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Addiction I Full Documentary I NOVA I PBS — Transcript

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  1. 0:01♪ ♪
  2. 0:03NARRATOR: A devastating epidemic...
  3. 0:05KEN: We just didn't know what to do.
  4. 0:07We just felt powerless.
  5. 0:09A parents' worst nightmare,
  6. 0:12to find my kid not breathing.
  7. 0:16JAMES WINNEFELD: He was always very good
  8. 0:17at telling us, "Mom and Dad, everything's going to be fine,"
  9. 0:20but it wasn't.
  10. 0:23NARRATOR: Addiction is ruining lives
  11. 0:25and ending them too soon.
  12. 0:27(alarm blaring)
  13. 0:28Overdose is the number one cause of death
  14. 0:30for people under 50.
  15. 0:32RAHUL GUPTA: We are racing against time.
  16. 0:34We have the equivalent
  17. 0:36of a Boeing 737 crashing every single day.
  18. 0:39NARRATOR: But what causes addiction?
  19. 0:42ROBERT MALENKA: Individuals struggling with addiction
  20. 0:44are actually battling millions of years of evolution,
  21. 0:48because our brains are exquisitely evolved,
  22. 0:52to seek rewards.
  23. 0:54It's those cravings, the inability to stop.
  24. 0:59NARRATOR: A dangerous cocktail of biology and medicine
  25. 1:03made deadlier by a drug 100 times more potent
  26. 1:07than morphine.
  27. 1:08DARWIN FISHER: Fentanyl is super toxic.
  28. 1:10So you get a batch that comes on the street
  29. 1:13that's a little bit hot,
  30. 1:14and on those days, it's like,
  31. 1:16bam, somebody's going down.
  32. 1:18Bam, somebody's going down.
  33. 1:20Bam!
  34. 1:22NARRATOR: But can new treatments offer hope?
  35. 1:25LAURA KEHOE: We have extremely effective medications
  36. 1:28that are life-saving.
  37. 1:30This is a very treatable illness.
  38. 1:32ANNA LEMBKE: The solution to this
  39. 1:34is for us to embrace addiction as a disease,
  40. 1:38to bring it within the house of medicine.
  41. 1:40FISHER: People recover from addiction.
  42. 1:42Nobody is unreclaimable.
  43. 1:46The only thing that you can't recover from
  44. 1:49is death.
  45. 1:50NARRATOR: "Addiction,"
  46. 1:52on "NOVA."
  47. 1:56♪ ♪
  48. 2:08♪ ♪
  49. 2:10NARRATOR: McDowell County, West Virginia,
  50. 2:13feels like a place left behind.
  51. 2:18Yet its miners helped power America
  52. 2:21when coal was king.
  53. 2:26Back then, the largest city, Welch,
  54. 2:30was a thriving community.
  55. 2:32But as coal jobs vanished by the 1990s,
  56. 2:36the poverty rate in the county
  57. 2:38climbed to 38%.
  58. 2:43Then investigators found
  59. 2:45that over a six-year period,
  60. 2:47drug companies had flooded the state
  61. 2:49with 780 million highly addictive pain pills.
  62. 2:53(train horn blaring)
  63. 2:58(rumbling)
  64. 3:04JASEN EDWARDS: West Virginia was the perfect storm.
  65. 3:07The whole state's dominated
  66. 3:08by one of the hardest and most dangerous jobs
  67. 3:10in the world.
  68. 3:11Most of the old timers that work in the mines
  69. 3:14work with pain.
  70. 3:15And then pain pills started flooding the community,
  71. 3:18and people that you used to know
  72. 3:21weren't the same people that they used to be.
  73. 3:24I mean, it, it just... it ruined everything.
  74. 3:28♪ ♪
  75. 3:30NARRATOR: Jasen Edwards and his two brothers Scott and Mark,
  76. 3:33grew up in Sophia, West Virginia.
  77. 3:38The town was near the Winding Gulf coal field.
  78. 3:42Most of its residents were miners,
  79. 3:46including the Edwards family.
  80. 3:49All three sons would struggle with pain pills.
  81. 3:55Jasen got his first prescription
  82. 3:57after crushing his leg in a mining accident.
  83. 4:02They cut my leg off the day after Christmas in 2008,
  84. 4:07and I was back underground mid-to-late February.
  85. 4:12First day I went back to work,
  86. 4:15I had to crawl everywhere or ride everywhere I went,
  87. 4:19because my stump was still too swollen
  88. 4:22to put my prosthetic leg on.
  89. 4:25A man hurts his back,
  90. 4:27if he is not back to work, they will replace him.
  91. 4:30And I could not have supported my family on the disability.
  92. 4:34NARRATOR: Soon, a few pills a day
  93. 4:37could no longer stop the pain.
  94. 4:38(drill grinding)
  95. 4:41But Jasen could easily buy more
  96. 4:44by visiting doctors and showing his artificial leg.
  97. 4:50JASEN: The first time I realized that I was in trouble
  98. 4:53is when I couldn't go to work,
  99. 4:54because I didn't have any pain pills.
  100. 4:57And it wasn't because of how bad I was hurting,
  101. 5:00it was because of the sickness due to detoxing.
  102. 5:04♪ ♪
  103. 5:06NARRATOR: Jasen was addicted to a powerful opioid painkiller
  104. 5:09called OxyContin.
  105. 5:13Opioids like OxyContin are chemically similar to morphine,
  106. 5:17found in the opium of the poppy plant.
  107. 5:20They mimic the body's natural pain relievers,
  108. 5:25like endorphins,
  109. 5:26which bind to proteins, called receptors,
  110. 5:29calming pain and inducing euphoria.
  111. 5:33Prolonged opioid use can alter the brain
  112. 5:37and lead to addiction,
  113. 5:38manifested by cravings and compulsive drug use
  114. 5:42despite negative consequences.
  115. 5:45♪ ♪
  116. 5:49As opioids were aggressively marketed,
  117. 5:51West Virginia soon had the highest rate of overdose deaths
  118. 5:54in the U.S.,
  119. 5:55alarming health commissioner Dr. Rahul Gupta.
  120. 5:59GUPTA: We were amongst the top states
  121. 6:02prescribing pain pills in the nation.
  122. 6:05At the same time,
  123. 6:07people were losing their employment,
  124. 6:08they were also losing a way of life.
  125. 6:11It spelled the perfect conditions under which
  126. 6:15addiction began to creep in.
  127. 6:18(indistinct talking)
  128. 6:21♪ ♪
  129. 6:26NARRATOR: At Stanford University,
  130. 6:28psychiatrist Anna Lembke
  131. 6:30also feared Big Pharma's pressure on doctors
  132. 6:32was creating an epidemic.
  133. 6:35When she got access to patients' prescriptions records,
  134. 6:39her suspicions were confirmed.
  135. 6:44Many people abusing pain pills
  136. 6:46were getting them from doctors-- not drug dealers.
  137. 6:50♪ ♪
  138. 6:53I'll never forget when I first looked at the drug database
  139. 6:56for a patient of mine.
  140. 6:57I mean, it was just glaringly obvious
  141. 7:00she'd been doctor shopping,
  142. 7:01you know, 1,600 pills, I think, in the span of a month.
  143. 7:04And I think it's important to know
  144. 7:06that doctors were being sued
  145. 7:08if they did not do everything within their power
  146. 7:11to address a patient's pain.
  147. 7:13So there was a serious problem going on here.
  148. 7:16NARRATOR: Lembke was also seeing a new type of patient--
  149. 7:21an "opioid refugee."
  150. 7:24(dog barking)
  151. 7:26KEN: How's your chemistry class coming?
  152. 7:27CASEY: It's fine.
  153. 7:30What are you guys working on in there?
  154. 7:31Compounds, chemical compounds,
  155. 7:33like iron...
  156. 7:34NARRATOR: Casey leads a protected life.
  157. 7:36Her father Ken watched drugs destroy his brothers,
  158. 7:41so he moved his daughters out of the city
  159. 7:43and put them in private schools.
  160. 7:49In her teens, Casey stayed busy with sports.
  161. 7:54But she began having severe muscle cramps.
  162. 7:58CASEY: I remember one game in particular,
  163. 8:01all of sudden I just started feeling really shaky
  164. 8:05and then everything just started hurting.
  165. 8:07My legs and my arms just cramped up really tight.
  166. 8:11She fell straight to the ground screaming in pain.
  167. 8:15It took me and one of her coaches to pick her up,
  168. 8:17put her in our car, rush her out to Children's.
  169. 8:21They did a million and one tests,
  170. 8:22and then they found, you know, an ovarian mass.
  171. 8:25Well, an ovarian mass in a teen, that's scary.
  172. 8:28So then that required more medical workup
  173. 8:31in order to discover that the mass was, in fact, benign,
  174. 8:34but by then, you know, she had a surgery,
  175. 8:36it had been removed,
  176. 8:37and through all of this,
  177. 8:38she received copious opioids.
  178. 8:41♪ ♪
  179. 8:44CASEY: Once I left the hospital,
  180. 8:45I noticed that I was still having a lot of pain,
  181. 8:48but it was nowhere near the surgery sites
  182. 8:51that they had operated on.
  183. 8:52KEN: We couldn't even touch her,
  184. 8:55she was in so much pain.
  185. 8:57She described it as
  186. 8:58it felt like her bones were being ripped out of her body.
  187. 9:01Now, the pain she was experiencing
  188. 9:04was opioid withdrawal pain, but they didn't know.
  189. 9:06So they whisk her back to the emergency room.
  190. 9:09"What could this possibly be?
  191. 9:10She's got terrible pain."
  192. 9:12And, essentially, every single time
  193. 9:14the solution was, "Prescribe more opioids."
  194. 9:17But after a while
  195. 9:18they didn't help as much anymore,
  196. 9:20so I started taking way too many.
  197. 9:24LEMBKE: Until at one point
  198. 9:25an emergency room doctor realized she's addicted,
  199. 9:29and what was his reaction?
  200. 9:30He basically went out and he shamed them.
  201. 9:32And he's like, "Your daughter's addicted.
  202. 9:34We never want to see her here again."
  203. 9:35NARRATOR: Stunned, Ken drove home,
  204. 9:39with no idea of how to help his daughter.
  205. 9:43Casey was now an opioid refugee,
  206. 9:46battling cravings and withdrawal on her own.
  207. 9:50We just felt powerless.
  208. 9:53And as a dad, I'm supposed to be her protector,
  209. 9:56and I just felt like I had, I had completely let her down,
  210. 10:00that...
  211. 10:06I just didn't,
  212. 10:07I mean, I just didn't know what, what to do anymore.
  213. 10:11♪ ♪
  214. 10:15LEMBKE: There was implicit trust.
  215. 10:17"If this medication were dangerous,
  216. 10:18"they would tell me.
  217. 10:20"As long as we take it just as prescribed,
  218. 10:23everything is going to be okay."
  219. 10:24And that is totally untrue.
  220. 10:26Casey's a great example.
  221. 10:29Now, given her family history of addiction,
  222. 10:31she probably had an underlying vulnerability, right?
  223. 10:33But what made her addicted
  224. 10:36was the opioids that she received from her doctors.
  225. 10:42NARRATOR: Addiction runs in families,
  226. 10:44and studies suggest
  227. 10:45that genes play a role in determining one's risk.
  228. 10:52Addiction is a complex disorder,
  229. 10:54and as a complex disorder, there's not one addiction gene.
  230. 10:58It's multiple genes
  231. 10:59and multiple other factors that interact with your genetics
  232. 11:03that increases risk.
  233. 11:06NARRATOR: Over 90% of addiction cases start before age 21,
  234. 11:11when the brain is still forming.
  235. 11:15For Jasen's brother Mark,
  236. 11:16it was a time of impulsive decisions.
  237. 11:20MARK EDWARDS: I had no idea how dangerous pain medication would be.
  238. 11:26I never woke up any day and said,
  239. 11:30"Man, I want to be an addict today."
  240. 11:33And I asked myself, "How did you end up here?"
  241. 11:38And I look back on my surroundings
  242. 11:40and everything that was around me.
  243. 11:42People everywhere was, was doing this.
  244. 11:47It was almost like there was nothing else in life.
  245. 11:51♪ ♪
  246. 11:53NARRATOR: As doctors prescribed fewer pain pills,
  247. 11:55drug cartels filled the void by selling heroin,
  248. 11:59an illegal opioid cheaper than OxyContin.
  249. 12:05Overdose deaths climbed
  250. 12:07as heroin, long available in inner cities,
  251. 12:09turned up in rural communities.
  252. 12:12♪ ♪
  253. 12:16In a single year,
  254. 12:17more than 70,000 Americans died of an overdose.
  255. 12:25Addiction is America's number one domestic issue today.
  256. 12:28We have hospitals
  257. 12:30that are overwhelmed with people who need help.
  258. 12:34We have a prison system that is filled
  259. 12:36with people who actually need treatment.
  260. 12:39We have judges
  261. 12:41that are often seeing more people with mental diseases
  262. 12:45than a psychiatrist-- or a primary care physician like me--
  263. 12:47sees in a day.
  264. 12:49The entire fabric of our society is being destroyed,
  265. 12:53as a result of addiction.
  266. 12:55♪ ♪
  267. 12:58NARRATOR: Addiction is often viewed as a moral failing--
  268. 13:02stigmatized by words like "clean," "dirty,"
  269. 13:06"abuser," "addict."
  270. 13:09But scientists now know it's a disorder
  271. 13:12that occurs as the brain changes in response to drugs.
  272. 13:17MALENKA: Individuals struggling with addiction
  273. 13:21are actually battling millions of years of evolution,
  274. 13:24because our brains are exquisitely evolved
  275. 13:28to seek rewards,
  276. 13:30to seek reinforcement wherever and whenever we can.
  277. 13:33♪ ♪
  278. 13:37NARRATOR: To understand how reward shapes behavior,
  279. 13:39Robert Malenka simulates a famous experiment.
  280. 13:44A mouse is attached to a fiber optic cable
  281. 13:47and placed in a cage with two holes.
  282. 13:50♪ ♪
  283. 13:53When the mouse explores the hole on the right,
  284. 13:55a flash of light sparks a feeling of pleasure
  285. 13:58in its brain.
  286. 14:01At the other hole, nothing happens.
  287. 14:07Yep, there he goes again, right now.
  288. 14:08(voiceover): We are learning machines.
  289. 14:12Our brains have evolved to be exquisite reward seekers,
  290. 14:16and that was important for evolutionary survival.
  291. 14:19But that came with a price--
  292. 14:22our susceptibility to developing addictions.
  293. 14:25NARRATOR: Obsessed with that burst of pleasure,
  294. 14:30the mouse will probe the hole several thousand times
  295. 14:33over the next hour.
  296. 14:35MALENKA: I mean look at this,
  297. 14:36he's just doing nothing else.
  298. 14:39NARRATOR: This experiment revealed the reward pathway in the brain,
  299. 14:44primarily controlled by a chemical messenger
  300. 14:47called dopamine.
  301. 14:50Dopamine tells your brain to pay attention,
  302. 14:53that whatever it just experienced
  303. 14:55is worth getting more of.
  304. 14:59It's released by endorphins
  305. 15:01or when we encounter anything pleasurable or exciting--
  306. 15:07especially drugs that can push dopamine levels
  307. 15:10ten times higher than normal.
  308. 15:13MALENKA: All drugs of abuse cause this unnatural rise of dopamine.
  309. 15:19And because of that,
  310. 15:21they're among the most powerful experiences
  311. 15:24our brains can have.
  312. 15:25♪ ♪
  313. 15:27NARRATOR: As drugs raise dopamine levels,
  314. 15:29they also alter the connections between brain cells,
  315. 15:33creating memoires of euphoria that trigger fierce cravings.
  316. 15:40But it's not just about seeking pleasure.
  317. 15:43People struggling with addiction
  318. 15:44soon use drugs to avoid the pain of withdrawal.
  319. 15:50JASEN: Withdrawals will make your bones ache.
  320. 15:54I couldn't leave the house because I couldn't take a step
  321. 15:58without soiling myself from the withdrawals.
  322. 16:02(shattering)
  323. 16:04You couldn't talk to me,
  324. 16:06I'd throw something at you or bite your head off.
  325. 16:10NARRATOR: When opioids are abruptly stopped,
  326. 16:13stress hormones are released at catastrophic levels.
  327. 16:18This imbalance triggers the opposite symptoms of opioid use,
  328. 16:23including shaking, anxiety, pain, and intense dysphoria.
  329. 16:29Many times I would lay my head on a pillow
  330. 16:33and think, "I'm done.
  331. 16:34I can't live like this, I don't want to be this person."
  332. 16:38And I would wake up the very next day,
  333. 16:41and I would just do more drugs.
  334. 16:43I was powerless over my addiction.
  335. 16:46It consumed me, it owned me,
  336. 16:49I was a slave to it.
  337. 16:54♪ ♪
  338. 16:59NARRATOR: This cycle of addiction, says Dr. Corey Waller,
  339. 17:03starts as the brain struggles to rebalance
  340. 17:06as drugs overwhelm it with dopamine.
  341. 17:09WALLER: When that happens,
  342. 17:10the body decreases the production of dopamine,
  343. 17:14and eventually you can't even get enough dopamine produced
  344. 17:16to get out of bed,
  345. 17:17let alone produce good relationships
  346. 17:19and good decision-making.
  347. 17:21♪ ♪
  348. 17:23NARRATOR: To understand what happens to dopamine,
  349. 17:26Dr. Nora Volkow has been imaging the brains
  350. 17:31of people with and without addiction
  351. 17:32to search for changes that occur with drug use.
  352. 17:36♪ ♪
  353. 17:40VOLKOW: We systematically were investigating
  354. 17:41individuals addicted to different classes of drugs,
  355. 17:44and we found that a common change
  356. 17:46across all of the different types of drug addictions
  357. 17:49was a reduction in the levels of dopamine D2 receptors.
  358. 17:54NARRATOR: The number of receptor proteins,
  359. 17:58seen here as red in the brains of control subjects,
  360. 18:01are reduced in brains exposed to drugs.
  361. 18:05Fewer receptors means the brain is starving for dopamine.
  362. 18:09VOLKOW: Drugs interfere with your motivational drive.
  363. 18:15So imagine what it means
  364. 18:16to lose the motivation to do things,
  365. 18:19to just not have it.
  366. 18:21WALLER: And so anytime someone hears the term motivation,
  367. 18:23they should really supplant that with dopamine.
  368. 18:26Because without dopamine, you don't have motivation.
  369. 18:29And so, when we look at a person
  370. 18:30who is in the throes of an addictive disorder,
  371. 18:33and say, "They just need to motivate!"
  372. 18:34We're telling them to somehow magically make dopamine.
  373. 18:38(tumblers spinning)
  374. 18:40NARRATOR: And it's not just drugs--
  375. 18:41gambling or eating can also spike dopamine levels
  376. 18:46and become addictive.
  377. 18:49Volkow found that people with morbid obesity
  378. 18:52also have fewer dopamine receptors.
  379. 18:57VOLKOW: Once those receptors are going down,
  380. 18:59you are going to have a great difficulty
  381. 19:04in self-regulating the desire not to eat,
  382. 19:06because cognitively, your brain is fighting.
  383. 19:09On the one hand you say, "I, I'm obese,
  384. 19:11I don't want to eat anymore."
  385. 19:12And at the same time, there is intense craving.
  386. 19:15And if your brain is not functioning properly,
  387. 19:19you cannot win the game.
  388. 19:22You are going to give in
  389. 19:24and impulsively and compulsively eat that food.
  390. 19:28NARRATOR: And drugs can unleash even stronger cravings.
  391. 19:34JASEN: My wife at the time
  392. 19:35went and seen her sister for nine days,
  393. 19:39and I spent $21,000 while she was gone...
  394. 19:41(chuckles sardonically)
  395. 19:44on pain medicine.
  396. 19:46I did lose my job, I didn't care.
  397. 19:50Only thing I cared about
  398. 19:53was that magical date on the calendar
  399. 19:54when I went back to the doctor.
  400. 19:55WALLER: The body has a drive for dopamine,
  401. 19:59and that craving flips them into survival mode.
  402. 20:03If you understand that this is about survival for them,
  403. 20:05you can understand why they steal $20 out of your wallet,
  404. 20:10why they hock jewelry from the house.
  405. 20:13JASEN: My habits was putting my wife and my daughter in danger.
  406. 20:18Finally, she just done what any mother would do,
  407. 20:21and they left.
  408. 20:24♪ ♪
  409. 20:27NARRATOR: Jasen attempted suicide
  410. 20:29after his brother Scott died of an overdose
  411. 20:31on the outskirts of town.
  412. 20:35For Mark Edwards,
  413. 20:36it was a moment of reckoning with his own addiction.
  414. 20:40MARK: I did not want to be that person that was broken.
  415. 20:44And I wanted to get help,
  416. 20:47but every place that I called didn't have beds available.
  417. 20:51I felt like that
  418. 20:52if I didn't do something,
  419. 20:54that I would end up dead.
  420. 20:58♪ ♪
  421. 21:01NARRATOR: Another drug is making the epidemic even deadlier,
  422. 21:06especially in Vancouver, Canada.
  423. 21:11The city has become a gateway for illegal fentanyl,
  424. 21:14made in China.
  425. 21:17Normally used for anesthesia, fentanyl is so potent,
  426. 21:21it's often shipped a few ounces at a time
  427. 21:24and later mixed with other drugs.
  428. 21:28Hidden in innocuous-looking packages,
  429. 21:31much of China's fentanyl is headed for U.S. markets.
  430. 21:36But it's also devastating Vancouver.
  431. 21:42FISHER: Fentanyl is a synthetic opiate created in a lab.
  432. 21:45It is super toxic.
  433. 21:46So you'll get a batch that comes on the street
  434. 21:48that's a little bit hot.
  435. 21:50And on those days, it's like,
  436. 21:51bam, somebody's going down, bam, somebody's going down,
  437. 21:53bam!
  438. 21:57NARRATOR: Up to 50 times stronger than heroin,
  439. 21:59an amount of fentanyl equal in size
  440. 22:01to two grains of salt
  441. 22:03will kill you.
  442. 22:05(siren blaring)
  443. 22:09Fentanyl's path of destruction
  444. 22:11is closely monitored in West Virginia
  445. 22:14by Dr. Rahul Gupta.
  446. 22:16Using a digital map,
  447. 22:20Gupta follows overdoses as they occur.
  448. 22:23Circles stand for non-lethal incidents.
  449. 22:28Squares indicate fatal ones.
  450. 22:31And a spike of deaths in nearby states
  451. 22:35means fentanyl-tainted drugs may soon show up
  452. 22:38in West Virginia.
  453. 22:39♪ ♪
  454. 22:42GUPTA: On one day, we had 26 overdoses reported to us.
  455. 22:47It was almost like a communicable disease outbreak.
  456. 22:50And here's the scariest part.
  457. 22:51We found that of all of those people who overdosed,
  458. 22:55none-- no one--
  459. 22:57was ever admitted into a treatment facility.
  460. 23:01(radios squawking)
  461. 23:03NARRATOR: But many people don't survive at all
  462. 23:06because opioids, if taken in excess,
  463. 23:08can quickly shut down breathing.
  464. 23:11Hello?
  465. 23:12NARRATOR: And because of the potency of fentanyl,
  466. 23:15the risk of a fatal overdose is high,
  467. 23:19no matter who you are or where you live.
  468. 23:23♪ ♪
  469. 23:31MARY WINNEFELD: Jonathan was a wonderful young man.
  470. 23:33From a very early age, compassionate, smart, loving.
  471. 23:39Our family did go through many moves.
  472. 23:42We lived all over this country, overseas.
  473. 23:45So that was, I think, tough for Jonathan.
  474. 23:49NARRATOR: Jonathan Winnefeld was born into an accomplished family.
  475. 23:57His father James rose through the naval ranks
  476. 24:00to become the Vice Chairman of the Joint Chiefs of Staff
  477. 24:03in 2011.
  478. 24:07By that time, Jonathan was struggling.
  479. 24:10JAMES: At one point, he was in five different school districts
  480. 24:14in six years, which is tough for a kid.
  481. 24:16And so what became apparent to us over time
  482. 24:19was that Jonathan, as great a kid as he was,
  483. 24:22was suffering from some form of anxiety and depression.
  484. 24:27NARRATOR: Unfortunately, Jonathan was misdiagnosed
  485. 24:29with attention deficit disorder,
  486. 24:32and prescribed Adderall, a powerful stimulant.
  487. 24:37Soon, to unwind at night, he began to drink.
  488. 24:43To calm his anxiety,
  489. 24:45he used Xanax, a mild tranquilizer,
  490. 24:48and smoked pot.
  491. 24:50Then, he experimented with heroin.
  492. 24:55MARY: So we got him into counseling,
  493. 24:57and I did what a normal parent would do.
  494. 25:01I took away the Xbox,
  495. 25:02I took away his phone, I monitored all of his moves.
  496. 25:06In retrospect,
  497. 25:08it was probably the worst thing I could have done for him,
  498. 25:10because it isolated him even more.
  499. 25:13(sirens blaring)
  500. 25:14JAMES: And, ultimately, he tried to take his own life.
  501. 25:17He ended up wrapping his car around a telephone pole.
  502. 25:22It was at that point when we realized
  503. 25:23that we needed to get Jonathan into inpatient treatment
  504. 25:25or we were going to lose him.
  505. 25:27(typing on keyboard)
  506. 25:29MARY: I went on the internet and searched,
  507. 25:31and it's overwhelming.
  508. 25:33There are so many different places out there.
  509. 25:35You don't know who's good, who's bad,
  510. 25:37who's just trying to make money.
  511. 25:39Financially, our insurance covered nothing.
  512. 25:42We really tried to find the best treatment possible out there.
  513. 25:45But, in America, there's not a lot of support
  514. 25:48in the mental health
  515. 25:50and especially in substance abuse.
  516. 25:55NARRATOR: The Winnefelds found a center in Connecticut
  517. 25:57to treat Jonathan's addiction and anxiety.
  518. 26:02Like some 80% of programs,
  519. 26:03it followed the 12-step model of Alcoholics Anonymous,
  520. 26:07where patients admit they are powerless over drugs,
  521. 26:10need help from a higher power, and commit to abstinence.
  522. 26:16WALLER: If we look at the legacy treatments
  523. 26:19that've been around for 70 years,
  524. 26:21they revolve around going to meetings
  525. 26:22and working through the 12 steps,
  526. 26:25generally doing that a lot
  527. 26:27with self-help and group-based therapy,
  528. 26:29and then maintaining that abstinence
  529. 26:32by using that alone.
  530. 26:33NARRATOR: Jonathan's treatment for 15 months
  531. 26:37cost the Winnefelds hundreds of thousands of dollars,
  532. 26:41but it seemed worth it.
  533. 26:46JAMES: Our son came back to us.
  534. 26:49We were able to have a real conversation with him.
  535. 26:51We saw, about a year into his treatment,
  536. 26:53that he regained his ambition.
  537. 26:56♪ ♪
  538. 26:58NARRATOR: Seeming confident of his recovery,
  539. 27:00Jonathan enrolled as a freshman at the University of Denver.
  540. 27:05JAMES: That day we dropped him off at his dorm,
  541. 27:07he was excited, looking good, fired up,
  542. 27:11and it was one of the best moments of my life,
  543. 27:13seeing him doing so well.
  544. 27:16(phone vibrating)
  545. 27:20NARRATOR: Three days later,
  546. 27:22their hopes were shattered.
  547. 27:25MARY: I was not prepared to get a phone call
  548. 27:29saying that my son had passed away
  549. 27:31in his bed, in his dorm room, from heroin and fentanyl.
  550. 27:36Never, never, never would have guessed that
  551. 27:39in a million years.
  552. 27:43♪ ♪
  553. 27:45NARRATOR: With failure rates nearing 80% to 90%,
  554. 27:48is the abstinence-based approach to opioid addiction
  555. 27:52scientifically flawed?
  556. 27:55Abstinence-based programs really, for opioid use disorder,
  557. 28:00are setting people up to fail and to relapse.
  558. 28:02And in the face of this crisis,
  559. 28:05where we know that every single time
  560. 28:07that somebody uses an opioid,
  561. 28:09they are at real risk of overdosing and dying,
  562. 28:12this should never be recommended as a primary intervention.
  563. 28:20NARRATOR: In Morgantown, West Virginia,
  564. 28:22Dr. James Berry also believed abstinence-based treatment
  565. 28:26was failing his patients with opioid addiction.
  566. 28:30(nurse talking indistinctly)
  567. 28:31BERRY: We would get them successfully detoxed,
  568. 28:34get them exposed to family therapy,
  569. 28:36group therapy, individual therapy,
  570. 28:39and we'd find that they would invariably relapse,
  571. 28:42and they'd just be out there on the streets using again.
  572. 28:45♪ ♪
  573. 28:47NARRATOR: Frustrated, Berry considered using methadone,
  574. 28:49a long-lasting opioid
  575. 28:51that curbs cravings from heroin and pain pills
  576. 28:55without causing euphoria.
  577. 28:57Methadone binds to opioid receptors
  578. 29:01and normalizes brain functions altered by addiction,
  579. 29:05including dopamine levels.
  580. 29:08Here is your medication, sir.
  581. 29:10NARRATOR: Under current laws,
  582. 29:11most patients must take it at clinics.
  583. 29:13Here is your medication, sir.
  584. 29:15NARRATOR: In 2003, the opioid buprenorphine
  585. 29:19became available under the brand name Suboxone,
  586. 29:23which could be taken at home.
  587. 29:27Less potent than methadone,
  588. 29:30Suboxone only partially activates opioid receptors
  589. 29:33to reduce cravings.
  590. 29:36If taken as prescribed and not misused,
  591. 29:39both drugs cut mortality by about half.
  592. 29:43After a year,
  593. 29:4640% to 90% of patients are in recovery.
  594. 29:49You feeling better?
  595. 29:51NARRATOR: Berry began giving patients Suboxone.
  596. 29:54Oh, yeah, 100%.
  597. 29:55They started doing well,
  598. 29:56they started getting their lives back,
  599. 29:58they started getting to work again.
  600. 30:00Uh, Lawrence, how are you?
  601. 30:01Good.
  602. 30:02And how much time do you got today?
  603. 30:04I got like 260 or...
  604. 30:06BERRY: 245 days!
  605. 30:08245, okay, yeah.
  606. 30:10Tell us what you have been doing the last two weeks.
  607. 30:11Work has picked up.
  608. 30:13I'm about to buy into my boss's business,
  609. 30:14yeah 35%.
  610. 30:16He's gonna let me buy in.
  611. 30:16No kidding!
  612. 30:17So that will be awesome for me.
  613. 30:19So you've really showed him what you've been able to do.
  614. 30:20Yeah, yeah.
  615. 30:22The main thing that makes Suboxone so effective
  616. 30:24is it's helping with these cravings
  617. 30:27that people are experiencing.
  618. 30:29But it's so hard to break that chain.
  619. 30:31BERRY: Patient after patient after patient
  620. 30:34will tell me the same story.
  621. 30:35"Listen, Doc,
  622. 30:36"I am not using to get high anymore.
  623. 30:39I am just using not to be sick anymore."
  624. 30:41What Suboxone does is
  625. 30:44it satisfies those cravings
  626. 30:46in a way that they're under control.
  627. 30:49It works so much better
  628. 30:52on calming that demon inside you.
  629. 30:53If I went home,
  630. 30:56started doing opiates again,
  631. 30:58I was going to kill myself.
  632. 30:59(indistinct talking)
  633. 31:01NARRATOR: With cravings under control,
  634. 31:03patients can take advantage of a range of therapies
  635. 31:06to help them cope and rebuild their lives.
  636. 31:12LEMBKE: There are fantastic psychosocial interventions
  637. 31:16like retraining your brain, being mindful,
  638. 31:19learning more adaptive coping strategies.
  639. 31:21The night before, I was saying...
  640. 31:23CARRIE WILKINS: Because it's not just one epiphany moment.
  641. 31:26It's a learning process.
  642. 31:27You have to learn to be sober.
  643. 31:29And it takes practice, it takes trial and error.
  644. 31:31And you've got to be ready for the ups and downs.
  645. 31:35♪ ♪
  646. 31:38NARRATOR: One challenge, according to psychologist Rita Goldstein,
  647. 31:42are the changes that occur with addiction
  648. 31:44in the brain's executive control center,
  649. 31:46the prefrontal cortex.
  650. 31:49This is the prefrontal cortex, in the front of the brain.
  651. 31:54And we're looking at gray matter,
  652. 31:55separating it from the white matter.
  653. 31:58So you can see,
  654. 31:59it's actually tinted gray in this scan.
  655. 32:01♪ ♪
  656. 32:03NARRATOR: Scans reveal that chronic drug use
  657. 32:06is associated with reduced grey matter,
  658. 32:09especially in the prefrontal cortex.
  659. 32:14GOLDSTEIN: Those regions are essential to make advantageous choices--
  660. 32:18to make the right decision at the right time.
  661. 32:21So, the lower the gray matter,
  662. 32:23the more the decision-making is impaired.
  663. 32:25You have a decrease
  664. 32:27in the ability to control your behavior.
  665. 32:31NARRATOR: Neuroscientist Yasmin Hurd
  666. 32:34has found another way
  667. 32:35that chronic drug use impacts the brain.
  668. 32:39By analyzing the brains of overdose victims,
  669. 32:43she's discovered that heroin changes the activity
  670. 32:46of key genes.
  671. 32:50Heroin changes the way our DNA functions.
  672. 32:52It turns on genes that should not be on.
  673. 32:56And turns off genes that should be on.
  674. 32:58And so that imbalance changes the brain function.
  675. 33:02♪ ♪
  676. 33:05NARRATOR: The genes most affected
  677. 33:06regulate the brain's key chemical messenger,
  678. 33:08called glutamate,
  679. 33:11which is essential for sending signals between neurons,
  680. 33:13making thinking, memory, and learning possible.
  681. 33:20HURD: It's not that addiction completely takes away
  682. 33:22every aspect of your cognitive function.
  683. 33:25In fact, you have to work even harder.
  684. 33:27So I think people need to understand
  685. 33:29that people with these disorders
  686. 33:30are actually fighting a very strong battle.
  687. 33:35NARRATOR: But is this a battle that can be fought and won?
  688. 33:40Opioids are still being studied,
  689. 33:42but scans reveal
  690. 33:44that dopamine receptors reduced by other addictive drugs
  691. 33:48can come back with recovery.
  692. 33:52Rita Goldstein has seen evidence that grey matter can increase.
  693. 33:58The ability of the brain to heal and to recover is amazing.
  694. 34:01So definitely there is a lot of hope.
  695. 34:04HURD: The question is,
  696. 34:06"How long does it take?"
  697. 34:07And everyone's brain is different.
  698. 34:10(siren blaring)
  699. 34:14NARRATOR: Yet most people don't have access
  700. 34:16to effective treatment,
  701. 34:18especially medications for opioid addiction.
  702. 34:21♪ ♪
  703. 34:23For Dr. Corey Waller,
  704. 34:25the problem is that addiction is not handled
  705. 34:27like other diseases.
  706. 34:29WALLER: If a patient comes into an emergency department
  707. 34:32with chest pain,
  708. 34:33we have a pretty standard set of approaches.
  709. 34:35We evaluate whether or not the heart's being injured.
  710. 34:38We look at an E.K.G. that tells me,
  711. 34:40"Do they need to get something done quickly?"
  712. 34:43And no matter what the answer is,
  713. 34:44we actually have a place for them to go.
  714. 34:48NARRATOR: For overdose victims, the focus is mainly on revival.
  715. 34:55These are patients who are basically dead.
  716. 34:57They're not breathing.
  717. 34:58They are this close to being dead forever.
  718. 35:01WALLER: Let's give the Narcan real quick.
  719. 35:02NARRATOR: The drug naloxone,
  720. 35:04sold under the brand name Narcan,
  721. 35:06can reverse an overdose
  722. 35:08by pulling opioids off receptors in the brain.
  723. 35:11You all right?
  724. 35:12Good.
  725. 35:15WALLER (voiceover): And in most emergency departments around the country,
  726. 35:16that's the extent of the intervention.
  727. 35:19Check the box, sign the chart, discharge the patient.
  728. 35:22Unfortunately, we discharge them back out into the wilderness,
  729. 35:25where there is no consolidated, appropriate care for them.
  730. 35:29Big, deep breaths.
  731. 35:30NARRATOR: Although Narcan saves lives,
  732. 35:33it can also put patients into acute withdrawal.
  733. 35:37Without medications to control cravings,
  734. 35:41many will overdose again.
  735. 35:45WOMAN: Oh, my God.
  736. 35:48(child crying)
  737. 35:52KEHOE: This human tragedy really is a human rights issue.
  738. 35:58The last thing we should be doing
  739. 35:59is kicking people out of care.
  740. 36:00That's when they're in crisis.
  741. 36:01♪ ♪
  742. 36:04NARRATOR: Massachusetts General Hospital
  743. 36:06runs one of the few programs in the U.S.
  744. 36:09that immediately offers overdose patients medications
  745. 36:12to control cravings.
  746. 36:16KEHOE: This is a treatable illness.
  747. 36:19We have to have people in that moment
  748. 36:21who can say, "Hey, I'm here to help you.
  749. 36:24"Are you interested in engaging in care?
  750. 36:26We have Suboxone we can start you on right away."
  751. 36:31We're seeing people come that day
  752. 36:32and engage in care,
  753. 36:33and the vast majority of them, 75% to 80%,
  754. 36:37are returning.
  755. 36:38♪ ♪
  756. 36:40What's going on here? Did we tolerate it?
  757. 36:42NARRATOR: Since effective treatment is hard to find,
  758. 36:44the costs of the epidemic continue to rise.
  759. 36:49In Charleston, West Virginia,
  760. 36:52Dr. Stefan Maxwell cares for babies born dependent on drugs.
  761. 36:56(baby wailing)
  762. 36:58MAXWELL: It's a withdrawal syndrome.
  763. 37:01They have vomiting, diarrhea.
  764. 37:04Frantic behavior, they may scratch themselves.
  765. 37:06These babies may go for many days without sleeping
  766. 37:11or eating.
  767. 37:12And symptoms may last up to three months.
  768. 37:16NURSE: I know, baby, I know.
  769. 37:17NARRATOR: Babies in acute withdrawal are weaned off opioids
  770. 37:21by giving them smaller and smaller doses.
  771. 37:25I just gave her a methadone about five minutes ago.
  772. 37:30NARRATOR: Every 25 minutes,
  773. 37:32somewhere in the U.S.,
  774. 37:34a baby is born dependent on opioids.
  775. 37:38Many will become wards of the state.
  776. 37:44We have amongst the highest number of foster children
  777. 37:47in the nation per capita.
  778. 37:48We're having difficulty finding parents
  779. 37:51and providing services.
  780. 37:53In fact, we believe it cost
  781. 37:55over a million dollars per child additionally
  782. 37:58if they're born dependent on drugs.
  783. 38:02♪ ♪
  784. 38:04NARRATOR: Many parents with addiction are also facing challenges
  785. 38:08like poverty and trauma.
  786. 38:12BESSEL VAN DER KOLK: Trauma is an experience that overwhelms you,
  787. 38:16that leaves you bereft, paralyzed,
  788. 38:19and with no way out.
  789. 38:21And it can come in many different contexts.
  790. 38:24It can be physical, verbal, sexual abuse,
  791. 38:28childhood neglect.
  792. 38:29And these problems early in life
  793. 38:32put you at risk later in life.
  794. 38:35NARRATOR: Studies show experiencing a combination
  795. 38:38of five adverse events
  796. 38:40can increase the risk of addiction tenfold.
  797. 38:45Trauma can cause long-lasting changes in the brain,
  798. 38:49leaving sufferers like Marie
  799. 38:50also vulnerable to depression and anxiety.
  800. 38:56We had somewhat of a decent family life, you know,
  801. 38:59but I watched my dad beat my mom my whole life, you know.
  802. 39:02My dad was an alcoholic.
  803. 39:04They finally divorced,
  804. 39:06and me and my mom moved out here.
  805. 39:07And my mom kind of lost it.
  806. 39:11That's when I started
  807. 39:12really, just, you know, going wild.
  808. 39:14VAN DER KOLK: What you're left with as a kid,
  809. 39:17is these heartbreaking feelings
  810. 39:19of "I'm no good" and "The world is a terrible place."
  811. 39:23Somebody says to you,
  812. 39:25"Here is something that will make these feelings go away."
  813. 39:29And so, people take drugs
  814. 39:30because they can't stand the way they feel.
  815. 39:33NARRATOR: After Marie had her first child,
  816. 39:37she became addicted to OxyContin.
  817. 39:41Child Protective Services took custody of her son
  818. 39:44until she could pass her drug tests.
  819. 39:48For a while, things went well.
  820. 39:53But Marie began struggling
  821. 39:55after giving birth to her second child.
  822. 39:59MARIE: I went home to see my first son,
  823. 40:01you know, because I hadn't been spending time with him.
  824. 40:04And then I got a phone call,
  825. 40:05and CPS said, "Get ready,
  826. 40:07"'cause we got to meet you in Charleston
  827. 40:08to take your kids."
  828. 40:12NARRATOR: During her pregnancy,
  829. 40:14Marie had been given methadone for free.
  830. 40:17But after her delivery,
  831. 40:19she had to pay for her treatment.
  832. 40:24With no money or insurance, she relapsed.
  833. 40:28It's a reality faced by countless people
  834. 40:31without resources.
  835. 40:33MARIE: By that time
  836. 40:35I owed the methadone clinic over $600 and some, you know.
  837. 40:39And, of course, when you go back, you know,
  838. 40:40they wouldn't see you no more
  839. 40:41because I owed them too much money.
  840. 40:43So I couldn't, I couldn't dose no more,
  841. 40:45so here I am back at it again, you know.
  842. 40:48(sniffles)
  843. 40:50MARY PRICE: She needed services that were lacking
  844. 40:53here in rural West Virginia.
  845. 40:56She needed those to be available for her,
  846. 40:58and they're not.
  847. 41:00And that saddens me, because...
  848. 41:04because I know...
  849. 41:07that the mom's hearts break.
  850. 41:12(radio squawking)
  851. 41:13MARIE: I'll never forget that whole scene in my life.
  852. 41:18they surrounded us with cops,
  853. 41:19and that was not needed, you know.
  854. 41:21And my three-year-old said, "Mommy,
  855. 41:23hold my hat while I'm gone."
  856. 41:26(voice breaking): And...
  857. 41:27they took him away.
  858. 41:34WALLER: People always want to talk about,
  859. 41:36"How do we stop the cycle?"
  860. 41:39That's how we stop the cycle.
  861. 41:40You don't stop the cycle by pulling the baby
  862. 41:42because mom took drugs.
  863. 41:45We just need to see it and treat it
  864. 41:46like it's any other disease.
  865. 41:48You get the mom stable, you get baby stable,
  866. 41:51and you go home with a family.
  867. 41:53♪ ♪
  868. 41:57NARRATOR: Back in Vancouver,
  869. 41:59the opioid epidemic spurred the city to take bold steps,
  870. 42:03even before fentanyl tainted the drug supply.
  871. 42:08In 2003 it sanctioned the first legal site in North America
  872. 42:13where people could inject illegal drugs
  873. 42:16under medical supervision.
  874. 42:19Called Insite,
  875. 42:21the program provides clean needles
  876. 42:23to prevent the spread of infectious diseases,
  877. 42:25drugs to reverse overdoses,
  878. 42:28and help accessing services,
  879. 42:29like medically assisted treatment.
  880. 42:34FISHER: When people come to Insite,
  881. 42:36often the first thing that they're thinking is,
  882. 42:38"I need a safer place to use.
  883. 42:40"I don't want to die in the alley.
  884. 42:42"I'm tired of living in, essentially,
  885. 42:43what are Third World conditions."
  886. 42:45So what we're doing is we're saying,
  887. 42:47"Come on in to First World health care."
  888. 42:49And in the years since Insite's opened,
  889. 42:52overdoses in the area have gone down,
  890. 42:54and our H.I.V. rate in Vancouver has plummeted dramatically.
  891. 42:57NARRATOR: Insite's success bolstered other efforts.
  892. 43:02At the Overdose Prevention Society,
  893. 43:06Sarah Blythe helps people test their drugs for fentanyl.
  894. 43:11But that's not the only contaminant
  895. 43:13she's worried about.
  896. 43:16BLYTHE: Because we've seen everything
  897. 43:17from cement filler to Comet to pig de-wormer,
  898. 43:22like, you name it,
  899. 43:23anything that they can put in there,
  900. 43:25they do, and it's dangerous.
  901. 43:27NARRATOR: A pink stripe indicates the presence of fentanyl.
  902. 43:31It's now found in 88% of illegal opioids here.
  903. 43:38Like many longtime users,
  904. 43:40Daniel knows he's injecting fentanyl,
  905. 43:45but the fear of dying
  906. 43:46isn't as powerful as his cravings.
  907. 43:52He first took opioids in prison to calm his anxiety.
  908. 43:58There's always a fear
  909. 44:00of something horrible about to happen.
  910. 44:02There's going to be somebody getting stabbed,
  911. 44:04a fight's going to break out.
  912. 44:05And so when I did that first hit,
  913. 44:08it was the first time I felt like I could relax
  914. 44:12and not have to worry.
  915. 44:13♪ ♪
  916. 44:17FISHER: To my mind,
  917. 44:18obviously the most important thing
  918. 44:20about supervised injection sites
  919. 44:22is that it implicitly says that,
  920. 44:24"These lives are worth saving,
  921. 44:26these people are valuable to us."
  922. 44:28What's really important about it as well
  923. 44:29is that it's a space of connection.
  924. 44:31That's the space that people are going to ask for help from.
  925. 44:37NARRATOR: Supervised injection sites are illegal in the U.S.,
  926. 44:42but in Canada, the controversy is waning.
  927. 44:46For 22 years, Bill Spearn has walked the streets
  928. 44:51of the downtown east side.
  929. 44:54Although drugs are still here,
  930. 44:56overdose deaths decreased 35%
  931. 44:59after Insite opened.
  932. 45:04Once a skeptic of supervised injection sites,
  933. 45:07today he's not.
  934. 45:10SPEARN: Does it increase crime?
  935. 45:12Does it encourage drug use?
  936. 45:14Is Insite a big magnet that attracts drug users
  937. 45:17from all over the world?
  938. 45:18And the answer is no, it doesn't.
  939. 45:21And I think that harm reduction
  940. 45:23is something that every city should consider,
  941. 45:26because it keeps people alive.
  942. 45:29FISHER: It actually saves taxpayers dollars.
  943. 45:31The most expensive housing that we have in this society?
  944. 45:37Emergency rooms and jail cells.
  945. 45:40We need to quit putting people in those
  946. 45:42and start putting people in more compassionate spaces
  947. 45:45like supervised injection sites.
  948. 45:46♪ ♪
  949. 45:51NARRATOR: Meanwhile in West Virginia,
  950. 45:53heath commissioner Dr. Rahul Gupta,
  951. 45:56is also trying to reverse
  952. 45:58the soaring number of overdose deaths.
  953. 46:02Today he's traveling with a volunteer medical team
  954. 46:05to bring free health care to McDowell County
  955. 46:08and take steps to stop preventable deaths.
  956. 46:16GUPTA: This is naloxone.
  957. 46:18NARRATOR: Because overdose fatalities here
  958. 46:21are seven times the national average,
  959. 46:23Gupta and his colleagues are trying to get naloxone,
  960. 46:26the overdose reversal drug,
  961. 46:28to as many people as possible.
  962. 46:30That's how this drug works to save your life,
  963. 46:33okay?
  964. 46:34But after that you've got to get help as well.
  965. 46:37I don't look at this as a single epidemic.
  966. 46:39I look at this as multiple epidemics
  967. 46:41coming together and evolving in real time.
  968. 46:44NARRATOR: Gupta is worried
  969. 46:47about the huge spike in hepatitis
  970. 46:49and the rising number of H.I.V. cases.
  971. 46:52Patients are offered free testing
  972. 46:56to see if they need treatment.
  973. 46:58VOLUNTEER: It just takes 20 minutes.
  974. 47:01Now, I also want to talk to you about a needle exchange,
  975. 47:03are you okay with that? Okay.
  976. 47:05NARRATOR: McDowell is one of the few counties
  977. 47:09that allows needles to be handed out to prevent infections.
  978. 47:12Okay?
  979. 47:13The idea here is to have your own set.
  980. 47:16NARRATOR: According to Gupta's analysis,
  981. 47:19every dollar spent on harm reduction
  982. 47:21saves up to seven dollars in medical costs
  983. 47:24and steers people towards treatment.
  984. 47:27...when you do want to get help,
  985. 47:29whether it's counseling or any other aspect,
  986. 47:31we're here to help you.
  987. 47:32♪ ♪
  988. 47:34The cost are really unsustainable
  989. 47:36if we continue this path,
  990. 47:38losing over half a trillion dollars a year
  991. 47:40for multiple years in our economy.
  992. 47:43We've got to be smart about addressing addiction.
  993. 47:47We have to find ways
  994. 47:49to prevent it from happening in the first place.
  995. 47:51VOLKOW: As a country,
  996. 47:53we have neglected it,
  997. 47:55and we have stigmatized it, and we have criminalized it,
  998. 47:58and that has not solved the problem.
  999. 48:00In fact, it has made it worse.
  1000. 48:02NARRATOR: But America's addiction crisis is not just limited to opioids.
  1001. 48:09Each year over 80,000 people die from excessive drinking.
  1002. 48:15Smoking is responsible for over 400,000 deaths.
  1003. 48:23And so if we don't build a stabilized, appropriate,
  1004. 48:27evidenced-based treatment system for addiction,
  1005. 48:29then the reason that medicine gets so costly every year
  1006. 48:34is because what we're trying to do
  1007. 48:36is not intervene on the front end,
  1008. 48:39we're trying to fix everything that's broken on the back end.
  1009. 48:41The solution to this
  1010. 48:43is for us to embrace addiction as a disease,
  1011. 48:47to bring it within the house of medicine,
  1012. 48:48so that anybody struggling with addiction
  1013. 48:51can walk into an emergency room,
  1014. 48:53or a pediatrician's office,
  1015. 48:55say, "I'm having a problem with drugs or alcohol,
  1016. 48:58will you help me?"
  1017. 49:00And that the answer is an enthusiastic "Yes!"
  1018. 49:03(turn signal ticking)
  1019. 49:06NARRATOR: Today most people struggling with opioid addictions
  1020. 49:08cannot access medications
  1021. 49:10or treatments proven to be effective.
  1022. 49:17Some people recover on their own,
  1023. 49:19but it's rare.
  1024. 49:23Jasen is one who beat the odds.
  1025. 49:26He is remarried
  1026. 49:28and delivers cars for his brother Mark's business.
  1027. 49:32♪ ♪
  1028. 49:33JASEN: I am not the man that I want to be,
  1029. 49:37but I'm not the man I used to be, thank God.
  1030. 49:39I try to become better every day.
  1031. 49:43Sometimes I fail, sometimes I succeed.
  1032. 49:46But I keep trying.
  1033. 49:47(cooing)
  1034. 49:49NARRATOR: Mark recovered after five years of methadone treatment,
  1035. 49:53followed by a faith-based program.
  1036. 49:56MARK: And that love began to change me
  1037. 50:00in a way that I didn't think would ever be possible.
  1038. 50:03Shoot!
  1039. 50:05Oh, good shot!
  1040. 50:09NARRATOR: Casey is now on Suboxone
  1041. 50:11and studying to become a doctor.
  1042. 50:15Her muscle cramps have been diagnosed
  1043. 50:17as fibromyalgia
  1044. 50:19and rheumatoid arthritis.
  1045. 50:23To control her symptoms,
  1046. 50:25she takes 11 other medications,
  1047. 50:28but none are opioids.
  1048. 50:31Happy...
  1049. 50:33(voiceover): Recovery is definitely possible.
  1050. 50:35It might take years or months or however long,
  1051. 50:39but it is possible.
  1052. 50:40♪ ♪
  1053. 50:44NARRATOR: Marie is on Suboxone and getting group therapy,
  1054. 50:48paid for by Medicaid.
  1055. 50:51Today, she is going to see her youngest son,
  1056. 50:54who lives with a foster family.
  1057. 50:59Bubby, come here.
  1058. 51:02What are you doing?
  1059. 51:05Get me in!
  1060. 51:06Come here and give me a hug, Booga!
  1061. 51:09Mmm, I love you.
  1062. 51:12(voiceover): That baby means so much to me.
  1063. 51:15Now that I'm getting it together,
  1064. 51:17I hope that as time goes by,
  1065. 51:19they'll see a difference in me, you know.
  1066. 51:21NARRATOR: As long as Marie is in recovery,
  1067. 51:24she can visit her children.
  1068. 51:25Ready?
  1069. 51:26I want to go with you.
  1070. 51:28I wish you could go with me, Bubby.
  1071. 51:30I want you to go with me, if you only knew.
  1072. 51:34If you only knew.
  1073. 51:36FISHER: People recover from addiction.
  1074. 51:38They need basic stability, stability of relationships,
  1075. 51:43they need housing,
  1076. 51:44they need that sense of a future that they can look forward to.
  1077. 51:49When we offer people things like that,
  1078. 51:51they get better.
  1079. 51:52They are better.
  1080. 51:54Nobody is unreclaimable.
  1081. 52:01♪ ♪
  1082. 52:17♪ ♪
  1083. 52:32To order this "NOVA" program on DVD,
  1084. 52:35visit ShopPBS or call 1-800-PLAY-PBS.
  1085. 52:40This program is also available on Amazon Prime Video.
  1086. 52:45♪ ♪

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