Discussing Auvelity: The New Dextroantidepressant — Transcript

Full transcript

1. 0:00hello and welcome to the second channel
2. 0:02for Tales from the trip I'm your host
3. 0:03the trip keeper and on today's video
4. 0:05we're going to be reading some
5. 0:07experience reports from people who have
6. 0:09been on AEL which is if you guys did not
7. 0:12know it is a newer anti-depressant
8. 0:14that's on the market that actually
9. 0:15involves
10. 0:17bupropion and DXM dextromethorphan uh
11. 0:21they mix it together I think it's 45
12. 0:23milligrams of DXM and 105 milligrams of
13. 0:27bupropion uh let me make sure I'm
14. 0:29pronouncing that right
15. 0:31bupropion bupropion bupropion okay uh
16. 0:35bupropion or Wellbutrin that's the
17. 0:37that's the brand name for it so they
18. 0:39made this uh they made this pill um and
19. 0:43it's I think it's kind of expensive so
20. 0:45yeah okay so it says extended it's
21. 0:47extended release tablets 45 milligram
22. 0:49105 milligrams uh so yeah there's 45
23. 0:52milligrams of dextromethorphan 105
24. 0:54milligram of buproprion
25. 0:57HCL um and uh it is
26. 1:01is let's see I'm trying to find U about
27. 1:06aity uh how AEL may help uh AEL can help
28. 1:11relieve depression symptoms fast it's
29. 1:13the first and only rapid acting oral
30. 1:15anti-depressant label to start working
31. 1:16for some people as early as one week AEL
32. 1:19was studied in a six-week trial compared
33. 1:21to a compared it to a placebo okay uh
34. 1:24people taking aeli saw greater symptom
35. 1:27Improvement at 6 weeks compared to those
36. 1:28taking placebo all right so um I'm just
37. 1:33going to read from the website their
38. 1:35their own website aity uh this is this
39. 1:38has been so interesting to me I can't
40. 1:40believe they actually have this on the
41. 1:41market with like a DXM and bupropion
42. 1:44like just thinking of those drugs mixing
43. 1:47together like in my head like if you
44. 1:48were to do like an actual recreational
45. 1:50dose like that sounds terrible but like
46. 1:53in a in a low dose like this like a like
47. 1:55a micro dose of [ __ ] DXM and
48. 1:59buproprion like I don't I don't know
49. 2:00what a normal dose for a buproprion is I
50. 2:02never been on it I've never taken it so
51. 2:04I don't know um but I know it's I I I
52. 2:08feel like there's some people take
53. 2:10really high dosages of it um so yeah
54. 2:13this is like a more more subtle version
55. 2:15of it but the way it connects with the
56. 2:17brain I got to I got to write a page up
57. 2:18here so it's going to uh tell us all
58. 2:20about it this person you know said it
59. 2:22and uh said it nicely um but I'm on the
60. 2:25website right now and we're going to
61. 2:26read this um yeah cuz uh it's just very
62. 2:29interesting to me very because I'm
63. 2:31getting into the schooling uh I can't
64. 2:33wait to start it uh it's going to be
65. 2:34really fun so yeah I need to like learn
66. 2:37about this kind of crap um so on average
67. 2:40people taking AEL had a rapid
68. 2:41Improvement in their depressive symptom
69. 2:43scores versus placebo as early as one
70. 2:45week um average depress depression
71. 2:48scores were reduced in a study lasting
72. 2:50up to 12 months where both researchers
73. 2:51and patients knew they were taking
74. 2:54AEL um in the study comparing aity to
75. 2:57Placebo people rated how depression
76. 2:59disrupted their work/ school social life
77. 3:02and family life and home responsibility
78. 3:04on a scale uh
79. 3:07so what' they say about it then all
80. 3:10right they improve scores at six weeks
81. 3:13versus placebo okay uh there's some side
82. 3:16effects aity AA a
83. 3:21aity um so what is AEL it is
84. 3:25prescription oral medicine used to treat
85. 3:27adults with major depressive disorder
86. 3:28MDD so yeah it's only for people with
87. 3:30major depressive disorders so if you're
88. 3:32just got like General depression or you
89. 3:34know what I I you're probably not going
90. 3:36to get this cuz this is just for major
91. 3:38depressive
92. 3:39disorder um it is not known if aity is
93. 3:42safe and effective for use in children
94. 3:44yeah no I don't know if I'd be given
95. 3:45this to children that's for sure um aity
96. 3:48is not approv for uses other than the
97. 3:50treatment of MDD the ingredients in aity
98. 3:52bupropion and dextromethorphan are the
99. 3:54same ingredients found in same other
100. 3:55medicines approved for other users um
101. 3:59let me see what the interaction Checker
102. 4:01is uh because I'd like to know what it
103. 4:05is um cuz I don't know if uh if it's
104. 4:11actually God I can't even spell right
105. 4:13now okay uh drug interaction sorry
106. 4:19guys interactions Checker I love looking
107. 4:22at this crap uh bupropion and dextr
108. 4:27methorphan let's see dextro
109. 4:31no not
110. 4:33dextran dextr
111. 4:36methorphan all right let's
112. 4:39see uh there's a moderate interaction so
113. 4:43if it's moderate you know you got to
114. 4:46watch out for it but I don't think it's
115. 4:48like as bad as like you know you got to
116. 4:51watch out for like a major interaction
117. 4:53with it so it's a moderate interaction
118. 4:55but yeah no it's I think it's so low of
119. 4:57a dose like 45 migs of DXM that's not a
120. 5:00lot you know for you know I don't know
121. 5:03that's that's just crazy to me that
122. 5:05there's they they created a
123. 5:07anti-depressant with DXM in it that's
124. 5:09just [ __ ] wild um but yeah uh let's
125. 5:13see where is the one that I wanted to
126. 5:16read um oh let me go back to the
127. 5:19website uh let's see here all right no
128. 5:24there's yeah okay so serotonin syndrome
129. 5:27can happen you know very uh a rare a
130. 5:30disorder but it's life-threatening uh so
131. 5:33yeah um you
132. 5:35know it's it's scary [ __ ] scary [ __ ] um
133. 5:41okay so the most common side effects of
134. 5:44of of lity include dizziness headache
135. 5:46diarrhea feeling sleepy dry mouth sexual
136. 5:48function problems and excessive sweating
137. 5:51uh yeah no DXM I feel like it does not
138. 5:54you know it it when I've taken in the
139. 5:57past I have found that I cannot
140. 6:00release you know cannot release for a
141. 6:02couple days after so I don't know it's
142. 6:04it's very hard like I've done it but
143. 6:06it's very hard so that's all I'm going
144. 6:08to say um but yeah no this is just like
145. 6:11a weird mix like it's just like
146. 6:13something I wouldn't think that would go
147. 6:14together but they made it like they put
148. 6:16it like [ __ ] you we're going to put this
149. 6:17[ __ ] together um but yeah uh this this
150. 6:22is the okay so I'm on the r/ aity med
151. 6:26subreddit and this person put on here uh
152. 6:29from 2 months ago the science of
153. 6:30dissociation on aity please read I've
154. 6:33recently become reinter interested in
155. 6:35this medicine after talks with three
156. 6:36separate psychiatrists and personal
157. 6:37interest in Pharmacology and
158. 6:39biochemistry I'm going to prepare myself
159. 6:41for either the hate comments or the
160. 6:42anecdotal evidence that points to
161. 6:43otherwise but let's lay it out flat AEL
162. 6:47does not cause dissociation uh if you
163. 6:49took a lot of it it probably would you
164. 6:51know if you took like more than the
165. 6:53recommended dose the reason comes down
166. 6:56to the pharmacology and physiological
167. 6:58mechanism which AEL bupropion bupropion
168. 7:01dextromethorphan aapon dissociation AKA
169. 7:05to some robotripping can be attributed
170. 7:07to two main factors dosage and
171. 7:09biological mechanism oh boy depending on
172. 7:12the source noticeable effects can be
173. 7:14seen at dosages starting at 150 to 200
174. 7:16Mig of DXM even so this is thought for
175. 7:19some cosmonauts to be simply the first
176. 7:21Plateau on a light effect but far more
177. 7:24importantly the cognitive effects are
178. 7:25not due to DXM but rather its active
179. 7:27metabolite dextr or dextro Dex orphan
180. 7:30Dex orphan what is
181. 7:34that Dex
182. 7:36orphan is that I've never even heard of
183. 7:39that [ __ ] dexed
184. 7:41orphan
185. 7:43dxo oh boy that's crazy it's not
186. 7:47dextromethorphan dextrorphan I I didn't
187. 7:50even that's like so hard to say why
188. 7:51would they even name something that
189. 7:52that's like come on why would you do
190. 7:55that let's just call it dxo from now on
191. 7:57if we're going to if they're going to
192. 7:58talk about it
193. 8:01um let's see here uh here's the key
194. 8:04bupropion inhibits the conversion of DXM
195. 8:07to this metabolite buproprion happens to
196. 8:09slow this process uh by inhibition of
197. 8:12the d26 enzyme this is why this this
198. 8:15combination works so well it slows it
199. 8:17down to the point that no cognitive
200. 8:19effects of DXM are seen that makes sense
201. 8:22since in all clinical trials aity did
202. 8:24not cause dissociation when I consulted
203. 8:26with three separate psychiatrists they
204. 8:28all completely agree that there is no
205. 8:29way a trip off of this
206. 8:30anti-depressant now to my knowledge the
207. 8:32only approved anti-depressant that does
208. 8:34cause uh transient dissociation is
209. 8:37ketamine um did they approve that uh as
210. 8:40an anti-depressant I didn't know that uh
211. 8:42tldr aity does not cause dissociation
212. 8:45because of the way the drug is designed
213. 8:46it's possible uh any dissociation is
214. 8:49Placebo effect but physiologically
215. 8:51speaking or yeah physiologically
216. 8:53speaking it is not possible due the
217. 8:55biochemical mechanism of how the drug
218. 8:56was designed Source biologist self MD
219. 9:00Jong MD Bradley MD uh lilick Source
220. 9:05Jason ker MD understanding ofel all
221. 9:08right so what do people have to say so
222. 9:11someone said aity absolutely caused
223. 9:13dissociation for me when I started I
224. 9:14felt like I was on a low to moderate
225. 9:16dose of a psychedelic and was not in
226. 9:17control of my body and couldn't
227. 9:19comprehend anything it was absolutely
228. 9:21not Placebo and it was a startup side
229. 9:23effect I wasn't aware of it went away
230. 9:25after about a month the same time my
231. 9:27other side effects diminished such as
232. 9:28food repulsion and involuntary movements
233. 9:30involuntary movements starting ofel was
234. 9:33very rough on me it was worth it though
235. 9:34and has changed my life after 9 years of
236. 9:37medical trials with nothing helping a
237. 9:39ton aity has been a miracle I'm living
238. 9:41for the first time in my life so that's
239. 9:43a good things I'm they dissociated but
240. 9:45they ended up being good um someone said
241. 9:48it did this with me too I even did
242. 9:49things that I barely remembered doing
243. 9:50and definitely shouldn't have been doing
244. 9:52uh definitely shouldn't have been
245. 9:53driving excuse me it's a lot less uh
246. 9:55it's a lot less so the longer I've been
247. 9:57on it but it's definitely still slightly
248. 9:58dissociated for me also we're not
249. 10:01drinking Miller High Life tonight we're
250. 10:02drinking uh Black Rifle Coffee Company
251. 10:05espresso 300 milligram triple triple
252. 10:07shot 100% Colombian coffee so my brain
253. 10:10is working faster than um my mouth
254. 10:13movements so if I misread some [ __ ]
255. 10:16that's probably why because my brain is
256. 10:17just moving ahead while my while my
257. 10:19mouth is still behind so you know uh how
258. 10:23many more how many minutes we got on
259. 10:25here right now uh we're got we got 10
260. 10:27minutes so
261. 10:31so it's just it's just so interesting to
262. 10:34me like this just having this medication
263. 10:37like I I don't know for you guys like
264. 10:38that just like so so strange like I feel
265. 10:41like I'm on a live right now like I'm
266. 10:43not going to edit this out I'm just
267. 10:44going to keep on talking but um yeah no
268. 10:48it's uh it's so it's so weird
269. 10:51like man that that just comes to think
270. 10:54about like what else are they going to
271. 10:55come up with you know next if they came
272. 10:58up with this already you know like aity
273. 11:01bupropion and dextromethorphan like I
274. 11:04don't know both of those medications
275. 11:05scare
276. 11:06me and they put them together maybe two
277. 11:09negatives make a positive I mean there's
278. 11:11a lot of positive stories I um um so I
279. 11:15have a pos positive stories and I have
280. 11:17negative stories so the first one here
281. 11:19is a negative story this is from five
282. 11:20months ago um aity making me feel
283. 11:24awful hi there I'm wondering if anyone
284. 11:26could speak to their experience with the
285. 11:28side effects going away for the drug I
286. 11:29was on it for about a week and the side
287. 11:31effects gradually built until I felt so
288. 11:33dizzy and woozy it felt like I would
289. 11:34pass out when I did any exercise my
290. 11:37anxiety also greatly increased and I
291. 11:39felt like my vision was slightly blurred
292. 11:40as well I just felt sort of high the one
293. 11:44thing though was that I felt my
294. 11:45depression was getting better I got off
295. 11:47of it over the weekend and the side
296. 11:49effects went away fast forward to this
297. 11:51week my nurse practitioner recommended I
298. 11:53try AEL again and just push through the
299. 11:55side effects for what she says would be
300. 11:56about a week this time starting it
301. 11:58through the side effect effect started
302. 11:59out severe rather than building
303. 12:01yesterday I felt like I could barely
304. 12:03stand at the stove to cook an egg and
305. 12:04spent most of the day laying around at
306. 12:07uh at this point if I muscle through and
307. 12:09keep staying on this med I think I'm
308. 12:10going to have to take off a work as I
309. 12:12don't trust myself to be able to drive
310. 12:14safely does anyone think that this is
311. 12:16actually worth pushing through the week
312. 12:17of the side effects is there a chance
313. 12:19they'll go away thanks so much for any
314. 12:21input let's upvote that so you don't
315. 12:23read that again um someone said I was in
316. 12:27the exact same position as you I felt
317. 12:29awful on this drug when I doubled the
318. 12:30dose so I spoke to my doctor who
319. 12:32recommend going back on one a day before
320. 12:34bed for another 7 days then doubled the
321. 12:36dose after that I did this and while I
322. 12:39still felt a bit Spacey it wasn't nearly
323. 12:41as bad also I now take my meds in the
324. 12:43afternoon and evening 2: p.m. and 10:
325. 12:45p.m. this morning I feel super calm
326. 12:47which is not usual for me it's still
327. 12:49early days for me but I'm glad I took my
328. 12:51doctor's advice obviously everyone is
329. 12:53different but I hope this helps uh so
330. 12:56she said thank you so much I'm it sounds
331. 12:58like you had a pushed through about a
332. 12:59week of the side effects and then they
333. 13:01said yes my side effects were so bad I
334. 13:03thought about stopping but it seems to
335. 13:05be better after doing almost two weeks
336. 13:06with just one pill I tried well Butrin
337. 13:08in the past and it really didn't agree
338. 13:10with me so I think it's taking my system
339. 13:11longer to uh climatize to it um yeah
340. 13:16thanks so much for the information I'm
341. 13:17hoping that I can get over the side
342. 13:18effects too uh someone said I love aity
343. 13:22now since I added vilar Villar is uh the
344. 13:25trintellix I
345. 13:27think uh right
346. 13:32uh let me make sure here I don't want to
347. 13:34say it if it's
348. 13:36not no it's not okay vilar is not Cara
349. 13:40praising okay so I don't even is that on
350. 13:44aoid oh [ __ ] I already looked it
351. 13:49up so Villar yeah RAR is not TR why do I
352. 13:54think it was trintellix it's something
353. 13:56else um okay
354. 14:01so this person said hey all' I've been
355. 14:04on alel for about five months now when
356. 14:07first increasing the dose I had a very
357. 14:08hard time sleeping excessive sweating
358. 14:11and sexual side effects so after a month
359. 14:13of two pills I reduced it back to the
360. 14:14one pill per day I definitely felt a
361. 14:16decrease in efficacy over the next month
362. 14:18as well as a decrease in side effects so
363. 14:20I then went up to two pills again after
364. 14:23another month at two times per day all
365. 14:25side effects were gone but I also did
366. 14:26not feel the same efficacy as I did in
367. 14:28the first month the first month I was on
368. 14:30AEL I felt as if I was helping my
369. 14:32depression about 75% and now I feel like
370. 14:34it's maybe helping 10% I recently spoke
371. 14:37with my doctor about this and I just
372. 14:38started to add Abilify into the mix it
373. 14:40has been less than a week since I
374. 14:42started with the Abilify it has not
375. 14:43seemed to help much yet but it also had
376. 14:46but it also hadn't made hasn't made
377. 14:48things worse excuse me so I plan on
378. 14:49continuing with this for another month
379. 14:51or so to see if I get a boost the aity
380. 14:53and get back to 75%
381. 14:56relief I know the side effects when
382. 14:58starting anti-depressants can be awful
383. 14:59but but I encourage people to try to
384. 15:01push through as much as they can in the
385. 15:03beginning since there sometimes is
386. 15:04relief on the other side although it is
387. 15:07also okay to call it when enough is
388. 15:08enough and the side effects are too much
389. 15:10to bear please talk to your doctor about
390. 15:11Alternatives and take it from there
391. 15:13educate yourself and be your own biggest
392. 15:15Advocate demand the treatment you want
393. 15:17and feel is best for you peace and
394. 15:19wellness wishes to all here well that
395. 15:21was very nice thank you so much who said
396. 15:23that so intention no in 1993 is that
397. 15:26when you were born oh boy uh so yeah so
398. 15:31people are saying you got to push
399. 15:32through it stick with it uh because
400. 15:33people are saying it can work work out
401. 15:36uh so yeah uh most people are saying
402. 15:39that uh all right let's go to the next
403. 15:43page I got three more pages
404. 15:45here uh this now this is a positive
405. 15:47story is AEL responsible for the best
406. 15:50six months of my life I've suffered from
407. 15:53MDD and Gad for years and have had
408. 15:56limited success with anti-depressants
409. 15:58about a year ago I worked with my doctor
410. 15:59to get off Wellbutrin I didn't feel much
411. 16:01benefit from it anymore about a month
412. 16:04after I fell into a bad depression that
413. 16:05lasted the entire summer I really didn't
414. 16:07want to go back on anti-depressants and
415. 16:09was researching psychedelics for
416. 16:10depression I've experienced psychosis
417. 16:12before and the trippy stuff scares me
418. 16:14but through my research I learned about
419. 16:16alel I still had some well Butrin pills
420. 16:18so I bought cold pills from Amazon and
421. 16:20gave it a try it worked my depression
422. 16:22lifted very quickly I only took the
423. 16:24pills for about 2 weeks and quit I
424. 16:26started exercising meditating reduced my
425. 16:28alcohol intake significantly and lost 15
426. 16:30lbs I experienced the best 6 months of
427. 16:33my life I felt truly happy for the first
428. 16:34time that I could ever remember I
429. 16:37attributed it to my my new healthy
430. 16:38lifestyle however in recent weeks I
431. 16:40started feeling terrible again I'm doing
432. 16:42all the healthy things but the magic is
433. 16:44gone the optimism gone the frustration
434. 16:46is
435. 16:47intense okay that's a big 180 flip I
436. 16:50couldn't re really remember the research
437. 16:52I did on ability and started reading up
438. 16:54again I learned it works in a similar
439. 16:55way to ketamine I know the effect effect
440. 16:58effectiveness of ketamine treatments can
441. 17:00last months before another treatment is
442. 17:02needed is it possible that the best 6
443. 17:04months of my life was not the result of
444. 17:05healthy changes in my life rather it was
445. 17:07the lasting effects of only two weeks of
446. 17:09on on aity I guess I guess I'm going to
447. 17:12find out I just took a Wellbutrin and a
448. 17:13cold pill and I'm feeling hopeful that
449. 17:15maybe I can have have my happy life back
450. 17:18uh so I don't know what the like if you
451. 17:21were to take Wellbutrin and uh cold pill
452. 17:25I don't know how different that would be
453. 17:28compar compared to like you know
454. 17:29actually taking allity I don't know what
455. 17:32difference that would make I want to see
456. 17:33what people are
457. 17:34saying
458. 17:36um let's see here hi I was taking wbin
459. 17:41for a year before aity I was working out
460. 17:43daily lost 45 pounds cut back on alcohol
461. 17:45and was eating well still depressed
462. 17:47started ality six weeks 6 weeks ago and
463. 17:50I'm a th% mentally better it's the
464. 17:53ality
465. 17:56um let's see here except for a past
466. 18:00history of psychosis you could
467. 18:01essentially be writing my story I'm
468. 18:03convinced it's the dextromethorphan in
469. 18:04ovel because I've been on wbin for
470. 18:06around 3 years at 300 milligrams extent
471. 18:08a release and it wasn't enough on its
472. 18:10own I am hoping that my psychiatrist
473. 18:12will be on board because I can't afford
474. 18:13the brand name medication and I'm not
475. 18:15even sure if it's officially available
476. 18:16where I live yet yeah no it's I don't
477. 18:19even know how much it costs uh because I
478. 18:21I think it's expensive I think it really
479. 18:23is um but yeah no if you want to do it
480. 18:26yourself I don't know like I don't want
481. 18:28to like say anything because this is
482. 18:30like you know I don't know what can
483. 18:32happen to you I don't know if there's
484. 18:34like I really don't know the mechanisms
485. 18:36and stuff I'm not a doctor I'm not a
486. 18:38[ __ ] pharmacist I don't know um so
487. 18:41please don't I'm just reading these
488. 18:43stories I'm just trying to get this out
489. 18:44here because this is like a very
490. 18:46interesting thing to me and I want it to
491. 18:47be out here so yeah
492. 18:50um uh let's
493. 18:52see
494. 18:55um yay I love this I'm six months in and
495. 18:58I feel the same way
496. 19:02okay I'm ready to get on the aity do it
497. 19:05yourself bus I've been so depressed
498. 19:07since the ADHD Med sortage uh I can't
499. 19:10get my prescription anymore so the combo
500. 19:11of ADHD and depression is no fun thank
501. 19:13you for the post I'm on Wellbutrin going
502. 19:15to throw in 45 milligrams of
503. 19:17dextrin uh it's uh op says I'm on day5
504. 19:23got to keep in mind the placebo effect
505. 19:24but man the cloud is lifted also the
506. 19:26layer of anxiety on my chest that felt
507. 19:27so thick I could peel it off it Al is
508. 19:29also gone it's a damn Miracle I'll try
509. 19:32to remember to post another update in a
510. 19:33week good luck let me know if you get
511. 19:35similar results so I'm going to actually
512. 19:37open his page in a new tab and we're
513. 19:40going to see if he's posted
514. 19:42since uh oh boy he posts a
515. 19:47lot um he's 43 years old that's what he
516. 19:51says
517. 19:5443 I zoomed out on
518. 19:56accident um
519. 20:01[Music]
520. 20:02yeah I don't
521. 20:03[Music]
522. 20:05know let's see if they searched I'm
523. 20:08going to search aity in there yeah this
524. 20:11is just going to be like a weird video
525. 20:13just hang
526. 20:16out
527. 20:18uh no they didn't post it they posted
528. 20:21another [ __ ] subreddit
529. 20:26but I don't think they did uh
530. 20:29they didn't post
531. 20:31again
532. 20:33unfortunately so
533. 20:35yeah uh all right so this next one the
534. 20:40person who posted it is deleted one
535. 20:42month aity review You Could Read My
536. 20:45day-to-day update here um
537. 20:51okay
538. 20:53okay first dose today we'll update
539. 20:55update through the week um no we're not
540. 20:58going to read
541. 20:59that all right so soda preface 24 male
542. 21:03with treatment resisant depression Gad
543. 21:05ASD and ADHD in my two weeks on aity I
544. 21:08noticed immediate changes they were
545. 21:10subtle but I felt a fair amount of
546. 21:11Positive Vibes just a general good
547. 21:14well-being as the month progressed and
548. 21:16my dose increased I began to feel less
549. 21:18anxious more focused and definitely less
550. 21:20depressed I was able to put down bad
551. 21:22habits and incorporate many good things
552. 21:23in my life positive thinking body
553. 21:25positivity and acceptance the opposite
554. 21:28of catastrophizing okay all in all just
555. 21:31great feelings side effects I've
556. 21:33experienced though weight loss food
557. 21:35became optional at some point increased
558. 21:37libido amount of dirty thoughts
559. 21:39increased started flirting with
560. 21:40strangers and hooked up with one of not
561. 21:42with with one Not My Brightest idea okay
562. 21:46no difficulty with arousal erection
563. 21:48quality but it takes forever to climax
564. 21:51um yeah no I I think with the DXM I
565. 21:54don't know how it is on Wellbutrin but
566. 21:56DXM like I said I don't know it's it's
567. 21:58uh very very hard yeah no pun intended
568. 22:04uh the meds started to interfere with my
569. 22:06ADHD meds synergistic action when I
570. 22:08started feeling Euphoria for my usual
571. 22:09dose this went mostly away though mother
572. 22:12of all dry mouths as someone who drinks
573. 22:14exclusively water too pupil dilation and
574. 22:16light sensitivity mine are acti on my
575. 22:19hairline despite not having acne in my
576. 22:21teens and a very strange craving for
577. 22:23sunlight like just being in the sun felt
578. 22:25like he put an Italian Italian Emoji
579. 22:28like oh come you know hey [ __ ] you you
580. 22:31know decreased alcohol tolerance below I
581. 22:34will answer any questions and continue
582. 22:35to update on a bonly
583. 22:38basis uh
584. 22:41okay let's see here no one is
585. 22:46really uh wait this
586. 22:49person I'm I'm supposed to start taking
587. 22:52it I already have a hard time orgasming
588. 22:54the nurse in my doctor's office
589. 22:55convinced me that this wouldn't happen
590. 22:56that her sex life greatly improved with
591. 22:58it and yet I read a lot of comments like
592. 23:00this I was wanting to try well Butrin
593. 23:01because I hear so many good things about
594. 23:03it with ADHD but my doctor's office
595. 23:05basically pushed this one
596. 23:07instead oh
597. 23:10boy
598. 23:12um this person said I think this is this
599. 23:15is the reply to this person thank you
600. 23:17for taking the time to share I'm on day
601. 23:19six I also take ADHD medication ader all
602. 23:21I feel the opposite effects you do I
603. 23:23start yawning more lethargic I feel it's
604. 23:25blunting the Aderall which shouldn't
605. 23:27happen I should experience something
606. 23:28similar to you with a stronger longer
607. 23:30amphetamine effect however I have well
608. 23:32noticed some positives in Behavior Uh it
609. 23:35makes an orgasm nearly impossible for me
610. 23:37sigh these meds always have such
611. 23:38individual pros/cons to them yeah that's
612. 23:41true they all do you know it's it's you
613. 23:44got to find the one that's right for you
614. 23:45you know it could take a while you know
615. 23:48I don't even know if Lexapro is right
616. 23:49for me I don't even
617. 23:51know uh but
618. 23:55yeah uh let's see here I'm just trying
619. 23:57to see
620. 24:00someone said I love your honesty about
621. 24:02the dirty thoughts and oh my God feel
622. 24:03free to hook up as much as you want just
623. 24:05be safe let others live vicariously
624. 24:07through you yeah no worries and I will
625. 24:10LOL I went from AUD to quiet I went from
626. 24:13from Aude to quite promiscuous which is
627. 24:15kind of liberating and
628. 24:19interesting oh my god
629. 24:22um so it seems like a lot of people are
630. 24:25trying it themselves which I do not
631. 24:27recommend to do unless you have a
632. 24:29doctor's permission um I don't know how
633. 24:31it's going to affect you because you
634. 24:33know in one pill there's the DXM and
635. 24:36buproprion and but if you're doing it
636. 24:38separately like I really don't know I
637. 24:40really don't know I wish I could have
638. 24:41the answers but yeah um so I got one
639. 24:44more page here what's your experience on
640. 24:47aity been like uh so there's going to be
641. 24:49a couple experiences here hi everyone I
642. 24:52started taking AEL on Saturday and both
643. 24:55Saturday and Sunday I felt super loopy
644. 24:57actually a little high on Saturday I
645. 24:59felt nauseous and I thought that that
646. 25:00was due to having coffee and not eating
647. 25:02anything but after some Reddit reviews
648. 25:04I'm thinking it could have been from the
649. 25:05meds I reached out to my doctor and she
650. 25:07said try taking it at night before bed
651. 25:09so I did that last night Monday I had
652. 25:11some trouble going to sleep and was
653. 25:12maybe a little Restless I woke up this
654. 25:14morning Tuesday feeling a little dizzy
655. 25:16SLS Spacey so I went back to sleep for a
656. 25:18little I guess I'm trying to figure out
657. 25:20if this feeling is just a permanent
658. 25:22effect of the meds or does it eventually
659. 25:23go away after consistently taking it
660. 25:25what have your experiences been like
661. 25:27anyone else have experiences like mine
662. 25:29um to note the last few years I've been
663. 25:32on Wellbutrin and it worked really well
664. 25:33for me I also have taken Aderall on and
665. 25:35off for most of my life but my major
666. 25:37complaint is the anxiety and tenseness I
667. 25:38get from it so my doctor thought this
668. 25:40could be a good medication I've been off
669. 25:42all meds for almost 6 months up until
670. 25:44taking aity this weekend thanks so
671. 25:47much uh check your blood pressure I had
672. 25:49these same symptoms when I first started
673. 25:51end up being that the avity was
674. 25:52substantially raising my blood pressure
675. 25:54making me feel dizzy and
676. 25:56Spacey um okay
677. 26:00uh just chiming in sounds like my
678. 26:01experience too the first week I felt a
679. 26:03bit off a little bit off but when I uped
680. 26:05twice a day I was seriously loopy
681. 26:07paranoid and majorly dissociating out
682. 26:09of- body feelings I pushed through it
683. 26:11and thankfully it began subsiding a bit
684. 26:13after a few days after about a week or
685. 26:15so it got significantly better and I
686. 26:17didn't really notice it too much anymore
687. 26:19I do I do still get a bit of Spacey SL
688. 26:22dissociated feeling every once in a
689. 26:23while but I figured that it mostly
690. 26:25happens uh when I take it with my
691. 26:26Aderall and or strong coffee so I try
692. 26:28not to do that I also get some I will
693. 26:30also get some symptoms if I miss a few
694. 26:32days then restart overall if you're able
695. 26:34to push through it I would give it some
696. 26:36time to see if the symptoms subside it's
697. 26:38really been amazing for me and even
698. 26:39though the beginning was tough I'm glad
699. 26:40I stuck it out so a lot of people I've
700. 26:43noticed reading these people have had
701. 26:46bad symptoms at the beginning spacing
702. 26:48out feeling dissociation I don't know uh
703. 26:50that person said it was a lie I don't
704. 26:52know if that person was even a doctor a
705. 26:54biologist whatever he said he was um you
706. 26:56know I people people are experiencing
707. 26:59dissociation so it's not it's not just
708. 27:01you know Placebo or anything people are
709. 27:03actually experiencing this
710. 27:04[ __ ]
711. 27:06um someone said yes this was similar to
712. 27:09my initial experience my psych warned me
713. 27:11that I'd feel off for the first few days
714. 27:14and she said I could keep taking one a
715. 27:15day until I felt a bit more stable in
716. 27:17the beginning I kept saying I felt like
717. 27:19my body was having a panic attack but my
718. 27:21head was clear which actually end up
719. 27:22being kind of useful because I got to
720. 27:24practice some sematic tools to call my
721. 27:26body down since I had the presence of
722. 27:27mind do it about a week later I went up
723. 27:30to two and then I felt fine and then I
724. 27:32felt good and then I was like am I manic
725. 27:35or is this just what it's like to feel
726. 27:37happy and the real nice thing is I can
727. 27:39still feel it all I'm just much more
728. 27:41self-compassionate and patient while I
729. 27:43move through the feelings I keep
730. 27:44convincing myself that this good feeling
731. 27:46isn't real or that I somehow don't
732. 27:47deserve it because it's manufactured but
733. 27:49[ __ ] that I did the best that I could
734. 27:51for as long as I had until I got to this
735. 27:53part so I hope you're able to stick with
736. 27:55it and that you'll find a similar relief
737. 27:57the only negative side effect now have
738. 27:58is persistent ttis oh God which is
739. 28:01annoying but well worth it for the peace
740. 28:02in my brain is it really though
741. 28:05persistent ttis that sounds terrible I
742. 28:07don't know if I'd want
743. 28:09that I felt loopy and drugg for about
744. 28:11six loopy and drugged for about 6 to8
745. 28:14days after going to twice a day and then
746. 28:16almost like magic that high feeling
747. 28:18evaporated and now I just feel fine it's
748. 28:20the best sense of that word uh I had a
749. 28:23very similar experience to you when I
750. 28:24increased my dose to twice a day my
751. 28:25doctor told me to go back down to one a
752. 28:27day for two weeks until my body adjusted
753. 28:29I was totally fine after that with no
754. 28:31side effects and I've really had good
755. 28:32results with
756. 28:33AEL uh so um you know people are
757. 28:37starting with dosing maybe don't start
758. 28:39with two maybe just take one you know if
759. 28:41if they tell you to take two just start
760. 28:43off with one just so your body can get
761. 28:44used to it but uh yeah this is just for
762. 28:46people who are getting getting it
763. 28:48prescribed uh if anyone got this
764. 28:50prescribed please leave in the comments
765. 28:51section below like hey what what's your
766. 28:53experiences on it because I would love
767. 28:54to know um
768. 28:58it took me about a week before I stopped
769. 28:59feeling drugged from about uh hours two
770. 29:02to four after dosing I didn't feel it
771. 29:04come back when I increased it to two
772. 29:06doses uh this person said I was loopy
773. 29:08and Spacey for a few months but I've
774. 29:10adjusted now I couldn't pay attention in
775. 29:12meetings my words would slur the first
776. 29:13few weeks I also experienced hypotension
777. 29:16at times I had weird highs I would feel
778. 29:18sleepy it was a bit of a roller coaster
779. 29:20but I've been on it for like 10 to 11
780. 29:22months now and functioning
781. 29:24fine uh so yeah
782. 29:30uh the whole genocide so uh yeah I don't
783. 29:33know what country they're in uh so this
784. 29:35is the last one for about two weeks I
785. 29:38was experiencing intense and weird
786. 29:39anxiety which I was going to call it
787. 29:41quits but I decided to continue and
788. 29:43began taking two a day 8 hours apart I
789. 29:46started feeling better for lack of a
790. 29:47better word my motivation and passion
791. 29:49that I thought I lost for good return
792. 29:51prompting me to make significant changes
793. 29:53in my life including returning to school
794. 29:54at 33 fulltime this flush of positivity
795. 29:57did did not last long I could feel
796. 29:59myself start to fall apart again I've
797. 30:01been I have been on alel for about a
798. 30:03year now and last week I had to make a
799. 30:06decision to taper off and start back in
800. 30:07my Wellbutrin I hoping to one day be
801. 30:09able to try micro doing but for now back
802. 30:11to Wellbutrin and Zoloft depression is a
803. 30:14[ __ ] yeah depression is a [ __ ] [ __ ]
804. 30:16dude like [ __ ] why does it have to
805. 30:19exist man depression sucks [ __ ] I
806. 30:22hate it it just makes you feel dead like
807. 30:24depression people people who aren't
808. 30:26depressed don't understand depression is
809. 30:28like you don't you're not like sad you
810. 30:30just feel like you don't care you just
811. 30:32don't don't feel like life matters
812. 30:34anymore uh but I've noticed that anxiety
813. 30:37is worse like I'd prefer depression over
814. 30:40anxiety like if I had to choose one but
815. 30:42hey I got stuck with both so yeah um I
816. 30:45don't know I before when I was in high
817. 30:47school I wasn't like this I don't know
818. 30:49what happened I it it kind of happened
819. 30:51when I started at my job um but yeah I
820. 30:55don't know it sucks I wish zoff would
821. 30:58have worked well because it was working
822. 31:00well for me I was taking it and I was
823. 31:02feeling great but then that reading
824. 31:04problem happened and I couldn't take it
825. 31:06anymore so like it's like come on bro um
826. 31:09but yeah that was uh the video on ality
827. 31:12I hope you guys got some information on
828. 31:14it I thought that was pretty interesting
829. 31:16I've been wanting to do this actually so
830. 31:17I'm glad I finally [ __ ] did it um I
831. 31:19had another plan to do another video but
832. 31:22uh I I changed the plans of course uh
833. 31:24I'm not going to say what it is because
834. 31:25I'll probably do in the future uh so
835. 31:27yeah yeah uh I hope you all have a
836. 31:29wonderful day uh research this
837. 31:31medication see if you're interested in
838. 31:33it uh look it up more aity it's spelled
839. 31:36a u v l i t y but uh I'll probably put
840. 31:39in the title so you guys already see
841. 31:41that but uh yeah hope you all have a
842. 31:44wonderful day stay safe out there and
843. 31:47you know touch grass just go outside
844. 31:50exercise so you can get some good sleep
845. 31:56[Music]