AnatomySpecialSensesEarTasteSmellnew — Transcript
Full transcript
- 0:00Hello and welcome. Let's talk
- 0:04chemical senses. Let's talk chemical
- 0:06senses now. Let's go through and we're
- 0:08going to look at a couple of different
- 0:10senses.
- 0:11And here when we go through and we talk
- 0:13chemical senses, chemical senses we're
- 0:16going to look at are going to include
- 0:18the senses
- 0:19uh in relation to smell and uh the sense
- 0:22taste. So, let's go through and let's
- 0:24look at both of these senses there.
- 0:26Again, this is the anatomy, so we're
- 0:27going to go through and we'll check out
- 0:28the anatomy. Uh I'll hit at a little bit
- 0:30of the physio there, but it's nothing uh
- 0:32uh
- 0:33that you have to know or you're going to
- 0:34be responsible for knowing about or
- 0:36um you'll have to know in great detail.
- 0:38Um
- 0:38when you get to physio, then obviously
- 0:40you'll see that in greater detail when
- 0:41you get there.
- 0:42So, here let's move through. Let's get
- 0:45slideshow opened up. Let's play this
- 0:47from the current slide.
- 0:49All right. So, here we're going to go
- 0:51through and what uh talk about uh this
- 0:53first chemical sense, this first
- 0:54chemical sense will be uh the chemical
- 0:57senses of smell. Uh the the sense of
- 1:00smell.
- 1:01Now, when we go through and we talk
- 1:02about uh
- 1:03the sense of smell, the sense of smell
- 1:05is going to be elicited thanks to you'll
- 1:06see our olfactory epithelium. Thanks to
- 1:09our olfactory epithelium. Now, when we
- 1:11go through and we talk olfactory
- 1:12epithelium, this olfactory epithelium is
- 1:15going to be found occupying basically
- 1:18the olfactory mucosa. So, when we talk
- 1:20olfactory mucosa, the olfactory mucosa
- 1:22itself is going to be found now lining
- 1:25you'll see the roof. It says the roof of
- 1:27the nasal cavity here in your guys'
- 1:28slides. Um again now when we go through
- 1:31and we talk uh nasal cavity, we're going
- 1:33to talk specifically specifically
- 1:34speaking, we're going to see it's going
- 1:35to be found lining the superior nasal
- 1:37conchae on both sides. Lining the
- 1:39superior nasal conchae on both sides.
- 1:42So, here when we go through and we talk,
- 1:45you can see that there in greater detail
- 1:47now.
- 1:49Here you got the superior nasal conchae.
- 1:50We've talked about these nasal conchae
- 1:52when we talked bones. We referred to
- 1:54them as scroll-like structures. Okay?
- 1:57And then they've got meatuses, little uh
- 2:00canal-like uh passageways underneath and
- 2:02they're going to be involved with
- 2:03helping to create turbulence in the air
- 2:05that we breathe. So, here when we talk
- 2:07uh
- 2:08uh conchae, you can see all three
- 2:10conchae and we've got the superior
- 2:13our reference point for the sense of
- 2:15smell now.
- 2:17So, again, here we've got what we call
- 2:20our olfactory mucosa. The olfactory
- 2:21mucosa contains this olfactory
- 2:23epithelium. Let's look at this now in
- 2:25greater detail. Now, while we're here in
- 2:27this image, I want to point out to you
- 2:29as well um we're not going to just look
- 2:31at this one part and just talk about
- 2:32this and just you know leave this alone.
- 2:34I want you to look at everything, right?
- 2:35There's a picture, so I want you to go
- 2:36through the picture and look at
- 2:37everything there. Now, the sense of
- 2:38smell, the sense of smell is going to
- 2:41take place inside the nasal cavity. But
- 2:43now here you can see the nerve that's
- 2:45making its way to that nasal cavity is
- 2:48coming from you can see the cranial
- 2:49cavity. So, you've got a cranial cavity
- 2:52you can appreciate right in here.
- 2:54You've got then the nasal cavity. And
- 2:56then here you've got oral cavity. So,
- 2:58you got three different cavities I want
- 2:59you to be able to uh
- 3:01put together there as well. And then
- 3:02we're going to go through and we're
- 3:03going to look at uh all these other
- 3:05structures uh throughout the semester as
- 3:06well, but here you can appreciate one
- 3:09bone. You should know this bone here.
- 3:11Not only that, you should know this bone
- 3:12that you have here and you should see
- 3:14and be able to identify this bone you
- 3:15have here as well. So, not only that,
- 3:18but then we've got these bones down
- 3:19here. So, these are all going to be
- 3:21creating different boundaries. You could
- 3:23think of borders from one cavity to
- 3:25another. So, here we've got the sphenoid
- 3:27bone. Okay, here we've got the frontal
- 3:29bone. Between the two you've got the
- 3:31ethmoid bone. If you recall, we had the
- 3:35name of that
- 3:36structure uh that has the openings.
- 3:40Very good. I know you're all guessing it
- 3:42right. Cribriform plate with the
- 3:45olfactory foramina or cribriform
- 3:46foramina, right? Now, here you can see
- 3:50we've got
- 3:52which bone?
- 3:53Okay, we all know what bone that is. Uh
- 3:55it's got a specific name to it. Okay? Uh
- 3:59you would have want to know the name to
- 4:00that and then here we're going to have
- 4:01another bone that's going to help make
- 4:04up then the posterior 1/3 you could
- 4:06think of of that hard palate and that's
- 4:09going to be I'm 100% sure we all know
- 4:11the name of that bone there as well. But
- 4:14again, more specifically speaking,
- 4:15what's the name of that specific spot of
- 4:18that bone?
- 4:19Okay? So, here you can see then you've
- 4:22got basically that nasal cavity and
- 4:25we'll discuss the nasal cavity and its
- 4:26boundaries, borders, and all of that in
- 4:27greater detail when we get to
- 4:30uh respiratory system. So, looking here
- 4:33now, you can appreciate that olfactory
- 4:34epithelium. Now, this olfactory nerve
- 4:38we've got there, we've talked about that
- 4:39nerve there as well. We said this is
- 4:40cranial nerve number one. Here you can
- 4:42see it's got two parts to it. It's got a
- 4:44tract and then you can see the bulb
- 4:46part. I told you guys before, we'll look
- 4:48at the inside and we'll see what that
- 4:51is what that create what basically is
- 4:53helping to create that bulging part uh
- 4:56that bulb part of that nerve there as
- 4:58well when we move through
- 4:59excuse me through here.
- 5:01So, let's zoom in on that. When we zoom
- 5:03in on that region there, this is what
- 5:04you see.
- 5:06So, higher power
- 5:08this is what you've got there. Again
- 5:10now, let me reorient you to where we're
- 5:11at. You've got cranial cavity up in
- 5:14here.
- 5:15Cribriform plate of the ethmoid bone.
- 5:18And then right down here you've got
- 5:19nasal cavity.
- 5:22So, you can see here
- 5:23those tiny openings you've seen them
- 5:25when we talked bones and we went through
- 5:26all of that at the beginning of the
- 5:28semester.
- 5:29Let's talk then this olfactory
- 5:30epithelium. Now, when we talk olfactory
- 5:32epithelium, this olfactory epithelium
- 5:34you can see it's made up of a couple of
- 5:36different a few different cells. Now,
- 5:38the major cell type that we have here
- 5:40that we're going to talk about we're
- 5:41going to check out is going to be the
- 5:42olfactory sensory neurons or you can
- 5:45refer to them as the olfactory receptor
- 5:48cells. Now, when we talk about these
- 5:50olfactory receptor cells or these
- 5:52olfactory sensory neurons, you can see
- 5:55those cells here very nicely in yellow.
- 5:58These cells they're described they're
- 6:01described as being bowling pin-shaped
- 6:05cells. Bowling pin-shaped cells.
- 6:10They're found in that olfactory
- 6:12epithelium.
- 6:13This olfactory epithelium
- 6:17we said is found located high up in that
- 6:21nasal cavity in the roof of the nasal
- 6:23cavity covering the superior nasal
- 6:25conchae on each side of that nasal
- 6:26septum.
- 6:28So, that epithelium has got one major
- 6:30cell type here that we can see and
- 6:32that's the olfactory sensory neurons.
- 6:35Now, these olfactory sensory neurons
- 6:39So again, they're going to be found
- 6:40making up that epithelium
- 6:41which covers the superior nasal conchae.
- 6:44Now, these olfactory receptor cells,
- 6:46these olfactory receptor cells
- 6:48these cells you'll see they are number
- 6:50one, they're unusual bipolar neurons. If
- 6:53you recall, we talked about having
- 6:55bipolar neurons in a couple of different
- 6:57places. A couple of main places where
- 6:59I'd like you to know about and we've hit
- 7:01that now both of those.
- 7:04Next thing you can see each of these
- 7:05cells, each
- 7:07of these olfactory sensory neurons,
- 7:09these receptor cells, they have a thin
- 7:13apical dendrite. Here you can appreciate
- 7:16that thin apical dendrite. You can see
- 7:19that here for this neuron. Same thing
- 7:21same thing here for this one. Same thing
- 7:23here for this one. Here, here, and here
- 7:26as well.
- 7:27Now, these
- 7:29apical dendrites, these apical dendrites
- 7:31they're going to terminate. They
- 7:33terminate.
- 7:35They terminate as these widened-out
- 7:38knob-like structures.
- 7:41The dendrites, these thin apical
- 7:42dendrites, they're going to terminate as
- 7:44these
- 7:45widened-out
- 7:47knob-like structures you can see right
- 7:48here at the end.
- 7:50From which you're going to see several
- 7:52cilia radiate. From which you can see
- 7:55several cilia radiate. Now, this cilia,
- 7:59this cilia you'll see is going to be a
- 8:02little different from the cilia that
- 8:03we've talked about we've mentioned
- 8:04throughout the semester. Normally
- 8:06speaking, we've seen cilia to be erect.
- 8:08Here you see it's not erect. It's found
- 8:10lying flat against the epithelium.
- 8:13And also epithelia you can see there and
- 8:16when we talk cilia, we said cilia is
- 8:17going to help to move things along. So,
- 8:19here you see it's not helping to move
- 8:20things along. Here it's going to serve
- 8:22as we'll see here in a few seconds as a
- 8:24as basically the receptive area. So,
- 8:27let's talk olfactory cilia. That's next
- 8:29up on your note taker. Now, when we talk
- 8:31olfactory cilia, this olfactory cilia,
- 8:34what it does is it increases
- 8:37it increases the receptive surface area.
- 8:41It increases the receptive surface area.
- 8:45And again, like I said, you can see it's
- 8:46going to be found lying flat against
- 8:49it's found lying flat against that nasal
- 8:52epithelium.
- 8:57Against those epithelial cells.
- 9:00Against that olfactory epithelium.
- 9:08Now, here when we go through and we talk
- 9:11this cilia, you can see the cilia is
- 9:13also coated. It's also covered by a thin
- 9:15coat. It's covered by a thin coat of
- 9:18mucus.
- 9:20This mucus
- 9:22is a solvent.
- 9:24The mucus is a solvent and what this
- 9:26mucus does, it's going to capture it
- 9:29captures and it dissolves airborne
- 9:32irritants.
- 9:33It will capture and it will help
- 9:35dissolve airborne irritants.
- 9:43Now, when we go through and we talk
- 9:45mucus, this mucus is going to come from
- 9:48we can see these glands. Here we've got
- 9:51olfactory glands. These olfactory
- 9:53glands, they're They're to help produce
- 9:56the mucus
- 9:58along with the supporting cells.
- 10:00So, they'll produce the mucus along with
- 10:02the supporting cells.
- 10:04And these glands, they're found, as you
- 10:07can see, in the underlying connective
- 10:10tissue.
- 10:13They're found,
- 10:14excuse me, in the underlying
- 10:16connective tissue.
- 10:18So, you can see that right underneath
- 10:20here. Again, remember we talked
- 10:21epithelium, we said epithelium has got
- 10:23all these different characteristics. So,
- 10:25one of those characteristics is it's
- 10:26supported by connective tissue, and
- 10:28that's what you got right there.
- 10:31Now, here you can appreciate the gland.
- 10:34And here you got the the duct of the
- 10:37gland.
- 10:38And so, allow it to
- 10:41introduce its secretions to the surface
- 10:43or into a cavity. So, what type of a
- 10:45gland are we talking about here?
- 10:50Very good. That duct gave it away.
- 10:54You're talking about exocrine glands.
- 10:56Exocrine glands.
- 10:58So, next then let's move and let's talk
- 11:01then. The filaments, here you can see
- 11:03the filaments of olfactory nerve,
- 11:05cranial nerve number one. Here you can
- 11:07see now the filaments of cranial nerve
- 11:09number one. They're basically these
- 11:12slender
- 11:13unmyelinated
- 11:15axons. They are slender, unmyelinated
- 11:19axons
- 11:20of the olfactory receptor cells.
- 11:24Of the olfactory receptor cells.
- 11:28That are going to collect
- 11:30that are going to collect.
- 11:34You can see here and gather
- 11:38before they penetrate
- 11:42through the foramina. So, we talk
- 11:43filaments, filaments of cranial nerve
- 11:46number one, they're slender unmyelinated
- 11:49axons of the olfactory receptor cells
- 11:54that are going to collect and gather
- 12:00right before they penetrate
- 12:03through this cribriform plate via those
- 12:06olfactory foramina or cribriform
- 12:08foramina.
- 12:13Now, you can see these fascicles are
- 12:15going to these filaments basically,
- 12:16they're going to project superiorly.
- 12:19So, they project superiorly through
- 12:22the openings, through the foramina,
- 12:25cribriform foramina on the ethmoid bone.
- 12:30Now, I told you that olfactory
- 12:34nerve is going to have some subdivisions
- 12:36to it. We saw the tract, and then here
- 12:37we can see the bulb. Now, the bulb, you
- 12:39can see the inside. Now, the bulb is a
- 12:41widened out region, and you can see why
- 12:42it's widened out. It's widened out
- 12:44because you can see here we've got a
- 12:46junction.
- 12:47We've got a junction between
- 12:50the axon of one cell
- 12:52and the dendrites of another cell, from
- 12:55one neuron to another neuron. So, here
- 12:57what we have is we have these
- 12:59axodendritic
- 13:01synapses.
- 13:04Okay? Synapses
- 13:06where two cells come together. So, here
- 13:07you can see exactly that happening. Now,
- 13:10this cell here, multipolar
- 13:13cell, multipolar neuron, specifically
- 13:15speaking, it's a mitral cell.
- 13:18And now, these signals
- 13:20are going to be basically traveling
- 13:22in between these two cells, you can see.
- 13:29So, the olfactory bulb is basically
- 13:32found at the distal ends.
- 13:35It's the widened distal ends of that
- 13:38olfactory nerve, you can see right
- 13:39there.
- 13:41And then tract, I've given you the
- 13:42definition of tract.
- 13:45And so, that's exactly what you're
- 13:46seeing here.
- 13:52Now, we've got supporting cells here.
- 13:54These supporting cells are columnar
- 13:56cells. They are columnar cells.
- 13:59And they make up, you can see, they make
- 14:01up the majority.
- 14:02They make up the bulk. They make up the
- 14:05majority of this
- 14:07penny thin
- 14:09It's like as as as thin as a penny.
- 14:14So, again, they're going to be making up
- 14:16the bulk of this penny thin
- 14:19epithelial membrane.
- 14:21Now, this penny thin epithelial
- 14:23membrane.
- 14:27And then we can also see their basal
- 14:29cells. Basal cells are going to be
- 14:30dynamic stem cells.
- 14:38And so, here what happens then
- 14:40you've got the anatomy laid out here.
- 14:43What's going to happen is
- 14:47uh
- 14:48odorants. Odorants are going to come in.
- 14:50Excuse me, odorants will come in. And
- 14:52when odorants come in, odorants will
- 14:54dissolve in this mucus, and they'll go
- 14:56and they'll bind to receptors that are
- 14:58going to be found on the olfactory
- 15:00cilia. So, that's why I told you the
- 15:01cilia is a little bit different from the
- 15:03cilia that we've described before.
- 15:05So, these odorants come and they bind to
- 15:08these various receptors. And when they
- 15:10bind to the various receptors, then
- 15:11they'll excite these cells. These cells
- 15:14then will say get excited, they're going
- 15:16to start sending
- 15:17signals basically to the next cells,
- 15:18eventually letting
- 15:20the brain know what we have there that
- 15:22we're smelling.
- 15:24And then physio, you'll see we get into
- 15:26it in full on detail where you can
- 15:28actually see the receptors and the
- 15:31odorants, and you see the connection
- 15:32between the two help to activate a whole
- 15:35bunch of different uh uh
- 15:37you can think of activities inside the
- 15:40cell which are going to then allow us to
- 15:43be able to smell what we're smelling.
- 15:45Not only smell what we're smelling, but
- 15:47also to help create adaptation.
- 15:50So, you don't just keep smelling the
- 15:52same thing with that same intensity over
- 15:54and over. Right? If somebody comes
- 15:56with this new cologne, after a few
- 15:57minutes the initial
- 16:00you know, that initial smell is a pretty
- 16:02strong smell, but after that
- 16:05you know, you stop smelling it.
- 16:07And that's going to be due to
- 16:07adaptation. And you'll do different
- 16:09activities there as well where you'll
- 16:11try to see how long it takes for you to
- 16:14adapt.
- 16:17Next then let's move from
- 16:20sense of smell, we'll move to the next
- 16:22sense. This will be This will be taste.
- 16:24But let me go through the different
- 16:25processes that are taking place here.
- 16:27You can see now first the odorants will
- 16:29come in. The odorants come in and
- 16:30they'll bind to the receptor. Once they
- 16:32bind to the receptor, what's going to
- 16:34happen is they'll activate this G
- 16:36protein-linked receptor system which
- 16:39you can see here now this GTP gets
- 16:42activated. This olfactory protein gets
- 16:45basically gets activated, and it's going
- 16:47to activate now you can see adenylyl
- 16:49cyclase. So, there's an enzyme here.
- 16:52This enzyme, what it does then it
- 16:54converts ATP
- 16:56to cyclic AMP.
- 16:58Now, cyclic AMP then what it does, it
- 17:00goes and it binds to
- 17:03these receptors.
- 17:05These channel receptors.
- 17:08When it binds to these channel receptors
- 17:10now, here you can see what it does, it
- 17:11helps to open up that gated cation
- 17:15channel.
- 17:17And you'll learn and you'll see when
- 17:18these ions move across the membrane, if
- 17:20you haven't learned in 107, right? When
- 17:22you talk action potentials, you'll see
- 17:24this in physio and you'll get this down
- 17:25there. This will help to create then an
- 17:27action potential.
- 17:30As you can see here
- 17:32leading to the first part,
- 17:33depolarization.
- 17:35So, the cell depolarizes
- 17:38when that sodium is going to rush into
- 17:40the cell.
- 17:46Now, when we go through and we talk
- 17:47about the sense of smell, I want you
- 17:49guys to know this uh is one of the
- 17:51senses where signals are not going to
- 17:54pass through the thalamus.
- 17:56They do not pass through the thalamus.
- 17:59Okay? Before stimulating the primary
- 18:01olfactory cortex. Everything else we've
- 18:03seen, we said that the thalamus is going
- 18:04to serve as our
- 18:07relay station.
- 18:09It serves as our relay station. So,
- 18:11since it serves as a relay station
- 18:13for we said also incoming signals.
- 18:16So, here you can see is where one sense
- 18:19is not going to be sending in signals
- 18:21through the thalamus.
- 18:23So, secondary areas are going to include
- 18:25then you can see insula
- 18:28the orbital frontal cortex, hippocampus,
- 18:31amygdala, and the hypothalamus.
- 18:39And then here you can see all those
- 18:40passageways.
- 18:50Let's talk gustation. Let's talk taste.
- 18:52Now, when we talk gustation, we talk
- 18:54taste. Taste is going to take place
- 18:56inside the oral cavity, more
- 18:58specifically speaking, on the tongue.
- 19:00And we'll see other areas in that oral
- 19:02cavity as well. Most we'll say primarily
- 19:05inside the on the tongue because on the
- 19:07tongue is where we're going to find
- 19:09taste buds.
- 19:11And that's where the sense of taste is
- 19:13going to occur. So, taste buds, tongue
- 19:15is going to have most of them. There's
- 19:17some that are going to be found in the
- 19:18soft palate, the pharynx, the
- 19:20epiglottis, and also the cheeks as well.
- 19:22So, that's why I said primarily tongue.
- 19:26Now, these papillae we're going to go
- 19:28through and we're going to check out are
- 19:29going to be various papillae. Now,
- 19:32they're referred to as your lingual
- 19:33papillae.
- 19:35They're going to be projections on the
- 19:37surface of the tongue. Now, you can see
- 19:39there's various types. We have
- 19:41fungiform, we have foliate, we have
- 19:45vallate or circumvallate,
- 19:47and we have filiform.
- 19:50Filiform have no buds inside of them.
- 19:53They have no taste buds. They're going
- 19:54to be involved with basically uh
- 19:58we're going to talk about them in
- 19:59digestion. Okay, we're going to see that
- 20:01they're going to be involved with
- 20:02helping to basically uh
- 20:05uh give us a little bit of texture kind
- 20:07of taste there. And um they'll be
- 20:09involved with uh kind of helping to
- 20:11manipulate food basically.
- 20:13Now, the other three we can see here,
- 20:15they're going to have taste buds. The
- 20:17foliate, they're going to be basically
- 20:20containing buds in children. We can see
- 20:22them the fungiform will have buds there
- 20:23and then the valley will have buds there
- 20:25as well. We're not going to go through
- 20:26every single one of them. What we'll do
- 20:28then is we'll look at you can see now
- 20:30the various types. First here we've got
- 20:32the fungiform. Fungiform now we're going
- 20:35to see are going to be found scattered
- 20:37over the entire tongue surface.
- 20:39The fungiform are going to be scattered
- 20:42over the entire tongue surface and they
- 20:45are mushroom shaped.
- 20:48They are mushroom shaped papillae.
- 20:57Next up we have our foliate papillae.
- 20:59Foliate papillae are going to be found
- 21:01on the lateral aspects of the tongue.
- 21:03Found on the side walls.
- 21:07Found on the side walls.
- 21:10And then we have our vallate or
- 21:11circumvallate papillae.
- 21:14So taste buds
- 21:16you can see
- 21:18fungiform and foliate and then we said
- 21:21here
- 21:24fungiform, foliate and then the third
- 21:27the vallate or circumvallate they're
- 21:28also known as as well. So circumvallate
- 21:32found forming an inverted V.
- 21:35Found forming an inverted V at the back
- 21:38of the tongue.
- 21:39There's about 7 to 12 of them. About 7
- 21:42to 12 vallate or circumvallate papillae
- 21:46found forming an inverted V
- 21:51at the back of the tongue.
- 21:58So let's look at one one of their
- 22:00structures. Here we can see the
- 22:02circumvallate.
- 22:03So here you can see right on the sides
- 22:06you've got these taste buds. So what
- 22:08we'll do is we'll look at one of those
- 22:09taste buds
- 22:13and we'll examine that in greater
- 22:14detail. So let's move from this picture
- 22:16over to this picture here as well. So
- 22:18here now when we look at the structure
- 22:19of a taste bud, you can see they're
- 22:22going to be made up of gustatory cells
- 22:24or your taste cells.
- 22:27Now these are types of epithelial cells.
- 22:31These are types of epithelial cells and
- 22:33you can see they're going to be found
- 22:34making up the majority of
- 22:37these taste
- 22:39receptors. These
- 22:41taste buds
- 22:42we can say there.
- 22:45All right, so talking about these
- 22:47gustatory cells, you can see these
- 22:49gustatory cells are going to be found
- 22:51distributed among some supporting cells.
- 22:53So some of these cells will be
- 22:54supporting cells and other cells will be
- 22:56gustatory taste cells.
- 22:58Now these gustatory cells or these taste
- 23:00cells, they're epithelial cells. They're
- 23:03type of epithelial cell and you can see
- 23:04they're going to make up the taste bud
- 23:05along with supporting cells. Now we
- 23:09talked these uh
- 23:10gustatory cells. These gustatory cells
- 23:12now we can find these uh
- 23:15gustatory cells basically you can see
- 23:17here and we've got these nerve fibers
- 23:19coming in. Then they'll be penetrating
- 23:21basically and innervating uh these
- 23:25gustatory cells. So whenever those
- 23:26gustatory cells get excited, those
- 23:28gustatory cells are going to stimulate
- 23:29basically those cranial nerve fibers and
- 23:31then sending signals to you know, then
- 23:34basically to the cortices to just sum
- 23:36that up real quick. Now again, I was
- 23:38going to say to the different nerves. So
- 23:40depending on which part of the tongue
- 23:42you're at, so it'll be that specific
- 23:43nerve and then eventually making its way
- 23:45to the brain. Now
- 23:47here when we go through we look at one
- 23:48of the
- 23:50one taste bud and we look at its
- 23:51structure. Now I want you guys to see
- 23:53here what we can see is we can see first
- 23:55a taste pore.
- 23:56Now here we've got a taste pore. The
- 23:59taste pore is going to be an opening.
- 24:01It's a neck-like opening. It's a
- 24:04neck-like opening
- 24:05to each of the taste buds and it's going
- 24:08to allow now those tastants that are
- 24:10going to be coming making their way in
- 24:12with saliva basically allowing them to
- 24:15make their way into the sensitive the
- 24:17receptor portion which we're going to
- 24:19see is going to be the gustatory hairs.
- 24:23So the taste pore is going to be
- 24:24important
- 24:26because it's going to allow the tastants
- 24:28to make their way
- 24:30and come into contact now with those
- 24:33gustatory hairs.
- 24:35The receptive portion.
- 24:38Next in here we also have our gustatory
- 24:39hairs. So when we talk gustatory hairs,
- 24:41these gustatory hairs are long
- 24:44microvilli.
- 24:46They're going to be long microvilli.
- 24:50And you see the same thing right inside
- 24:52of here as well. They are long
- 24:54microvilli.
- 24:56They're long microvilli that are going
- 24:57to be found projecting from the tips
- 25:00of all gustatory cells. They're found
- 25:04projecting from the tips. You can see of
- 25:06all of those gustatory cells.
- 25:11Again, they are the sensitive portion.
- 25:14They are the sensitive portion. They
- 25:16contain basically the receptor membrane.
- 25:19So that is
- 25:22what the tastants are going to come and
- 25:23bind to.
- 25:27Then again you can appreciate those
- 25:29taste cells.
- 25:31And you can see how then they are
- 25:32innervated.
- 25:35And then as soon as they get excited
- 25:37they will then send signals along these
- 25:40sensory nerve fibers.
- 25:43Then physio you guys will do a lab and
- 25:44you'll see the importance of saliva. Now
- 25:47without saliva there it takes
- 25:49you'll see tasting is close to
- 25:51impossible basically because the saliva
- 25:54is there to help guide take basically be
- 25:56the medium take this tastant to the
- 26:00sensitive portion.
- 26:03Now again you also have basal cells here
- 26:05as well. Again, dynamic stem cells.
- 26:10So dynamic stem cells they differentiate
- 26:13and divide into new gustatory cells.
- 26:17And then taste fibers cranial nerve
- 26:18fibers is what you see there and then
- 26:20depending on which uh part of the tongue
- 26:22you're on, right? Or which part of the
- 26:24oral cavity you're at then
- 26:26uh because if we talk tongue, you got
- 26:28the anterior 2/3, the posterior 1/3 or
- 26:30uh the anterior uh
- 26:32uh 2/3, posterior 1/3 and then you've
- 26:34got the most dorsal portion and the
- 26:36pharynx included there as well, the
- 26:38epiglottis. Again, that's going to
- 26:40contain uh some of these uh taste buds
- 26:43there as well.
- 26:44So we talk taste
- 26:46in the oral cavity.
- 26:51Let's move then from taste. Let's move
- 26:53over to
- 26:55we'll see hearing. Before we jump down
- 26:58here you can appreciate the pathway now.
- 27:00So here you can see this pathway for the
- 27:03sense of taste is going to make its way
- 27:06right through the thalamus and then
- 27:08eventually to the specific areas of the
- 27:11cerebral cortex.
- 27:15Now we've talked about those specific
- 27:17areas
- 27:18already when we talked uh the cortices.
- 27:23So let's move then to
- 27:25hearing. Here you can see all the
- 27:26different nerves I told you you'll be
- 27:28responsible for knowing about there as
- 27:29well.
- 27:33Let's talk hearing. Let's talk ear.
- 27:36Now we talk ear. Ear you can see here
- 27:38this is a picture depicting the external
- 27:40ear or one part of the external ear. Now
- 27:43when we go through we talk ear, we'll
- 27:45look at the ear in a greater
- 27:48uh idea basically we'll get a greater
- 27:49greater idea of the ear when we look at
- 27:51this picture here. So here you can see
- 27:53and appreciate the ear in its entirety.
- 27:55Now here we go through we talk about the
- 27:57ear. You can see the ear is going to be
- 27:58get divided up into three different
- 28:00parts. You've got an external ear,
- 28:01you've got a middle ear and then you've
- 28:02got the internal ear. Now let's go
- 28:04through and let's talk each of these
- 28:06divisions one by one first. So here
- 28:09first we'll start with external ear. Now
- 28:11we talk external ear, the external ear
- 28:12is going to consist of a couple of major
- 28:14parts. You've got first the auricle
- 28:17which you can see right outside of here
- 28:19and then here we've got the external
- 28:20acoustic meatus. So these two main parts
- 28:23are going to make up what we call our
- 28:25external ear. So again, it consists of
- 28:27the auricle and the external acoustic
- 28:30meatus.
- 28:31First let's talk auricle. When we talk
- 28:33auricle, the auricle is what we call the
- 28:37ear in layman's terms, right? We say
- 28:38ear, we refer to this as the ear.
- 28:41Uh now you can see that that's just one
- 28:43part of the ear. This auricle is a shell
- 28:47shaped projection.
- 28:51It's a shell shaped projection.
- 28:53It's also known as the pinna. You can
- 28:56see here the pinna.
- 29:00This shell shaped projection is found
- 29:05surrounding the opening. It's found you
- 29:09can see surrounding
- 29:12the opening
- 29:14which is the external acoustic meatus.
- 29:18So what this auricle or this pinna does
- 29:21is a shell shaped projection. It's going
- 29:23to help kind of funnel sound into that
- 29:26opening into the external acoustic
- 29:28meatus.
- 29:30What type of uh
- 29:32cartilage are we talking about here?
- 29:35Very good. Elastic. Remember it's easy.
- 29:38It's elastic. Makes up the ear.
- 29:41And
- 29:43good job. The epiglottis. Very good.
- 29:46So here now when we go through we talk
- 29:48uh
- 29:49Oracle. You can appreciate that Oracle
- 29:51there. Now, in relation to the Oracle
- 29:52itself, we've got a few parts, but not
- 29:55just to the Oracle, but you can see to
- 29:57the external ear there as well. Let's go
- 29:59through these different parts here. Here
- 30:01you can first appreciate the helix, the
- 30:04helix. Now, the helix is the is the is
- 30:07is thick. It's the thickened rim you
- 30:10could think of. It's the thickened rim
- 30:16All right, of that Oracle. It's a
- 30:17thickened rim of the Oracle.
- 30:21This helix
- 30:22is going to
- 30:24project inferiorly
- 30:27to give rise to the lobule to the
- 30:29earlobe, to the lobule.
- 30:35Lobule is the fleshy
- 30:38dangling
- 30:40structure, fleshy dangling structure,
- 30:44and you can see here
- 30:46adipose.
- 30:49And then connective basically connective
- 30:51tissue
- 30:52support for the epithelial tissue right
- 30:55on top.
- 30:59Next here you have your tragus.
- 31:03Tragus
- 31:04you can see
- 31:06is going to help protect
- 31:08that external acoustic meatus, that
- 31:10opening. It's going to help protect that
- 31:11opening.
- 31:14Tragus is often pierced.
- 31:20And then here across from the tragus, we
- 31:22can appreciate the anti-tragus.
- 31:26Both again helping to block off that
- 31:28entrance into the ear.
- 31:33And then we've got the antihelix.
- 31:36So, first we talked helix. We can see
- 31:39across from the helix we've got our
- 31:40antihelix.
- 31:44So, anti usually you can see is across
- 31:46from the structure it's named for.
- 31:50And then here we've got the triangular
- 31:52fossa. You can see right above the
- 31:54antihelix.
- 31:57Triangular fossa.
- 32:02And then we've got the concha
- 32:04on the other side.
- 32:08So, it's when you
- 32:10stick your finger into your ear without
- 32:12sticking it into the external acoustic
- 32:13meatus. So, all of this is all the
- 32:16concha.
- 32:17The concha.
- 32:20You can see that. I don't know why I'm
- 32:21showing it to you on me. You can see it
- 32:22clearly in the picture.
- 32:24Concha.
- 32:26And then you got that opening, the
- 32:27external acoustic meatus.
- 32:30This external acoustic meatus is also
- 32:32known as the auditory canal.
- 32:35AKA
- 32:37auditory canal.
- 32:40It's a very short
- 32:42curved
- 32:44It's a very short curved tube.
- 32:49And it's going to extend from the Oracle
- 32:52to the eardrum.
- 32:56Believe it or not, there's a wrong way
- 32:58and a right way to put your stethoscope
- 33:00into your ear. If you don't know what
- 33:02you're doing and uh you don't uh check
- 33:05your uh technique, you can end up
- 33:08placing your stethoscope into the
- 33:09concha. If you place it in the concha,
- 33:12now there's no receptors here for
- 33:14hearing.
- 33:15So, you have to make sure you push the
- 33:17ear buds away from you so that way they
- 33:20follow the contour of that external
- 33:23acoustic meatus.
- 33:26Your teachers can tell just from the way
- 33:29you put your stethoscope into your ear
- 33:31whether you know what you're doing with
- 33:32the stethoscope.
- 33:34So, here you can see those sound waves
- 33:36are going to get funneled thanks to that
- 33:37external acoustic meatus into the
- 33:40tympanic membrane.
- 33:41So, they're going to pass through that
- 33:42external acoustic meatus and they're
- 33:45going to come in and they're going to
- 33:45stimulate that tympanic membrane.
- 33:49So, if you stick that uh stethoscope
- 33:51into the concha
- 33:53uh it's difficult to hear what you're
- 33:55trying to listen to.
- 33:56Especially those sounds, the sounds of
- 33:58the heart or the sounds of the abdomen
- 34:00or the sounds of the lungs already uh
- 34:02sometimes pretty faint in some
- 34:03individuals.
- 34:07So, external acoustic meatus you can
- 34:09appreciate there. Now, this external
- 34:10acoustic meatus
- 34:12is going to lead us to the eardrum as we
- 34:14described, to the tympanic membrane.
- 34:16Now, within this external acoustic
- 34:18meatus you're going to be able to
- 34:19appreciate ceruminous glands, right?
- 34:21We've talked about these glands before.
- 34:23Now, ceruminous glands are going to be
- 34:24modified apocrine glands. They are
- 34:27modified apocrine glands.
- 34:32Modified apocrine sweat glands, you can
- 34:35say more specifically.
- 34:38Modified apocrine.
- 34:44Now, these glands, they're going to
- 34:46secrete a yellow-brown
- 34:49waxy material called cerumen.
- 34:55So, they secrete a yellow-brown waxy
- 34:57material called cerumen or earwax.
- 35:00And earwax is important. Earwax is
- 35:03important because earwax is going to
- 35:04provide as a sticky trap.
- 35:09It will act as a sticky trap
- 35:12and help keep foreign bodies and also
- 35:14help repel insects.
- 35:17Doesn't always happen. I've removed uh
- 35:20cockroaches, toys even from
- 35:25people's external acoustic meatus, from
- 35:27children to adults.
- 35:30And uh wax I can't begin to tell you how
- 35:33many times.
- 35:38Now, we've got the tympanic membrane
- 35:40there next. The tympanic membrane is
- 35:41also known as the eardrum. The tympanic
- 35:44membrane you can see is going to serve
- 35:45as the boundary. It's going to serve as
- 35:46the boundary between that external ear
- 35:49and the middle ear. So, it's the border
- 35:51between the external and the middle ear.
- 35:58Let's move then to the middle ear. Here
- 36:00you can appreciate the middle ear, but
- 36:02what we'll do is we'll zoom in on the
- 36:04middle ear. And we zoom in on the middle
- 36:06ear, we're going to be able to
- 36:07appreciate its structures in greater
- 36:10detail. So, here you can appreciate its
- 36:11structures then in greater detail. Now,
- 36:13here first we've got the middle ear. The
- 36:16middle ear I'd like you to know is also
- 36:17going to be known as the tympanic
- 36:19cavity. AKA tympanic cavity. It's a
- 36:22small air-filled It's a very small
- 36:26air-filled
- 36:29mucosa-lined
- 36:32cavity.
- 36:35It's found in the petrous portion of the
- 36:37temporal bone.
- 36:39In that petrous portion of the temporal
- 36:41bone.
- 36:45Tympanic membrane we've already
- 36:46discussed there. You can appreciate now
- 36:48a round window and an oval window. The
- 36:51round window and the oval window are
- 36:53going to be openings.
- 36:55They're openings on the bony wall
- 36:58that lead us to the internal ear.
- 37:01Openings on that bony wall of the middle
- 37:04ear
- 37:05that will lead us to the internal ear.
- 37:09Now, the oval window you can appreciate
- 37:11underneath the stapes. So, here you've
- 37:13got the stapes, one of the bones, the
- 37:16ossicles we'll discuss in the middle ear
- 37:17here in a few minutes.
- 37:19Round window
- 37:21or oval window and round window you can
- 37:23see here inferior to the stapes.
- 37:28So, right underneath it
- 37:30you've got that oval window. So, deep to
- 37:33the stapes the oval window. And then
- 37:34here you can appreciate just inferior to
- 37:36it you've got the round window. So, this
- 37:38oval window is covered by the stapes.
- 37:39Now, the round window is covered by
- 37:42membrane. It's going to be covered by
- 37:44membrane. This membrane is going to be
- 37:46basically a membrane that's going to act
- 37:48like a valve. What's going to happen is
- 37:50when the stapes hits up against that
- 37:52oval window, that's going to help to
- 37:53create a a wave of basically a movement
- 37:57of fluid inside that ear. And that
- 37:59movement of fluid is going to happen
- 38:02efficiently if that round window is
- 38:05flexible and if it acts like a valve and
- 38:07allows basically that motion within the
- 38:11fluid to
- 38:12occur, we're going to be able to then
- 38:14hear the sound. So, we'll check all that
- 38:16out as we progress. So, I want you to
- 38:18know there going to be two openings.
- 38:20However, they're covered you can see.
- 38:25Next that we have our pharyngotympanic
- 38:27tube. The pharyngotympanic tube or the
- 38:30auditory tube, formerly known as the
- 38:33Eustachian tube.
- 38:35If you're old school, we used to refer
- 38:37to it as the Eustachian tube.
- 38:41It runs obliquely. It's found running
- 38:43obliquely. It runs obliquely downward.
- 38:46And it's going to link the middle ear.
- 38:49It will link that middle ear cavity you
- 38:51can see here.
- 38:53It will link that middle ear cavity to
- 38:56the pharynx.
- 38:57To more specifically speaking, you'll
- 38:58see the nasopharynx.
- 39:01To the nasopharynx. Now, when we get to
- 39:03when we get to digest No, we get to
- 39:05respiratory. We get to respiratory,
- 39:07we're going to look at the other end.
- 39:10We're going to see where it opens up at
- 39:11inside that nasopharynx.
- 39:16So, you can see here when we go up and
- 39:17down the hill, we want to equalize the
- 39:19pressure, right? We'll usually plug our
- 39:20nose and that's what that uh helps us to
- 39:23do basically there.
- 39:26Let's talk then. Next we've got our
- 39:28auditory ossicles. When we talk auditory
- 39:30ossicles, they are three of the smallest
- 39:33bones in the body.
- 39:34They're found in this tympanic cavity.
- 39:38And they're going to be named according
- 39:40to their shape. They will be named
- 39:43according to their shape.
- 39:46And uh question we can formulate here is
- 39:49uh which skeletal division do they
- 39:51belong to?
- 39:54Very good.
- 39:56I know you got that right, axial.
- 40:01So here we can see first we've got the
- 40:03malleus. Malleus is hammer-shaped.
- 40:08Malleus is going to be found you can see
- 40:11one end of it articulating with the
- 40:13tympanic membrane and the other end and
- 40:15you can see articulating with the next
- 40:17bone in line which is going to be the
- 40:20incus. Now the incus is anvil-shaped.
- 40:25It's anvil-shaped.
- 40:28We talk anvil-shaped, you can appreciate
- 40:30that they're very well. It's uh
- 40:32basically the structure that blacksmiths
- 40:35bend metal on and uh do work on.
- 40:38Or a wrestler from WWF if you remember.
- 40:43Next then we have our stapes. The stapes
- 40:46stapes stirrup-shaped
- 40:50stirrup-shaped.
- 40:52And you can see here it's going to be
- 40:53articulating with the incus on one end
- 40:56and then it's covering that oval window
- 40:58on the other end.
- 41:01So three of the smallest bones
- 41:05you'll find in the body.
- 41:08Next then let's move to the internal
- 41:11ear. Let's move to the internal ear. Now
- 41:14when we talk internal ear
- 41:19All right, so here we can see that
- 41:21internal ear. Now we talked this
- 41:23internal ear
- 41:26we can see
- 41:28it's also going to be known now as the
- 41:30labyrinth. Internal ear will also be
- 41:33known as the labyrinth. If you look up
- 41:35the definition labyrinth it's tortuous
- 41:36maze right and so forth. So here when we
- 41:40talk now this labyrinth this internal
- 41:41ear this internal ear is going to be
- 41:43found lying deep. It's found lying deep
- 41:45in the temporal bone behind the eye
- 41:47socket. Found deep in that temporal bone
- 41:52behind the eye socket. Now
- 41:55this internal ear is going to get
- 41:56divided up into two different parts into
- 41:57two different parts. Now to be able to
- 41:59appreciate these two different parts
- 42:00what we'll do is we'll move over to this
- 42:02picture here.
- 42:03Now in this picture here you can
- 42:05appreciate the bony labyrinth and then
- 42:07you can see within the bony labyrinth is
- 42:09the membranous labyrinth. So first off
- 42:12let's talk bony labyrinth. Now when we
- 42:14talk bony labyrinth the bony labyrinth
- 42:16is going to be this tortuous maze type
- 42:19pathway.
- 42:21It's a system you can think of of
- 42:23tortuous channels
- 42:25that's worming
- 42:28through the bone.
- 42:32So it's a
- 42:33you can think of carved out part inside
- 42:35the bone.
- 42:37It's going to be filled with a fluid.
- 42:39The fluid it's going to be filled with
- 42:40is called perilymph.
- 42:43Now this perilymph
- 42:45is a fluid that's going to fill this
- 42:48bony labyrinth. It fills this bony
- 42:50labyrinth and this perilymph is a fluid
- 42:53that's similar to and continuous with
- 42:57CSF.
- 43:03Next we have the vestibule. So here
- 43:05we'll move back. Now we move back here
- 43:08you can actually appreciate the
- 43:09vestibule
- 43:10and coming back here you can see the
- 43:13vestibule then in greater detail.
- 43:16So moving back when we talk vestibule
- 43:18the vestibule is a central egg-shaped
- 43:21cavity of the bony labyrinth.
- 43:26Within the sac within this uh vestibule
- 43:30we're able to appreciate the saccule
- 43:34and the utricle. So here's the utricle
- 43:37and here's the saccule within
- 43:42the vestibule. All within the vestibule.
- 43:44Now
- 43:46why is the saccule and the utricle
- 43:47important? Because we'll see within them
- 43:49are going to be the maculae
- 43:51our maculae and we'll talk about our
- 43:54maculae in a few minutes. So saccule
- 43:57first. Saccule is the membranous
- 44:01labyrinth sack.
- 44:04It's a membranous labyrinth sack.
- 44:10As is the utricle so utricle also a
- 44:15membranous labyrinth sack
- 44:19and they're both suspended
- 44:21in the perilymph.
- 44:24Right? They have perilymph around them.
- 44:26They're suspended within perilymph. And
- 44:28the reason why the saccule and the
- 44:30utricle are important because they
- 44:31contain the maculae. The maculae are
- 44:33going to be equilibrium receptors.
- 44:36They are our equilibrium receptors.
- 44:42Let's move then to the semicircular
- 44:44canals. So here you can appreciate the
- 44:46semicircular canals. And now within
- 44:48those canals you can see are the
- 44:49semicircular ducts.
- 44:52Within the canals are the semicircular
- 44:53ducts.
- 44:54Now when we talk semicircular canals
- 44:57semicircular canals are going to be
- 44:59found lying posterior and lateral to the
- 45:02vestibule.
- 45:04Lying posterior and lateral to the
- 45:07vestibule.
- 45:10And they're important because they
- 45:12contain the semicircular ducts.
- 45:17These ducts now
- 45:19you can see have these ampullae to them.
- 45:22The ampulla.
- 45:24The ampulla is going to be the enlarged
- 45:27swelling.
- 45:30It is the enlarged swelling at the end
- 45:34of the semicircular ducts.
- 45:37So you can see one here for this
- 45:40anterior duct
- 45:42you can see the same thing here for this
- 45:44lateral
- 45:45duct and we're going to have the same
- 45:46thing right back here for this posterior
- 45:48semicircular duct.
- 45:52The ampullae
- 45:53are important because the ampullae are
- 45:54going to be receptors as well. Also
- 45:57equilibrium receptors.
- 46:01So let's discuss the membranous
- 46:03labyrinth now. So we already took care
- 46:05of the bony labyrinth. Now when we talk
- 46:08membranous labyrinth the membranous
- 46:09labyrinth is a continuous
- 46:13series.
- 46:15It's a continuous
- 46:17series
- 46:19of membranous sacks and ducts.
- 46:27Continued within
- 46:30the bony labyrinth.
- 46:32So a continuous series of membranous
- 46:35sacks and ducts
- 46:37continued within the bony labyrinth
- 46:41and following its contours.
- 46:49Now when we talk about this um
- 46:51membranous labyrinth you'll see this
- 46:53membranous membranous labyrinth is going
- 46:55to be filled with a fluid as well. This
- 46:56fluid here is going to be called
- 46:58endolymph.
- 47:05Endolymph.
- 47:07Now endolymph is going to be chemically
- 47:09similar to
- 47:11potassium-rich
- 47:13intracellular fluid.
- 47:17Similar to
- 47:19potassium-rich intracellular fluid. And
- 47:21now this endolymph this endolymph is
- 47:23going to be found in the interior of the
- 47:25membranous labyrinth.
- 47:28It's found in the interior of the
- 47:31membranous labyrinth.
- 47:33So here what we're going to do is we're
- 47:34going to look at
- 47:38this
- 47:40cochlea we'll go into first.
- 47:44And we'll look at the cochlea first and
- 47:46then we'll jump into equilibrium. So
- 47:47let's look at the cochlea here first.
- 47:49Let's grab this part first and here
- 47:54we can appreciate that cochlea.
- 47:57So here you can see what they're doing
- 48:00in this picture in this image is they're
- 48:01going to do a nice L cut basically to
- 48:04this cochlea. Now here with this cut
- 48:07what this going to allow us to do is
- 48:08it's going to allow us to appreciate
- 48:10basically the coils all the way through.
- 48:12So here what you really have is you have
- 48:15one
- 48:16cochlea
- 48:18you can see here
- 48:20that's continuous
- 48:22all the way through
- 48:26all the way
- 48:30to the end.
- 48:33So here now you can see each of these
- 48:37regions of that cochlea
- 48:40themselves are divided up you can see
- 48:42into three different parts.
- 48:44So inside here you have three parts. You
- 48:46can have one part on the top you can see
- 48:48up here
- 48:49one part in the middle which we see
- 48:51right here and then the third part on
- 48:52the bottom which you would got right
- 48:54there.
- 48:55So let's unwind this cochlea. Let's grab
- 48:59it let's unwind it and then we'll do one
- 49:00cut right through. We're going to do one
- 49:02cut right through this is what you're
- 49:03going to have.
- 49:06Coming back so let's unwind this snail
- 49:10looking structure. You completely unwind
- 49:12it pull it all the way open.
- 49:14Okay? So if you were to pull it all the
- 49:16way open this is what we're going to
- 49:17have.
- 49:18You're going to have something that's
- 49:19going to look now like this.
- 49:26Does that make sense?
- 49:27Right? That's what you have here. Unwind
- 49:30it this is what we're going to have. And
- 49:31now within it within it
- 49:34Okay? So let's continue here.
- 49:37Pen color, let me switch to blue.
- 49:41Just to depict the membranous labyrinth.
- 49:48You'll have something looking like this.
- 49:53Okay?
- 49:56So, this is going to be segment one.
- 49:59Here is
- 50:01region two.
- 50:03And then down here we have three, right?
- 50:06So, unwinding this
- 50:08in here would be like one, number two,
- 50:10and then number three. So, let's do
- 50:12this. Let's move over here.
- 50:14Here you've got one. Here you got two.
- 50:16Here you have three. So, number one is
- 50:18known as the scala vestibuli.
- 50:20Scala vestibuli, in the middle you got
- 50:22scala media.
- 50:25And then here on the bottom, scala
- 50:26tympani.
- 50:29Scala tympani.
- 50:31Now, scala media is important because we
- 50:32can see here is where we're going to
- 50:34find the receptor organ for hearing.
- 50:36This is the spiral organ.
- 50:38The receptor organ for hearing.
- 50:40So, moving back
- 50:42this is our image.
- 50:44That spiral organ receptor hearing is
- 50:46all
- 50:48right in here.
- 50:51You basically like you can think of
- 50:53right in here.
- 50:58All right in here.
- 51:03Okay?
- 51:05So,
- 51:07you can see there, scala vestibuli,
- 51:09scala tympani, in the middle, scala
- 51:11media. And then right here we've got the
- 51:13spiral organ,
- 51:14organ of Corti,
- 51:16the sensitive uh
- 51:18receptor region.
- 51:20So, here on the outside we're going to
- 51:22have fluid, right? The bony labyrinth is
- 51:24what we described here. That's going to
- 51:25have perilymph,
- 51:27and then we said endolymph,
- 51:29and then perilymph. So, you see that
- 51:30same thing being described here.
- 51:32Perilymph,
- 51:33perilymph.
- 51:35In the middle you got endolymph.
- 51:38Now, look at here.
- 51:41These parts are continuous with each
- 51:42other.
- 51:44This is the apex.
- 51:50Right here.
- 51:51Apex.
- 51:53At the apex is found at the helicotrema.
- 51:57Right? This area here is the
- 51:59helicotrema, and this is where you find
- 52:01the apex.
- 52:07So, now here
- 52:08let's continue to add in here. Here we
- 52:10have the round window,
- 52:15covered by membrane. Now, you understand
- 52:16why I said this is a valve.
- 52:18Does that make sense now?
- 52:20The fluid inside is what's going to be
- 52:22jiggling.
- 52:23And what do we say is going to be up
- 52:25here?
- 52:26So, here we're going to have I'm going
- 52:27to draw a little bit weird, but here's
- 52:29the stapes.
- 52:33Right? And then here we have the
- 52:36anvil,
- 52:38incus.
- 52:40Here we have the malleus,
- 52:45tympanic membrane,
- 52:48and then the rest of the ear.
- 52:53Right? And then the lobe and
- 52:56all of that is right out here.
- 52:59So, when we talk sound, sound is
- 53:01vibrations of the air. These vibrations
- 53:04of the air are going to make their way
- 53:05into we said
- 53:08that ear.
- 53:11Eventually helping to get that tympanic
- 53:12membrane moving. When the tympanic
- 53:14membrane vibrates, the tympanic membrane
- 53:16is going to get the malleus to move.
- 53:18Malleus will hit up against the incus,
- 53:20which will hit up against the stapes,
- 53:21which is going to hit up against that
- 53:22oval window,
- 53:23which will then get the fluid inside of
- 53:25here to eventually start moving.
- 53:27You see it's like a domino effect is
- 53:29what we're trying to get.
- 53:31So, now here if we're going to see if
- 53:33sounds are of low intensity, those
- 53:36sounds are going to make their way
- 53:37through. They're going to come all the
- 53:38way through to the apex, and then all
- 53:40the way around.
- 53:42They don't ever stimulate
- 53:44the spiral organ, that's why you don't
- 53:45hear them.
- 53:47But now if we talk sounds of higher
- 53:49intensity, those sounds they're not
- 53:51going to be making their way all the way
- 53:52to the back. They're just going to come
- 53:54right through in here, and when they
- 53:55come in here they're just going to get
- 53:57all of this in here to start vibrating.
- 54:00Now, why do we need all this here to
- 54:01vibrate? Because we're going to see that
- 54:03in a few seconds. Let's move over then
- 54:05to this picture here. So, here you can
- 54:07appreciate the spiral organ. Look at the
- 54:09spiral organ, you got the nerve. You've
- 54:10got these important cells in here, and
- 54:12then some supporting cells there. And
- 54:14look at here, you've got a membrane on
- 54:17top and a membrane on bottom. You've got
- 54:18a tectorial membrane right here on top,
- 54:20and we've got a basilar membrane right
- 54:22down here. So, you can see here that
- 54:24spiral organ is sandwiched in between
- 54:26those two membranes.
- 54:28So, let's zoom in on that then.
- 54:31This is what you see.
- 54:33You got your tectorial membrane,
- 54:35and then down here you got the basilar
- 54:36membrane.
- 54:38So, here you can see sandwiched in
- 54:40between them is two rows of cells.
- 54:42You've got
- 54:43one
- 54:45row of inner hair cells and three rows
- 54:47of outer hair cells.
- 54:49So, here what happens now is when sound
- 54:53comes in, now you can see here to each
- 54:55of these hair cells you've got hair
- 54:56bundles. Those hair bundles are embedded
- 54:58within the tectorial membrane.
- 55:01So, here what happens is now when sound
- 55:04comes in
- 55:05So, when sound comes in, sound is going
- 55:07to come in we said it's going to go
- 55:08right through here. It's going to get
- 55:09that basilar membrane vibrating. Now,
- 55:12when that basilar membrane starts to
- 55:13move, here you'll see it's going to get
- 55:16these cells' hairs to bend. And when
- 55:19those hairs bend, this will start to
- 55:23generate signals in the nerves, and
- 55:25letting then the ear know this is what's
- 55:27going on.
- 55:30So, that's how
- 55:33hearing is done.
- 55:36Next then let's talk equilibrium. So, we
- 55:39make sure I've got everything with that
- 55:40cochlea.
- 55:41Coachella. One way you guys like to
- 55:43remember that. Hear sound, Coachella,
- 55:46cochlea.
- 55:48So, yeah. We've got everything there.
- 55:51Let's talk then equilibrium.
- 55:55So, we talk equilibria then
- 55:57let's talk
- 56:00So, this is basically everything we just
- 56:02went through. You can kind of go through
- 56:03that.
- 56:05Okay. Talking about the bending of the
- 56:07stereocilia, how it's going to open up
- 56:10ion channels, helping to trigger
- 56:13electrical signals.
- 56:23And then again the pathway you can
- 56:24appreciate there as well.
- 56:27Let's talk then equilibrium. So,
- 56:30equilibrium then we'll see is going to
- 56:31be a sense
- 56:33that not only depends on input from the
- 56:35internal ear. So, it's a sense that's
- 56:37not only going to depend on input from
- 56:38the internal ear, but also it's going to
- 56:40depend on information from vision,
- 56:44and it's going to depend on information
- 56:45coming from stretch receptors
- 56:50in relation to our muscles and our
- 56:51tendons.
- 56:54And also from our stretch receptors in
- 56:56relation to our muscles and tendons.
- 56:59Now, here we have first
- 57:02our maculae. Our maculae are described
- 57:05as sensory receptors for static
- 57:08equilibrium.
- 57:09Sensory receptors for static
- 57:11equilibrium. When you talk about their
- 57:13function, their function is that they
- 57:15monitor the position of the head in
- 57:17space.
- 57:19They will monitor the position of the
- 57:20head in space.
- 57:22They also play a key role in posture.
- 57:29Where are they found? They're going to
- 57:30be found as we described, one
- 57:33in each saccule
- 57:36and utricle wall.
- 57:41One in each saccule and utricle wall.
- 57:48Utricle.
- 57:54Now here when you look at the position,
- 57:55you can see how each of them are going
- 57:57to be found. One is
- 57:59vertically placed, one is a little bit
- 58:01more horizontally placed.
- 58:03So, here now what happens is like we
- 58:04described, they're going to monitor the
- 58:07position of the head in space.
- 58:09But not only the monitor not only
- 58:10monitoring position of the head in
- 58:11space,
- 58:13also linear acceleration
- 58:15we'll see there as well.
- 58:18Linear acceleration, let's say you're
- 58:19standing here and all of a sudden you
- 58:20start to move forward fast.
- 58:22Right? This is linear acceleration. Even
- 58:24elevators, right? Moving up and down in
- 58:26elevator. Okay, vertical acceleration
- 58:29you've got happening there, but that's
- 58:30not that common. More is this
- 58:32uh
- 58:33you can see this linear acceleration.
- 58:37Next then here when we go through and we
- 58:38talk uh
- 58:39maculae, now what happens here when we
- 58:41look at their structure, you can see
- 58:42here in greater detail the maculae are
- 58:45made up of also supporting cells and
- 58:47hair cells. Now, these hair cells have
- 58:49these hair bundles. Those hair bundles
- 58:52have you'll see now a whole bunch of
- 58:55stereocilia
- 58:57and
- 58:58a kinocilium.
- 59:01Stereocilia and a kinocilium. So, that
- 59:04makes up a hair bundle. Those hair
- 59:05bundles themselves now are embedded
- 59:08within this otolithic membrane, this
- 59:11rocky membrane you see there. Otolithic,
- 59:15rocky membrane. So, you can see that
- 59:16membrane is going to cover all of those
- 59:19hair bundles. So, here now what happens
- 59:22is as soon as you have the position of
- 59:24the head start to change, what this does
- 59:27it's going to get those stereocilia
- 59:30and the kinocilium to start to bend. It
- 59:32gets those hair bundles to bend. So,
- 59:34when those hair bundles start to bend,
- 59:36now depending on whether they're bending
- 59:38towards or away from the kinocilium,
- 59:41this will trigger then
- 59:43action potentials or signals along these
- 59:45nerves, letting then the brain know
- 59:47what's going on.
- 59:52So, you can see exactly that happening.
- 59:53Here, this individual goes from the
- 59:55seated position to where they put their
- 59:57head down a bit, and this gets this
- 59:59otolithic membrane membrane to start
- 1:00:01moving.
- 1:00:04Next then, we have our cristae
- 1:00:06ampullaris.
- 1:00:08Now, the cristae ampullaris are going to
- 1:00:10be receptors for dynamic equilibrium.
- 1:00:13Receptors for dynamic equilibrium.
- 1:00:16Their function is that they get
- 1:00:18stimulated by head movements. Now, they
- 1:00:21get stimulated by head movements, but in
- 1:00:23this case, you'll see the majority the
- 1:00:26major stimulus are going to be rotary or
- 1:00:29angular head movements. Rotary or
- 1:00:32angular head movements.
- 1:00:36Where are these receptors found? These
- 1:00:38receptors are going to be found
- 1:00:40in the ampulla of each semicircular
- 1:00:42canal as we described.
- 1:00:44In the ampulla of each semicircular
- 1:00:45canal.
- 1:00:47Now, here what we have is we'll move
- 1:00:49over to this picture. Here what we have
- 1:00:50is you can appreciate now
- 1:00:53hair cells again, hair bundles. Okay?
- 1:00:56Again, supporting cells there as well.
- 1:00:58Now, here you have a cupula on top. Here
- 1:01:00you have a cupula
- 1:01:03enclosing all those hair bundles. So,
- 1:01:05now here what happens is you can see
- 1:01:08when we have these rotary movements.
- 1:01:11Okay? These rotary movements are going
- 1:01:13to cause this endolymph
- 1:01:17to start to turn in the opposite
- 1:01:19direction.
- 1:01:20So, here what happens is you can see
- 1:01:22now, if we're going to be moving in one
- 1:01:24direction, this fluid is going to be
- 1:01:26moving in the opposite direction. And
- 1:01:28what that does, it gets basically this
- 1:01:29cupula to start to bend, and that's
- 1:01:31going to get those, again, same concept,
- 1:01:34hair cells,
- 1:01:36their bundles, the hair bundles, to
- 1:01:37bend, and that's going to start then
- 1:01:39sending signals to the brain, letting
- 1:01:41the brain know, "Hey, we've got these
- 1:01:43rotary movements occurring."
- 1:01:47So, that there then is equilibrium as
- 1:01:49well.
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