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AnatomyRespiratory — Transcript

by Dr. Naveen Jalota, M.D. · 9,452 words · 1,382 segments · language en · Watch on YouTube

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  1. 0:00hello and welcome let's start talking
  2. 0:03about let's start by talking about the
  3. 0:06respiratory system so here now when we
  4. 0:08go through and we talked about the
  5. 0:10respiratory system again we'll go
  6. 0:11through first and we'll talk about all
  7. 0:12the different components there as well
  8. 0:15and then we'll go through each
  9. 0:16individual component like we did with
  10. 0:18gastrointestinal system so here first
  11. 0:20what we'll do is I'll introduce you to
  12. 0:23the components that make up this
  13. 0:24respiratory system and I'm gonna go
  14. 0:26through the basic functions and then
  15. 0:27we'll go through and hit each every each
  16. 0:29and every one of those different
  17. 0:31basically parts so here now when we go
  18. 0:34through you can see this is making up
  19. 0:36basically the respiratory system now we
  20. 0:38can see here the majority of it and
  21. 0:41there are some parts that we're not able
  22. 0:43to see that we're going to see why us
  23. 0:45zooming in on to the lungs and looking
  24. 0:47at them then in greater detail so first
  25. 0:50here let's see we could see when we talk
  26. 0:52respiratory system first we've got what
  27. 0:54we call the nose the nasal cavity will
  28. 1:02see our paranasal sinuses that we have
  29. 1:05already looked at and we've talked about
  30. 1:07in relation to all the various bones
  31. 1:10we've seen right around this nasal
  32. 1:13cavity your pharynx aka your throat your
  33. 1:21pharynx next in here we've got our
  34. 1:23larynx larynx and then we've got the
  35. 1:29trachea the trachea or windpipe aka
  36. 1:34right and then you can see here it
  37. 1:37divides the trachea divides it divides
  38. 1:39into our bronchi and then more
  39. 1:41specifically speaking you can see you
  40. 1:44can have right and left main bronchi or
  41. 1:46primary bronchi so that's what we're
  42. 1:50seeing here and then they're going to
  43. 1:52subdivide even further and further as
  44. 1:56they move deeper into the lungs kind of
  45. 1:59like arteries do so when we move there
  46. 2:04we'll see then the main bronchi plus
  47. 2:06they're successively smaller branches
  48. 2:09all the way to the level of the alveoli
  49. 2:14that are inside the lungs and then we'll
  50. 2:16look at all of that stuff when we move
  51. 2:18down to the inside of the lungs so all
  52. 2:23the various parts of the respiratory
  53. 2:25system now let's go through the basic
  54. 2:27functions here so we go through
  55. 2:28functions a main function we have here
  56. 2:31is gas exchange to supply the body with
  57. 2:35oxygen and rid the body of carbon
  58. 2:39dioxide remove co2 dispose of co2 now
  59. 2:44between the blood you can see an air so
  60. 2:47know how does all of this happen this is
  61. 2:50going to happen thanks to four processes
  62. 2:55that are going to collectively be called
  63. 2:59respiration now we'll go through we'll
  64. 3:04look at these four processes in a few
  65. 3:05seconds before we do that let me go to
  66. 3:07the rest of the functions here speech
  67. 3:09and other vocalization Oh faction the
  68. 3:15sense of smell right we've gone through
  69. 3:16we've talked about we've seen where that
  70. 3:18was also the respiratory system is going
  71. 3:21to help control the pH of the body the
  72. 3:23body's pH it'll work with will see our
  73. 3:26kidneys it aids in regulation of blood
  74. 3:32pressure by assisting angiotensin ii
  75. 3:36production if you recall our Roth system
  76. 3:40helps create pressure gradients for the
  77. 3:43flow of lymph and venous blood also it's
  78. 3:49involved with the expulsion of abdominal
  79. 3:51contents with defecation and we have the
  80. 3:56valsalva maneuver where you'll close the
  81. 4:01glottis applying pressure basically in
  82. 4:04that abdominal cavity so all various
  83. 4:09functions of the respiratory system
  84. 4:10let's focus in here on the first
  85. 4:12function this is what we're going to be
  86. 4:15really concerned with that's gas
  87. 4:16exchange right we talked about we'll
  88. 4:19talk to other vocalization in speech
  89. 4:21when we get to the vocal cords smell
  90. 4:23we've already checked out we've looked
  91. 4:24at pH control you'll see that in physio
  92. 4:27here we saw with endocrine okay this
  93. 4:31we're going to see with cardiovascular
  94. 4:33and in this here we saw now as we
  95. 4:36mentioned so let's talk then respiration
  96. 4:40let's talk four processes that we refer
  97. 4:41to as respiration now here these four
  98. 4:44processes that we refer to as
  99. 4:46respiration are going to be known as
  100. 4:48pulmonary ventilation number one
  101. 4:51pulmonary ventilation will see as number
  102. 4:54one when we talk pulmonary ventilation
  103. 4:57pulmonary ventilation is basically
  104. 5:00breathing so what I'll do is all right
  105. 5:01that appear as number one and then we'll
  106. 5:05write P and a V for pulmonary
  107. 5:09ventilation or breathing now when we
  108. 5:13talk pulmonary ventilation or breathing
  109. 5:15this is exactly what its name says
  110. 5:18pulmonary ventilation or like we said
  111. 5:20breathing this process okay this is one
  112. 5:24of the four processes that are going to
  113. 5:26cook are going to be basically making up
  114. 5:30what we call we said respiration where
  115. 5:32this is going to help with gas exchange
  116. 5:35so we'll see if one of these four
  117. 5:37processes aren't working doing their job
  118. 5:40basically then gas exchange respiration
  119. 5:43is not going to be occurring properly
  120. 5:45there either
  121. 5:46okay so first pulmonary ventilation
  122. 5:48pulmonary ventilation is the process of
  123. 5:49breathing you know like we said it's
  124. 5:51talking about the process of moving
  125. 5:53oxygen right in to and co2 out of oxygen
  126. 6:06into the lungs and co2 out of the lungs
  127. 6:15so again for you to be able to exchange
  128. 6:17gas you have to be able to get air into
  129. 6:21and out of the lungs so you have to be
  130. 6:24able to get air into and out of the
  131. 6:25lungs and we get more specific basically
  132. 6:27getting oxygen into and co2 out of the
  133. 6:30lungs right if we have this process
  134. 6:34let's say traumatic accident where you
  135. 6:38know a patient has
  136. 6:39something on top of their chest and you
  137. 6:42hear this a lot even I work on cars I
  138. 6:45like working on cars so I hear this a
  139. 6:47lot with mechanics give the car not
  140. 6:51being properly stabilized and it leading
  141. 6:55to a traumatic accident where now it's
  142. 6:58on the individual nobody is there or
  143. 7:01this individual is unable to get this
  144. 7:03vehicle off and now this pulmonary
  145. 7:05ventilation step is going to not be
  146. 7:07occurring so then gas exchange is not
  147. 7:10going to be occurring okay so you see
  148. 7:12how this is all part of a big picture so
  149. 7:14first you have pulmonary ventilation
  150. 7:15right so you have to be able to refresh
  151. 7:17these gases refresh this air next then
  152. 7:21we're going to talk about external
  153. 7:24respiration external respiration when we
  154. 7:27talk about external respiration the
  155. 7:29second process external respiration is
  156. 7:31talking about the movement of oxygen now
  157. 7:34from the lungs from the lungs into the
  158. 7:37blood let's just draw a blood vessel
  159. 7:40right here next to the lungs
  160. 7:45okay so here we're going to see in the
  161. 7:49next region this is actually your
  162. 7:50pulmonary circulation so here we can see
  163. 7:54now we've got air in right so oxygen
  164. 7:57made its way all the way down into the
  165. 8:00lungs okay so oxygen made its way all
  166. 8:07the way down right and co2 is what then
  167. 8:10made its way out is what we're looking
  168. 8:12at here okay so now we've got this
  169. 8:14oxygen inside the lungs now the second
  170. 8:17step okay the second step I'm talking
  171. 8:20about here external respiration okay
  172. 8:25external respiration you can see now is
  173. 8:29dealing with the movement of this oxygen
  174. 8:32from the lungs and into the blood vessel
  175. 8:35we have to be able to move that oxygen
  176. 8:38into the blood vessels and again
  177. 8:41vice-versa for co2 always think opposite
  178. 8:43for co2 now if this doesn't occur right
  179. 8:47gas exchange is it occurring again going
  180. 8:49back to the function so this here you
  181. 8:52can see is step
  182. 8:53to the number three is dealing with the
  183. 8:57transport we have to be able to move
  184. 9:00this gas now this oxygen to its proper
  185. 9:05place now this oxygen we're talking
  186. 9:07about moving to organs and tissues and
  187. 9:10cells so I'll just draw a little cell
  188. 9:12here just to kind of give you that idea
  189. 9:14and here you can see you've got a little
  190. 9:16epithelial cell okay so it's making up
  191. 9:19you know tissue is the big picture we
  192. 9:21want to get here so make this nucleus a
  193. 9:24little bit more circular alright so now
  194. 9:29we have to be able to move transport
  195. 9:32this gas right oxygen to the tissue
  196. 9:37cells and co2 vice-versa
  197. 9:40so this now is step three now step three
  198. 9:45is transport of gases so transport of
  199. 9:50respiratory gases now involves which
  200. 9:53system you can see now we've got
  201. 9:56cardiovascular system coming in so
  202. 9:58without the cardiovascular system these
  203. 10:00last two steps would not be able to
  204. 10:02occur now fibrosis is one problem that
  205. 10:07can occur here let's say an occlusion is
  206. 10:10another problem that can occur here now
  207. 10:12let's see and now step 4 step 4 is going
  208. 10:15to be internal respiration internal
  209. 10:20respiration now when we talk internal
  210. 10:23respiration internal respiration is
  211. 10:25going to deal with now the movement of
  212. 10:27these gases from that circulatory system
  213. 10:31from the blood vessels now from the
  214. 10:35blood the blood vessels to the tissues
  215. 10:38cells to the tissues cells so that
  216. 10:42oxygen now actually moving into the
  217. 10:44tissue cells and opposite up co2 as
  218. 10:49we've described so here you can see now
  219. 10:51this is internal respiration now these
  220. 10:54four steps these four processes
  221. 10:56collectively okay so we'll say here
  222. 11:00these four processes collectively make
  223. 11:06up what
  224. 11:07we referred to them as respiration and
  225. 11:21that is how gases will be exchanged at a
  226. 11:27basic level right at a basic level next
  227. 11:34time let's move down let's go through
  228. 11:36all of these different structures here
  229. 11:40now and let's actually classify them
  230. 11:42into two categories okay so let's do
  231. 11:46this let's look at then let's go back
  232. 11:50here
  233. 11:51so first way to divide these components
  234. 11:55you can see is a conduction it is going
  235. 11:58to be through this conducting division
  236. 11:59and respiratory division and also
  237. 12:01through an upper respiratory tract and a
  238. 12:04lower respiratory tract so let's do this
  239. 12:05division here first and then we'll jump
  240. 12:07into this division here in greater
  241. 12:09detail so here when we go through we
  242. 12:11talk upper respiratory tract nose
  243. 12:13through larynx lower respiratory tract
  244. 12:17then trachea down to the lungs trachea
  245. 12:22okay trachea through the lungs lower
  246. 12:25respiratory tract upper nose through
  247. 12:30larynx that's upper respiratory tract
  248. 12:34hiepro you're familiar with upper
  249. 12:36respiratory tract infection lower
  250. 12:37respiratory tract infection okay so this
  251. 12:39is where we're relating that to okay so
  252. 12:42that's what they're talking about
  253. 12:43they're talking about those specific
  254. 12:45regions or specific areas so let's
  255. 12:48divide everything up into zones
  256. 12:50conducting zone and respiratory zone so
  257. 12:52here first I want to talk to you about
  258. 12:54your respiratory zone now when we talk
  259. 12:56respiratory's own respiratory zone I
  260. 12:58want you to know first is your actual
  261. 13:01site of gas exchange it's the actual
  262. 13:04site of gas exchange it is composed of
  263. 13:09your respiratory bronchials your
  264. 13:15alveolar ducts
  265. 13:19and your alveoli these are all your
  266. 13:23microscopic structures so let's zoom in
  267. 13:26basically in here and let's look at all
  268. 13:29of those structures so let's move all
  269. 13:32the way to right inside of here now so
  270. 13:37first you can see the branching pattern
  271. 13:40through the lungs so I told you these
  272. 13:43primary bronchi are going to make their
  273. 13:45way deeper into the lungs and as they
  274. 13:46make their way deeper than lungs I told
  275. 13:48you they're going to give off
  276. 13:49successively smaller branches right so
  277. 13:51that's what you see we refer to this
  278. 13:53branching pattern as the bronchial tree
  279. 13:57branching pattern okay it looks like a
  280. 14:00tree and fall okay basically no leaves
  281. 14:04it's all the branches that you see there
  282. 14:05so here now you can see as we make our
  283. 14:09way all the way in so this is going all
  284. 14:10the way through okay this is the alveoli
  285. 14:13the ending basically so here now when we
  286. 14:17talk respiratory zone it's I told you
  287. 14:20the actual site of gas exchange so it's
  288. 14:22going to be made up of what we call the
  289. 14:26respiratory bronchioles so you can see
  290. 14:28coming all the way into here and making
  291. 14:32our way all the way right before the
  292. 14:35alveolar cluster you can see is the
  293. 14:39respiratory bronchial
  294. 14:40that's where then the respiratory zone
  295. 14:42will begin look at this picture here you
  296. 14:45can see coming all the way into the
  297. 14:47lungs making our way all the way towards
  298. 14:48the ending okay so we zoom in on this
  299. 14:51area here and we zoom in on that area
  300. 14:53here there's the same picture that we
  301. 14:54just saw you can see you got your
  302. 14:56terminal bronchioles then here you can
  303. 14:58see the respiratory bronchioles so it's
  304. 15:01composed of the respiratory bronchioles
  305. 15:03we said then the alveolar ducts right
  306. 15:06the ducts leading to the alveoli and
  307. 15:08then the alveoli themselves all
  308. 15:11microscopic structures that's why you
  309. 15:14can see here we've had to zoom in on
  310. 15:15these structures to be able to
  311. 15:17appreciate them so this is your
  312. 15:21respiratory zone from here down to the
  313. 15:26alveoli and if we
  314. 15:29from here okay from the terminal
  315. 15:31bronchioles if we go from these terminal
  316. 15:34bronchioles and we go basically all the
  317. 15:36way up and we go all the way up okay so
  318. 15:40if you go from the terminal bronchioles
  319. 15:42you got these bronchioles and we go all
  320. 15:44the way up back up into here all the way
  321. 15:49up into the trachea the larynx okay all
  322. 15:54the way back up into here now all of
  323. 15:57these structures now make up what we
  324. 15:59call the conducting zone what are they
  325. 16:02doing very good they're conducting this
  326. 16:06here they're conducting this air through
  327. 16:10two of the alveoli and away from the
  328. 16:14alveoli so these are what we call your
  329. 16:17conducting zone structures so we talk
  330. 16:20conducting zoning it includes all other
  331. 16:22respiratory passageways apart from what
  332. 16:26we saw those respiratory bronchioles the
  333. 16:29ducts of the alveoli and the alveoli
  334. 16:32themselves now what do these conducting
  335. 16:37zone structures do besides conduct air
  336. 16:40they're also going to they're also going
  337. 16:45to be responsible for cleaning
  338. 16:49humidifying warming and creating
  339. 16:55turbulence in this air which is going to
  340. 17:00be involved with again helping to clean
  341. 17:02and humidify and also warm this incoming
  342. 17:06air so by the time it reaches the
  343. 17:11alveoli the temperature has changed and
  344. 17:15it's cleaned and then we said the
  345. 17:19respiratory zone is the actual site of
  346. 17:22gas exchange you make sense so let's go
  347. 17:29through the various organs let's start
  348. 17:31with the nose first now when we talk
  349. 17:32about the nose the nose is the only
  350. 17:35externally visible part of this
  351. 17:39respiratory system everything else is
  352. 17:41hidden inside you don't see it
  353. 17:43pretty cool no we both are we talk about
  354. 17:45the knows the function of the nose
  355. 17:47number one it provides an airway for
  356. 17:49respiration number two it's going to
  357. 17:53moisten and warm this entering the air
  358. 18:00number three it filters and cleans
  359. 18:05inspired air number four it serves as a
  360. 18:12resonating chamber for speech number
  361. 18:18five
  362. 18:19it houses the olfactory or your smell
  363. 18:25receptors now when we talk about the
  364. 18:30structures in relation to the nose you
  365. 18:34can see the nose is going to be divided
  366. 18:36in two it's an external nose and an
  367. 18:40internal nasal cavity we erase all this
  368. 18:47so if you divided up into an external
  369. 18:50nose and an external nose and an
  370. 18:54internal nasal cavity so you could see
  371. 19:04that there then as two separate
  372. 19:10divisions in so here now let's focus in
  373. 19:15on this region in greater detail so we
  374. 19:17focus in on this region there that in
  375. 19:19greater detail here we could see first
  376. 19:21the external nose so let's go through
  377. 19:24the external nose and then we'll check
  378. 19:26out the internal notes now when we talk
  379. 19:28about this external nose the external
  380. 19:29nose you can see is made up of a few
  381. 19:31parts and we'll go through these few
  382. 19:33parts here you can see number one this
  383. 19:35external nose is found located between
  384. 19:37the orbits and then also superior to
  385. 19:40that oral cavity now here you can see
  386. 19:44first we have what we call the root of
  387. 19:47the nose is where the nose you can see
  388. 19:51is going to begin this is where then you
  389. 19:53can see those nasal bones
  390. 19:56are going to be found right articulating
  391. 20:00with the rest of these bones here here
  392. 20:05you can see in greater detail then those
  393. 20:09two nasal bones frontal bone if you
  394. 20:13recall then we had our maxillary bones
  395. 20:17right and then here we have cartilage
  396. 20:24are they telling us okay very good which
  397. 20:27cartilage which cartilage do we see out
  398. 20:31here making up that nose right is it
  399. 20:34fibrocartilage know is it elastic
  400. 20:39elastic was easy right because it's only
  401. 20:41found in its elastic it's easy because
  402. 20:45it's only found in the epiglottis and
  403. 20:48the ear that you have to know if at 40 s
  404. 20:50so nope no last one left so here then
  405. 20:56when we go through then we go through
  406. 20:57and you can see that those two nasal
  407. 20:59bones so the root we're going to see
  408. 21:02where that nose is going to begin at we
  409. 21:05refer to that then here we're going to
  410. 21:06see the bridge so this leads us to the
  411. 21:08bridge then here you can see you've got
  412. 21:11the bridge so the bridge in the root are
  413. 21:14found between the eyebrows and the
  414. 21:18orbits the orbital cavities the bridge
  415. 21:24then will lead us to the dorsum nasai
  416. 21:26the dorsum NASA this is that you can
  417. 21:28think of the arch the arch of the nose
  418. 21:32which will then lead us to the apex the
  419. 21:36apex or the terminal part the tip of the
  420. 21:38nose and then from the tip of the nose
  421. 21:41we can see if we flare laterally then we
  422. 21:45encounter the LA the wings at the wing
  423. 21:48like parts the LA and they're going to
  424. 21:54help form the nostrils
  425. 21:56they will help form daenerys the
  426. 21:59nostrils so when we talk then the nasal
  427. 22:03cavity the nasal cavity is internal it's
  428. 22:07found lying
  429. 22:09in and posterior to this external nose
  430. 22:16we've got first then veneers
  431. 22:19they're gonna allow air to pass into the
  432. 22:22nasal cavity the nostrils right next we
  433. 22:26have the nasal septum it divides the
  434. 22:28nasal cavity into equal right and left
  435. 22:30halves and you should be able to recall
  436. 22:33the bones that we have there and in the
  437. 22:37parts of the bones as well specifically
  438. 22:39speaking so let's look at the inside now
  439. 22:42when we look at the inside you got this
  440. 22:44view here in this view here okay some
  441. 22:47nice views let's zoom in on this views
  442. 22:49basically what we're doing here so here
  443. 22:51we could appreciate now the posterior
  444. 22:54nasal aperture the posterior nasal
  445. 22:58aperture is found you can see right
  446. 23:02inside of here this posterior nasal
  447. 23:06aperture is basically you could think of
  448. 23:09the archway and it allows this nasal
  449. 23:12cavity to be continuous with the nasal
  450. 23:16pharynx it allows the nasal cavity to be
  451. 23:23continuous with the nasal portion of the
  452. 23:26pharynx or more specifically speaking
  453. 23:29the nasal pharynx next then we're able
  454. 23:34to appreciate here the roof and the
  455. 23:36floor of the nasal cavity the roof of
  456. 23:40the nasal cavity is formed by the
  457. 23:44ethmoid bone and the sphenoid bones of
  458. 23:49the skull you can see that here very
  459. 23:53clearly now when we talk about the floor
  460. 23:57the floor of this nasal cavity is formed
  461. 24:01by the palate the palate we had two
  462. 24:06divisions hard and soft right so I'm
  463. 24:09just saying palate because both are
  464. 24:11involved here no here you can see first
  465. 24:13we have the hard palate and then here we
  466. 24:17can appreciate the soft palate which led
  467. 24:20us to the uvula the pendulous structure
  468. 24:23we saw at the dorsal aspect of that oral
  469. 24:26cavity and then the two here helped to
  470. 24:29close off that entrance into the nasal
  471. 24:31pharynx when we swallowed right we
  472. 24:32discussed all that when we talked about
  473. 24:34gastrointestinal system GI tract so you
  474. 24:40can see why then cleft lip cleft palate
  475. 24:45can become problematic for the patient
  476. 24:48and we have to go in surgically and help
  477. 24:51repair this next then we have the nasal
  478. 24:56vestibule so I want you to make sure you
  479. 24:58understand the cleft lip palate
  480. 25:00now your hundred-percent gear have to
  481. 25:02know everything about that we've talked
  482. 25:03about the bones and we've talked about
  483. 25:05this now and rinsing this condition
  484. 25:08second time now so nasal vestibule then
  485. 25:12we talk nasal vestibule the nasal
  486. 25:14vestibule vestibule we've used this term
  487. 25:16now a few times vestibule you can see
  488. 25:19now is a part of the nasal cavity that's
  489. 25:22found just superior to the nostrils it's
  490. 25:25the part of the nasal cavity just
  491. 25:27superior to the nostrils the nasal
  492. 25:30vestibule
  493. 25:31so the recess is a space you could think
  494. 25:33of found just superior to the nostrils
  495. 25:37it's lined with skin that's going to
  496. 25:41contain sebaceous glands sweat glands
  497. 25:47and numerous hair follicles those hair
  498. 25:54follicles will contain the Vibrio say
  499. 25:57the hairs those Vibrio say the hairs
  500. 26:00what they're going to do is they're
  501. 26:01going to they're going to filter horse
  502. 26:04particles from this inspired air they
  503. 26:08will filter very coarse particles from
  504. 26:12this inspired air you also have inside
  505. 26:19of here olfactory mucosa besides that
  506. 26:27I'm so you also have olfactory
  507. 26:29epithelium factory because you're gonna
  508. 26:31find her up inside of here besides we'll
  509. 26:34see basically nasal
  510. 26:36Koza so we're gonna have a couple of
  511. 26:38different types of miko say inside of
  512. 26:39here so first let's talk olfactory
  513. 26:41mucosa olfactory mucosa
  514. 26:44we've talked a little bit about before
  515. 26:45okay it's the olfactory because there's
  516. 26:48gonna be mucous membrane it lines the
  517. 26:50slit like superior region of the nasal
  518. 26:55cavities right specifically speaking we
  519. 26:57said it's found on the superior nasal
  520. 26:59conchae so you could see those right
  521. 27:02inside of here now again and this whole
  522. 27:07factory mucosa is going to contain your
  523. 27:09smell receptors the main component we
  524. 27:11had there also inside of here is going
  525. 27:15to be then respiratory mucosa refer to
  526. 27:18it as respiratory mucosa now respiratory
  527. 27:21mucosa is going to be made up of pseudo
  528. 27:24stratified ciliated columnar epithelium
  529. 27:28pseudo stratified ciliated columnar
  530. 27:31epithelium it will contain scattered
  531. 27:36goblet cells that are going to rest on
  532. 27:42lamina propia
  533. 27:46that is richly supplied with mucous and
  534. 27:52serous glands which produced then mucous
  535. 28:00and watery fluid that's gonna contain
  536. 28:03enzymes within this nasal cavity we also
  537. 28:12have lots of sensory nerve endings so
  538. 28:17that nasal mucosa is richly supplied
  539. 28:21with sensory nerve endings when they
  540. 28:25come into contact with irritants this
  541. 28:29triggers the sneeze reflex so when they
  542. 28:33come into contact with irritants this
  543. 28:35trigger is the sneeze reflex and
  544. 28:38sneezing it forces air outward it forces
  545. 28:44air outward in a violent burst and
  546. 28:48that's a way
  547. 28:50of expelling those irritants from this
  548. 28:53pathway also within this cavity are
  549. 29:00going to be capillary plexuses capillary
  550. 29:04plexus are gonna be found in abundant
  551. 29:06quantities and they underlie the nasal
  552. 29:10epithelium what they're responsible for
  553. 29:14doing is they're responsible for warming
  554. 29:16this incoming air unfortunately
  555. 29:21sometimes putting our introducing our
  556. 29:26finger into the nasal cavity and
  557. 29:29reducing the digit into the nasal cavity
  558. 29:31and irritating the mucosa can lead to
  559. 29:35nosebleeds or even naughty of putting
  560. 29:42your finger inside your irritating
  561. 29:44scratching like this or you know doing
  562. 29:46other things there can also lead to
  563. 29:48these capillary plexuses bursting and
  564. 29:50you having what we call it these taxes
  565. 29:52they're bloody nose so nasal conchae you
  566. 29:59can see there's three we've spoken of
  567. 30:01them before now they're scroll like
  568. 30:05mucosa covered projections I've
  569. 30:07described them to you as and you can see
  570. 30:10they protrude medially from each lateral
  571. 30:13wall of the nasal cavity and they
  572. 30:17increase the mucosal surface area they
  573. 30:22enhance air turbulence in that cavity
  574. 30:28also again you have three of them one
  575. 30:33two three or they're better known as the
  576. 30:36superior nasal Concha middle nasal
  577. 30:39Concha and inferior nasal Concha and
  578. 30:42then right beneath each of them you can
  579. 30:45appreciate the meatus is the groove
  580. 30:50right that air is going to make its way
  581. 30:54through as it passes
  582. 30:59so grooves inferior to each of the
  583. 31:01conchae the missus man then paranasal
  584. 31:06sinuses we've talked about and we've
  585. 31:09talked about the paranasal sinuses and
  586. 31:10we've discussed about how they're going
  587. 31:13to be found we've seen them to be found
  588. 31:15in relation to the nasal cavity so make
  589. 31:19sure you review review those and go
  590. 31:21through those and check those out then
  591. 31:23as well so they surround the nasal
  592. 31:26cavity located in the frontal sphenoid
  593. 31:28ethmoid maxillary bones not only do they
  594. 31:31lighten the skull together with the
  595. 31:34cavities they're going to warm and moist
  596. 31:36in here let's move that into the pharynx
  597. 31:43let's move into the pharynx the throat
  598. 31:46area so let's zoom in on this area here
  599. 31:48and here you can see that post your
  600. 31:51knees aperture from this view you really
  601. 31:52can't appreciate it as well as you can
  602. 31:54appreciate it right in here you can see
  603. 31:56the archway much better right inside of
  604. 31:58here
  605. 32:03so let's zoom in on them basically this
  606. 32:07area here we've got now the pharynx your
  607. 32:09throat right we referred to it as we
  608. 32:12said it's a funnel-shaped now I want you
  609. 32:15to know this pharynx is going to extend
  610. 32:17it extends about five inches from the
  611. 32:23base of the skull to the level of c6 to
  612. 32:32the level of c6 so one two three four
  613. 32:36five six level of c6 we could see there
  614. 32:41now the functions of this pharynx okay
  615. 32:44so let's zoom in on this picture let's
  616. 32:47move to this picture you can see all the
  617. 32:52way through when we talk about the
  618. 32:55pharynx its function is that it contains
  619. 32:58I'm sorry it's gonna connect it'll
  620. 33:00connect the nasal cavity it'll connect
  621. 33:06the nasal cavity down too you can see
  622. 33:10this oral pharynx it'll connect this
  623. 33:13oral cavity also down to the sorrel
  624. 33:15pharynx the nasal cavity connect
  625. 33:17smelling to the laser friends but then
  626. 33:18also down to the oral pharynx you can
  627. 33:19see which then all connect down into the
  628. 33:22laryngopharynx so it connects nasal
  629. 33:27cavity the oral cavity right to the
  630. 33:31larynx and this esophagus inferiorly
  631. 33:38from these two superior locations so
  632. 33:43larynx we're gonna look at in greater
  633. 33:44detail esophagus you're going to have
  634. 33:47back here so it connects these two
  635. 33:52cavities down to these two cavities
  636. 33:55basically all your throat or your
  637. 34:01pharynx if you're speaking again in
  638. 34:04medical terms so let's go through the
  639. 34:07nasal pharynx first cuz we've already
  640. 34:09talked about the oral we've already
  641. 34:10talked about the low angle right so
  642. 34:11let's talk nasal pharynx when top nasal
  643. 34:15pharynx posterior to the nasal cavity
  644. 34:17inferior to the sphenoid bone which we
  645. 34:21have right up in here and we talked
  646. 34:23about getting to the pituitary gland I
  647. 34:24told you we're gonna make our way to
  648. 34:26right through this cavity right inside
  649. 34:29of here no need to make your way up
  650. 34:31through here and go we'll try to come
  651. 34:33underneath here right through here so
  652. 34:39inferior to the sphenoid bone and
  653. 34:43superior to the level of the soft palate
  654. 34:45and superior to the level of the soft
  655. 34:49palate
  656. 34:51here's your nasal pharynx right again
  657. 34:54you can see that there it's function it
  658. 34:58serves as an air passageway nowadays I
  659. 35:03think some young individuals are
  660. 35:04allowing it to serve as a passageway for
  661. 35:06food items right putting spaghetti in
  662. 35:09here and lots of other things and
  663. 35:11bringing it down the mouth and they're
  664. 35:13doing these little tricks there I guess
  665. 35:15they got tired and bored of eating tied
  666. 35:17pots so they came to this thing and now
  667. 35:19I don't know what the newer generation
  668. 35:21does it's changing every few years I
  669. 35:25hear of you
  670. 35:27update me with the newer trends so here
  671. 35:31maybe somebody will email me and let me
  672. 35:32know what the new trend is now right
  673. 35:34went from Tide Pods to I don't know
  674. 35:39inhaling snorting condoms I believe it
  675. 35:42was to then putting food through this
  676. 35:44fairing so you can see the generations
  677. 35:47have changed a bit and their activities
  678. 35:50have changed a bit as we progress every
  679. 35:54generation has their own thing there
  680. 35:56right so now when we cope them to talk
  681. 35:57about the nasopharynx so it serves as an
  682. 36:00air passageway oral and luring go we
  683. 36:04talked about already before because
  684. 36:05we've already talked about digestive
  685. 36:07systems so digestive system digestive
  686. 36:09tract so now we talk nasal Franks nasal
  687. 36:13Franks I'd like you to know is lined
  688. 36:14with pseudo stratified ciliated
  689. 36:15epithelium pseudo stratified ciliated
  690. 36:17epithelium now located inside of here
  691. 36:21are going to be the Ferengi Ilan Souls
  692. 36:22here we can appreciate the Ferengi Oh
  693. 36:24tonsils the fringe of tonsils them
  694. 36:27affected are gonna be known as your
  695. 36:28adenoids your adenoids you can see
  696. 36:32they're located high on the posterior
  697. 36:33wall don't they are located high up on
  698. 36:36the posterior wall and what they do is
  699. 36:39they help trap and destroy pathogens
  700. 36:42they will trap and destroy pathogens
  701. 36:44that are entering the nasal pharynx that
  702. 36:49are going to be entering into the nasal
  703. 36:50pharynx we can also appreciate the
  704. 36:54opening of the fringe or tympanic tube
  705. 36:56that we've already talked about
  706. 36:57now this opening here is going to allow
  707. 37:01us to drain the middle ear as we have
  708. 37:03seen before it allows also a middle ear
  709. 37:07pressure to equalize with atmospheric
  710. 37:11pressure so you can see those fringe of
  711. 37:16tympanic tubes they open into the
  712. 37:19lateral walls of the nasal pharynx
  713. 37:27and then here we have the uvula we said
  714. 37:30it was a pendulous structure moves
  715. 37:32superiorly which is gonna be an action
  716. 37:36that's gonna help to close off the nasal
  717. 37:38pharynx when we're swallowing right
  718. 37:42because we want food to make its way
  719. 37:43down into the esophagus we described
  720. 37:47here we have the oral pharynx then the
  721. 37:50oral pharynx found lying posterior to
  722. 37:52the oral cavity it's continuous with
  723. 37:56that oral cavity through the archway
  724. 37:58here that's known as the isthmus of the
  725. 38:01fauci's it's like a constricted region
  726. 38:03here it becomes a small let's see
  727. 38:06isthmus and then you can see it widens
  728. 38:08back out I knew the word always I didn't
  729. 38:16really understand until I got to
  730. 38:17Catalina Island I like to hike on and
  731. 38:19camp on this side and it's there's an
  732. 38:24isthmus there in the water basically
  733. 38:26it's where you can see the island
  734. 38:28instead of it being completely huge on
  735. 38:31the sides it kind of comes in and then
  736. 38:33it widens back out and this is like the
  737. 38:37area where we like to stay up and then
  738. 38:39come back here to the secluded area as
  739. 38:40well so isthmus is the term you're
  740. 38:43trying to understand next in here we
  741. 38:45have basically the oral pharynx I'd like
  742. 38:50you to know is gonna be lined by a
  743. 38:51protective stratified squamous
  744. 38:52epithelium so it's lined by a protective
  745. 38:55stratified squamous epithelium next in
  746. 39:02are the Palatine and lingual tonsils so
  747. 39:04here you can appreciate Palatine tonsils
  748. 39:06and then lingual tonsils we've got right
  749. 39:08here as well
  750. 39:09now Palatine tonsils are going to be
  751. 39:12pear if I was a pear they're lying
  752. 39:14embedded in the oral pharyngeal mucosa
  753. 39:17they're found lying embedded in the oral
  754. 39:22pharyngeal mucosa of the lateral walls
  755. 39:25of the fauci's the lingual the lingual
  756. 39:32are going to be found covering the
  757. 39:33posterior surface of the tongue again
  758. 39:37protecting the entrance into
  759. 39:41the pharynx you can see that pharynx is
  760. 39:44heavily guarded by security that are
  761. 39:49there to trap and destroy pathogens that
  762. 39:52may be entering into the pharynx the
  763. 39:56Palatine tonsils most oftenly infected
  764. 40:02the laryngopharynx the laryngopharynx is
  765. 40:05found located below you can see inferior
  766. 40:08to the oral pharynx below the oral
  767. 40:10pharynx it serves along with that oral
  768. 40:14pharynx it serves as a passageway for
  769. 40:19food air and liquids and it's line by
  770. 40:27stratified squamous right
  771. 40:35non-keratinized if you recall let's talk
  772. 40:40then larynx we're not going to move down
  773. 40:42here because we've already done that
  774. 40:44right we talked about the inferior
  775. 40:46continuation of the laryngopharynx and
  776. 40:48we said that was the esophagus so
  777. 40:51anterior to the lowering of fangs we
  778. 40:53could move into the larynx so let's zoom
  779. 40:55in on this structure right inside of
  780. 40:58here when we zoom in on this structure
  781. 41:00right inside of here this is what we
  782. 41:02have then anterior view posterior view
  783. 41:08and a medial view here's the tongue
  784. 41:12right no no that's your epiglottis you
  785. 41:16have the glottis cut in half right
  786. 41:21through the middle that's what we're
  787. 41:22seeing here so let's go through the
  788. 41:25larynx so nice anterior view the larynx
  789. 41:27is going to be your voice box
  790. 41:29aka your voice box it extends it extends
  791. 41:34about two inches it extends about two
  792. 41:36inches from c3 to c6 extends about two
  793. 41:41inches from c3 okay to about c6
  794. 41:48superiorly it attaches to the hyoid bone
  795. 41:53you can see that there and we resume
  796. 41:54on this you can see that they're very
  797. 41:57nicely it opens into the laryngopharynx
  798. 42:02the larynx opens into the laryngopharynx
  799. 42:08inferiorly it is continuous with the
  800. 42:10trachea inferior Li you can see it's
  801. 42:14continuous with the trachea now here is
  802. 42:19all trachea two main tasks we talk
  803. 42:24function let's top function function
  804. 42:27there's two main tasks number one it's
  805. 42:29to provide will see two main tasks are
  806. 42:32going to be to provide number one and
  807. 42:35open a patent airway so number one it's
  808. 42:38to provide a patent or an open airway
  809. 42:41number two its function is to act as a
  810. 42:44switching mechanism its function is to
  811. 42:47act as a switching mechanism so that way
  812. 42:50you can route food to its proper place
  813. 42:53and air to its proper place right even
  814. 42:56if we don't allow it to happen if we
  815. 42:58start to breed when we're swallowing
  816. 43:01that leads to them the food content
  817. 43:03making its way to the wrong tube we set
  818. 43:05the wrong when we say the wrong in
  819. 43:08laymen terms went down the wrong pipe
  820. 43:10and that's exactly what you see is
  821. 43:12happening there so next time here the
  822. 43:16third function third function is its
  823. 43:18involved with voiced production voice
  824. 43:20production and we're going to see the
  825. 43:22vocal cords in here that'll be
  826. 43:24responsible for that voice production so
  827. 43:27let's go through the clip of the
  828. 43:28structure let's look at the structure of
  829. 43:30wiring so when we look at the structure
  830. 43:31of the larynx it's made up of an
  831. 43:33intricate arrangement it's got an
  832. 43:36intricate arrangement of nine cartilages
  833. 43:39that are connected by membranes and by
  834. 43:42ligaments except for the epiglottis
  835. 43:50which is made up of elastic cartilage
  836. 43:54all laryngeal cartilages are hyaline
  837. 43:57cartilage okay so you got to make sure
  838. 44:00we've got that established there thyroid
  839. 44:02cartilage we could look at first so here
  840. 44:04we've got our thyroid cartilage and we
  841. 44:05talked about the thyroid cartilage the
  842. 44:07thyroid cartilage
  843. 44:08a nice large shield shaped cartilage
  844. 44:12it's formed by the fusion of these two
  845. 44:18cartilage plates and here you can see
  846. 44:21that fusion we have at the point of the
  847. 44:24fusion what we call the laryngeal
  848. 44:26prominence or Adam's apple so it's a
  849. 44:31midline where the two cartilage plates
  850. 44:38come together we have a nice learned
  851. 44:42your prominence there Adam's apple there
  852. 44:44so he marks the fusion point this
  853. 44:47thyroid cartilage in males is much
  854. 44:50larger in size why very good
  855. 44:56testosterone okay so nice thyroid
  856. 45:01cartilage we can appreciate their then
  857. 45:03here we could see the creek oi cartilage
  858. 45:05creek or cartilage quick quick cartilage
  859. 45:07is inferior to the thyroid cartilage it
  860. 45:10is ring shaped ring shaped so look at
  861. 45:15the back when we look at the back let's
  862. 45:17see here
  863. 45:18you can see the thyroid card is not good
  864. 45:20ring shape so it's not going all the way
  865. 45:21around but right in here the creek Koide
  866. 45:23is coming all the way around so this is
  867. 45:24the back part of it that's the front
  868. 45:26that we've been looking at that's what
  869. 45:28you're seeing here it's found perched a
  870. 45:34talked and anchored to the trachea
  871. 45:37inferiorly so it's found on top of and
  872. 45:40anchored to the trachea which is found
  873. 45:44inferior to it let's
  874. 45:51turn this larynx around and here we can
  875. 45:56appreciate them so you're gonna say we
  876. 45:58you said nine cartilages we've only gone
  877. 46:01through two and here you can see now one
  878. 46:06two three pairs so that's two total
  879. 46:09there and in pairs so that's two two two
  880. 46:12six seven we talked about eight we
  881. 46:17talked about in the ninth we'll do that
  882. 46:18big log okay so let's talk eret annoyed
  883. 46:21cartilage error - annoyed cartilages you
  884. 46:23can appreciate here this nice triangular
  885. 46:26pyramid shaped cartilage nice pyramid
  886. 46:30shaped cartilage it's the most important
  887. 46:35one here because it's going to anchor
  888. 46:37the vocal folds it will anchor the vocal
  889. 46:41folds and then we can see right above it
  890. 46:48see it right above it perched above it
  891. 46:50curricula cartilage also found as a pair
  892. 46:53curricula cartilage and then here we've
  893. 46:57got on the lateral walls the cuneiform
  894. 47:01cartilages also found as a pair so it's
  895. 47:04two four six seven eight cartilages that
  896. 47:08we have taken care of now these three
  897. 47:10pairs of small these three pairs are
  898. 47:13small cartilages they form part of the
  899. 47:16lateral and posterior walls of the
  900. 47:19larynx and again the air tuner is the
  901. 47:22most important there then the last
  902. 47:26cartilage epiglottis the ninth cartilage
  903. 47:29it's flexible it's spoon shaped it's
  904. 47:33composed of elastic cartilage and is
  905. 47:38almost entirely covered by tastebud
  906. 47:41containing mucosa in fur in class you
  907. 47:48would really impress me if you were able
  908. 47:49to tell me basically what nerve is gonna
  909. 47:52be providing innervation to that area
  910. 47:54very good I knew you all knew right we
  911. 48:02said seven in the front
  912. 48:049 is what we have in the back rack 10
  913. 48:11making our way all the way to the back
  914. 48:13okay so tent nerd next then we've got
  915. 48:18our sole epiglottis is taken care of our
  916. 48:21epiglottis almost entirely covered by
  917. 48:23taste but continued mucosa and you can
  918. 48:25see the epiglottis is gonna be found
  919. 48:26extending from the posterior aspect of
  920. 48:29the tongue so it's extending from the
  921. 48:31posterior aspect of the tongue let me
  922. 48:33show it to you there very well or you
  923. 48:35can see it here very well so it's
  924. 48:40extending from the posterior aspect of
  925. 48:42the tongue to its anchoring point to its
  926. 48:47anchoring point on the anterior rim of
  927. 48:50that thyroid cartilage so let's zoom in
  928. 48:54on this - its anchoring point on the
  929. 49:04anterior room of the thyroid cartilage
  930. 49:08vocal folds you can see here and
  931. 49:12vestibular folds we could see right
  932. 49:14above and kind of lateral to them so
  933. 49:16let's look at them from a better view so
  934. 49:19here this view you can see first let's
  935. 49:21orient ourselves we have the tongue here
  936. 49:23right so the oral cavity is about in
  937. 49:25this area here we've got the tongue so
  938. 49:27moving to the back of the tongue is what
  939. 49:28we see here so basically what we have
  940. 49:30here is you've got your patient lying
  941. 49:32down and you're looking down into that
  942. 49:34oral cavity you're looking at the top
  943. 49:36and basically you're looking from here
  944. 49:39and your patient is lying down and
  945. 49:40you're looking down into this area right
  946. 49:43in here with their head tilted back okay
  947. 49:46you're looking right into this area here
  948. 49:48that's what this view here is so here
  949. 49:52that we can appreciate first your vocal
  950. 49:55folds your vocal folds of your true
  951. 49:57vocal cords your true vocal cords you
  952. 50:01can see here very nicely and here very
  953. 50:04nicely also known as mucosal folds they
  954. 50:08are pearly white in color pearly white
  955. 50:11in color because they lack blood vessels
  956. 50:14because they lack blood vessels their
  957. 50:17core
  958. 50:18their core is going to be formed by
  959. 50:20ligaments and they're composed of
  960. 50:24elastic fibers these ligaments again
  961. 50:32they're composed largely of elastic
  962. 50:34fibers next we have the glottis the
  963. 50:40glottis is the area from one end of you
  964. 50:45could see those vocal folds to the other
  965. 50:49end of the vocal folds this is the
  966. 50:55opening through which air passes to make
  967. 51:01its way into the lungs glottis has to be
  968. 51:12patent we maintain a patent it's open
  969. 51:16right the only time it closes is during
  970. 51:20swallowing during swallowing next thing
  971. 51:25you have your vestibular folds your
  972. 51:27vestibular folds and we talked about the
  973. 51:29vestibular folds you can appreciate the
  974. 51:30vestibular folds here we said superior
  975. 51:32lateral to the vocal folds so that's
  976. 51:37tubular folds your false vocal cords or
  977. 51:41false mucosal folds their superior and
  978. 51:45lateral to the vocal folds like humps
  979. 51:49kind of you can dink on the sides and
  980. 51:55then we have our trachea so this will
  981. 51:58then lead us down to the trachea we talk
  982. 52:02trachea trick is your windpipe so let's
  983. 52:04focus on the trachea so here we have a
  984. 52:07trachea and we'll talk about the trachea
  985. 52:08your windpipe it descends it descends
  986. 52:13from the larynx through the neck and
  987. 52:16into the mediastinum it ends by dividing
  988. 52:23into the two main bronchi at mid thorax
  989. 52:33the trachea is about four inches long
  990. 52:37and has a diameter of about
  991. 52:42three-quarters of an inch so 3/4 of an
  992. 52:46inch diameter it's flexible and mobile
  993. 52:52as well it's flexible and mobile now
  994. 52:59when we talk about the histology when we
  995. 53:01focus in on the histology here we can
  996. 53:03appreciate that let's zoom in on
  997. 53:05basically the same thing here you could
  998. 53:08see now we are going to see it's made up
  999. 53:11of mucosa number one so here we could
  1000. 53:14see we've got mucosa submucosa and then
  1001. 53:18we've got hyaline cartilage underneath
  1002. 53:20so let's zoom in on that mucosa the
  1003. 53:23mucosa is going to contain goblet cells
  1004. 53:29so pseudostratified we can see there
  1005. 53:33pseudostratified columnar ciliated
  1006. 53:37epithelium that will contain goblet
  1007. 53:41cells and it has a thick lamina propria
  1008. 53:48has a thick lamina propria with a rich
  1009. 53:53supply of elastic fibers providing its
  1010. 53:57support
  1011. 54:00so all making up the mucosa see yuga
  1012. 54:05epithelium and lamina propria next and
  1013. 54:13we can appreciate the submucosa when we
  1014. 54:15talk about the submucosa you can see the
  1015. 54:18submucosa is special here as well
  1016. 54:20because it contains glands also the
  1017. 54:22submucosa is the connective tissue layer
  1018. 54:25that's deep to the mucosa and it
  1019. 54:30contains saero mucous glands the
  1020. 54:36submucosa is supported by 16 to 20 C
  1021. 54:42shaped
  1022. 54:45rings of hyaline cartilage that are
  1023. 54:51encased by adventitia that are encased
  1024. 54:55by adventitia so adventitia then you can
  1025. 55:00appreciate here is the outermost layer
  1026. 55:02of connective tissue next then let's
  1027. 55:09move back and let's talk about the
  1028. 55:12Carina the Carina is found on the lowest
  1029. 55:18tracheal cartilage this Carina it you
  1030. 55:23can see as projecting you really can't
  1031. 55:26see that here but it's going to be found
  1032. 55:27projecting posteriorly it kind of
  1033. 55:31projects posteriorly and basically marks
  1034. 55:35the point where the trachea divides
  1035. 55:37where the trachea ends and it divides
  1036. 55:43and you can see the trachea branches it
  1037. 55:46branches into two main bronchi we said
  1038. 55:52the two primary bronchi so here then we
  1039. 55:57can see the bronchial tree will begin
  1040. 55:59now the bronchial tree is the branching
  1041. 56:02pattern of the Airways that we can
  1042. 56:05appreciate here so it starts with the
  1043. 56:09bronchi the right and left bronchi the
  1044. 56:12right and left main bronchi or primary
  1045. 56:15bronchi we said they are going to be
  1046. 56:18formed when the trachea is going to
  1047. 56:21split and divide the trachea splits and
  1048. 56:26divides we said here at the Carina and
  1049. 56:28this Carina has found at the level of t7
  1050. 56:33thoracic vertebra number seven around t7
  1051. 56:37the right primary main bronchi is wider
  1052. 56:43it's shorter and it's also more vertical
  1053. 56:50compared to the left
  1054. 56:55so keeping that in mind I'd like you to
  1055. 56:57know foreign bodies objects become
  1056. 57:00lodged in this right side much more
  1057. 57:03easier compared to than this light this
  1058. 57:06left side so as we said these primary
  1059. 57:12bronchi are going to make their way
  1060. 57:13deeper into the lungs and they'll branch
  1061. 57:15and here you can see they branch into
  1062. 57:18then the low bar or the secondary
  1063. 57:22bronchi the low bar or the secondary
  1064. 57:25bronchi the low bar or secondary bronchi
  1065. 57:28now these low bar secondary bronchi are
  1066. 57:30subdivisions of the main bronchi there
  1067. 57:33are three on the right and two on the
  1068. 57:36left
  1069. 57:37each supplying a lung lobe they will
  1070. 57:45then enter further into the lungs and
  1071. 57:47divide for me the segments or tertiary
  1072. 57:51bronchi segmental or tertiary bronchi
  1073. 57:59now these segments or tertiary bronchi
  1074. 58:01are subdivisions of each lobe are
  1075. 58:03bronchi and they themselves are going to
  1076. 58:06divide into smaller bronchi as well
  1077. 58:09eventually forming for us the
  1078. 58:12bronchioles or we refer to as the little
  1079. 58:16bronchi these are passages that are
  1080. 58:19smaller than one millimeter in diameter
  1081. 58:23when we talk bronchioles now it took
  1082. 58:26bronchioles let's move into the
  1083. 58:28bronchioles the bronchioles now are made
  1084. 58:30up of you can see basically starting
  1085. 58:34with the terminal bronchioles moving
  1086. 58:35into the respiratory bronchus and then
  1087. 58:37all the way through to the alveoli so we
  1088. 58:40talk bronchioles little bronchi are
  1089. 58:42smaller passages that are smaller than
  1090. 58:44one millimeter in diameter so first
  1091. 58:46let's talk terminal now bronchioles so
  1092. 58:50from the bronchioles we reach the
  1093. 58:52terminal bronchioles now terminal
  1094. 58:53bronchioles are gonna be even smaller
  1095. 58:54branches basically now the terminal
  1096. 58:56bronchioles are the tiniest bronchioles
  1097. 59:01that we've seen so far
  1098. 59:03and these terminal bronchioles are
  1099. 59:05passageways that are less than 0.5
  1100. 59:09millimeters in diameter and we said now
  1101. 59:15at the terminal bronchioles this is
  1102. 59:17where the conducting zone ends leading
  1103. 59:20us then to the respiratory bronchioles
  1104. 59:22now the respiratory bronchioles are
  1105. 59:24within the lung this is the area where
  1106. 59:30we set our respiratory zone begins and
  1107. 59:32they will lead us to the alveolar ducts
  1108. 59:36the alveolar ducts then they're
  1109. 59:41consisting of diffusely arranged rings
  1110. 59:44of smooth muscle cells as we can see
  1111. 59:49along the terminal bronchioles and
  1112. 59:52respiratory bronchioles also smooth
  1113. 59:55muscle so when you talk asthma this is
  1114. 59:58going to be one of the mechanisms that
  1115. 59:59can initiate asthma by causing a
  1116. 1:00:02constriction of those passageways the
  1117. 1:00:04other is inflammation within that
  1118. 1:00:07bronchial itself leading to the pathway
  1119. 1:00:11the passageway the pathway being shut
  1120. 1:00:13off right because of inflammation inside
  1121. 1:00:15sometimes then you can have both happen
  1122. 1:00:19bronchospasms due to the muscle and also
  1123. 1:00:22inflammation so then you need both
  1124. 1:00:25medications so now when we go through we
  1125. 1:00:28talk about the alveolar sacs let's talk
  1126. 1:00:31about the alveolar sacs the alveolar
  1127. 1:00:32sacs are gonna be tiny clusters so here
  1128. 1:00:34you can see one alveolar sac is another
  1129. 1:00:36alveolar sac tiny clusters of grapes you
  1130. 1:00:38can think of tiny clusters of alveolar
  1131. 1:00:41of alveoli the alveolar sacs so now
  1132. 1:00:44let's look at the alveoli themselves all
  1133. 1:00:46right because we need to see what one
  1134. 1:00:47alveoli looks like so here you can
  1135. 1:00:49appreciate the microscopic basically
  1136. 1:00:53depiction the respiratory bronchioles
  1137. 1:00:55leading to then a whole bunch of alveoli
  1138. 1:00:56you've seen all these alveoli in class
  1139. 1:00:58right on the first exam you're able to
  1140. 1:01:01go through and identify everything that
  1141. 1:01:03you had in here so here when we look at
  1142. 1:01:07those alveoli in greater detail this is
  1143. 1:01:09what we're seeing okay same thing we're
  1144. 1:01:13seeing here now these alveoli they're
  1145. 1:01:15made up you can see here of a whole
  1146. 1:01:17bunch of different cells so now these
  1147. 1:01:19alveoli a long width you can see
  1148. 1:01:23the actual blood vessel are going to
  1149. 1:01:29help make up what's called the
  1150. 1:01:30respiratory membrane so we talk a
  1151. 1:01:31respiratory membrane the respiratory
  1152. 1:01:32membrane is formed by the alveolar walls
  1153. 1:01:36and the alveolar walls are made up
  1154. 1:01:40themselves where's my mouse you know we
  1155. 1:01:43could see the alveolar walls themselves
  1156. 1:01:45are made up of primarily a single layer
  1157. 1:01:49of squamous epithelial cells right we've
  1158. 1:01:53seen those they are also known as type 1
  1159. 1:01:55pneumo sites scattered in between these
  1160. 1:01:59cells are type tunable sites which
  1161. 1:02:03produce surfactant and also
  1162. 1:02:07antimicrobial proteins surfactant
  1163. 1:02:11decreases surface tension and it's
  1164. 1:02:15produced around 24 weeks in the fetus
  1165. 1:02:20around 24 weeks in the fetus so anything
  1166. 1:02:26that's basically born before that it's
  1167. 1:02:29going to require intervention compared
  1168. 1:02:37to 1 after that in relation to you know
  1169. 1:02:42pulmonary intervention next in here we
  1170. 1:02:45can see also we have so type 1 and type
  1171. 1:02:482 cells and we also have macrophages we
  1172. 1:02:50can appreciate inside of there as well
  1173. 1:02:52okay so that's one part of the
  1174. 1:02:55respiratory membrane and then on the
  1175. 1:02:57other side you can see you've got the
  1176. 1:02:58actual blood vessels this is the
  1177. 1:03:01pulmonary circulation we talked about so
  1178. 1:03:03here then you've got stuck here so we
  1179. 1:03:12can appreciate okay
  1180. 1:03:15the endothelial cells of the blood
  1181. 1:03:17vessels again simple squamous epithelia
  1182. 1:03:19and then here between the two you've got
  1183. 1:03:22the fused basement membranes of the two
  1184. 1:03:26so that makes up your respiratory
  1185. 1:03:28membrane that makes up your respiratory
  1186. 1:03:31membrane you've got basically blood on
  1187. 1:03:33one side and gas on the other and
  1188. 1:03:34exchange is happening you learn
  1189. 1:03:37in biology thanks to we also talked
  1190. 1:03:40about in here as well
  1191. 1:03:41diffusion right movement from an area of
  1192. 1:03:46high to low
  1193. 1:03:47thanks to concentration differences so
  1194. 1:03:51I'll just buy you that one word
  1195. 1:03:52diffusion see what bio teaches you bio
  1196. 1:03:56is a very important class that's why
  1197. 1:03:58it's a prereq here next let's talk about
  1198. 1:04:02the lungs themselves let's get into the
  1199. 1:04:04lungs so when we talk about the lungs
  1200. 1:04:06lungs are going to be found as a pair
  1201. 1:04:08they occupy all the thoracic cavity
  1202. 1:04:12except for the mediastinum right because
  1203. 1:04:15the mediastinum then you can see is
  1204. 1:04:16occupied by other structures the
  1205. 1:04:19function of the lungs is to transport
  1206. 1:04:22oxygen from the atmosphere into the
  1207. 1:04:24bloodstream and to release carbon
  1208. 1:04:27dioxide from the bloodstream into the
  1209. 1:04:29atmosphere now when we talk about the
  1210. 1:04:33structures in relation to the lungs
  1211. 1:04:35first we can appreciate here the apex of
  1212. 1:04:38the lung so the apices we can see in
  1213. 1:04:41relation to both lungs the apex is the
  1214. 1:04:44narrower superior tip of the lungs and
  1215. 1:04:48you can see here it's found deep to the
  1216. 1:04:51clavicles deep to the clavicles I tell
  1217. 1:04:54my physiology students when you need to
  1218. 1:04:56listen when you need to auscultate the
  1219. 1:04:59apices you're going to auscultate above
  1220. 1:05:01the clavicles above the clavicles next
  1221. 1:05:08thing we have the base the opposite
  1222. 1:05:09usually to the APUs to the apex the base
  1223. 1:05:12is going to be as it's going to be found
  1224. 1:05:14as concave it's found as a concave
  1225. 1:05:18region it's going to be found at the
  1226. 1:05:24inferior surface of the lungs and the
  1227. 1:05:28base rests on top of the diaphragm a
  1228. 1:05:31rests on top of the diaphragm
  1229. 1:05:39next then we've got the hilum we can
  1230. 1:05:43appreciate the pulmonary high lung we
  1231. 1:05:47talk pulmonary hilum this is basically
  1232. 1:05:50an indentation on the medial surface of
  1233. 1:05:54each of the lungs where you'll see the
  1234. 1:05:59blood vessels the bronchi lymphatic
  1235. 1:06:06vessels and nerves enter and exit the
  1236. 1:06:12lungs so this is all that pulmonary
  1237. 1:06:16hilum now we can also appreciate here
  1238. 1:06:23our pleura the pleura you can see is
  1239. 1:06:27nice and continuous with each other
  1240. 1:06:31right because when we talk to each other
  1241. 1:06:33there's two different layers you have a
  1242. 1:06:34Vista when you have a parietal you can
  1243. 1:06:38see that there very nicely so way back
  1244. 1:06:39to lungs left lung is going to be
  1245. 1:06:42slightly smaller it gets divided into
  1246. 1:06:46two lobes a superior and an inferior
  1247. 1:06:49lobe these are the subdivisions and the
  1248. 1:06:55oblique fissure is responsible for
  1249. 1:06:59dividing you can see those two loads
  1250. 1:07:01from one another oblique fissure because
  1251. 1:07:08of the way it comes in and then we got
  1252. 1:07:12we've got the cardiac notch now the
  1253. 1:07:15cardiac notch is going to be found you
  1254. 1:07:19can see on the medial surface of that
  1255. 1:07:21left lung and that cardiac notch is a
  1256. 1:07:24concavity
  1257. 1:07:26it's a concavity on the medial aspect
  1258. 1:07:29and this cardiac notch is molded too and
  1259. 1:07:34it accommodates the heart so that's why
  1260. 1:07:37this side you can see is a little bit
  1261. 1:07:38smaller this lung compared to the right
  1262. 1:07:41that heart is going to be occupying you
  1263. 1:07:43can see most of the space right in here
  1264. 1:07:49next time we talk right lung right lung
  1265. 1:07:52divided up into three lobes you've got a
  1266. 1:07:55superior lobe a middle lobe and an
  1267. 1:07:58inferior lobe and these subdivisions you
  1268. 1:08:02can see they're very nicely the superior
  1269. 1:08:04lobe is divided from the medial herbs
  1270. 1:08:07from the middle lobe
  1271. 1:08:08thanks to you can see this horizontal
  1272. 1:08:10fissure the middle lobe is subdivided
  1273. 1:08:14from this inferior lobe thanks to the
  1274. 1:08:16oblique fissure so again they help
  1275. 1:08:26divide the lung into three lobes these
  1276. 1:08:29fissures next then we talk about our
  1277. 1:08:33bronchopulmonary segments now I'd like
  1278. 1:08:38you to know each of these
  1279. 1:08:39bronchopulmonary segments are going to
  1280. 1:08:41be served by their own artery and vein
  1281. 1:08:45so that exemplifies the dual circulation
  1282. 1:08:49that we're going to see in relation to
  1283. 1:08:50the lungs then we talk about lung tissue
  1284. 1:08:56lung tissue is basically mostly elastic
  1285. 1:09:00connective tissue it's mostly elastic
  1286. 1:09:04connective tissue and we use the term
  1287. 1:09:11given our stroma so stroma is going to
  1288. 1:09:15be a term describing basically lung
  1289. 1:09:17tissue and how it's made up of mostly of
  1290. 1:09:19elastic connective tissue and then again
  1291. 1:09:21it provides support to the epithelium so
  1292. 1:09:24stroma is basically the support for the
  1293. 1:09:26epithelia we could see there next time
  1294. 1:09:28let's talk about let's talk about our
  1295. 1:09:32pleura so I talked pleura pleura always
  1296. 1:09:35described as being thin double layered
  1297. 1:09:39right you've got pride on you got
  1298. 1:09:40visceral then double layered serosa so
  1299. 1:09:43one layer lining the cavity and one
  1300. 1:09:45layer right on top of the lung it's on
  1301. 1:09:46the lung you can't even separate the two
  1302. 1:09:48from each other the lung and the
  1303. 1:09:49visceral pleura they're that adhere to
  1304. 1:09:51one another so here and then the
  1305. 1:09:53visceral the pride are continuous with
  1306. 1:09:55one another you could see here as well
  1307. 1:09:56again so here now when you talk a pleura
  1308. 1:10:02double-layered serous member
  1309. 1:10:03between the two then your pleural cavity
  1310. 1:10:05contains pleural fluid which is going to
  1311. 1:10:08help prevent friction amongst other
  1312. 1:10:10things there as well now when you talk
  1313. 1:10:11muscles of respiration
  1314. 1:10:12so you took muscles of respiration here
  1315. 1:10:14then we get into first the diaphragm
  1316. 1:10:17also in the external intercostal muscles
  1317. 1:10:19they are the muscles of inspiration
  1318. 1:10:22now when the diaphragm muscles activated
  1319. 1:10:24thanks to we've seen the different nerve
  1320. 1:10:26so this is all coming into play now this
  1321. 1:10:29will cause the muscle to flatten and
  1322. 1:10:31then we've talked about how we have
  1323. 1:10:32pleura coming down this will cause the
  1324. 1:10:34pleura to then pull be pulled on as well
  1325. 1:10:37and that causes the lung to be pulled on
  1326. 1:10:39so that causes along them to expand
  1327. 1:10:41helping to get air in along with that
  1328. 1:10:43the external cost those are gonna pull
  1329. 1:10:45you can see those lungs up and out and
  1330. 1:10:49when they pull the Mons up and out again
  1331. 1:10:51you've got pleura private pleura on the
  1332. 1:10:53inside we pull that private pleura as
  1333. 1:10:55well which then pulls on the visceral
  1334. 1:10:58which then is adhered on to the lungs
  1335. 1:11:00which pulls on the lungs again causing
  1336. 1:11:02air to make its way into the lungs in an
  1337. 1:11:04opposite you've got external you've got
  1338. 1:11:07expiration now an expiration the
  1339. 1:11:10internal intercostals are gonna come
  1340. 1:11:11together and they're going to cause
  1341. 1:11:13you'll see the ribs to be depressed and
  1342. 1:11:16pushed down basically which is going to
  1343. 1:11:18then cause the air to be pushed out of
  1344. 1:11:20the lungs along with them you can see
  1345. 1:11:22you've got these other muscles in here
  1346. 1:11:24as well and these other muscles of the
  1347. 1:11:26chest the neck and the abdomen are also
  1348. 1:11:28then going to be involved there as well
  1349. 1:11:30helping to get air out of the lungs now
  1350. 1:11:33all of this is going to be controlled by
  1351. 1:11:35the you can see respiratory centers
  1352. 1:11:39which are gonna be found not only in
  1353. 1:11:41ponds but the medulla but then also
  1354. 1:11:44higher brain centers you can see are
  1355. 1:11:45involved there as well higher brain
  1356. 1:11:47centers are going to influence the
  1357. 1:11:48pontine respiratory group the PRG
  1358. 1:11:51the pontine respiratory group then is
  1359. 1:11:53going to you can see influence the
  1360. 1:11:55Ventura on the dorsal respiratory groups
  1361. 1:11:57the vrg and the DRG which then also are
  1362. 1:12:00influenced by chemo receptors okay and
  1363. 1:12:03these chemo receptors are gonna be found
  1364. 1:12:05located you will see in various
  1365. 1:12:06locations so here we could see the
  1366. 1:12:08respiratory centers of the medulla pons
  1367. 1:12:10right inside of here and they modify
  1368. 1:12:13breathing not only modifying breathing
  1369. 1:12:15but also
  1370. 1:12:17the pace the rate and the depth of
  1371. 1:12:20breathing we can see here but then also
  1372. 1:12:22now the input sources we have here are
  1373. 1:12:26gonna include chemoreceptors we
  1374. 1:12:27mentioned central chemoreceptors and
  1375. 1:12:29peripheral chemoreceptors there
  1376. 1:12:30chemoreceptors so you have to understand
  1377. 1:12:32that now but now exactly what they're
  1378. 1:12:34monitoring stretch receptors irritate
  1379. 1:12:37receptors and also higher brain centers
  1380. 1:12:38the cortex that the hypothalamus and in
  1381. 1:12:41the limbic system all involved with then
  1382. 1:12:45breathing

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