46right hand side of this chart the point
- 22:49is that you didn't have to do this when
- 22:51rates were zero there was just an
- 22:53abundance of free money and risk seeking
- 22:55and duration
- 22:56that is now out of the market I think
- 22:59there's also a story that of the 200
- 23:01companies that are software public
- 23:03software companies that you see on the
- 23:04right
- 23:05some number of them will need to go
- 23:07private in order to do the restructuring
- 23:09that the market is demanding that they
- 23:10do in order to get rightly valued and to
- 23:13your point it will happen at
- 23:14meaningfully lower valuations than where
- 23:16they probably went public or their last
- 23:18drive around which will you guys as you
- 23:21guys enormous instructions yeah if you
- 23:23guys look at these 200 companies on the
- 23:24right how many of them do you think go
- 23:26private over the next 18 months to get
- 23:28restructured Allah what Elon is showing
- 23:31everyone is possible on Twitter 18 is 18
- 23:34months is hard to predict but to your
- 23:35point Freeburg I think if you look at
- 23:37the number of them that are unprofitable
- 23:40at least half of them will have
- 23:42difficulty and about so I think about
- 23:44two-thirds of these companies really
- 23:46have no line of sight to profitability
- 23:48in the next two to three years and again
- 23:50if you if you layer in this cost of
- 23:52capital argument
- 23:54all of those companies David will have
- 23:56to raise money at very egregious terms
- 24:01in order to keep themselves going as a
- 24:03public business in which case their
- 24:05alternative is to go private in a PE
- 24:07transaction so it's probably at least
- 24:10half these businesses I mean it's a lot
- 24:12there's 100 PE deals to be done yeah 100
- 24:15wow Stacks what do you think
- 24:17because you know these businesses and
- 24:19the models I mean some of them it's hard
- 24:20to get profitable if you're a scaling
- 24:22SAS business right like you have to get
- 24:24to a certain scale before it's possible
- 24:26well I don't I don't that's like a very
- 24:28specific question of like how many of
- 24:30them are gonna get acquired by pe firms
- 24:32versus going public or going private
- 24:35after being public that's that's like a
- 24:37very specific question I think the
- 24:38larger point is just that it feels to me
- 24:41like the economy is headed off a cliff
- 24:42right now I mean I can tell you within
- 24:44our larger portfolio of companies
- 24:48like I can see the trajectory so after
- 24:50q1 board meetings I would say about
- 24:53two-thirds of portfolio companies were
- 24:55hitting their numbers and one-third were
- 24:57missing and it still appeared to be like
- 24:59problems related to those specific
- 25:01companies not a macro Trend I would say
- 25:04after Q2 board meetings two-thirds were
- 25:06missing and one-third were hitting their
- 25:08numbers and it you could start to feel
- 25:09okay maybe there's like a macro Trend
- 25:11here and I would say after
- 25:13Q3 board meetings like now
- 25:15the entire portfolio is is reforcasting
- 25:18uh maybe there's like a handful of
- 25:20companies here or there that aren't if
- 25:22you're one of those congratulations but
- 25:24like even the best companies our
- 25:26portfolio now are seeing major headwinds
- 25:28and this is just I think an economy-wide
- 25:30slowdown do you think there's
- 25:31restructuring possible I mean can these
- 25:33companies yeah because let me just ask
- 25:36in the public markets do you think those
- 25:37public companies can get restructured as
- 25:40public companies in order to yeah it
- 25:42just yes it will yes of course it is
- 25:44extremely expensive well it's expensive
- 25:46I don't even think it's will I think
- 25:48it's just expensive
- 25:49yeah I mean coinbase as an example like
- 25:51look take coinbase versus carvana right
- 25:54these are both businesses that issued
- 25:58convertible debt sort of right before
- 26:00things got very very hard and if you
- 26:02look at where their convertible debt
- 26:04trades it's trading basically at an
- 26:06implied yield of about 12 or 13 both
- 26:08companies now one is probably you know a
- 26:12legitimate bankruptcy risk which is
- 26:14carvana that's what the market would
- 26:15think whereas the other one you know I
- 26:17think it has a very fortified balance
- 26:19sheet and could weather the storm
- 26:20coinbase but unfortunately in a moment
- 26:23where you know rates are again the
- 26:26risk-free rate goes to five five and a
- 26:28half our cost of capital to do business
- 26:30goes to 10 or 11. these guys have to pay
- 26:3312 or 13 my gosh it's really really
- 26:36deluded to be in business right now so
- 26:39it just goes to show you that you can
- 26:41stay public but if you want to get
- 26:44incremental money to cover your burn the
- 26:46only way you can do it without really
- 26:48you know blowing up your cap table and
- 26:50doing a massive recap
- 26:52will be through convertible debt but it
- 26:55has a huge overhang and you risk turning
- 26:58the keys over to the debt holders of the
- 27:00company
- 27:01so the alternative for that business is
- 27:03to go into the hands of private equity
- 27:06and get out of the spotlight of these
- 27:08public markets but public private Equity
- 27:11is very smart and the thing that's
- 27:14happened to them is they can't raise
- 27:16debt
- 27:17right so what do you think they do they
- 27:18just have to pay 50 less than what they
- 27:20would be willing to pay before because
- 27:21they have to write you know 100 Equity
- 27:24check so right there is no free lunch
- 27:27anymore I think is the big is the big
- 27:29point to to point out anywhere in the
- 27:31market right now I think one of the
- 27:33things I'm most concerned about or would
- 27:35be is I was talking with a friend who
- 27:37works at a private you know unicorn
- 27:40software company any we talked about the
- 27:43numbers of the business and I was like
- 27:44oh that company's probably worth X and I
- 27:46gave him a number and then I asked him
- 27:48how much money they've raised and
- 27:49they've raised more than x so I was like
- 27:52dude your options are worthless like you
- 27:54know this is a real problem I think
- 27:56that's probably going to become very
- 27:57systemic
- 27:58for scaled unicorn software companies
- 28:01what happens to these businesses sacks
- 28:02in the market
- 28:04you know as they kind of need another
- 28:06round but the value of the company is
- 28:08now less than the total cash that
- 28:09they've raised that all is sitting as
- 28:10preferred stock
- 28:12listen it's it's survival of the
- 28:14quickest those who are most willing to
- 28:17adapt the most quickly are going to
- 28:19survive and the ones that are stubborn
- 28:20and refuse to accept the new regime the
- 28:23market regime are gonna die we showed
- 28:25that chart remember that chart from
- 28:26Sequoia months ago on this podcast
- 28:29remember that where it basically showed
- 28:31what happens if you're a company that
- 28:34doesn't cut burn until the very end then
- 28:36you're still going to run out of money
- 28:37and die but if you make the cut right
- 28:39away quickly you you have enough Runway
- 28:42to weather the storm and I think that
- 28:44what we've seen is you know at my firm
- 28:47craft yeah this is exactly it yeah we
- 28:49showed This months ago we've been
- 28:50begging our Founders to embrace this we
- 28:52did a portfolio a review with our entire
- 28:56set of founders of our portfolio
- 28:58companies we did one in February when we
- 29:00felt the markets were changing and we
- 29:02did another one in May and we showed the
- 29:04slide and this is the most important
- 29:06thing for Founders to internalize is you
- 29:08have to make the changes quickly you
- 29:10know one way for them to think about it
- 29:12is let's say say you're a unicorn
- 29:13company okay and you raised at the peak
- 29:16let's say second half of 2021 you raise
- 29:18100 million dollars at a billion dollar
- 29:20valuation and let's say you've got 50
- 29:22million left in the bank right so you've
- 29:23burned 50 million a lot of these
- 29:25Founders are thinking that 50 million
- 29:27they've got left is only 5 dilution but
- 29:29that's what it was historically if you
- 29:31were to raise a new round today you
- 29:33might only be valued at 250. so that 50
- 29:36million you have left is actually 20
- 29:38dilution and that's if you could even
- 29:40raise which might be very very hard the
- 29:43most important thing Founders can do is
- 29:44forget about the historical terms on
- 29:47which you raise that money forget about
- 29:49how much money you were burning in the
- 29:51past just think about how much money you
- 29:53have in the bank today impute evaluation
- 29:56to it so you really internalize how much
- 29:58dilution that money represents and then
- 30:01create a new plan moving forward to
- 30:03preserve that cash as long as possible
- 30:04can I say something else quickly on top
- 30:06of this that's I think that's really
- 30:07good advice
- 30:10the thing that again people should do is
- 30:12you should just build a little
- 30:14spreadsheet for yourself to understand
- 30:16what the alternative financing options
- 30:19are for people who are in the business
- 30:21of investing so David to your point the
- 30:23current three-month t-bill rate is four
- 30:26percent
- 30:26you know you can buy munis now between
- 30:28four and five percent that are that are
- 30:31Triple Tax advantaged right you can buy
- 30:33uh high quality corporate bonds that are
- 30:36six seven eight percent
- 30:38and so it's stocks that have a dividend
- 30:40yield of five percent of growth growing
- 30:43Market leading growing and so all of
- 30:45them dividend yield exactly and so all
- 30:48of a sudden like turning around and
- 30:49giving it to a company where there is no
- 30:51end in sight in terms of it doesn't get
- 30:53you to profitability
- 30:55is a really really hard thing to do I
- 30:57was talking to an entrepreneur David
- 30:59soloff just yesterday
- 31:01and he said it really well he's like
- 31:04listen you know I'm not a macro
- 31:06Economist I'm not trying to forecast but
- 31:07he's like what I
- 31:09understood yesterday this is David
- 31:11talking about the FED as an entrepreneur
- 31:13the angle of attack has changed the FED
- 31:16has said this is not going to be some
- 31:19triangle Sawtooth it's not going to go
- 31:21up sharply and then come back down
- 31:23sharply which is what we would all want
- 31:26if we wanted things to get back to
- 31:28normal sooner
- 31:30the angle of attack is now a little bit
- 31:32slower which means it's going to take
- 31:34longer to get where we need to be
- 31:36and then we're going to stay there for a
- 31:37lot longer than we want and when you
- 31:39roll those two things together a lot of
- 31:42companies may run out of money
- 31:44and so if you can't get to default alive
- 31:46you have to look at your cost structure
- 31:48and figure out how to right size this
- 31:50thing because
- 31:51the cost of capital is just going to be
- 31:54really really expensive and this was the
- 31:56fed's goal right they wanted to take
- 31:57away this free Capital they want to slow
- 31:59the economy down and it seems like
- 32:01they're making progress they did the 75
- 32:03basis point
- 32:04hike this week but
- 32:06we're adding jobs to the economy we have
- 32:08more job openings and we had 2.6 percent
- 32:11GDP growth so I guess my question to the
- 32:13to everybody here is
- 32:15what is the Fed gonna have to do or can
- 32:18they stop this consumer and this growth
- 32:22it's very strange right Powell Powell
- 32:24said he'd rather over correct
- 32:27and break things because he has a
- 32:29toolbox to fix the broken bones but he
- 32:32doesn't have a toolbox to fix if they
- 32:34under correct and they have rampant
- 32:36inflation
- 32:38I mean not more explicit you can't get
- 32:40Jason so he's going to take rates until
- 32:42demand is destroyed and enough demand is
- 32:45destroyed such that inflation is tamed
- 32:48but that has huge implications to all of
- 32:50us because we all have to do our job
- 32:52trying to build a company trying to
- 32:54raise money trying to invest money
- 32:56it's just getting much much much harder
- 32:59than I even thought so like you know for
- 33:01me I'm like wow I thought that we could
- 33:04get through the worst of this by mid-23
- 33:06but now you have to plan for the worst
- 33:08which means okay now I'm thinking that
- 33:10man rates could be higher for much
- 33:13longer which means you know we could be
- 33:14in this market until early 25 and you
- 33:17may say hey that's way too conservative
- 33:20yeah but you have to plan for
- 33:22conservatism in this point so how do I
- 33:24invest money right now honestly I'm like
- 33:27hmm I should just put more into T bills
- 33:29isn't that crazy if a company's like
- 33:31hmoth can have another 10 15 20 million
- 33:33bucks I'm like wow I mean I don't think
- 33:35that that gets you anywhere and oh by
- 33:37the way that 10 or 20 million dollars I
- 33:39can generate four percent
- 33:40what a what a tough trade-off right for
- 33:43well for somebody who has access to
- 33:44private markets which should be high
- 33:46growth companies to take the guaranteed
- 33:48four over the 50x 25x10x whatever we're
- 33:52trying to bet on here yeah that's not
- 33:54it's not just the guaranteed four but if
- 33:56you want to take Tech risk then you
- 33:58could go buy the corporate bonds of some
- 34:00high quality companies for the 10 or 11
- 34:01so you take moderate risk so you're also
- 34:03competing with that not to zero risk can
- 34:05you explain that for the listeners what
- 34:06that corporate debt is and why it you
- 34:08know pays more sure there are there are
- 34:10you know high quality public companies
- 34:12tech companies that have bonds and
- 34:14that's corporate debt and they obviously
- 34:16have to pay a higher rate than what the
- 34:18treasury pays because the treasury is is
- 34:21risk-free and corporations could default
- 34:23so there is some risk to it it's not
- 34:25zero risk but you know it's like if
- 34:27you're willing to take Tech risk then
- 34:29why wouldn't you buy a bond at 10
- 34:30meaning the equity always has to beat
- 34:32that threshold return but but hey can we
- 34:36just go back to the jobs report for a
- 34:37second I mean the U.S government could
- 34:39default but it's considered the least
- 34:41likely to default of all issuers of debt
- 34:44in the world and that's right
- 34:47yeah that's why people call it the
- 34:49risk-free rate because it is the least
- 34:51risky the U.S can always repay its debt
- 34:53because the debt is denominated in
- 34:55dollars and the treasury can always at
- 34:57the end of the day print more money that
- 34:58would just be monetizing the debt other
- 35:00countries that owe money in dollars and
- 35:03obviously don't control the U.S mint
- 35:05they can't do that so they could
- 35:06actually default but since we're the
- 35:08world's Reserve currency we're never
- 35:10going to default however the dollars
- 35:12that you get paid back by the US
- 35:14government might be worth a lot less in
- 35:16the future because of inflation and
- 35:17that's the real risk you have to think
- 35:19about but there's no default risk right
- 35:21whereas with corporate debt there is but
- 35:23let's just go back to this the Jaws
- 35:25picture for a second Jason you asked
- 35:27about this so there is news this morning
- 35:30that we added 261 000 jobs in October
- 35:32and obviously given that there's an
- 35:33election in a few days then you know the
- 35:36administration is eager to point to this
- 35:38but if you dig a little deeper in the
- 35:40report I just posted the link there you
- 35:42see in the Raw numbers that there's
- 35:43actually 328 000 fewer employed
- 35:47Americans and the number of unemployed
- 35:50Americans actually increased 36 000. so
- 35:53and the labor force participation rate
- 35:55declined for the Third
- 35:56consecutive month to 62.2 percent so
- 36:00like I don't really understand like how
- 36:02all these numbers add up but the point
- 36:03is like the data is very mixed our new
- 36:06and and this very definitely negativity
- 36:08in there
- 36:09and this feels to me like the last gasp
- 36:12of the bull market where there's like
- 36:14this residual job creation but you look
- 36:18at like just what's happened in the last
- 36:19week where it's stripe cutting I mean
- 36:21Stripes probably the single highest
- 36:24quality I think it's probably the most
- 36:25valuable private company
- 36:29okay but but like software pure software
- 36:31company they had a 14 cut you're
- 36:33starting to see now the riffs really
- 36:35start to pile up so I think we're at the
- 36:38beginning now of a long cycle of the
- 36:41unemployment rate going up I mean it
- 36:42just feels like the economy is slowing
- 36:45so fast the markets are you know they've
- 36:48been puking now for six months it just
- 36:51feels like this is the beginning of a
- 36:53like really serious recession yet we had
- 36:54GDP growth yet we had job uh openings we
- 36:59had two quarters we had two quarters of
- 37:00net negative GDP growth this is when we
- 37:03had the debate about what our recession
- 37:04is it was true that if you looked at
- 37:07growth in nominal terms that appear to
- 37:09be strong and then it was net negative
- 37:11once you subtracted the inflation rate
- 37:12you know we said several months ago my
- 37:15prediction was a double-dipper session
- 37:16where you had this shallow technical
- 37:18recession then it bounced back in Q3 but
- 37:21now I think we're headed into the second
- 37:23part of it which is the real recession a
- 37:24recession characterized by joblessness
- 37:26and you're starting to see economists
- 37:28say we're going to go from three point
- 37:29something percent unemployment rate to
- 37:31say five or six percent unemployment
- 37:33next year so I think we're just
- 37:36beginning to see the the job Cuts start
- 37:38to add up
- 37:39this is I think this is what Powell met
- 37:42which is you know he'll take it as far
- 37:44as it takes and then he can fix it on
- 37:46the back end by reintroducing
- 37:48you know quantitative easing and
- 37:50reintroducing lower interest rates to
- 37:52stimulate demand
- 37:55but there's what are the odds he gets
- 37:57this right it seems to me that the FED
- 37:59has a habit of reacting too slowly they
- 38:01were too slow to react to inflation my
- 38:05guess is that they'll be too slow to
- 38:06react to the recession so we'll end up
- 38:09with a period of rates being higher than
- 38:11they should too long and then they will
- 38:13correct they'll drop rates but that
- 38:15could be two years from now and
- 38:16meanwhile we could be in a pretty deep
- 38:17recession two charts for you to look at
- 38:20the GDP uh by quarter and then after
- 38:23that the labor participation rate so
- 38:26there's your GDP q1 Q2 being negative Q3
- 38:29bouncing back we'll see what happens in
- 38:30Q4 here's your fed Force participation
- 38:33rate for labor as we discussed the thing
- 38:36with the labor participation rate that
- 38:37we're still not sort of like truly
- 38:39factoring in is like you know we had a
- 38:40million Americans die because of covid
- 38:42and you know starting in that Trump
- 38:45presidency we lost like seven or eight
- 38:47million immigrants
- 38:48so those eight million people have a
- 38:50huge effect on this number yeah right
- 38:52and it's not properly really factored in
- 38:54because if if you see that at the start
- 38:56of the Trump presidency it's just it's
- 38:58it just fell off a cliff basically
- 39:00and you also have people who retired
- 39:02early that was a big Trend and this all
- 39:04peaked in 2000 labor participation
- 39:06hitting that like 67 68 I think it's the
- 39:09peak
- 39:11and just slowly going down as Boomers
- 39:13retire early because they made so much
- 39:15on their 401ks and homes
- 39:17and then you're right your mouth we've
- 39:19had negative we've really cut
- 39:21immigration in the last whatever five
- 39:22six years I think there's an element in
- 39:24here that's missing on how much people
- 39:27individually are finding other ways to
- 39:29earn income that doesn't qualify and
- 39:31show up in the labor force numbers
- 39:33people
- 39:35have set up Etsy stores Shopify stores
- 39:38have tripled since covid
- 39:40people are making more money on YouTube
- 39:42on Instagram on Tick Tock than ever
- 39:45before there's a whole new class of work
- 39:47that revolves around the individual
- 39:50creating their own business creating
- 39:53their own income stream
- 39:54that's simply taken off
- 39:56and have taken off it was it was kind of
- 39:58a trend pre-covered but it really took
- 40:00off during covid and there's an element
- 40:02of this that's really more about the
- 40:04transition of how people work and how
- 40:05they earn
- 40:06that isn't reflected in these numbers I
- 40:08don't think that the idea that everyone
- 40:09should go be an employee at a company is
- 40:12necessarily the right way to think about
- 40:13Labor going forward the amount of money
- 40:16that individuals are earning is probably
- 40:18the better way to frame this up going
- 40:20forward and as really thinking about the
- 40:22earning power and the economic health of
- 40:24this country
- 40:25this is something important you're
- 40:26bringing up here gig workers are about
- 40:28nine percent of the uh Workforce and uh
- 40:31Uber and Dara had um
- 40:33they they grew over 70 this year but I
- 40:36think the big number that I watched for
- 40:37was drivers are making 36 dollars an
- 40:40hour in the United States working for
- 40:42Uber so you're exactly right people are
- 40:43finding other options whether it's
- 40:45doordash or Uber and that doesn't
- 40:46qualify in labor force right because
- 40:48they're no contract independent
- 40:51contractors are counted yeah they are
- 40:52counted I that's based on my preliminary
- 40:55research if somebody wants to fact check
- 40:56us that'd be great but my understanding
- 40:58is independent contractors which is what
- 41:00gig workers are classified under are
- 41:02counted in labor participation I don't
- 41:04know how they're counted so uh we'll
- 41:06we'll look that up and figure that out
- 41:09there was a story in BBC that the bank
- 41:12of England has now warned that the UK is
- 41:14facing its longest recession since uh
- 41:17Records began some of this is getting to
- 41:19be fear porn yeah but look here's what I
- 41:23think is scary about going into a
- 41:24recession is number one you don't really
- 41:26know how long it's going to take to get
- 41:27out we know the average recession lasts
- 41:29about 18 months but the truth is once it
- 41:31starts you just don't know and the
- 41:32second thing is you don't really know
- 41:34who's been stress tested people claim
- 41:36that they can weather the storm but the
- 41:38truth is that there's no there's no way
- 41:41to simulate truly simulate a stress test
- 41:43they claim they can but the only way is
- 41:46to really subject you know an
- 41:48institution to that pressure and that
- 41:49stress and then you see if they come out
- 41:51the other side so that's the issue is
- 41:53you're just going into this it's there's
- 41:55there's all there's a lot of unknown
- 41:57unknowns and
- 41:58and this is why I would just urge
- 42:00Founders to be cautious is because if
- 42:03the recession ends up being shallower
- 42:04and shorter than people expect great
- 42:07you'll be surprised to the upside but if
- 42:09the recession ends up being deeper and
- 42:11and longer than expected you don't want
- 42:13to go out of business you want to be
- 42:14protected against that so again you know
- 42:17we've been saying this since February
- 42:18and may but again I just reiterate I
- 42:20think it really makes sense for Founders
- 42:22to be conservative prioritize your
- 42:26survival above all else you know this
- 42:29recession probably will last about two
- 42:30years you want to make sure you survive
- 42:32it and to shama's point if you survive
- 42:34it with lower growth that's fine you can
- 42:36keep growing on the other end of this
- 42:37thing but if you go out of business
- 42:39because you grew too fast then you're
- 42:41not going to get the chance to fix that
- 42:42problem when the recession is over I
- 42:45just don't see anybody rewarding hyper
- 42:48growth that is burning a ton of cash
- 42:50where you have to be back in Market
- 42:52every year
- 42:53because it's it's just very hard to feel
- 42:56comfortable that the conditions on the
- 42:59field aren't going to be drastically
- 43:01different a year from now right it's not
- 43:02like we know that it's going to be
- 43:04better or worse and I think that that
- 43:07uncertainty is actually really bad for
- 43:09companies so to your point it's just
- 43:11like
- 43:12a lot of folks have tried to shy away
- 43:14David from actually revisiting their
- 43:16valuations they've done these
- 43:18complicated converts and they've tried
- 43:20to basically you know
- 43:23it's I think it's sort of like managing
- 43:25their ego or the board's ego and I think
- 43:28like the next shooter drop has to be
- 43:30these Founders and these boards just
- 43:33saying okay let's just take the hard
- 43:34medicine what's the real you know market
- 43:36clearing price and valuation let's get a
- 43:38third party to price it and let's get
- 43:40new fresh equity and then move forward
- 43:41because if you don't do that and you
- 43:44wait until everybody's trying to do it
- 43:46then it's going to be a really tough
- 43:47scenario so better to your point you
- 43:50know this is why I like stripe it's so
- 43:52smart better to cut now
- 43:54again it's always hard to let people go
- 43:56but it's better to do that now than 18
- 43:59months from now because you just have no
- 44:02idea how much more expensive or hard
- 44:04it's going to be then
- 44:06and who's going to even be in the
- 44:07business of lending money or investing
- 44:09money in 18 months
- 44:10and you know that that sounds pretty
- 44:12crazy but it's it's like I think that
- 44:13that's that's the moment that we're in
- 44:15to your point uh Friedberg I did a
- 44:17little research here and um
- 44:19according to the FED of St Louis if you
- 44:22accounted
- 44:24uh casual workers informal workers
- 44:28over doing over 20 hours a week of
- 44:31informal work AKA gig work you would
- 44:33increase labor participation between a
- 44:35half point and a point if you counted
- 44:37all of them maybe even uh slightly more
- 44:40than two percentage points higher so
- 44:41probably about a point uh seems like a
- 44:43realistic way to look at Labor
- 44:45participation and of the eight points or
- 44:48maybe now the six or seven points the
- 44:50ten percent
- 44:51it would then account for 10 to 20 of
- 44:53the 10 drop in labor participation it's
- 44:57just alarming statistics because if most
- 44:59people have most of their
- 45:02personal net worth tied up in their home
- 45:04asset and their home values are
- 45:06declining are going to decline
- 45:09and we're seeing this dramatic spike in
- 45:11Consumer Credit in the U.S it paints a
- 45:14really ugly picture for the next two
- 45:15years wow guys I'm just looking at I'm
- 45:17just looking at the markets today git
- 45:19Labs down 15 snowflakes down 13
- 45:23Mondays down 14 percent uh at least down
- 45:2730 percent in one day a Yelp is down 17
- 45:30percent
- 45:31is down 16 percent
- 45:34so it's just a horrible oh my gosh the
- 45:36cloud computing index wcld has hit a new
- 45:40low for the year it's down to 23 bucks I
- 45:43think the previous low was 25 is down
- 45:45almost eight percent today and this is
- 45:47on a day in which the NASDAQ is down
- 45:48less than one percent so the point is
- 45:51they're rotating out of growth stocks
- 45:53yeah it's just brutal and so listen if
- 45:56you're a startup founder you got to
- 45:57realize these are like some of the
- 45:58highest quality public so Leo's down 40
- 46:01today twilio is down 37 in a day today
- 46:05whoa but guys this is this is just math
- 46:09you know it's not a judgment on any of
- 46:12these companies it's just pure math this
- 46:14is why I think you have to be utterly
- 46:15unemotional in this moment and if you're
- 46:18if you're a CEO running a company
- 46:20particularly a SAS business
- 46:23you have to really figure out how to
- 46:26how to right size your cost basis and
- 46:28make this money last profitable
- 46:30industrial companies are Bill Gurley had
- 46:32a tweet a tweet about this a few months
- 46:34ago about how the biggest mistake people
- 46:36make in riffs is they just do like a
- 46:38tepid riff like a 10 ish riff and they
- 46:41have to come back and they do it again
- 46:42and they do it again this is what I
- 46:44think the the Elon action this week
- 46:46really sets a standard he shows the
- 46:48entirety of Silicon Valley that you can
- 46:50cut deep and you can turn a profit and
- 46:52you can do it fast and it could set a
- 46:54new standard for how folks are managing
- 46:56this Jack Welch used to in his
- 46:58management principles recommend dropping
- 47:00the bottom 10 of people every year and
- 47:02so you know the 10 13 Cuts don't really
- 47:05pass muster as a public market investor
- 47:07kind of looks at the the management
- 47:09across these different companies to turn
- 47:11a profit they're going to say the folks
- 47:13that are making the deepest cuts the
- 47:14fastest are the ones that are going to
- 47:15get valued it's unfortunate and it's a
- 47:17difficult circumstance for everyone in
- 47:19Silicon Valley to deal with from the
- 47:21employees to the investors to the public
- 47:23and private shareholders it's really
- 47:25brutal one quick question for you guys
- 47:26really it's really just this kind of
- 47:28Market motivation that's underway right
- 47:29now here's the chart uh and my question
- 47:31for you is when do Google and Facebook
- 47:34stop this I mean if you look at the
- 47:36number of employees being added it is
- 47:39truly extraordinary here's the chart and
- 47:40this includes the latest quarter so they
- 47:43are
- 47:45not turning off hiring yet what do you
- 47:49think hold on didn't they announce a
- 47:51hiring freeze
- 47:52they announced that they were at Google
- 47:54they announced that they were going to
- 47:56hold people accountable to better
- 47:57performance and they were going to go do
- 47:59more with less and then they added more
- 48:00people Facebook said that they would do
- 48:03a hiring three percent today yeah
- 48:04Facebook said it would do a hiring
- 48:06freeze
- 48:07well whatever jobs last quarter yeah
- 48:11well you're right they just announced
- 48:12the hiring freeze you look at Apple
- 48:14Apple just announced in non-r D
- 48:16functions a hiring freeze this is Apple
- 48:18like the most valuable most profitable
- 48:21company in the world so if Apple
- 48:23basically is putting the brakes on
- 48:25non-engineering hiring that tells you
- 48:27something about how fast the economy is
- 48:29slowing down I think that was a huge
- 48:31signal yeah the point Freebird makes is
- 48:33so correct which is if you're doing a
- 48:36riff obviously there's a reason why but
- 48:38I think we we're seeing too many riffs
- 48:40where the details of the Riff and the
- 48:43magnitude of the Riff don't match up
- 48:44with what the objective of the Riff is
- 48:46the objective of the Riff for a lot of
- 48:48these companies should be to get them
- 48:51cash flow positive or at least to put
- 48:54them on a Runway or a trajectory where
- 48:57they can get cash flow positive with
- 48:58their existing cash on the balance sheet
- 49:00right they won't need to raise money
- 49:01again and we're seeing a lot of
- 49:04companies where they don't achieve that
- 49:05and they have to come back again and
- 49:07again and hit it again and that creates
- 49:10more turmoil for the company and it's
- 49:12more unfair for the employees by the way
- 49:15sex to that point I'll just say
- 49:17how deep these come these companies are
- 49:18cutting and how you management is
- 49:20expressing shareholders how they're
- 49:22going to turn a profit becomes a signal
- 49:25for those shareholders on whether or not
- 49:26they want to stay in that stock and the
- 49:28companies that are doing it fast and are
- 49:30doing it deep the investors and the
- 49:32shareholders say you do actually have a
- 49:33path that makes sense here I'm going to
- 49:35stay in the stock cash today versus cash
- 49:36in the future sure off let me ask you a
- 49:38question in terms of strategy for one of
- 49:40these companies let's say the Facebook
- 49:42Corporation or
- 49:44perhaps even Google
- 49:46or apple even if they were to cut their
- 49:49expenses which might take obviously a
- 49:51riff and then because their stock prices
- 49:54are so depressed right now maybe even a
- 49:55mid cap one like a twilio or an Uber or
- 49:58an Airbnb if they were cut costs and
- 50:01then start buying back their shares
- 50:02which some companies have been doing
- 50:04what would that do in terms of the
- 50:06Market's appreciation of those stocks or
- 50:07management teams I think it's hard to
- 50:09tell I think that
- 50:11the if you have not lost investor trust
- 50:15I think it would be really well rewarded
- 50:18if you have become unreliable
- 50:22and undisciplined
- 50:25even those cuts I think would be met
- 50:27with some amount of excitement but
- 50:31but probably not a broad base support so
- 50:33you know it then it just goes to
- 50:35narrative meaning if Google did it I
- 50:38think that people really trust Sundar
- 50:40and Ruth
- 50:42and I think the stock would go Bonkers
- 50:44they would they would probably move very
- 50:46quickly into the echelon of apple and
- 50:49apple is sort of
- 50:51a first among equals like they're just
- 50:53they're just in a different class unto
- 50:55themselves
- 50:56Facebook I think is a little bit harder
- 50:58because I think folks have gotten burned
- 51:00and you know they would have to make
- 51:02some really really deep Cuts but then
- 51:04you know where do you do it you can't
- 51:06capitulate on this meta strategy
- 51:08but then the other part is where you
- 51:09make all the money
- 51:11and so you have this huge morale issue
- 51:13that you have to manage so it's just a
- 51:15really hard game to play just one more
- 51:17thought on on
- 51:19um on the rift stuff I think one thought
- 51:22experiment for Founders is to think
- 51:24about what was your plan at the end of
- 51:262019 why do I say that because 2020 and
- 51:292021 were two of the most distorted
- 51:32years ever in the history of financial
- 51:33markets and the economy because we had
- 51:36covet and then we had the reaction to
- 51:38covid right and so you saw there was
- 51:40this um you know zooms market cap hit
- 51:42100 billion all the e-commerce companies
- 51:44were doing extremely well you you know
- 51:46you had all this money printing you know
- 51:48you had zero interest rates and so on
- 51:50you had SAS companies hitting all-time
- 51:52Highs at the end of 2021 so we lived
- 51:55through this incredibly distorted time
- 51:57so as a thought experiment go look at
- 51:59what your plan for 2020 was supposed to
- 52:02be when you created it at the end of
- 52:042019 because that was the last time that
- 52:06you were thinking without any
- 52:08distortions you know that were then
- 52:10created and I think if you were to go
- 52:12back and look at your 2020 plan again
- 52:15created it at the end of 2019 you'd
- 52:18probably see that you could get by with
- 52:20half the head count you have now because
- 52:22probably you doubled your head count
- 52:23during the last two years during these
- 52:25heady heady times and yet I think
- 52:27Founders start thinking oh I can't go
- 52:29back to operating you know I can't
- 52:31operate at half the level of head count
- 52:32but you were you were operating with
- 52:34half the level of head count by death
- 52:36definition at some earlier point I also
- 52:39think sometimes I think what Founders
- 52:40say is what will people think if I cut
- 52:4350 meaning all of a sudden the perceived
- 52:46success of my business would be
- 52:47different and I think that this is where
- 52:49you have to realized no like there's a
- 52:51lot of ego tied up in these things which
- 52:54slows people down from doing the thing
- 52:55that they need to do
- 52:57yes it's a really it's a really it's
- 52:59hard to do I mean look at Airbnb as an
- 53:02example I mean they did this ginormous
- 53:04riff
- 53:05during covid because they had no choice
- 53:07I mean they're they're Revenue went
- 53:09essentially to zero and now the business
- 53:11is incredibly strong it's throwing off
- 53:13massive amounts of free cash flow and
- 53:15the stock market seems to really love
- 53:16what Airbnb has done uh and a similar
- 53:19story over at Uber in terms of having
- 53:21done significant riffs and probably
- 53:22could
- 53:25is still down almost 75 off its high
- 53:29right so when you say the stock market
- 53:30love it so they're they're up today
- 53:32three percent so meaning they're not
- 53:34down 30 in one day but they have gone
- 53:37down with the rest of the market they
- 53:38have gone down with the rest of the
- 53:39market
- 53:40but it feels like the business I'm
- 53:42talking about the business fundamentals
- 53:43when you're throwing off almost a
- 53:44billion dollars yeah now you're going to
- 53:47start people are going to perceive that
- 53:48business maybe as uh of this cohort the
- 53:51flight to safety right or same thing
- 53:53with Uber throwing or free cash flow now
- 53:54I think a lot of these names are gonna I
- 53:56don't know Airbnb right now but they do
- 53:58on Uber I think the people throwing off
- 53:59the free cash flow are going to look
- 54:00pretty attractive
- 54:02and be able to buy their stock back
- 54:03maybe all right let's talk about the
- 54:06midterms
- 54:08a lot of big uh Senate races and
- 54:11obviously Governors uh Pennsylvania
- 54:13Georgia Arizona Wisconsin Ohio all
- 54:16really important races sex what do you
- 54:19think
- 54:20well it looks to me like there's going
- 54:22to be a republican wave there was an
- 54:24interesting article actually on CNN
- 54:25where they it's called five scary
- 54:27numbers for Democrats and what they
- 54:30point to is that Biden right now has a
- 54:3542 percent approval rating 61 percent of
- 54:38the American people say he hasn't
- 54:39focused on the key problems so this is
- 54:41called the out of touch index 51 say the
- 54:44economy is number one issue compared to
- 54:45only 15 for abortion and then 78 say
- 54:48we're on the wrong track I don't think
- 54:49I've seen a right track wrong track
- 54:51index that was so negative and 75
- 54:54percent of the country says we're in a
- 54:56recession so you know when you look at
- 54:58polling numbers like that it must
- 55:00translate I think into a republican wave
- 55:04and you have now Real Clear Politics
- 55:05currently has the GOP gaining four
- 55:08Senate seats so winning in the Arizona
- 55:10Nevada Georgia and New Hampshire that's
- 55:12a big change from just a couple weeks
- 55:14ago and winning 31 House Seats so
- 55:17this is this is kind of what it's
- 55:19looking like right now but look the the
- 55:21margin is still within the
- 55:23within the margin of error on the
- 55:25polling so Nate silver has pointed out
- 55:27that within one standard deviation you
- 55:30could either have a republican wave or
- 55:32you could have basically the Republicans
- 55:35fizzle out so it's going to be very
- 55:37close but ultimately I think this breaks
- 55:39Republican yeah the to me the way that
- 55:43I've I'm looking at it right now is that
- 55:45it seems like most scenarios the
- 55:48Republicans will have the majority in
- 55:50the house
- 55:51and the real question is what happens in
- 55:53the Senate it's really really kind of a
- 55:55coin flip
- 55:57and that's going to be really
- 55:58interesting to see so you know things
- 56:00where I thought would break Republican
- 56:02in the Senate like Pennsylvania are now
- 56:05back to almost a you know a statistical
- 56:07Dead Heat
- 56:08so it's a really interesting moment
- 56:10actually it's uh but most scenarios
- 56:13David I think you'd agree is that the
- 56:15Republicans win the house and then
- 56:17there's a non there's a plurality of
- 56:19scenarios where they also win the Senate
- 56:21the house will almost certainly go
- 56:22Republican but I think the Senate now
- 56:24the the official percentages are 55
- 56:26percent likely to tip Republican but I I
- 56:29just think that in a wave year like this
- 56:31where the wrong track sentiment is so
- 56:34high I think all these races that are a
- 56:36dead heat they're more likely to break
- 56:38in One Direction as opposed to like a
- 56:40random distribution which is why I think
- 56:42you could just as easily end up with and
- 56:45you know instead of it being a 5149
- 56:48Senate it could be 55 45 because all
- 56:52these things could break the same way so
- 56:53right now so I I would slightly disagree
- 56:55in Pennsylvania I think Oz has improved
- 56:58as a candidate fetterman did that debate
- 57:00and since he suffered that stroke he
- 57:02kind of came across as somebody how do
- 57:04we feel about that I I I had very very
- 57:07hard to watch that happen and yeah I
- 57:10mean the guy the guy has suffered a
- 57:11stroke and is sad but he you know he
- 57:13doesn't present as someone who can be a
- 57:15senator right now I think what does the
- 57:17science say about that like a re as a
- 57:20society is this a good idea to have
- 57:22somebody post-stroke be in office I'm
- 57:23not picking any political side here I'm
- 57:24just talking about the the medical issue
- 57:26Alice is actually doing the right thing
- 57:28right now which is he's not actually
- 57:29focusing on that issue because it's so
- 57:31obvious he doesn't want to be seen as
- 57:33beating up on fetterman and instead he's
- 57:35a human he's focusing on the issues and
- 57:38actually fetterman's issues are very
- 57:40unpopular in a state like Pennsylvania
- 57:42so I actually think for both reasons Oz
- 57:45is going to win that I think fetterman's
- 57:46manifestly unqualified but also I think
- 57:49his positions are fairly unpopular so I
- 57:52think Pennsylvania will will almost
- 57:53certainly tip so let me pull up the
- 57:55chart here just so people can see Ohio
- 57:56is going Republican and then Arizona I
- 57:59think is really the interesting one
- 58:00where Blake Masters is now tied after
- 58:03being behind Mark Kelly throughout this
- 58:05campaign he is now tied in New
- 58:09is popular your guy is really unpopular
- 58:12and now he's tied
- 58:16interpretation it's the Peter too he was
- 58:18he was doing really poorly I think
- 58:20because
- 58:21I think listen I think that I think that
- 58:23Arizona is probably gonna be the closest
- 58:25race in the country I think it's gonna
- 58:26be a nail biter but I think Blake's
- 58:28gonna pull that out
- 58:29sex what do you think are the biggest
- 58:31policy shifts that take place in this
- 58:34country Host this predicted Red Wave is
- 58:38there anything that changes so just you
- 58:40know talk to folks about what's on the
- 58:42docket from a legislative point of view
- 58:44going into the next congress with all
- 58:48these new candidates the reality is we
- 58:49have a separation of powers in this
- 58:51country and you're gonna have to divide
- 58:53a government the Republicans will will
- 58:54control Congress the Democrats will
- 58:56control the presidency and so as a
- 58:58result you're going to be largely in a
- 59:00gridlock situation but gridlock may be a
- 59:03lot better than what we've had over the
- 59:04last couple of years so you know you've
- 59:06had basically this orgy of spending and
- 59:09money Printing and I think that's going
- 59:10to stop obviously
- 59:12the other thing that's going to happen
- 59:13is Republicans may not be able to pass
- 59:15much legislation but they're going to do
- 59:16investigations and there's a lot of
- 59:18questions that need to be answered I
- 59:19think about still about covid you know
- 59:22these lockdown policies that we had that
- 59:24started at the top at NIH why did they
- 59:26happen we need to start having
- 59:27accountability for some of these
- 59:29horrible decisions that were made during
- 59:30covid and there's been no willingness in
- 59:33Washington to hold anyone accountable at
- 59:34a minimum they need to have some
- 59:36Congressional investigations and find
- 59:38out why we pursued such bad policies
- 59:40over the last couple of years by the way
- 59:42did you see did you see what happened
- 59:43this week where the CDC
- 59:46you know after this entire opioid
- 59:48epidemic and all of these lawsuits the
- 59:50CDC came out and actually said Hey
- 59:52listen we need to really make sure that
- 59:54we're getting access
- 59:57putting opioids in the hands of
- 59:58Americans who are really suffering with
- 1:00:00pain management and whatnot and I didn't
- 1:00:03read the article to really understand
- 1:00:04the details but I just thought it was an
- 1:00:06incredible headline where it's like it's
- 1:00:08just it's so counter to The Narrative of
- 1:00:10what we've been told is happening which
- 1:00:11is like you know over prescription and
- 1:00:13misprescription if we learned anything
- 1:00:15during Covetous to question every
- 1:00:17organization everybody and to really
- 1:00:19collect your own information while you
- 1:00:22know looking at these organizations we
- 1:00:25trusted over time I know I look at the
- 1:00:26world differently now that you couldn't
- 1:00:28say covid was possibly a lab leak
- 1:00:31without having your podcast taken down
- 1:00:32or being banned on YouTube and now
- 1:00:35propublica has done an investigation and
- 1:00:38they're saying along with Vanity Fair
- 1:00:39and they're going to win a Pulitzer for
- 1:00:40this I bet
- 1:00:41that this conspiracy theory from two
- 1:00:43years ago is probably actually the
- 1:00:45leading theory and that the the Wuhan
- 1:00:49lab Lab was showing if you didn't see it
- 1:00:52reporting an incident in late November
- 1:00:54of last year uh before covet broke 2019.
- 1:00:58it's really it's really incredible there
- 1:00:59was an article in the Atlantic
- 1:01:01that came out over the past week called
- 1:01:03let's declare a pandemic amnesty no yeah
- 1:01:07investigation right so basically at
- 1:01:10everything yes all the experts who told
- 1:01:13us Jason that we weren't allowed to have
- 1:01:14an opinion because we weren't expert
- 1:01:16enough that if we raise any questions
- 1:01:18about the origin of the virus that it
- 1:01:20might have come from a lab that that
- 1:01:21basically needs to be censored the
- 1:01:23people who said we had to do lockdowns
- 1:01:24and implemented all these authoritarian
- 1:01:26tactics now they're saying that they
- 1:01:29need an amnesty that what that really
- 1:01:30means no one's looking no one's looking
- 1:01:32to criminally prosecute them what we're
- 1:01:34looking to do is have some
- 1:01:35accountability around the public policy
- 1:01:37what they want is they want to pull the
- 1:01:39expert card to say that they're the only
- 1:01:41ones who get to have an opinion and make
- 1:01:42a decision but then when it all goes
- 1:01:44horribly awry they basically want to be
- 1:01:46completely insulated and unaccountable
- 1:01:48no account in their decisions no way no
- 1:01:50way we're not going to give you full
- 1:01:52investigations we're in alignment on
- 1:01:54this side by the way can I just yes hold
- 1:01:55on I just want to say sex we're in
- 1:01:57alignment on this for a rare moment of
- 1:01:59Peace on this podcast the same thing
- 1:02:01after 9 11 shouldn't all Americans
- 1:02:03understand what happened after 9 11 and
- 1:02:05what the failures were in our
- 1:02:07intelligence just so we can get better I
- 1:02:09I'm not picking a political horse here
- 1:02:10but it's kind of crazy that you could
- 1:02:13people said to our podcast and other
- 1:02:15people who were questioning it forget
- 1:02:17about what political party you're in
- 1:02:19just want to understand how the world
- 1:02:20Works what are the chances that this
- 1:02:23breaks out in the one or two places
- 1:02:24where they're studying the coronavirus
- 1:02:26that you have a lab leak it was so
- 1:02:28obvious to everybody the other reason
- 1:02:30why you need to have accountability for
- 1:02:31this is that there are still a long tail
- 1:02:33especially around the damage that we did
- 1:02:36to our kids educationally yes and now
- 1:02:38and now the over prescription of
- 1:02:40stimulants and so if you don't
- 1:02:41depression sensors you can't go after
- 1:02:43these problems like there was a there
- 1:02:46was like
- 1:02:48stimulant prescription is now the single
- 1:02:51biggest epidemic in children it is now
- 1:02:53twice as prescribed as contraceptives
- 1:02:56and Asthma drugs and why chamoth why are
- 1:02:59we doing this to get them to score
- 1:03:01higher on a test to be more attentive in
- 1:03:02school well it's it's actually this
- 1:03:04negative feedback loop where these
- 1:03:06children were miseducated during covet
- 1:03:12it had huge psychological and
- 1:03:15academic damage to them
- 1:03:18our test scores have fallen off of a
- 1:03:20cliff relative to how we used to do
- 1:03:21relative to other countries
- 1:03:24I think the teachers unions have found a
- 1:03:26way to try to explain it
- 1:03:29to basically Shield themselves from any
- 1:03:31sort of critique
- 1:03:33and so the loot and then part of that
- 1:03:35Loop is then to look at a bunch of kids
- 1:03:37that are underperforming in school and
- 1:03:39instead of saying well maybe these
- 1:03:41lockdowns and masking and all of these
- 1:03:43things that we implemented actually had
- 1:03:46a huge impact they say uh you know
- 1:03:47you're misbehaving so let's put you on a
- 1:03:49stimulant yeah it's crazy we're in that
- 1:03:51Loop right now just so you guys know the
- 1:03:53data is outrageous twice as many
- 1:03:56prescriptions for stimulants as the sum
- 1:03:59of contraceptives and Asthma drugs for
- 1:04:02All American Kids yeah it's not that
- 1:04:04suddenly everybody's got ADHD so we
- 1:04:07failed them we failed our children and
- 1:04:10and we're going to use stimulants to
- 1:04:11have them ketchup weeks but we should be
- 1:04:12doing Summer Schools after school
- 1:04:14programs
- 1:04:16we failed them because of our response
- 1:04:18to covet that is why we need answers to
- 1:04:20all that stuff because you need to link
- 1:04:21these things together to have some real
- 1:04:23accountability absolutely here is the uh
- 1:04:26just so we have the people see the
- 1:04:27numbers here's the 538 poll of uh how
- 1:04:30Joe Biden's popularity has switched this
- 1:04:32is uh 654 days into
- 1:04:35his presidency started out really strong
- 1:04:3754 and now a little rebound since the
- 1:04:41summer obviously that uh dip started uh
- 1:04:45with the economy it's the economy stupid
- 1:04:46and if we go down a little bit on the
- 1:04:49same page and you zoom in on the left
- 1:04:50there you can see compared to Donald
- 1:04:51Trump
- 1:04:52uh he started out much more popular than
- 1:04:54Donald Trump day by day and now he's
- 1:04:56just as unpopular as Donald Trump was at
- 1:04:58this point in his presidency well look I
- 1:05:00mean look the setup is really
- 1:05:01interesting for 2024 because it's
- 1:05:03probably going to be the case that we're
- 1:05:04in the middle of a recession going into
- 1:05:06that election cycle maybe we'll be sort
- 1:05:09of like getting ourselves out of it but
- 1:05:11there'll be a lot of economic damage
- 1:05:12high unemployment
- 1:05:14and you know typically
- 1:05:16folks in power will have to sort of be
- 1:05:18held accountable for that it's a really
- 1:05:20interesting setup that both Gavin Newsom
- 1:05:22and Ron DeSantis have to figure out now
- 1:05:25and navigate if they're going to get the
- 1:05:27nomination on each side and breaking
- 1:05:29news today sax would love to get your
- 1:05:31thoughts on this axio says uh and we'll
- 1:05:34go to science Corner next that Trump's
- 1:05:36going to announce on November 14th that
- 1:05:39he is running for president look I I
- 1:05:41kind of have the Joe Rogan philosophy on
- 1:05:43this which is why I give it oxygen let's
- 1:05:45just wait and see there's certainly no
- 1:05:46needs to talk about it before it happens
- 1:05:48you know we're not even past this
- 1:05:50election yet but but hey I want to go
- 1:05:52back to the the Biden popularity because
- 1:05:54I think part of the issue here is what
- 1:05:57are the arguments that Biden is making
- 1:05:59to the country about why people should
- 1:06:01vote Democratic and he gave another
- 1:06:04speech on Wednesday night where he
- 1:06:07basically claimed that if you vote for a
- 1:06:10different party that that is a threat to
- 1:06:12democracy in other words the
- 1:06:13perpetuation of single party rule is
- 1:06:16what you must do if you care about
- 1:06:17democracy that is a sales pitch that's
- 1:06:20not going to appeal to anybody outside
- 1:06:21of the viewers of MSNBC it's just not
- 1:06:24he's not talking about the issues that
- 1:06:25really matter to the country you know
- 1:06:27what the country wants to know is that
- 1:06:29he's focused on the economy he's focused
- 1:06:31on inflation he's focused on crime he's
- 1:06:33focused on the schools and fixing this
- 1:06:36learning loss that Jamal was just
- 1:06:37talking about he's not doing those
- 1:06:39things instead he's basically saying
- 1:06:41that the Democrats should be kept in
- 1:06:42power forever because there was a riot
- 1:06:45at the Capitol on January 6 and look
- 1:06:46that was a stain on the country okay it
- 1:06:49was terrible that that happened
- 1:06:50disgusting that is not a reason hold on
- 1:06:52a second that is not a reason to keep
- 1:06:53Democrats in power forever and actually
- 1:06:56there's a
- 1:06:57um a liberal guy a liberal Democrat
- 1:06:59named Josh Barrow who wrote a pretty
- 1:07:00good blog about this and what he said is
- 1:07:03the message is that there's only one
- 1:07:05party contesting this election that is
- 1:07:08committed to democracy the Democrats and
- 1:07:10therefore only one real Choice available
- 1:07:11if voters reject Democrats agenda or
- 1:07:14their record on issues including
- 1:07:16inflation crime and immigration they
- 1:07:17have no recourse to The Ballot Box they
- 1:07:19simply must vote for Democrats anyway
- 1:07:21and that argument is just not flying and
- 1:07:23actually he's a a Democrat who is
- 1:07:26pointing this out but I don't think that
- 1:07:28Democrats are getting the message on
- 1:07:30this but I think they will after this
- 1:07:32election and they're gonna have to find
- 1:07:34a new sales pitch to The Country well
- 1:07:35you know and he does have a good sales
- 1:07:37pitch doesn't each a month with these
- 1:07:39major bipartisan uh wins he had the
- 1:07:41infrastructure deal got done the
- 1:07:43technology bill and the chips you got
- 1:07:45gas prices going down yeah GDP growth
- 1:07:47you got job growth the problem is that
- 1:07:50those things happened frankly too early
- 1:07:52in his presidency and things are getting
- 1:07:54materially worse so I just sent you a
- 1:07:55link can you just throw this up here for
- 1:07:57a second you know Jason you mentioned
- 1:07:59this cheaper gas thing yeah but the
- 1:08:01reality is um if you look at this we
- 1:08:04have now depleted our strategic goal
- 1:08:06Reserve by almost 50 percent yep so we
- 1:08:09are running out of
- 1:08:10oil that we can introduce into the
- 1:08:12market at effectively zero cost to bring
- 1:08:15the price down and because we've lost
- 1:08:17our relationships with folks like Saudi
- 1:08:19Arabia there's no way to influence them
- 1:08:22in order to produce more in fact they're
- 1:08:24going to cut Supply so that they can
- 1:08:26control the prices that they have which
- 1:08:29that they can sell into the market and
- 1:08:32so now what are we left with well the
- 1:08:34only three places where you can have
- 1:08:35incremental supply of energy which the
- 1:08:38country still needs is from Russia Iran
- 1:08:41and Venezuela
- 1:08:43and so you know all of these things
- 1:08:45Jason I think come back
- 1:08:47and really put Biden in a tough place
- 1:08:48because as as Sac says he does have to
- 1:08:51answer to all of these things because
- 1:08:52these are his decisions
- 1:08:54look I still believe in the Democrats
- 1:08:56you know I I'm hoping I gave a million
- 1:08:59bucks uh to the Senate pact trying to
- 1:09:01sort of tip the Senate I really think
- 1:09:03it's important that we have a split
- 1:09:05government because I've kind of I gave
- 1:09:06up on the house I think it's clear that
- 1:09:08the Republicans are going to win but the
- 1:09:10Senate is still is still up for grabs
- 1:09:12and the reason is because I think that
- 1:09:14we need to sort of have stasis so that
- 1:09:17nothing bad happens between now and 2024
- 1:09:20because I think the economic conditions
- 1:09:22on the ground are going to be bad in and
- 1:09:24of themselves
- 1:09:27and then just the one last thing I'll
- 1:09:29say is
- 1:09:30the instructive thing that I think we
- 1:09:32should look at is what happened in
- 1:09:33Germany
- 1:09:34because what happened in Germany is
- 1:09:36really interesting when the economy
- 1:09:37turns and inflation is out of control
- 1:09:39and energy is out of control
- 1:09:42what they basically did was they
- 1:09:43sidelined
- 1:09:45the European Central Bank they stepped
- 1:09:48in with their own balance sheet and said
- 1:09:49you know what we're going to nationalize
- 1:09:51assets and I know that this sounds crazy
- 1:09:53to say but if it can happen in a place
- 1:09:55like Germany I know most people would
- 1:09:57say it'll never happen in America but
- 1:09:59I'm not so sure and I think that you
- 1:10:02want to make sure that there's a split
- 1:10:04government so that these things are
- 1:10:06never possible and so hopefully there's
- 1:10:09some you know Common Ground in a
- 1:10:11Democratic Senate and a republican house
- 1:10:13and we just kind of get through 24 and
- 1:10:15see where the chips land and I still
- 1:10:17think it's going to be uh DeSantis
- 1:10:19versus uh Newsome Freeburg any final
- 1:10:21thoughts here on politics my first um
- 1:10:24observation is that I think it's funny
- 1:10:25that chamoth and sax are funding
- 1:10:27opposite uh sides of the uh
- 1:10:30yeah why don't you just guys just give
- 1:10:32the money to me and Friedberg to get a
- 1:10:34plan each other's money up yeah I could
- 1:10:37think of other ways for you guys to use
- 1:10:38that money but David and I may have
- 1:10:39canceled each other out you're right I
- 1:10:41mean yeah so far Peter Thiel made the
- 1:10:43better trade he's it looks like the teal
- 1:10:44wave in the Senate so look I would say
- 1:10:46my very broad statement is
- 1:10:49democracies evolve in a cyclical nature
- 1:10:52over time right you often see swings
- 1:10:55from one political party to the other
- 1:10:58and um it's just the nature that once
- 1:11:00someone's been in office they form the
- 1:11:02new establishment and then folks in the
- 1:11:05next election cycle want to vote against
- 1:11:06that establishment because there are
- 1:11:08things that they want that they aren't
- 1:11:09being given today and therefore the
- 1:11:11Democracy forces a change from what is
- 1:11:14the current establishment back to the
- 1:11:16other side and generally political
- 1:11:17parties seem to kind of adopt whatever
- 1:11:19the other side is and that's how the
- 1:11:21cyclical evolution of democracy seems to
- 1:11:23play out the recent Trend that has been
- 1:11:25more alarming which I think we can kind
- 1:11:27of take pause to notice is the rise of
- 1:11:30populism where populism is this really
- 1:11:32kind of vehement Die Hard opposition to
- 1:11:35elitism and the establishments that
- 1:11:37everyone feels kept down by and everyone
- 1:11:39feels taken advantage of by
- 1:11:41and um the the rise of trump the rise of
- 1:11:44bolsonaro the rise of Boris Johnson and
- 1:11:47I would argue even the rise of AOC
- 1:11:49Bernie Sanders and Elizabeth Warren all
- 1:11:52similarly speak to the the crying voice
- 1:11:56of the the Democratic
- 1:11:59populations that they want to see these
- 1:12:03establishments taken apart they don't
- 1:12:06feel like they're Fair they don't feel
- 1:12:07like they're just they don't feel like
- 1:12:09the institutions that oversee us and are
- 1:12:11meant to service us are servicing us
- 1:12:14um and so there was this big rise the
- 1:12:16problem is like a normal pendulum would
- 1:12:18swing back and forth between one side
- 1:12:19and the other with the rise of populism
- 1:12:21you get such a strong push of that
- 1:12:23pendulum it can knock through a wall and
- 1:12:25I think we saw that on January 6th and I
- 1:12:27think it gave a lot of people pause we
- 1:12:29saw the the motion of brexit knocking
- 1:12:33through a wall and we saw these kind of
- 1:12:35very radical outcomes and then the cost
- 1:12:38of those outcomes
- 1:12:40blow up in our face and as a result I
- 1:12:43think we're seeing a bit of a receding
- 1:12:45of the tides right now away from
- 1:12:46populism during this current electoral
- 1:12:49cycle where folks are saying you know
- 1:12:51what maybe we just need to have some
- 1:12:52sort of an establishment so I can feel
- 1:12:54safe and secure less than the volatile
- 1:12:56volatility that I've experienced of late
- 1:12:58look I think you look at the economic
- 1:13:00mess we're in okay populist did not
- 1:13:02cause that okay populists did not cause
- 1:13:0410 trillion dollars of money printing it
- 1:13:06was Modern monetary Theory and the
- 1:13:08experts the FED who did that it wasn't
- 1:13:10populous who created the great financial
- 1:13:12crisis of 2008 that caused the zurp and
- 1:13:14we're still living with all the
- 1:13:16downstream effects of that it was the
- 1:13:18experts on Wall Street who said they
- 1:13:20could manage all these derivatives and
- 1:13:22the collateralized mortgage obligations
- 1:13:24and all that stuff that they lost
- 1:13:26control over I would argue hold on
- 1:13:32it was not populous who caused the
- 1:13:36horrible handling of that pandemic even
- 1:13:38though they were blamed for remember we
- 1:13:39were told it was a pandemic of the
- 1:13:41unvaccinated then it turns out the
- 1:13:42vaccine doesn't stop it it was not
- 1:13:45populous who caused the reaction to the
- 1:13:46pandemic it was the experts the CDC and
- 1:13:49falching people like that who shut down
- 1:13:51our economy who caused the learning loss
- 1:13:54it was those experts so Freeburg listen
- 1:13:56you may not like this populist waiver
- 1:13:58that we have in the country and I get
- 1:13:59that but it's in reaction to something
- 1:14:01real which is the failure of this expert
- 1:14:04class and if you want to stop having
- 1:14:07this populist wave rise up we need to
- 1:14:10start having experts in position of
- 1:14:12power who actually know what they're
- 1:14:13doing well one way to say that sorry
- 1:14:15Jake out hang on a second I don't have
- 1:14:16any opposition to the populist wave I'm
- 1:14:19making the observation that the uh the
- 1:14:21effects of some of the populist
- 1:14:23movements have started to become too
- 1:14:25volatile for people to feel like they
- 1:14:27should continue forward with that
- 1:14:28electoral path that was my observation
- 1:14:30okay I'm not kind of criticizing the
- 1:14:32populist movement I'm just saying that
- 1:14:34events like January 6th and the
- 1:14:36conditions in the UK for example are
- 1:14:38making people say wait a second maybe I
- 1:14:40need to take pause on the extreme the
- 1:14:42bond market basically fired list trust I
- 1:14:44mean she's not a populist and you know
- 1:14:46in Bolson bolsonaro in Brazil he
- 1:14:49actually just lost and there was this
- 1:14:51big narrative that somehow he was gonna
- 1:14:53not relinquish power and he just
- 1:14:55announced that he will relinquish power
- 1:14:56right so you know some of the stuff that
- 1:14:59is about how populists pose this great
- 1:15:01danger I think is threat inflation and
- 1:15:04that the threat is magnified by Elites
- 1:15:06who want to stay in power and the truth
- 1:15:08of the matter is we need accountability
- 1:15:10for the people in power and when they
- 1:15:12set the wrong policies and decisions
- 1:15:13they need to be replaced no more no more
- 1:15:16unaccountability yeah I
- 1:15:19just just to my personal belief 100
- 1:15:21agree
- 1:15:23that's all of these institutions
- 1:15:26accountability maybe competence and also
- 1:15:28transparency and accountability like I
- 1:15:30think that's what the public wants I
- 1:15:31mean competencies
- 1:15:35there's no way to perfectly react to the
- 1:15:38pandemic but in your mistakes owning
- 1:15:41them and explaining them would it be
- 1:15:43much better than trying to obscurify it
- 1:15:45and asking for amnesty chamoth you're
- 1:15:47not um if you want to hear an incredibly
- 1:15:49interesting interview
- 1:15:52because it's very thought-provoking of a
- 1:15:55modern Progressive uh but with a very
- 1:15:57different mindset or sorry you know
- 1:16:00maybe you don't want to call him a
- 1:16:01progressive but is the president of El
- 1:16:04Salvador naive bouquelli and he did this
- 1:16:06incredible interview with Tucker Carlson
- 1:16:08on Fox News I encourage everybody to
- 1:16:10watch it on both sides of the political
- 1:16:12Spectrum
- 1:16:13that man is impressive
- 1:16:15did we just get an admission that your
- 1:16:17mouth watches Tucker I watch I watched
- 1:16:19that interview you watch the talker oh
- 1:16:21my Lord Jason's head's explode you know
- 1:16:23because I I try not to be against the
- 1:16:25moment ignoramus it's an Entertainer I
- 1:16:27like to watch things on both sides but
- 1:16:29that interview is incredible He is
- 1:16:31unbelievable impressive and it's a it
- 1:16:33double clicks into you know the
- 1:16:35skepticism that smart people like him
- 1:16:38the outsider class has with The Insider
- 1:16:41expert class in a nutshell if you want
- 1:16:43to see it I would encourage you to watch
- 1:16:45this interview because it's it's
- 1:16:46incredible incredible really really
- 1:16:48Jason The Peasants with pitchforks are
- 1:16:51rising up against this Elite Class who
- 1:16:54put themselves up they've set themselves
- 1:16:55up as Lords they want exclusive control
- 1:16:58over their blue checks and we're about
- 1:17:01to overturn this establishment because
- 1:17:04it is corrupt and it is incompetent
- 1:17:08be great if the people who worked for us
- 1:17:09were confident back on Megan Kelly owned
- 1:17:12and we're transparent you know I think
- 1:17:14that's why people are opting out of this
- 1:17:16is they don't feel
- 1:17:18that there's a level of competence in
- 1:17:20these institutions nor ownership and
- 1:17:22transparency and it really is
- 1:17:24frustrating whether it's education or
- 1:17:26it's health or
- 1:17:28you know any of these topics we've
- 1:17:31talked about here on the show let's go
- 1:17:32to science corner and we can rap
- 1:17:34what do you got free bark for us to mock
- 1:17:36I think we were going to cover the
- 1:17:39Facebook meta announcement that their AI
- 1:17:42research team had generated the physical
- 1:17:45structure of 617 million proteins
- 1:17:49from these metagenomic data sets and so
- 1:17:52remember Alpha fold made this big
- 1:17:53announcement that they had highly
- 1:17:56um accurate predictions of protein
- 1:17:58structure the three-dimensional shape of
- 1:17:59proteins and remember proteins are kind
- 1:18:01of the Machines of biology that do
- 1:18:03everything from catalysis to enzymes
- 1:18:05where they break stuff down and they're
- 1:18:07like you know they have all this
- 1:18:09structure that allows them to do
- 1:18:10specific physical things and proteins
- 1:18:12are coded in DNA every three letters of
- 1:18:14DNA codes for an amino acid a string of
- 1:18:16amino acids makes a protein
- 1:18:19and so you know we have about a million
- 1:18:21species
- 1:18:23where we've sequenced the entire Genome
- 1:18:25of those species only about 3 000
- 1:18:27Animals by the way including humans
- 1:18:29half a million from bacterial species
- 1:18:31and then a bunch of viruses and other
- 1:18:34stuff but but call it about a million
- 1:18:35species that we've sequenced and so
- 1:18:38you know earlier this year
- 1:18:40Google's Alpha fold project published
- 1:18:42the 3D structure of 200 million proteins
- 1:18:45that they had derived from the whole
- 1:18:47genome databases that existed where
- 1:18:49we've gone through and figured out
- 1:18:50what's the full DNA sequence of all
- 1:18:52these different species
- 1:18:53now
- 1:18:55when you look at the DNA in the
- 1:18:56environment around us you were just to
- 1:18:59take the DNA out it turns out that we
- 1:19:01have seen very little of that DNA the
- 1:19:04vast majority of DNA that you would find
- 1:19:07in a teaspoon of soil for example we've
- 1:19:10never classified it's not part of a
- 1:19:12species that we've actually built the
- 1:19:13whole genome around we may not even know
- 1:19:15what species that DNA is from and so
- 1:19:18when you take a teaspoon of soil you'll
- 1:19:20get about 100 billion microorganisms in
- 1:19:22that soil from about a million unique
- 1:19:24species but you don't see those species
- 1:19:26because the way DNA sequencing or
- 1:19:28shotgun sequencing works is DNA is
- 1:19:30chopped up into little 250 base pair of
- 1:19:33Lights little 250 strands and those 250
- 1:19:36letters are read at a time and then
- 1:19:38statistically bioinformatics puts
- 1:19:41together all of that little DNA segments
- 1:19:43and tries to create long strands of DNA
- 1:19:45to figure out what the genes are or what
- 1:19:47the whole genome is and so shotgun
- 1:19:49sequencing gives us kind of a snapshot
- 1:19:51of the DNA but until we've done the hard
- 1:19:54work of figuring out the whole whole
- 1:19:55genome we don't know what species that
- 1:19:57DNA comes from so when you take a sample
- 1:20:00of soil or you take a sample of human
- 1:20:02poop and you sequence it or even a
- 1:20:04teaspoon of ocean water and you just
- 1:20:06sequence the DNA in it you get all of
- 1:20:09these little segments of DNA that we've
- 1:20:10never seen before and you can string
- 1:20:12them together statistically because you
- 1:20:13get lots and lots of copies of them and
- 1:20:15you can figure out the overlap and then
- 1:20:17you can create these genes and a gene is
- 1:20:19a segment of DNA that codes for a
- 1:20:20protein and those genes make up the
- 1:20:23metagenome or the combination of all the
- 1:20:25genes that we find in a in a piece of of
- 1:20:28the environment and that meta genome
- 1:20:31comes from millions of species that
- 1:20:32we've never seen before so what Alpha
- 1:20:35what they did at meta is they took all
- 1:20:36of those genes that we pull out of the
- 1:20:39soil or we'd pull out of the ocean and
- 1:20:40they picked a bunch of random samples
- 1:20:42and they then predicted the physical
- 1:20:44structure of the proteins from just
- 1:20:47those genes without knowing what
- 1:20:50organism they came from and this gives
- 1:20:52us a whole new universe of proteins that
- 1:20:54we've never classified before or never
- 1:20:57seen before now I will just kind of
- 1:20:59speak a little bit critically about it
- 1:21:01number one they didn't do what Alpha
- 1:21:03fall did what Alpha full did is they
- 1:21:04took 3D structures from typically x-ray
- 1:21:07crystallography then they took the the
- 1:21:09DNA code and they built machine learned
- 1:21:11models to figure out the 3D structure
- 1:21:13from the DNA code what these guys did at
- 1:21:16meta is they took the 3D structures and
- 1:21:19the code and they basically did a fill
- 1:21:21in the blank they found all the
- 1:21:23metagenome data out of these samples and
- 1:21:25a lot of it was missing and they filled
- 1:21:27in the missing blanks using kind of
- 1:21:29common protein structure that existed
- 1:21:32out there in the wild that we already
- 1:21:33knew from the alpha full data and so
- 1:21:35they kind of did a fill in the blank and
- 1:21:37as a result it allowed them to very
- 1:21:38quickly build these 3D models versus
- 1:21:40doing the hard and rigorous work that
- 1:21:42Alpha fold had to do so they claimed
- 1:21:43that it was 60 times faster but it's
- 1:21:45actually an entirely different technique
- 1:21:47and the second thing is that they
- 1:21:49represent that only about a third of it
- 1:21:50is high quality meaning only about a
- 1:21:52third of the proteins that they've
- 1:21:54created structure for are really useful
- 1:21:56or or that could be kind of Applied uh
- 1:21:58in terms of this is the real
- 1:21:59representation now why is this
- 1:22:01interesting and important proteins can
- 1:22:03form the basis of new medicines so you
- 1:22:06know we can find proteins in the soil a
- 1:22:08genomes in the soil and proteins in the
- 1:22:10soil that can kill certain fungal
- 1:22:12pathogens that can kill bacteria and
- 1:22:14those can be turned into fungicides they
- 1:22:16can be turned into antibiotics we can
- 1:22:18find proteins that bind to specific
- 1:22:20things we can find proteins that fix
- 1:22:22nitrogen from the atmosphere and those
- 1:22:24proteins can be turned into new types of
- 1:22:25fertilizer so you know searching through
- 1:22:28this universe of proteins that exists in
- 1:22:31the metagenome will allow us to find new
- 1:22:33molecules to do new and interesting
- 1:22:35things with in the applied engineering
- 1:22:38world
- 1:22:38and I will say like this is what would
- 1:22:40the output of these be is what
- 1:22:41everybody's going to be thinking
- 1:22:42antibiotics fertilizers I mean the idea
- 1:22:45of the metagenome is rather than start
- 1:22:47with the species and then take the genes
- 1:22:49out of it just go get the genes the
- 1:22:51genes are already there they're in this
- 1:22:52they're in the ocean they're in the soil
- 1:22:53and there's millions of genes hundreds
- 1:22:55of millions billions of genes that we've
- 1:22:57never seen before therefore there's
- 1:22:58billions of proteins now we could
- 1:23:00randomly create proteins but the number
- 1:23:02of proteins that could exist is more
- 1:23:04than the number of atoms in the universe
- 1:23:05because remember there's 20 amino acids
- 1:23:07so 20 to the 200th power or 20 to the
- 1:23:10300th power or 20 to the thousandth
- 1:23:12power meaning how many different
- 1:23:13combinations of amino acids can you make
- 1:23:15that's more than there are atoms in the
- 1:23:16universe so the best place to start is
- 1:23:19what evolution has already given us all
- 1:23:21the proteins that exist in the
- 1:23:22environment so let's go find those
- 1:23:24proteins in the environment and then
- 1:23:26let's figure out what do we think they
- 1:23:27can be used for can they be used in
- 1:23:28industrial applications in medicine can
- 1:23:31they be doing them in Material Science
- 1:23:33you're saying Material Science and so
- 1:23:35you know a lot of drug Discovery mines
- 1:23:38proteins it tries to find proteins and
- 1:23:40figure out what can these proteins be
- 1:23:42used for and now we have all these new
- 1:23:44data sets of proteins that are being
- 1:23:46generated from these metagenomes and so
- 1:23:48it's amazing I mean you know look at the
- 1:23:50world around you look everywhere up and
- 1:23:52down on the walls on the ground below
- 1:23:54you there are billions of species of
- 1:23:57organisms that we've never classified
- 1:23:58before that are making billions of
- 1:24:00unique proteins that we've never
- 1:24:01classified before and any one of them
- 1:24:03could unlock an amazing commercial
- 1:24:06opportunity
- 1:24:07for industry so and for medicine and for
- 1:24:09human health that's what's really
- 1:24:11exciting about this ability to kind of
- 1:24:13mine the metagenome silly question for
- 1:24:15you or maybe not silly uh we have gotten
- 1:24:19the precursors to DNA for meteorites if
- 1:24:22I understand correctly
- 1:24:24what do they call them nucleobases
- 1:24:26nucleic acids yeah yeah
- 1:24:30um thymine Etc like things that exist in
- 1:24:33DNA
- 1:24:34that are precursors we've never had DNA
- 1:24:37from space obviously but we could at
- 1:24:40some point start to find DNA out there
- 1:24:42in space and this could have an even
- 1:24:43crazier impact on what we built here
- 1:24:46is that the next card to turn over after
- 1:24:47we every human gene home what's here no
- 1:24:50I wouldn't say so I like I think look if
- 1:24:52there's DNA that's coming to us for
- 1:24:54meteorites call it a couple hundred
- 1:24:55genes you could pick up a piece of uh
- 1:24:58soil and find over a billion genes in
- 1:25:00that teaspoon of soil right so uh we
- 1:25:03have far more to mine here on Earth and
- 1:25:05the low cost of DNA sequencing and
- 1:25:06shotgun sequencing coupled with
- 1:25:08bioinformatics where we take all that so
- 1:25:10just to give you guys when you take a
- 1:25:12teaspoon of soil and you get the DNA out
- 1:25:14and you read the DNA out of it sequence
- 1:25:16the DNA that's potentially tens of
- 1:25:18gigabytes of data and then you could do
- 1:25:21that millions of times over and then you
- 1:25:22statistically can find genes and then
- 1:25:24statistically estimate what they
- 1:25:26physically look like what those proteins
- 1:25:28look like and then you can start to
- 1:25:29build models around which ones do we
- 1:25:31want to try and use for drug
- 1:25:32applications which ones do we want so
- 1:25:34there's so much work to do
- 1:25:36it just in terms of what we have here on
- 1:25:38Earth and the tools are getting so cheap
- 1:25:40and so available there are Labs that are
- 1:25:42all over the world starting to kind of
- 1:25:44spring up to do this work it's super
- 1:25:45exciting
- 1:25:46adults
- 1:25:48it's kind of it you know just to put two
- 1:25:50ideas together I've said before like the
- 1:25:52two big investable themes that I'm
- 1:25:55orienting my organization around is this
- 1:25:57one is that the marginal cost of energy
- 1:25:59goes to zero and the second is that the
- 1:26:01marginal cost of compute goes to zero
- 1:26:03and the second one is really about
- 1:26:04shifting compute to more parallelism on
- 1:26:07gpus and Asics and fpgas but that's why
- 1:26:10all of this stuff is possible the fact
- 1:26:12that you know meta can do this and
- 1:26:14Google can do alpha fold is largely
- 1:26:17because the cost of all of this stuff is
- 1:26:20you know trivial for these kinds of
- 1:26:21companies so it's really exciting it's
- 1:26:23going to move science
- 1:26:25in my opinion out of this in Vivo in
- 1:26:28vitro experimentation model into silica
- 1:26:31and so those who can actually build
- 1:26:33learning machines will solve some of the
- 1:26:35most important biological problems so I
- 1:26:37I'm a real believer in this stuff I
- 1:26:39think it's super exciting when do you
- 1:26:41think this stuff actually hits Friedberg
- 1:26:43our life that's always when people talk
- 1:26:46about these discoveries yeah a lot of
- 1:26:47people don't realize it but so many um
- 1:26:49molecules that that are used in
- 1:26:51agriculture like fungicides to to kill
- 1:26:53fungus in the fields those are derived
- 1:26:56from this sort of work a lot of
- 1:26:58antibiotics a lot of medicines are
- 1:27:00already derived from mining genomes
- 1:27:02finding new proteins and seeing what
- 1:27:04those proteins can do because these
- 1:27:06proteins didn't evolve in the
- 1:27:07environment randomly they evolved to do
- 1:27:09something and in many cases we can take
- 1:27:11that thing that they do and then harness
- 1:27:13it into a product and that's what's so
- 1:27:16exciting and this this affects
- 1:27:17everything Material Science
- 1:27:19you know agriculture human health
- 1:27:22it's uh it's a food it's really profound
- 1:27:25awesome all right everybody there you
- 1:27:27have it that's another all in podcast in
- 1:27:29the camera by the way so many so many of
- 1:27:32Freeburg stands were afraid Jay Cal that
- 1:27:33you and I were gonna make some joke and
- 1:27:35we didn't no we didn't and so for all
- 1:27:37these fans I just I hope you guys can
- 1:27:39exhale
- 1:27:40take a deep breath man have some you
- 1:27:42know eggless mail and uh enjoy your
- 1:27:45weekend
- 1:27:46uh enjoy your week bye bye everybody see
- 1:27:48you next time love you besties love you
- 1:27:49guys
- 1:27:51we'll let your winners ride
- 1:27:54Rain Man David's side
- 1:27:59we open source it to the fans and
- 1:28:01they've just gone crazy with it
- 1:28:05[Music]
- 1:28:08besties
- 1:28:10[Music]
- 1:28:30is
- 1:28:34[Music]
- 1:28:40[Music]
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